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Blood Substitutes
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Book Synopsis Blood Substitutes, Present and Future Perspectives by : E. Tsuchida
Download or read book Blood Substitutes, Present and Future Perspectives written by E. Tsuchida and published by Elsevier. This book was released on 1999-01-14 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains the selected papers presented at the seventh International Symposium on Blood Substitutes (7th ISBS) held at the International Conference Center of Waseda University in Tokyo on 7-10 September 1997. In keeping with the scientific design of the 7th ISBS Symposium, chapters have been carefully selected and organized to showcase the advancements in recent research. This book includes up-to-date clinical results of leading companies which are manufacturing hemoglobin-based or fluorocarbon-based blood substitutes, and covers issues of hemoglobin toxicity and side effects such as vasoconstriction in more detail using carefully designed in vivo and ex vivo techniques. This book is also a collection of various new types of red cell substitutes such as recombinant Hbs, recombinant albumine-lipidheme complex, modified red blood cells, and perfluorochemicals using material science and molecular engineering.
Author :Forum on Blood Safety and Blood Availability Publisher :National Academies Press ISBN 13 :0309589622 Total Pages :132 pages Book Rating :4.3/5 (95 download)
Book Synopsis Blood Donors and the Supply of Blood and Blood Products by : Forum on Blood Safety and Blood Availability
Download or read book Blood Donors and the Supply of Blood and Blood Products written by Forum on Blood Safety and Blood Availability and published by National Academies Press. This book was released on 1996-08-09 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume discusses the current state of the nation's blood supply--including studies of blood availability, ways of enhancing blood collection and distribution, frozen red cell technology, logistical concerns in prepositioning frozen blood, extended liquid storage of red cells, and blood substitutes.
Book Synopsis Blood Substitutes by : Robert M. Winslow
Download or read book Blood Substitutes written by Robert M. Winslow and published by Elsevier. This book was released on 2005-10-05 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: Blood substitutes are solutions designed for use in patients who need blood transfusions, but for whom whole blood is not available, or is not safe. This interest has intensified in the wake of the AIDS and hepatitis C epidemics. Blood Substitutes describes the rationale, current approaches, clinical efficacy, and design issues for all blood substitutes now in clinical trials. The many summary diagrams and tables help make the book accessible to readers such as surgeons and blood bankers, who have less technical expertise than the biochemists and hematologists who are designing and testing blood substitutes. * Includes chapters necessary to the understanding of blood substitutes, including history, toxicity, physiology, and clinical applications * Presents detailed descriptions of the various products that have been developed and have advanced to clinical trials, and some that are in earlier states of development
Book Synopsis Blood Substitutes by : Robert M. Winslow
Download or read book Blood Substitutes written by Robert M. Winslow and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 219 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is not a "proceedings" volume. Rather the chapters are essays by experts in the field of blood substitutes, invited by the editors to con tribute to the 1996 "Current Issues in Blood Substitutes Research and Development" course given in San Diego, March 18-21. The contributors were selected because of their expertise in areas deemed by the editors to be critical to the advancement of the field. The course, as in past years, is heavily influenced by feedback from par ticipants, and by research in this and related fields. In addition to the didactic lectures (for which these chapters are the foundation), the course also offers the opportunity for presentation of research reports, progress reports from the various companies currently commercializing products, and round table discussions of selected subjects. Thus, we are grateful to past participants for their helpful comments. Production of a book, especially on a short timeline, is not an easy feat.
Book Synopsis Advances in Blood Substitutes by : R. Winslow
Download or read book Advances in Blood Substitutes written by R. Winslow and published by Springer Science & Business Media. This book was released on 1997-09-23 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: Each chapter of this volume is a contribution from an expert in the field, chosen by the editors to contribute to the 1997 "Current Issues in Blood Substitute Research and Development" course given in San Diego, March 17-19. The contributors were selected because of their expertise in areas which the editors believe to be critical to the advancement of the field, and which reflect activity in "hot" areas of relevant research. While there is a continuity in style for the annual course, each year brings changes in emphasis and content. In previous years, we were often not able to provide time for participants to present their views and opinions. Consequently, this year we encouraged discussion after each presentation. These sessions were recorded, transcribed, and are printed with the chapters herein. We believe that the product is very close to the capturing this year's course in print, and trust readers will enjoy reading the always candid and often provocative remarks from the audience. The price paid for inclusion of the discussion transcriptions was a delay in publication. Each author was allowed to edit his/her discussion section as well as the final version of the chapters prior to publication. The changes are mainly for grammar, and we tried, when possible, not to alter the conversational style of these interchanges.
