Regulation of Tissue Oxygenation, Second Edition

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Publisher : Biota Publishing
ISBN 13 : 1615047212
Total Pages : 117 pages
Book Rating : 4.6/5 (15 download)

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Book Synopsis Regulation of Tissue Oxygenation, Second Edition by : Roland N. Pittman

Download or read book Regulation of Tissue Oxygenation, Second Edition written by Roland N. Pittman and published by Biota Publishing. This book was released on 2016-08-18 with total page 117 pages. Available in PDF, EPUB and Kindle. Book excerpt: This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.

Acid-base Balance

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Publisher : Manchester University Press
ISBN 13 : 9780719019821
Total Pages : 172 pages
Book Rating : 4.0/5 (198 download)

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Book Synopsis Acid-base Balance by : R. Hainsworth

Download or read book Acid-base Balance written by R. Hainsworth and published by Manchester University Press. This book was released on 1986 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Capillary Fluid Exchange

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Publisher : Morgan & Claypool Publishers
ISBN 13 : 1615040668
Total Pages : 86 pages
Book Rating : 4.6/5 (15 download)

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Book Synopsis Capillary Fluid Exchange by : Joshua Scallan

Download or read book Capillary Fluid Exchange written by Joshua Scallan and published by Morgan & Claypool Publishers. This book was released on 2010 with total page 86 pages. Available in PDF, EPUB and Kindle. Book excerpt: The partition of fluid between the vascular and interstitial compartments is regulated by forces (hydrostatic and oncotic) operating across the microvascular walls and the surface areas of permeable structures comprising the endothelial barrier to fluid and solute exchange, as well as within the extracellular matrix and lymphatics. In addition to its role in the regulation of vascular volume, transcapillary fluid filtration also allows for continuous turnover of water bathing tissue cells, providing the medium for diffusional flux of oxygen and nutrients required for cellular metabolism and removal of metabolic byproducts. Transendothelial volume flow has also been shown to influence vascular smooth muscle tone in arterioles, hydraulic conductivity in capillaries, and neutrophil transmigration across postcapillary venules, while the flow of this filtrate through the interstitial spaces functions to modify the activities of parenchymal, resident tissue, and metastasizing tumor cells. Likewise, the flow of lymph, which is driven by capillary filtration, is important for the transport of immune and tumor cells, antigen delivery to lymph nodes, and for return of filtered fluid and extravasated proteins to the blood. Given this background, the aims of this treatise are to summarize our current understanding of the factors involved in the regulation of transcapillary fluid movement, how fluid movements across the endothelial barrier and through the interstitium and lymphatic vessels influence cell function and behavior, and the pathophysiology of edema formation. Table of Contents: Fluid Movement Across the Endothelial Barrier / The Interstitium / The Lymphatic Vasculature / Pathophysiology of Edema Formation

Pituitary Adenylate Cyclase-Activating Polypeptide

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Publisher : Springer Science & Business Media
ISBN 13 : 9781402073069
Total Pages : 432 pages
Book Rating : 4.0/5 (73 download)

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Book Synopsis Pituitary Adenylate Cyclase-Activating Polypeptide by : Hubert Vaudry

Download or read book Pituitary Adenylate Cyclase-Activating Polypeptide written by Hubert Vaudry and published by Springer Science & Business Media. This book was released on 2003 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pituitary Adenylate Cyclase-Activating Polypeptide is the first volume to be written on the neuropeptide PACAP. It covers all domains of PACAP from molecular and cellular aspects to physiological activities and promises for new therapeutic strategies. Pituitary Adenylate Cyclase-Activating Polypeptide is the twentieth volume published in the Endocrine Updates book series under the Series Editorship of Shlomo Melmed, MD.

Anatomy & Physiology

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Publisher :
ISBN 13 : 9781955101158
Total Pages : pages
Book Rating : 4.1/5 (11 download)

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Book Synopsis Anatomy & Physiology by : Lindsay Biga

Download or read book Anatomy & Physiology written by Lindsay Biga and published by . This book was released on 2019-09-26 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: A version of the OpenStax text

Mechanisms of Vascular Disease

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Publisher : University of Adelaide Press
ISBN 13 : 1922064009
Total Pages : 589 pages
Book Rating : 4.9/5 (22 download)

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Book Synopsis Mechanisms of Vascular Disease by : Robert Fitridge

Download or read book Mechanisms of Vascular Disease written by Robert Fitridge and published by University of Adelaide Press. This book was released on 2011 with total page 589 pages. Available in PDF, EPUB and Kindle. Book excerpt: New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.

Pathological Physiology of Internal Diseases

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Publisher :
ISBN 13 :
Total Pages : 832 pages
Book Rating : 4.:/5 (38 download)

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Book Synopsis Pathological Physiology of Internal Diseases by : Albion Walter Hewlett

Download or read book Pathological Physiology of Internal Diseases written by Albion Walter Hewlett and published by . This book was released on 1928 with total page 832 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Regulation of Coronary Blood Flow

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Publisher : Springer Science & Business Media
ISBN 13 : 4431683674
Total Pages : 330 pages
Book Rating : 4.4/5 (316 download)

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Book Synopsis Regulation of Coronary Blood Flow by : Michitoshi Inoue

Download or read book Regulation of Coronary Blood Flow written by Michitoshi Inoue and published by Springer Science & Business Media. This book was released on 2013-11-09 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research centering on blood flow in the heart continues to hold an important position, especially since a better understanding of the subject may help reduce the incidence of coronary arterial disease and heart attacks. This book summarizes recent advances in the field; it is the product of fruitful cooperation among international scientists who met in Japan in May, 1990 to discuss the regulation of coronary blood flow.

