Blood Filtration And Blood Cell Deformability

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Blood Filtration and Blood Cell Deformability

Author : John A. Dormandy
Publisher : Springer Science & Business Media
ISBN 13 : 940095008X
Total Pages : 103 pages
Book Rating : 4.4/5 (9 download)

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Book Synopsis Blood Filtration and Blood Cell Deformability by : John A. Dormandy

Download or read book Blood Filtration and Blood Cell Deformability written by John A. Dormandy and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 103 pages. Available in PDF, EPUB and Kindle. Book excerpt: H. J. Meiselman From the theoretical studies of Dr. Skalak, it is clear that white cells can significantly influence the pressure-time profile of a red cell/white cell suspen sion, and that the presence of even a small amount of relatively rigid white cells can have a profound effect on the filtration pressure during the latter portion of a filtration experiment. Conversely, white cell effects, regardless of their relative rigidity, are shown to have only minimal effects during the very early (i. e. , 0-2 seconds) phases of the filtration process. Dr. Chien's experimental data support these theoretical studies, in that white cells of different mechan ical properties exhibit different pressure-time curves; pressure-time data for mixtures of leucocytes show shapes which can be predicted from the behavior of relatively homogeneous cell populations. The insensitivity of the very early portions of the filtration process to white cells is again reflected in the calculations made by Dr. Hanss. Using the nominal dilutions, white cell concentrations and the total volume of filtered cell suspension, he indicates that usually less than 1 pore out of 100 is liable to blockage by white cells. He thus concludes that, at the 1% accuracy level, initial filtration data should not be affected by mechanical pore blockage by white cells. Experimental studies by Dr. Lowe and Dr. Stuart question the WBC insensitivity of the early portion of the filtration process. Using a constant flow system, Dr.

Red Cell Membrane Transport in Health and Disease

Author : Ingolf Bernhardt
Publisher : Springer Science & Business Media
ISBN 13 : 3662051818
Total Pages : 761 pages
Book Rating : 4.6/5 (62 download)

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Book Synopsis Red Cell Membrane Transport in Health and Disease by : Ingolf Bernhardt

Download or read book Red Cell Membrane Transport in Health and Disease written by Ingolf Bernhardt and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 761 pages. Available in PDF, EPUB and Kindle. Book excerpt: 51 worldwide leading experts in the field of erythrocyte research contributed to this first book on transport processes in red blood cells. It explains the latest findings on the basis of well-established principles, in an accessibly structured and carefully organized compilation.

The Red Cell Membrane

Author : Robert I. Weed
Publisher : Saunders
ISBN 13 :
Total Pages : 200 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Red Cell Membrane by : Robert I. Weed

Download or read book The Red Cell Membrane written by Robert I. Weed and published by Saunders. This book was released on 1971 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Applied Physiology in Intensive Care Medicine

Author : Michael R. Pinsky
Publisher : Springer Science & Business Media
ISBN 13 : 3540373632
Total Pages : 367 pages
Book Rating : 4.5/5 (43 download)

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Book Synopsis Applied Physiology in Intensive Care Medicine by : Michael R. Pinsky

Download or read book Applied Physiology in Intensive Care Medicine written by Michael R. Pinsky and published by Springer Science & Business Media. This book was released on 2007-05-19 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: Te practice of intensive care medicine is at the very forefront of titration of treatment andmonitoringresponse. Te substrateofthiscareisthe criticallyill patientwho,by defnition, is at the limits of his or her physiologic reserve. Such patients need immediate, aggressive but balanced life-altering interventions to minimize the detrimental aspects of acute illness and hasten recovery. Treatmentdecisionsandresponsetotherapyareusually assessed by measures of physiologic function, such as assessed by cardio-respiratory monitoring. However, how one uses such information is ofen unclear and rarely supported by prospective clinical trials. In reality, the bedside clinician is forced to rely primarily on physiologic principles in determining the best treatments and response to therapy. However, the physiologic foundation present in practicing physicians is uneven and occasionally supported more by habit or prior training than science. A series of short papers published in Intensive Care Medicine since 2002 under the heading Physiologic Notes attempts to capture the essence of the physiologic perspectives that underpin both our understanding of disease and response to therapy. Tis present volume combines the complete list of these Physiologic Notes up until July 2006 with the ass o cia t ed r e vie w a r tic les o v er t h e s a m e in t er val t ha t a ls o addr ess e d t hes e cen tral issues.