Book Synopsis Red Blood Cell Substitutes by : Alan Rudolph
Download or read book Red Blood Cell Substitutes written by Alan Rudolph and published by CRC Press. This book was released on 1997-09-05 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents an up-to-date treatment of research strategies, clinical and commercial developments, and regulatory and economic issues pertaining to the formulation of effective and safe red blood cell substitutes. The text examines regulatory and socioeconomic aspects of blood substitute products, and global tranfusion practices from the perspective of
Book Synopsis Hemoglobin-Based Oxygen Carriers as Red Cell Substitutes and Oxygen Therapeutics by : Hae Won Kim
Download or read book Hemoglobin-Based Oxygen Carriers as Red Cell Substitutes and Oxygen Therapeutics written by Hae Won Kim and published by Springer Science & Business Media. This book was released on 2013-12-18 with total page 746 pages. Available in PDF, EPUB and Kindle. Book excerpt: Currently, hemoglobin (Hb)-based oxygen carriers (HBOCs) are leading candidates as red blood cell substitutes. In addition, HBOCs are also potential oxygen therapeutics for treatment of patients with critical ischemic conditions due to atherosclerosis, diabetes and other conditions. This book will provide readers a comprehensive review of topics involved in the HBOC development. It focusses on current products and clinical applications as well as on emerging technologies and future prospects.
Book Synopsis Alternatives to Blood Transfusion in Transfusion Medicine by : Alice Maniatis
Download or read book Alternatives to Blood Transfusion in Transfusion Medicine written by Alice Maniatis and published by John Wiley & Sons. This book was released on 2011-07-05 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt: Meeting the needs of patients while minimizing blood transfusions requires special expertise, precise monitoring and innovative techniques. This cutting-edge resource covers all the important clinical aspects of transfusion medicine in diverse clinical settings, with a special emphasis on alternatives to transfusion. Edited by a multidisciplinary team consisting of a transfusion specialist, an anesthesiologist and an intensive care specialist this book is endorsed by the Network for Advancement of Transfusion Alternatives. The contributors review the appropriate use of fluids and of blood products, and describe the latest treatment options available to decrease the need for allogeneic blood products including: Argon beam Cell saver Harmonic scalpel Normovolemic haemodilution Synthetic erythropoietin Antifibrinolytics Recombinant factor VIIa Advanced monitoring of hemostasis Intravenous iron The new edition is a key reference source for all those involved in the practice of blood management and conservation.
Book Synopsis Artificial Oxygen Carrier by : K. Kobayashi
Download or read book Artificial Oxygen Carrier written by K. Kobayashi and published by Springer Science & Business Media. This book was released on 2005 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: While a reliable supply of donated blood is vital in modern medicine, it remains the case that blood transfusion comes with its own problems, such as infectious diseases, immunological adverse reactions, and difficulties with long-term storage and transportation of blood components. With a view to solving these problems, developing a suitable blood substitute has been a major goal for decades. Artificial Oxygen Carrier: Its Front Line is a compilation of reports on the concepts behind artificial oxygen carriers, as well as the new discoveries in the field that were presented during the 13th Keio International Symposium for Life Science and Medicine. This volume describes valuable topics, including artificial red blood cells, modified haemoglobin, perfluorocarbons, and haemoglobin vesicles. It explains cutting-edge developments in artificial oxygen carrier research and will be a valuable resource to all concerned with the field.