A Manual of General Pathology

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Publisher :
ISBN 13 :
Total Pages : 574 pages
Book Rating : 4.A/5 ( download)

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Book Synopsis A Manual of General Pathology by : Joseph Frank Payne

Download or read book A Manual of General Pathology written by Joseph Frank Payne and published by . This book was released on 1888 with total page 574 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Transactions of the First-fifty-ninth Annual Meeting ...

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Publisher :
ISBN 13 :
Total Pages : 338 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Transactions of the First-fifty-ninth Annual Meeting ... by : Ohio state medical society

Download or read book Transactions of the First-fifty-ninth Annual Meeting ... written by Ohio state medical society and published by . This book was released on 1853 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Perioperative Hemodynamic Monitoring and Goal Directed Therapy

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Publisher : Cambridge University Press
ISBN 13 : 1316061442
Total Pages : 301 pages
Book Rating : 4.3/5 (16 download)

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Book Synopsis Perioperative Hemodynamic Monitoring and Goal Directed Therapy by : Maxime Cannesson

Download or read book Perioperative Hemodynamic Monitoring and Goal Directed Therapy written by Maxime Cannesson and published by Cambridge University Press. This book was released on 2014-09-04 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique book provides clinicians and administrators with a comprehensive understanding of perioperative hemodynamic monitoring and goal directed therapy, emphasizing practical guidance for implementation at the bedside. Successful hemodynamic monitoring and goal directed therapy require a wide range of skills. This book will enable readers to: • Detail the rationale for using perioperative hemodynamic monitoring systems and for applying goal directed therapy protocols at the bedside • Understand the physiological concepts underlying perioperative goal directed therapy for hemodynamic management • Evaluate hemodynamic monitoring systems in clinical practice • Learn about new techniques for achieving goal directed therapy • Apply goal directed therapy protocols in the perioperative environment (including emergency departments, operating rooms and intensive care units) • Demonstrate clinical utility of GDT and hemodynamic optimization using case presentations. Illustrated with diagrams and case examples, this is an important resource for anesthesiologists, emergency physicians, intensivists and pneumonologists as well as nurses and administrative officers.

Crafting Immunity

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Publisher : Ashgate Publishing, Ltd.
ISBN 13 : 9780754657590
Total Pages : 326 pages
Book Rating : 4.6/5 (575 download)

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Book Synopsis Crafting Immunity by : Kenton Kroker

Download or read book Crafting Immunity written by Kenton Kroker and published by Ashgate Publishing, Ltd.. This book was released on 2008 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunity is as old as illness itself, yet historians have only just begun to take up the challenge of reconstructing the modern transformation of attempts to protect against disease. Crafting Immunity assembles in one volume the most recent efforts of an international group of scholars to place the diverse practices of immunity in their historical contexts. It is this diversity that provides the book with its greatest source of strength. Collectively, the papers in this volume suggest that it was the craft-like, small-scale, and local conditions of clinical medicine that turned the immunity of individuals and populations into biomedical objects. That is to say, the modern conception of immunity was at least as much the product of the work of healing as it was the systematic result of discoveries about the immune system.Working outside the narrow confines of laboratory histories, Crafting Immunity is the first attempt to set the problems of immunity into a variety of social, technological, institutional and intellectual contexts. It will appeal not only to historians and sociologists of health, but also to social and cultural historians interested in the biomedical creation of modern health regimens.

Journal of the American Medical Association

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Publisher :
ISBN 13 :
Total Pages : 1214 pages
Book Rating : 4.E/5 ( download)

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Book Synopsis Journal of the American Medical Association by : American Medical Association

Download or read book Journal of the American Medical Association written by American Medical Association and published by . This book was released on 1915 with total page 1214 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Blood Brain Barrier (BBB)

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Publisher : Springer
ISBN 13 : 3662437872
Total Pages : 169 pages
Book Rating : 4.6/5 (624 download)

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Book Synopsis The Blood Brain Barrier (BBB) by : Gert Fricker

Download or read book The Blood Brain Barrier (BBB) written by Gert Fricker and published by Springer. This book was released on 2014-10-24 with total page 169 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging) drug targets, structural biology, drugability of targets, drug design approaches, chemogenomics, synthetic chemistry including combinatorial methods, bioorganic chemistry, natural compounds, high-throughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactions on the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. In general, special volumes are edited by well known guest editors.

A Dictionary of Practical Medicine: Comprising General Pathology ...

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Publisher :
ISBN 13 :
Total Pages : 560 pages
Book Rating : 4.A/5 ( download)

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Book Synopsis A Dictionary of Practical Medicine: Comprising General Pathology ... by : James Copland

Download or read book A Dictionary of Practical Medicine: Comprising General Pathology ... written by James Copland and published by . This book was released on 1845 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Lectures on Some of the Applications of Chemistry and Mechanics to Pathology and Therapeutics

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Publisher :
ISBN 13 :
Total Pages : 372 pages
Book Rating : 4.0/5 (17 download)

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Book Synopsis Lectures on Some of the Applications of Chemistry and Mechanics to Pathology and Therapeutics by : Bence Jones

Download or read book Lectures on Some of the Applications of Chemistry and Mechanics to Pathology and Therapeutics written by Bence Jones and published by . This book was released on 1867 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Dietetic and Hygienic Gazette

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Publisher :
ISBN 13 :
Total Pages : 780 pages
Book Rating : 4.:/5 (31 download)

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Book Synopsis The Dietetic and Hygienic Gazette by :

Download or read book The Dietetic and Hygienic Gazette written by and published by . This book was released on 1904 with total page 780 pages. Available in PDF, EPUB and Kindle. Book excerpt: