Biotransformations In Organic Chemistry A Textbook

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Biotransformations in Organic Chemistry — A Textbook

Author : Kurt Faber
Publisher : Springer Science & Business Media
ISBN 13 : 3642976077
Total Pages : 368 pages
Book Rating : 4.6/5 (429 download)

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Book Synopsis Biotransformations in Organic Chemistry — A Textbook by : Kurt Faber

Download or read book Biotransformations in Organic Chemistry — A Textbook written by Kurt Faber and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of natural catalysts - enzymes - for the transformation of non-natural man-made organic compounds is not at all new: they have been used for more than one hundred years, employed either as whole cells, cell organelles or isolated enzymes [1]. Certainly, the object of most of the early research was totally different from that of the present day. Thus the elucidation of biochemical pathways and enzyme mechanisms was the main reason for research some decades ago. It was mainly during the 1980s that the enormous potential of applying natural catalysts to transform non-natural organic compounds was recognized. What started as a trend in the late 1970s could almost be called a fashion in synthetic organic chemistry in the 1990s. Although the early euphoria during the 'gold rush' in this field seems to have eased somewhat, there is still no limit to be seen for the future development of such methods. As a result of this extensive, recent research, there have been all estimated 8000 papers published on the subject [2-14]. To collate these data as a kind of 'super-review' would clearly be an impossible task and, furthermore, such a hypothetical book would be unpalatable for the non-expert.

Biotransformations in Organic Chemistry

Author : Kurt Faber
Publisher : Springer Science & Business Media
ISBN 13 : 3642173934
Total Pages : 434 pages
Book Rating : 4.6/5 (421 download)

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Book Synopsis Biotransformations in Organic Chemistry by : Kurt Faber

Download or read book Biotransformations in Organic Chemistry written by Kurt Faber and published by Springer Science & Business Media. This book was released on 2011-07-28 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of biocatalysts, employed either as isolated enzymes or whole microbial cells, offers a remarkable arsenal of highly selective transformations for state-of-the-art synthetic organic chemistry. Over the last two decades, this methodology has become an indispensable tool for asymmetric synthesis, not only at the academic level, but also on an industrial scale. This well-established textbook on biocatalysis provides a basis for undergraduate and graduate courses in modern organic chemistry, as well as a condensed introduction into this field. After a basic introduction into the use of biocatalysts—principles of stereoselective transformations, enzyme properties and kinetics—the different types of reactions are explained according to the 'reaction principle', such as hydrolysis, reduction, oxidation, C–C bond formation, etc. Special techniques, such as the use of enzymes in organic solvents, immobilization techniques and modified or artificial enzymes, are treated in a separate section. A final chapter deals with thebasic rules for the safe and practical handling of biocatalysts. In this completely revised 6th edition, emphasis has been given to an improved didactic style including colored graphics in order to facilitate a deeper understanding of the underlying principles. New developments, such as transamination, enzyme promiscuity and applications on industrial scale within the field of 'white biotechnology' are included.

Biotransformations in Organic Chemistry

Author : Kurt Faber
Publisher : Springer Science & Business Media
ISBN 13 : 3642974236
Total Pages : 329 pages
Book Rating : 4.6/5 (429 download)

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Book Synopsis Biotransformations in Organic Chemistry by : Kurt Faber

Download or read book Biotransformations in Organic Chemistry written by Kurt Faber and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of natural catalysts - enzymes - for the transformation of non-natural is not at all new: they have been used for more man-made organic compounds than one hundred years, employed either as whole cells, cell organelles or isolated enzymes [1]. Certainly, the object of most of the early research was totally different from that of the present day. Thus the elucidation of biochemical pathways and enzyme mechanisms was in the foreground of the reasearch some decades ago. It was mainly during the 1980s that the enormous potential of applying natural catalysts to transform non-natural organic compounds was recognized. What started as a trend in the late 1970s could almost be called a fashion in synthetic organic chemistry in the 1990s. Although the early euphoria during the 'gold rush' in this field seems to have eased somewhat, there is still no limit to be seen for the future development of such methods. As a result of this extensive, recent research, there have been an estimated 5000 papers published on the subject [2]. To collate these data as a kind of 'super-review' would clearly be an impossible task and, furthermore, such a hypothetical book would be unpalatable for the non-expert.

Biotransformations In Organic Chemistry, 4E

Author : Faber
Publisher :
ISBN 13 : 9788184890198
Total Pages : 454 pages
Book Rating : 4.8/5 (91 download)

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Book Synopsis Biotransformations In Organic Chemistry, 4E by : Faber

Download or read book Biotransformations In Organic Chemistry, 4E written by Faber and published by . This book was released on 2008-08-01 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt:

An Introduction to Biotransformations in Organic Chemistry

Author : James Ralph Hanson
Publisher : Oxford University Press
ISBN 13 : 9780716745419
Total Pages : 92 pages
Book Rating : 4.7/5 (454 download)

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Book Synopsis An Introduction to Biotransformations in Organic Chemistry by : James Ralph Hanson

Download or read book An Introduction to Biotransformations in Organic Chemistry written by James Ralph Hanson and published by Oxford University Press. This book was released on 1995 with total page 92 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text is part of the Biochemical and Medicinal Chemistry Series Series Editor: John Mann, Professor of Organic Chemistry, University of Reading The aim of this series of short textbooks is to present full accounts of topics which are at the interface of chemistry and biology, from medicinal chemistry to molecular biology. The topics chosen for inclusion are popular subjects for upper-level undergraduate and postgraduate modular courses, and yet they receive inadequate coverage in traditional textbooks of organic chemistry and of biochemistry. Each text in the series provides a concise and up to date introduction to its subject in an attractive format. Biotransformations utilize biological systems to carry out chemical transformations. The use of both isolated enzymes and whole organisms in biotransformations is considered . Such processes are playing an increasingly important role in both the research laboratory and in industry because biotransformations occur under mild, 'environmentally friendly' conditions and they have a selectivity which often differs from that encountered with syntheses using traditional laboratory reagents.This accessible introduction to this growing field provides an up-to-date account of those situations in which biotransformations may present viable alternatives to purely chemical synthetic routes or be used in a complimentary manner to chemical reagents in a multi-step organic synthesis. Dr Hanson's concise introduction tothis burgeoning field covers, in addition to enzymatic and microbial methods, the biotransformation of drugs in humans. It is suitable as a course text for advanced undergraduate and graduate students of chemistry and the biomedical sciences. No previous knowledge of biotransformations is assumed.

有机化学中的生物转换

Author : 费伯
Publisher :
ISBN 13 : 9787506242653
Total Pages : 402 pages
Book Rating : 4.2/5 (426 download)

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Book Synopsis 有机化学中的生物转换 by : 费伯

Download or read book 有机化学中的生物转换 written by 费伯 and published by . This book was released on 1999 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: 作者规范译名:费伯

Practical Biotransformations

Author : Gideon Grogan
Publisher : John Wiley & Sons
ISBN 13 : 1405193670
Total Pages : 352 pages
Book Rating : 4.4/5 (51 download)

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Book Synopsis Practical Biotransformations by : Gideon Grogan

Download or read book Practical Biotransformations written by Gideon Grogan and published by John Wiley & Sons. This book was released on 2009-05-18 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: The development of new asymmetric catalytic methods is of fundamental importance to industrial synthetic chemistry. The demand for optically pure synthetic intermediates and the drive to adopt greener methods of synthesis have stimulated a growing interest in biocatalysis as a selective and environmentally benign synthetic technique. Practical Biotransformations: A Beginner's Guide provides an introduction to microbes and enzymes and demonstrates their practical applications in synthetic organic chemistry. Designed as a laboratory manual, this user-friendly guide discusses standard laboratory techniques, with appropriate advice on aspects of microbial practice and associated safety. Topics covered include: An introduction to equipment in a biotransformations laboratory An overview of biocatalyst sources Maintenance and growth of biocatalysts Example biotransformations using commercially available microbes and enzymes Basic gene cloning and the use of ‘designer’ biocatalysts This book will be a valuable resource for synthetic organic chemists with little or no experience of biochemistry or microbiology. It is the author’s hope that this text will inspire readers to consider biocatalytic methods as real alternatives to traditional synthetic solutions.

Biotransformations

Author : K. Faber
Publisher : Springer Science & Business Media
ISBN 13 : 9783540669494
Total Pages : 238 pages
Book Rating : 4.6/5 (694 download)

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Book Synopsis Biotransformations by : K. Faber

Download or read book Biotransformations written by K. Faber and published by Springer Science & Business Media. This book was released on 2000-02-14 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Whereas the hydrolases such as proteases, esterases and lipases are sufficiently well researched to be applied in every standard laboratory, other types of enzymes are still waiting to be discovered with respect to their applicability in organic-chemistry transformations on a preparative scale. This latter point is stressed here, with the focus on the newcomer-enzymes'which show great synthetic potential.

Biotransfrmtns Prepartv Organic Chemistry

Author : H. G. Davies
Publisher : Academic Press
ISBN 13 : 0080984479
Total Pages : 268 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Biotransfrmtns Prepartv Organic Chemistry by : H. G. Davies

Download or read book Biotransfrmtns Prepartv Organic Chemistry written by H. G. Davies and published by Academic Press. This book was released on 2012-12-02 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is designed for chemists working in an organic chemistry laboratory and for all scientists with an interest in biotransformations. It summarizes the important aspects of work in the burgeoning field of biotransformations, th...[missing text]

Practical Methods for Biocatalysis and Biotransformations 2

Author : John Whittall
Publisher : John Wiley & Sons
ISBN 13 : 1119943418
Total Pages : 392 pages
Book Rating : 4.1/5 (199 download)

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Book Synopsis Practical Methods for Biocatalysis and Biotransformations 2 by : John Whittall

Download or read book Practical Methods for Biocatalysis and Biotransformations 2 written by John Whittall and published by John Wiley & Sons. This book was released on 2012-04-16 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biocatalysts are increasingly used by chemists engaged in fine chemical synthesis within both industry and academia. Today, there exists a huge choice of high-tech enzymes and whole cell biocatalysts, which add enormously to the repertoire of synthetic possibilities. Practical Methods for Biocatalysis and Biotransformations 2 is a "how-to" guide that focuses on the practical applications of enzymes and strains of microorganisms that are readily obtained or derived from culture collections. The sources of starting materials and reagents, hints, tips and safety advice (where appropriate) are given to ensure, as far as possible, that the procedures are reproducible. Comparisons to alternative methodology are given and relevant references to the primary literature are cited. This second volume – which can be used on its own or in combination with the first volume - concentrates on new applications and new enzyme families reported since the first volume. Contents include: introduction to recent developments and future needs in biocatalysts and synthetic biology in industry reductive amination enoate reductases for reduction of electron deficient alkenes industrial carbonyl reduction regio- and stereo- selective hydroxylation oxidation of alcohols selective oxidation industrial hydrolases and related enzymes transferases for alkylation, glycosylation and phosphorylation C-C bond formation and decarboxylation halogenation/dehalogenation/heteroatom oxidation tandem and sequential multi-enzymatic syntheses Practical Methods for Biocatalysis and Biotransformations 2 is an essential collection of biocatalytic methods for chemical synthesis which will find a place on the bookshelves of synthetic organic chemists, pharmaceutical chemists, and process R&D chemists in industry and academia.

Practical Methods for Biocatalysis and Biotransformations 3

Author : John Whittall
Publisher : John Wiley & Sons
ISBN 13 : 1118696298
Total Pages : 320 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Practical Methods for Biocatalysis and Biotransformations 3 by : John Whittall

Download or read book Practical Methods for Biocatalysis and Biotransformations 3 written by John Whittall and published by John Wiley & Sons. This book was released on 2016-02-16 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biocatalysts are increasingly used by chemists engaged in fine chemical synthesis within both industry and academia. Today, there exists a huge choice of high-tech enzymes and whole cell biocatalysts, which add enormously to the repertoire of synthetic possibilities. Practical Methods for Biocatalysis and Biotransformations 3 will be a companion book to Practical Methods for Biocatalysis and Biotransformations (2009) and Practical Methods for Biocatalysis and Biotransformations 2 (2012). Following the successful format of the two volumes, it will be a “how-to” guide focusing on commercially available enzymes and strains of microorganisms that are readily obtained from culture collections. The source of starting materials and reagents, hints, tips and safety advice (where appropriate) will be given to ensure, as far as possible, that the procedures are reproducible. Comparisons to alternative methodology will be given and relevant references to the primary literature will be cited. Contents include: Biotransformation Process Technology Industrial Biooxidation Hydrolase catalysed hydrolysis/synthesis Reduction Oxidation Halogenation Transferase catalysed glycosylation, methylation, etc C-C bond formation Tandem Biocatalytic Reactions Practical Methods for Biocatalysis and Biotransformations, Volume 3 is an essential collection of validated biocatalytic methods which will find a place on the bookshelves of synthetic organic chemists, pharmaceutical chemists, and process R&D chemists in industry and academia.

Progress in the Chemistry of Organic Natural Products 104

Author : A. Douglas Kinghorn
Publisher : Springer
ISBN 13 : 3319456180
Total Pages : 246 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Progress in the Chemistry of Organic Natural Products 104 by : A. Douglas Kinghorn

Download or read book Progress in the Chemistry of Organic Natural Products 104 written by A. Douglas Kinghorn and published by Springer. This book was released on 2017-01-25 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first contribution describes apolar and polar molecular fossils and, in particular biomarkers, along the lines usually followed in organic chemistry textbooks, and points to their bioprecursors when available. Thus, the apolar compounds are divided in linear and branched alkanes followed by alicyclic compounds and aromatic and heterocyclic molecules, and, in particular, the geoporphyrins. The polar molecular fossils contain as functional groups or constituent units ethers, alcohols, phenols, carbonyl groups, flavonoids, quinones, and acids, or are polymers like kerogen, amber, melanin, proteins, or nucleic acids. The final sections discuss the methodology used and the fundamental processes encountered by the biomolecules described, including diagenesis, catagenesis, and metagenesis. The second contribution covers the distribution of phthalides in nature and the findings in the structural diversity, chemical reactivity, biotransformations, syntheses, and bioactivity of natural and semisynthetic phthalides.

Ionic Liquids in Biotransformations and Organocatalysis

Author : Pablo Domínguez de María
Publisher : John Wiley & Sons
ISBN 13 : 1118158741
Total Pages : 356 pages
Book Rating : 4.1/5 (181 download)

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Book Synopsis Ionic Liquids in Biotransformations and Organocatalysis by : Pablo Domínguez de María

Download or read book Ionic Liquids in Biotransformations and Organocatalysis written by Pablo Domínguez de María and published by John Wiley & Sons. This book was released on 2012-02-27 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses the use of ionic liquids in biotransformation and organocatalysis. Its major parts include: an overview of the fundamentals of ionic liquids and their interactions with proteins and enzymes; the use of ILs in biotransformations; non-solvent applications such as additives, membranes, substrate anchoring, and the use of ILs in organocatalysis (from solvents to co-catalysts and new reactivities, as well as non-solvent applications such as anchoring and immobilization).