Book Synopsis Chemistry and Biochemistry of Oxygen Therapeutics by : Andrea Mozzarelli
Download or read book Chemistry and Biochemistry of Oxygen Therapeutics written by Andrea Mozzarelli and published by John Wiley & Sons. This book was released on 2011-07-07 with total page 596 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human blood performs many important functions including defence against disease and transport of biomolecules, but perhaps the most important is to carry oxygen – the fundamental biochemical fuel - and other blood gases around the cardiovascular system. Traditional therapies for the impairment of this function, or the rapid replacement of lost blood, have centred around blood transfusions. However scientists are developing chemicals (oxygen therapeutics, or “blood substitutes”) which have the same oxygen-carrying capability as blood and can be used as replacements for blood transfusion or to treat diseases where oxygen transport is impaired. Chemistry and Biochemistry of Oxygen Therapeutics: From Transfusion to Artificial Blood links the underlying biochemical principles of the field with chemical and biotechnological innovations and pre-clinical development. The first part of the book deals with the chemistry, biochemistry, physiology and toxicity of oxygen, including chapters on hemoglobin reactivity and regulation; the major cellular and physiological control mechanisms of blood flow and oxygen delivery; hemoglobin and myoglobin; nitric oxide and oxygen; and the role of reactive oxygen and nitrogen species in ischemia/reperfusion Injury. The book then discusses medical needs for oxygen supply, including acute traumatic hemorrhage and anemia; diagnosis and treatment of haemorrhages in "non-surgical" patients; management of perioperative bleeding; oxygenation in the preterm neonate; ischemia normobaric and hyperbaric oxygen therapy for ischemic stroke and other neurological conditions; and transfusion therapy in β thalassemia and sickle cell disease Finally “old”and new strategies for oxygen supply are described. These include the political, administrative and logistic issues surrounding transfusion; conscientious objection in patient blood management; causes and consequences of red cell incompatibility; biochemistry of red blood cell storage; proteomic investigations on stored red blood cells; red blood cells from stem cells; the universal red blood cell; allosteric effectors of hemoglobin; hemoglobin-based oxygen carriers; oxygen delivery by natural and artificial oxygen carriers; cross-linked and polymerized hemoglobins as potential blood substitutes; design of novel pegylated hemoglobins as oxygen carrying plasma expanders; hb octamers by introduction of surface cysteines; hemoglobin-vesicles as a cellular type hemoglobin-based oxygen carrier; animal models and oxidative biomarkers to evaluate pre-clinical safety of extracellular hemoglobins; and academia – industry collaboration in blood substitute development. Chemistry and Biochemistry of Oxygen Therapeutics: From Transfusion to Artificial Blood is an essential reference for clinicians, haematologists, medicinal chemists, biochemists, molecular biologists, biotechnologists and blood substitute researchers.
Book Synopsis Blood Substitutes by : Robert M. Winslow
Download or read book Blood Substitutes written by Robert M. Winslow and published by Academic Press. This book was released on 2006 with total page 548 pages. Available in PDF, EPUB and Kindle. Book excerpt: Blood substitutes are solutions designed for use in patients who need blood transfusions, but for whom whole blood is not available, or is not safe. This interest has intensified in the wake of the AIDS and hepatitis C epidemics. Blood Substitutes describes the rationale, current approaches, clinical efficacy, and design issues for all blood substitutes now in clinical trials. The many summary diagrams and tables help make the book accessible to readers such as surgeons and blood bankers, who have less technical expertise than the biochemists and hematologists who are designing and testing blood substitutes. * Includes chapters necessary to the understanding of blood substitutes, including history, toxicity, physiology, and clinical applications * Presents detailed descriptions of the various products that have been developed and have advanced to clinical trials, and some that are in earlier states of development
Book Synopsis Blood Substitutes and Oxygen Biotherapeutics by : Henry Liu
Download or read book Blood Substitutes and Oxygen Biotherapeutics written by Henry Liu and published by Springer Nature. This book was released on 2022-08-08 with total page 441 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book functions as a comprehensive and authoritative reference book in blood transfusion and blood substitutes. It is a collection of the latest developments and the newest investigations, and individual chapters are written by world experts in the arena. The book begins with a historical review on the practice of transfusions as well as the components and physiology of blood. The following chapters cover various topics, including platelet substitutes, hemoglobin-based oxygen carriers, perfluorocarbon based oxygen carriers, and safety issues related to artificial hemoglobin. All chapters provide a bulleted highlights list to facilitate readers in mastering the main points of each individual chapter. Blood Substitutes and Oxygen Biotherapeutics is an invaluable reference book for perioperative care providers, hematologists, anesthesiologists, surgeons, obstetricians and gynecologists.
Book Synopsis Blood Substitutes by : Thomas Ming Swi Chang
Download or read book Blood Substitutes written by Thomas Ming Swi Chang and published by . This book was released on 1997 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Blood Substitutes by : Robert M. Winslow
Download or read book Blood Substitutes written by Robert M. Winslow and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains a collection of essays by selected authors who are active in the field of blood substitutes research or closely allied disciplines. These essays were delivered as lectures by the authors at the second annual "Current Issues in Blood Substitute Research and Development - 1995" course sponsored jointly by the Departments of Medicine and Bioengineer ing, University of California, San Diego, the National Institutes of Health (NHLBI), and the U.S. Army on March 30, 31, and April 1, 1995 in San Diego. This course had three goals: to present fundaniental discussions of scientific issues critical to further development of artificial oxygen carriers, to provide academicians a forum to discuss their current research, and to provide the companies involved in developing products the opportunity to update the audience on their progress. The organization owes much to the solicited comments of the attendees of the 1994 course. We would like especially to thank the U.S. Army, particularly through the efforts of COL John Hess, who provided significant funding to make publication of this volume possible. In addition, a number of the participating companies provided additional financial support to offset the costs of the course. These include Alliance Pharmaceutical Corp., Hemosol, Nippon Oil and Fat, Northfield Laboratories, and Ortho Biotech.
Book Synopsis Red Blood Cell Substitutes by : Alan Rudolph
Download or read book Red Blood Cell Substitutes written by Alan Rudolph and published by CRC Press. This book was released on 1997-09-05 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents an up-to-date treatment of research strategies, clinical and commercial developments, and regulatory and economic issues pertaining to the formulation of effective and safe red blood cell substitutes. The text examines regulatory and socioeconomic aspects of blood substitute products, and global tranfusion practices from the perspective of blood banks and the US Food and Drug Administrations. It also includes the mechanisms of action and consequences of blood substitute administration.
Book Synopsis Nanotechnology for Hematology, Blood Transfusion, and Artificial Blood by : Adil Denizli
Download or read book Nanotechnology for Hematology, Blood Transfusion, and Artificial Blood written by Adil Denizli and published by Elsevier. This book was released on 2021-09-28 with total page 495 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanotechnology for Hematology, Blood Transfusion, and Artificial Blood outlines the fundamental design concepts and emerging applications of nanotechnology in hematology, blood transfusion and artificial blood. This book is an important reference source for materials scientists, engineers and biomedical scientists who are looking to increase their understanding of how nanotechnology can lead to more efficient blood treatments. Sections focus on how nanotechnology could offer new routes to address challenging and pressing issues facing rare blood diseases and disorders and how nanomaterials can be used as artificial cell-like systems (compartmentalized biomimetic nanocontainers), which are especially useful in drug delivery. For artificial blood, the nanotechnological approach can fabricate artificial red blood cells, platelet substitutes, and white blood cell substitutes with their inherent enzyme and other supportive systems. In addition, nanomaterials can promote blood vessel growth and reserve red blood cells at a positive temperature. Provides information on how nanotechnology can be used to create more efficient solutions for blood transfusions and hematology treatments Explores the major nanomaterial types that are used for these treatments Assesses the major challenges of using nanomaterials hematology
Book Synopsis Essentials of Blood Product Management in Anesthesia Practice by : Corey S. Scher
Download or read book Essentials of Blood Product Management in Anesthesia Practice written by Corey S. Scher and published by Springer Nature. This book was released on 2021-03-12 with total page 469 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive book is written to inform and improve outcomes of patients in need of blood management during surgical procedures. Information is presented in an accessible format, allowing for immediate use in clinical practice. Beginning with an overview of the history of blood transfusions, early chapters present the foundational information needed to comprehend information in later chapters. Nuanced procedures, drugs, and techniques are covered, including new biologicals to assist clotting and blood substitutes. Further discussions focus on potential complications seen in blood transfusions, such as diseases of the coagulation system, pathogen transmissions, and acute lung injuries. Chapters also examine the complexities of treating specific demographics, of which include the geriatric patient and patients suffering from substance abuse. Essentials of Blood Product Management in Anesthesia Practice is an invaluable guide for anesthesiologists, surgeons, trauma physicians, and solid organ transplant providers.