Encyclopedia of Malaria

Author :
Publisher : Springer
ISBN 13 : 9781461483250
Total Pages : 0 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Encyclopedia of Malaria by :

Download or read book Encyclopedia of Malaria written by and published by Springer. This book was released on 2018-07-12 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Encyclopedia of Malaria represents a vast databank of information about the study of malaria. It provides an overview of the historical, rapid and significant developments that have occurred in malaria research, including the 2002 genome sequencing of Plasmodium falciparum and its mosquito vector, Anopheles gambiae. This work provides a concise source of up-to-date research findings in the form of definitions and essays and present comprehensive coverage of topics from history to findings to diagnosis and treatment, written by recognized malaria researchers with practical experience. It appeals to a diverse audience, including malaria researchers, teachers, investigators and public health professionals.

Clinical Aspects of Blood Viscosity and Cell Deformability

Author : G. D. O. Lowe
Publisher : Springer Science & Business Media
ISBN 13 : 1447131053
Total Pages : 268 pages
Book Rating : 4.4/5 (471 download)

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Book Synopsis Clinical Aspects of Blood Viscosity and Cell Deformability by : G. D. O. Lowe

Download or read book Clinical Aspects of Blood Viscosity and Cell Deformability written by G. D. O. Lowe and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: After many years of relative neglect, the importance of study of factors governing blood flow has at last achieved recognition; in this volume are documented many of the techniques, and the basic scientific and clinical observations, which have helped to open up understanding of this highly important aspect of human physiology and pathology in recent years. The text is logically divided into five sections beginning with blood cell deformability, then moving on to theoretical consideration of blood rheology, followed by accounts of the interrelationships between rheology, blood flow and vascular occlusion. The final two sections deal with blood rheology in clinical practice and therapeutic aspects of the study of blood flow. As regards blood cell deformability (Section A), the basic problem is set out by Kiesewetter and colleagues in the first paragraph of chapter 1 (p. 3), in which they point out that whereas human erythrocytes at rest have a diameter of approxi mately 7. 5 /-tm, nutritive capillaries have diameters ranging from 3-5 /-tm, and chapters in section A give an account of the ways in which the red cell can undergo deformation to permit capillary perfusion and the maintenance of the microcirculation.

Red Blood Cell Aggregation

Author : Oguz Baskurt
Publisher : CRC Press
ISBN 13 : 1439841802
Total Pages : 326 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Red Blood Cell Aggregation by : Oguz Baskurt

Download or read book Red Blood Cell Aggregation written by Oguz Baskurt and published by CRC Press. This book was released on 2011-09-28 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: Red blood cells in humans—and most other mammals—have a tendency to form aggregates with a characteristic face-to-face morphology, similar to a stack of coins. Known as rouleaux, these aggregates are a normally occurring phenomenon and have a major impact on blood rheology. What is the underlying mechanism that produces this pattern? Does this really happen in blood circulation? And do these rouleaux formations have a useful function? The first book to offer a comprehensive review of the subject, Red Blood Cell Aggregation tackles these and other questions related to red blood cell (RBC) aggregates. The book covers basic, clinical, and physiological aspects of this important biophysical phenomenon and integrates these areas with concepts in bioengineering. It brings together state-of-the-art research on the determinants, mechanisms, and measurement and effects of RBC aggregation as well as on variations and comparative aspects. After an introductory overview, the book outlines factors and conditions that affect RBC aggregation. It presents the two hypotheses—the bridging model and the depletion model—that provide potential mechanisms for the adhesive forces that lead to the regular packing of the cells in rouleaux formations. The book also reviews the methods used to quantify RBC aggregation in vitro, focusing on their importance in clinical practice. Chapters discuss the effect of RBC aggregation on the in vitro rheology of blood as well as on tube flow. The book also looks at what happens in the circulation when red blood cells aggregate and examines variations due to physiological and pathophysiological challenges. The concluding chapter explores the formation of red blood cell aggregates in other mammals. Written by leading researchers in the field, this is an invaluable resource for basic science, medical, and clinical researchers; graduate students; and clinicians interested in mammalian red blood cells.

