Biotechnological Applications of Phage and Phage-Derived Proteins

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Publisher : MDPI
ISBN 13 : 3039214411
Total Pages : 236 pages
Book Rating : 4.0/5 (392 download)

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Book Synopsis Biotechnological Applications of Phage and Phage-Derived Proteins by : Sílvio Santos

Download or read book Biotechnological Applications of Phage and Phage-Derived Proteins written by Sílvio Santos and published by MDPI. This book was released on 2019-10-01 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Phages have shown a high biotechnological potential with numerous applications. The advent of high-resolution microscopy techniques aligned with omic and molecular tools have revealed innovative phage features and enabled new processes that can be further exploited for biotechnological applications in a wide variety of fields. The high-quality original articles and reviews presented in this Special Issue demonstrate the incredible potential of phages and their derived proteins in a wide range of biotechnological applications for human benefit. Considering the emergence of amazing new available bioengineering tools and the high abundance of phages and the multitude of phage proteins yet to be discovered and studied, we believe that the upcoming years will present us with many more fascinating and new previously unimagined phage-based biotechnological applications.

Biotechnological Applications of Phage and Phage-Derived Proteins

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Publisher :
ISBN 13 : 9783039214426
Total Pages : 1 pages
Book Rating : 4.2/5 (144 download)

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Book Synopsis Biotechnological Applications of Phage and Phage-Derived Proteins by : Sílvio Santos

Download or read book Biotechnological Applications of Phage and Phage-Derived Proteins written by Sílvio Santos and published by . This book was released on 2019 with total page 1 pages. Available in PDF, EPUB and Kindle. Book excerpt: Phages have shown a high biotechnological potential with numerous applications. The advent of high-resolution microscopy techniques aligned with omic and molecular tools have revealed innovative phage features and enabled new processes that can be further exploited for biotechnological applications in a wide variety of fields. The high-quality original articles and reviews presented in this Special Issue demonstrate the incredible potential of phages and their derived proteins in a wide range of biotechnological applications for human benefit. Considering the emergence of amazing new available bioengineering tools and the high abundance of phages and the multitude of phage proteins yet to be discovered and studied, we believe that the upcoming years will present us with many more fascinating and new previously unimagined phage-based biotechnological applications.

Biotechnological Applications of Phage and Phage-Derived Proteins

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Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (136 download)

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Book Synopsis Biotechnological Applications of Phage and Phage-Derived Proteins by :

Download or read book Biotechnological Applications of Phage and Phage-Derived Proteins written by and published by . This book was released on 2019 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Phages have shown a high biotechnological potential with numerous applications. The advent of high-resolution microscopy techniques aligned with omic and molecular tools have revealed innovative phage features and enabled new processes that can be further exploited for biotechnological applications in a wide variety of fields. The high-quality original articles and reviews presented in this Special Issue demonstrate the incredible potential of phages and their derived proteins in a wide range of biotechnological applications for human benefit. Considering the emergence of amazing new available bioengineering tools and the high abundance of phages and the multitude of phage proteins yet to be discovered and studied, we believe that the upcoming years will present us with many more fascinating and new previously unimagined phage-based biotechnological applications.

Bacteriophage Applications in Biotechnology

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Publisher :
ISBN 13 : 9781641167949
Total Pages : 0 pages
Book Rating : 4.1/5 (679 download)

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Book Synopsis Bacteriophage Applications in Biotechnology by : Jayde Mason

Download or read book Bacteriophage Applications in Biotechnology written by Jayde Mason and published by . This book was released on 2023-09-26 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: A phage or bacteriophage is a virus that infects and replicates within bacteria and archaea. The diversity and abundance of phages in the biosphere makes them prime model organisms for studying the principles of evolution and ecology. Some major areas of research related to phages include the study of phages as promoters of bacterial evolution, novel therapeutic agents, and sources of genetic and diagnostic tools. There are various biotechnological applications of phages and phage-derived proteins in industries such as health, food science and safety, and agriculture. A major therapeutic application of phage is phage therapy, which is seen as a potential therapy for treating pathogenic bacterial infections. In the food industry, phages are extensively used for securing food products and preventing food spoilage caused by bacteria. This book outlines the applications of bacteriophages in the field of biotechnology. It presents researches and studies performed by experts across the globe. The book will prove to be immensely beneficial to students and researchers in this field.

Phage Display In Biotechnology and Drug Discovery

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Publisher : CRC Press
ISBN 13 : 0849359120
Total Pages : 770 pages
Book Rating : 4.8/5 (493 download)

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Book Synopsis Phage Display In Biotechnology and Drug Discovery by : Sachdev S. Sidhu

Download or read book Phage Display In Biotechnology and Drug Discovery written by Sachdev S. Sidhu and published by CRC Press. This book was released on 2005-07-27 with total page 770 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first and only guide to showcase the impact of phage display technology on drug discovery, this reference details the theories, principles, and methods impacting the field and demonstrates applications for peptide phage display, protein phage display, and the development of novel antibodies. Highlighting the current and future role of phage dis

Phage Display In Biotechnology and Drug Discovery, Second Edition

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Publisher : CRC Press
ISBN 13 : 9781439836491
Total Pages : 0 pages
Book Rating : 4.8/5 (364 download)

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Book Synopsis Phage Display In Biotechnology and Drug Discovery, Second Edition by : Sachdev S. Sidhu

Download or read book Phage Display In Biotechnology and Drug Discovery, Second Edition written by Sachdev S. Sidhu and published by CRC Press. This book was released on 2015-03-16 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Phage Display in Biotechnology and Drug Discovery, Second Edition provides a comprehensive view of the impact and promise of phage display in drug discovery and biotechnology. Building on the success of its previous edition, the book discusses current theories, principles, and methods in the field and demonstrates applications for peptide phage display, protein phage display, and the development of novel antibodies. The book provides readers with an overview of the amazing breadth of the impact that phage display technology has had on the study of proteins in general as well as the development of proteins. It will be a valuable resource for those interested in using phage display and recombinant antibodies in basic research and drug discovery.

Bacteriophages

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Publisher : BoD – Books on Demand
ISBN 13 : 1838804382
Total Pages : 144 pages
Book Rating : 4.8/5 (388 download)

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Book Synopsis Bacteriophages by : Renos Savva

Download or read book Bacteriophages written by Renos Savva and published by BoD – Books on Demand. This book was released on 2020-02-19 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bacteriophages are viruses that utilise bacterial cells as factories for their own propagation and as safe havens for their genomic material. They are capable of equipping bacteria with properties that bestow environmental advantages. They are also capable of specifically and efficiently killing bacteria.Bacteriophages are resilient in a wide diversity of environments, presumed to be as ancient as life itself, and are estimated to be the most numerous biological entities on the planet. Their overarching capacity to survive via molecular adaptation is supported by an arsenal of encoded enzymatic tools, which also enabled biotechnology. This volume includes contributions that describe bacteriophages as nanomachines, genetic engineers, and also as medicines and technologies of the future, including relevant production and process issues.

Bacteriophages

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Publisher : CRC Press
ISBN 13 : 1135511780
Total Pages : 716 pages
Book Rating : 4.1/5 (355 download)

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Book Synopsis Bacteriophages by : Elizabeth Kutter

Download or read book Bacteriophages written by Elizabeth Kutter and published by CRC Press. This book was released on 2004-12-28 with total page 716 pages. Available in PDF, EPUB and Kindle. Book excerpt: In response to the emergence of pathogenic bacteria that cannot be treated with current antibiotics, many researchers are revisiting the use of bacteriophages, or phages, to fight multidrug-resistant bacteria. Bacteriophages: Biology and Applications provides unparalleled, comprehensive information on bacteriophages and their applications, such as

Bacteriophages and Biofilms

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Publisher : Nova Biomedical Books
ISBN 13 : 9781617615887
Total Pages : 0 pages
Book Rating : 4.6/5 (158 download)

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Book Synopsis Bacteriophages and Biofilms by : Stephen T. Abedon

Download or read book Bacteriophages and Biofilms written by Stephen T. Abedon and published by Nova Biomedical Books. This book was released on 2011 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bacteriophages (phages) are the viruses of bacteria and biofilms that represent a frequent niche for bacteria, where they are embedded in extensive extracellular polymeric substances (EPS) and can be structured into complex microcolonies. As a consequence of the resulting spatial structure and heterogeneity, phage-bacterial interactions within biofilms can be more complicated than those between phages and planktonic bacteria. This book presents and discusses research which provides a better understanding of the biology of phages interacting with biofilms.

Bacteriophage

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Author :
Publisher : Caister Academic Press Limited
ISBN 13 :
Total Pages : 362 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Bacteriophage by : Stephen Mc Grath

Download or read book Bacteriophage written by Stephen Mc Grath and published by Caister Academic Press Limited. This book was released on 2007 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by eminent international researchers actively involved in the disparate areas of bacteriophage research this book focuses on the current rapid developments in this exciting field.

Phage Therapy: Past, Present and Future

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Publisher : Frontiers Media SA
ISBN 13 : 2889452514
Total Pages : 394 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis Phage Therapy: Past, Present and Future by : Stephen T. Abedon