Fundamentals of Environmental Chemistry, Third Edition

Author : Stanley E. Manahan
Publisher : CRC Press
ISBN 13 : 1420052691
Total Pages : 1266 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Fundamentals of Environmental Chemistry, Third Edition by : Stanley E. Manahan

Download or read book Fundamentals of Environmental Chemistry, Third Edition written by Stanley E. Manahan and published by CRC Press. This book was released on 2011-03-05 with total page 1266 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by an expert, using the same approach that made the previous two editions so successful, Fundamentals of Environmental Chemistry, Third Edition expands the scope of book to include the strongly emerging areas broadly described as sustainability science and technology, including green chemistry and industrial ecology. The new edition includes: Increased emphasis on the applied aspects of environmental chemistry Hot topics such as global warming and biomass energy Integration of green chemistry and sustainability concepts throughout the text More and updated questions and answers, including some that require Internet research Lecturers Pack on CD-ROM with solutions manual, PowerPoint presentations, and chapter figures available upon qualifying course adoptions The book provides a basic course in chemical science, including the fundamentals of organic chemistry and biochemistry. The author uses real-life examples from environmetnal chemistry, green chemistry, and related areas while maintaining brevity and simplicity in his explanation of concepts. Building on this foundation, the book covers environmental chemistry, broadly defined to include sustainability aspects, green chemistry, industrial ecology, and related areas. These chapters are organized around the five environmental spheres, the hydrosphere, atmosphere, geosphere, biosphere, and the anthrosphere. The last two chapters discuss analytical chemistry and its relevance to environmental chemistry. Manahan’s clear, concise, and readable style makes the information accessible, regardless of the readers’ level of chemistry knowledge. He demystifies the material for those who need the basics of chemical science for their trade, profession, or study curriculum, as well as for readers who want to have an understanding of the fundamentals of sustainable chemistry in its crucial role in maintaining a livable planet.

Fundamentals of Sustainable Chemical Science

Author : Stanley E. Manahan
Publisher : CRC Press
ISBN 13 : 1439882088
Total Pages : 392 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Fundamentals of Sustainable Chemical Science by : Stanley E. Manahan

Download or read book Fundamentals of Sustainable Chemical Science written by Stanley E. Manahan and published by CRC Press. This book was released on 2009-03-10 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by Stanley Manahan, Fundamentals of Sustainable Chemical Science has been carefully designed to provide a basic introduction to chemistry, including organic chemistry and biochemistry, for readers with little or no prior background in the subject. Manahan, bestselling author of many environmental texts, presents the material in a practical

Environmental Organic Chemistry

Author : René P. Schwarzenbach
Publisher : John Wiley & Sons
ISBN 13 : 0471743992
Total Pages : 1329 pages
Book Rating : 4.4/5 (717 download)

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Book Synopsis Environmental Organic Chemistry by : René P. Schwarzenbach

Download or read book Environmental Organic Chemistry written by René P. Schwarzenbach and published by John Wiley & Sons. This book was released on 2005-06-24 with total page 1329 pages. Available in PDF, EPUB and Kindle. Book excerpt: Environmental Organic Chemistry focuses on environmental factors that govern the processes that determine the fate of organic chemicals in natural and engineered systems. The information discovered is then applied to quantitatively assessing the environmental behaviour of organic chemicals. Now in its 2nd edition this book takes a more holistic view on physical-chemical properties of organic compounds. It includes new topics that address aspects of gas/solid partitioning, bioaccumulation, and transformations in the atmosphere. Structures chapters into basic and sophisticated sections Contains illustrative examples, problems and case studies Examines the fundamental aspects of organic, physical and inorganic chemistry - applied to environmentally relevant problems Addresses problems and case studies in one volume

Industrial Biotransformations

Author : Andreas Liese
Publisher : John Wiley & Sons
ISBN 13 : 3527614176
Total Pages : 428 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Industrial Biotransformations by : Andreas Liese

Download or read book Industrial Biotransformations written by Andreas Liese and published by John Wiley & Sons. This book was released on 2008-07-11 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: Industrial Biotransformations - a user-friendly and application-oriented up-to-date overview of one-step biotransformations of industrial importance. The data conferring each process is arranged in a convenient format to survey so that the processes can easily be compared. Each set of data is accompanied by key literature citations. As far as flow sheets of the processes are available, these are given reduced to their significant elements. An extensive index classified by substrates, products, enzymes, and companies provides direct access to each process organized in the order of enzyme classes. The reader will find all significant parameters characterizing the biotransformation itself and the process.