Transfusion Medicine and Scientific Developments

Author : A.W.M.M. Koopman-van Gemert
Publisher : BoD – Books on Demand
ISBN 13 : 9535133195
Total Pages : 130 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Transfusion Medicine and Scientific Developments by : A.W.M.M. Koopman-van Gemert

Download or read book Transfusion Medicine and Scientific Developments written by A.W.M.M. Koopman-van Gemert and published by BoD – Books on Demand. This book was released on 2017-07-05 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt: Transfusion Medicine and Scientific Developments focuses on unknown aspects of blood cells and transfusion practice. Blood transfusion medicine has become a sophisticated and specialized field of medicine. Some aspects will be discussed in this book. The book has been divided into three sections. The first section includes chapters describing the immunological and coagulation-assisting functions of red blood cells and methods to measure their life span. The second section discusses the role of platelets in inflammatory processes. The third section reviews functional dose of RBC transfusions and transfusion practice in various clinical settings.

Red Cell Membranes

Author : Stephen Byron Shohet
Publisher :
ISBN 13 :
Total Pages : 352 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Red Cell Membranes by : Stephen Byron Shohet

Download or read book Red Cell Membranes written by Stephen Byron Shohet and published by . This book was released on 1988 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Red Cell Deformability and Filterability

Author : John A. Dormandy
Publisher : Springer Science & Business Media
ISBN 13 : 9400967268
Total Pages : 233 pages
Book Rating : 4.4/5 (9 download)

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Book Synopsis Red Cell Deformability and Filterability by : John A. Dormandy

Download or read book Red Cell Deformability and Filterability written by John A. Dormandy and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is an edited verbatim account of the proceedings of the Second London Workshop on Red Cell Filtration and Deformability, organised jointly by the Royal Society of Medicine and the Groupe de Travail sur la Filtration Erythrocytaire. The first such London Workshop was held on the occasion of the Second European Conference on Clinical Haemorheology in 1981 and its con clusions were published in an abbreviated form. The interest in blood filtration as a technique for assessing red cell deformability has continued to increase and there are now several hundred centres around the world using some form of filtration. It was, therefore, felt that the informal detailed discussions held by a small invited group of experts from many countries would be of more general interest and therefore worth publishing. This has been made possible by the continued interest and generous support of Hoechst. Spontaneous open discussion rather than formal presentations has been the hallmark of these workshops, with precirculation of all scientific data to the participants. We have attempted to preserve this flavour in editing the transcript of the proceedings. This, together with our anxiety for rapid publication, may have resulted in a less than finely polished text which may contain some in accuracies. The topics discussed were loosely structured into eight sessions, outlined in the accompanying programme.

Handbook of Hemorheology and Hemodynamics

Author : O.K. Baskurt
Publisher : IOS Press
ISBN 13 : 1607502631
Total Pages : 468 pages
Book Rating : 4.6/5 (75 download)

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Book Synopsis Handbook of Hemorheology and Hemodynamics by : O.K. Baskurt

Download or read book Handbook of Hemorheology and Hemodynamics written by O.K. Baskurt and published by IOS Press. This book was released on 2007-10-03 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: This publication primarily focuses on the macro- and micro-rheological behavior of blood and its formed elements, on interactions between the formed elements and blood vessel walls, and on the microvascular aspects of hemodynamics. Since many aspects of hemorheology and hemodynamics are affected by disease or clinical states, these effects are discussed as are hyperviscosity syndromes, therapy for disturbed blood rheology, and methods in hemorheology and hemodynamics. Sections of the Handbook include History of Hemorheology; Hemorheology, covering basic aspects, blood composition, blood rheology, cell mechanics, pathophysiology, methods and comparative studies; Hemodynamics, covering basic principles, microcirculation, in vivo effects, endothelium and methods; and Clinical Aspects of Hemorheology, covering hyperviscosity, clinical significance and treatment. The goal is to foster greater interchange between workers in the fields so as to promote collaborative efforts and, hopefully, improved health. In selecting topics for this handbook the editors have attempted to provide a general overview of both basic science and clinical hemorheology and hemodynamics. Hemorheology and hemodynamics are closely related, the former dealing with all aspects of the flow and interactions of the individual blood cells mostly studied in vitro, the latter with the in vivo relationships among vessel architecture, driving pressure, flow rate and shear stress. The linkage between the in vitro and in vivo research described in the book will be of interest to both basic science and clinical investigators. The editors of the handbook have each been active in the fields of bio- and hemorheology for many years, and have published extensively. They have successfully achieved their objective to publish a well-written and well-edited handbook that will be valuable for researchers and students in the field.

Clinical Benefits of Leukodepleted Blood Products

Author : Joseph Sweeney
Publisher : Springer Science & Business Media
ISBN 13 : 3662265389
Total Pages : 202 pages
Book Rating : 4.6/5 (622 download)

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Book Synopsis Clinical Benefits of Leukodepleted Blood Products by : Joseph Sweeney

Download or read book Clinical Benefits of Leukodepleted Blood Products written by Joseph Sweeney and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: Joseph Sweeney, Andrew Heaton he presence of allogeneic leukocytes in blood products received little T attention until the mid-1950s when these "passenger" cells were im plicated in the etiology of febrile transfusion reactions, and early strate gies based on centrifugation were developed to effect their removal. In recent decades and, particularly in the past five years, there has been an accumulation of literature implicating leukocytes in a wide variety of undesirable reactions to blood transfusion. White cells are the least numerous of the cellular elements in blood and ratios of white cells to platelets and white cells to red cells are ap proximately 1:15 to 1:1000 respectively. This ratio is maintained in whole blood, but may be altered slightly in the process of component prepara tion. Any production or processing step which intentionally decreases this ratio will result in a product which can be described as white cell depleted. It has, however, become more common to define the outcome as a residual white cell content, rather than a decrease in cellular ratios, although the latter makes more sense on theoretical grounds, since deple tion of white cells needs to be put in the context of any unintentional loss of red cells or platelets. The end result of this intentional processing step, therefore, is generally expressed as the residual absolute number of white cells or as the degree of difference in white cell content, the latter expressed as either a percentage change or as a logarithmic reduction.

Clinical Blood Rheology

Author : Gordon D.O. Lowe
Publisher : CRC Press
ISBN 13 : 0429523300
Total Pages : 254 pages
Book Rating : 4.4/5 (295 download)

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Book Synopsis Clinical Blood Rheology by : Gordon D.O. Lowe

Download or read book Clinical Blood Rheology written by Gordon D.O. Lowe and published by CRC Press. This book was released on 2019-06-04 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: Published in 1988: Study of blood flow properties (rheology) has attracted growing interest from clinicians in recent years. A United Kingdom meeting and a European meeting in 1979 resulted in previous publications summarizing the literature up to that time.

Living Blood Cells and Their Ultrastructure

Author : Marcel Bessis
Publisher : Springer Verlag
ISBN 13 : 9780387059815
Total Pages : 767 pages
Book Rating : 4.0/5 (598 download)

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Book Synopsis Living Blood Cells and Their Ultrastructure by : Marcel Bessis

Download or read book Living Blood Cells and Their Ultrastructure written by Marcel Bessis and published by Springer Verlag. This book was released on 1973 with total page 767 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Bioprocessing for Cell-Based Therapies

Author : Che J. Connon
Publisher : John Wiley & Sons
ISBN 13 : 1118743415
Total Pages : 276 pages
Book Rating : 4.1/5 (187 download)

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Book Synopsis Bioprocessing for Cell-Based Therapies by : Che J. Connon

Download or read book Bioprocessing for Cell-Based Therapies written by Che J. Connon and published by John Wiley & Sons. This book was released on 2017-02-06 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: With contributions from leading, international academics and industrial practitioners, Bioprocessing for Cell-Based Therapies explores the very latest techniques and guidelines in bioprocess production to meet safety, regulatory and ethical requirements, for the production of therapeutic cells, including stem cells. An authoritative, cutting-edge handbook on bioprocessing for the production of therapeutic cells with extensive illustrations in full colour throughout An authoritative, cutting-edge handbook on bioprocessing for the production of therapeutic cells with extensive illustrations in full colour throughout In depth discussion of the application of cell therapy including methods used in the delivery of cells to the patient Includes contributions from experts in both academia and industry, combining a practical approach with cutting edge research The only handbook currently available to provide a state of the art guide to Bioprocessing covering the complete range of cell-based therapies, from experts in academia and industry

Microcirculation

Author : Ronald F. Tuma
Publisher : Academic Press
ISBN 13 : 0080569935
Total Pages : 999 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Microcirculation by : Ronald F. Tuma

Download or read book Microcirculation written by Ronald F. Tuma and published by Academic Press. This book was released on 2011-04-28 with total page 999 pages. Available in PDF, EPUB and Kindle. Book excerpt: This reference is a volume in the Handbook of Physiology, co-published with The American Physiological Society. Growth in knowledge about the microcirculation has been explosive with the field becoming fragmented into numerous subdisciplines and subspecialties. This volume pulls all of the critical information into one volume. - Meticulously edited and reviewed. Benefit: Provides investigators a unique tool to explore the significance of their findings in the context of other aspects of the microcirculation. In this way, the updated edition has a direct role in helping to develop new pathways of research and scholarship - Highlights the explosive growth in knowledge about the microcirculation including the biology of nitric oxide synthase (NOS), endothelial cell signaling, angiogenesis, cell adhesion molecules, lymphocyte trafficking, ion channels and receptors, and propagated vasomotor responses. Benefit: Microcirculatory biology has become fragmented into numerous sub-disciplines and subspecialties, and these reference reintegrates the information in one volume

Micro/Nano Devices for Blood Analysis

Author : Rui A. Lima
Publisher : MDPI
ISBN 13 : 3039218247
Total Pages : 174 pages
Book Rating : 4.0/5 (392 download)

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Book Synopsis Micro/Nano Devices for Blood Analysis by : Rui A. Lima

Download or read book Micro/Nano Devices for Blood Analysis written by Rui A. Lima and published by MDPI. This book was released on 2019-12-03 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: The development of micro- and nanodevices for blood analysis is an interdisciplinary subject that demands the integration of several research fields, such as biotechnology, medicine, chemistry, informatics, optics, electronics, mechanics, and micro/nanotechnologies. Over the last few decades, there has been a notably fast development in the miniaturization of mechanical microdevices, later known as microelectromechanical systems (MEMS), which combine electrical and mechanical components at a microscale level. The integration of microflow and optical components in MEMS microdevices, as well as the development of micropumps and microvalves, have promoted the interest of several research fields dealing with fluid flow and transport phenomena happening in microscale devices. Microfluidic systems have many advantages over their macroscale counterparts, offering the ability to work with small sample volumes, providing good manipulation and control of samples, decreasing reaction times, and allowing parallel operations in one single step. As a consequence, microdevices offer great potential for the development of portable and point-of-care diagnostic devices, particularly for blood analysis. Moreover, the recent progress in nanotechnology has contributed to its increasing popularity, and has expanded the areas of application of microfluidic devices, including in the manipulation and analysis of flows on the scale of DNA, proteins, and nanoparticles (nanoflows). In this Special Issue, we invited contributions (original research papers, review articles, and brief communications) that focus on the latest advances and challenges in micro- and nanodevices for diagnostics and blood analysis, micro- and nanofluidics, technologies for flow visualization, MEMS, biochips, and lab-on-a-chip devices and their application to research and industry. We hope to provide an opportunity to the engineering and biomedical community to exchange knowledge and information and to bring together researchers who are interested in the general field of MEMS and micro/nanofluidics and, especially, in its applications to biomedical areas.