Download or read book Phage Therapy: Past, Present and Future written by Stephen T. Abedon and published by Frontiers Media SA. This book was released on 2017-09-05 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: Historically, the first observation of a transmissible lytic agent that is specifically active against a bacterium (Bacillus anthracis) was by a Russian microbiologist Nikolay Gamaleya in 1898. At that time, however, it was too early to make a connection to another discovery made by Dmitri Ivanovsky in 1892 and Martinus Beijerinck in 1898 on a non-bacterial pathogen infecting tobacco plants. Thus the viral world was discovered in two of the three domains of life, and our current understanding is that viruses represent the most abundant biological entities on the planet. The potential of bacteriophages for infection treatment have been recognized after the discoveries by Frederick Twort and Felix d’Hérelle in 1915 and 1917. Subsequent phage therapy developments, however, have been overshadowed by the remarkable success of antibiotics in infection control and treatment, and phage therapy research and development persisted mostly in the former Soviet Union countries, Russia and Georgia, as well as in France and Poland. The dramatic rise of antibiotic resistance and especially of multi-drug resistance among human and animal bacterial pathogens, however, challenged the position of antibiotics as a single most important pillar for infection control and treatment. Thus there is a renewed interest in phage therapy as a possible additive/alternative therapy, especially for the infections that resist routine antibiotic treatment. The basis for the revival of phage therapy is affected by a number of issues that need to be resolved before it can enter the arena, which is traditionally reserved for antibiotics. Probably the most important is the regulatory issue: How should phage therapy be regulated? Similarly to drugs? Then the co-evolving nature of phage-bacterial host relationship will be a major hurdle for the production of consistent phage formulae. Or should we resort to the phage products such as lysins and the corresponding engineered versions in order to have accurate and consistent delivery doses? We still have very limited knowledge about the pharmacodynamics of phage therapy. More data, obtained in animal models, are necessary to evaluate the phage therapy efficiency compared, for example, to antibiotics. Another aspect is the safety of phage therapy. How do phages interact with the immune system and to what costs, or benefits? What are the risks, in the course of phage therapy, of transduction of undesirable properties such as virulence or antibiotic resistance genes? How frequent is the development of bacterial host resistance during phage therapy? Understanding these and many other aspects of phage therapy, basic and applied, is the main subject of this Topic.

Bacteriophages

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Publisher : Springer Nature
ISBN 13 : 3319419862
Total Pages : 1376 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Bacteriophages by : David R. Harper

Download or read book Bacteriophages written by David R. Harper and published by Springer Nature. This book was released on 2021-01-30 with total page 1376 pages. Available in PDF, EPUB and Kindle. Book excerpt: This first major reference work dedicated to the mannifold industrial and medical applications of bacteriophages provides both theoretical and practical insights into the emerging field of bacteriophage biotechnology. The book introduces to bacteriophage biology, ecology and history and reviews the latest technologies and tools in bacteriophage detection, strain optimization and nanotechnology. Usage of bacteriophages in food safety, agriculture, and different therapeutic areas is discussed in detail. This book serves as essential guide for researchers in applied microbiology, biotechnology and medicine coming from both academia and industry.

Phage Nanobiotechnology

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Publisher : Royal Society of Chemistry
ISBN 13 : 1847559921
Total Pages : 289 pages
Book Rating : 4.8/5 (475 download)

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Book Synopsis Phage Nanobiotechnology by : Valery Petrenko

Download or read book Phage Nanobiotechnology written by Valery Petrenko and published by Royal Society of Chemistry. This book was released on 2011-04-18 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: Several books and many papers have been published during the last decade on the design and the use of new nanomaterials in medicine and technology, which describe major concepts of nanotechnology. Meanwhile, a new promising type of nanomaterials-bacteriophages-emerged recently as a result of the evolution of phage display technique. Bacteriophages have a unique feature - completely the opposite of other nanomaterials -their structure and function are encrypted in their genomic DNA, which can be intentionally modified or even rewritten using routine genetic engineering techniques. In particular, a paradigm of landscape phage with multivalently displayed foreign peptides evolved, which allows constructing phage with unique surface architectures and emerged properties. Recently, phage, as a new kind of nanomaterials attracted the attention of specialists working in peripheral, and even very diverse areas from genetics and molecular biology, such as pharmaceutical science, material science, microelectronics, biosensors, detection, environmental sciences, etc. Penetration of the phage technology into these new disciplines required the development of a new instructive concept, which resulted in this publication. This comprehensive book, of value to researchers as well as scientists, introduces readers into this hot new area of phage nanobiotechnology. It summarises the existing data on the phage nanomaterials and discusses their use in different areas of medicine, science and technology. With contributions by top level experts and pioneers in phage display, the major goal of this book is to bring the phage display technique closer to specialists in these diverse areas of medicine, science and technology, where phage-derived nanomaterials can be most beneficial.

Bacteriophages in Health and Disease

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Publisher : CABI
ISBN 13 : 1845939840
Total Pages : 296 pages
Book Rating : 4.8/5 (459 download)

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Book Synopsis Bacteriophages in Health and Disease by : Paul Hyman

Download or read book Bacteriophages in Health and Disease written by Paul Hyman and published by CABI. This book was released on 2012 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bacteriophages are viruses that infect bacteria; as such, they have many potential uses for promoting health and combating disease. This book covers the many facets of phage-bacterial-human interaction in three sections: the role and impact of phages on natural bacterial communities, the potential to develop phage-based therapeutics and other aspects in which phages can be used to combat disease, including bacterial detection, bacterial epidemiology, the tracing of fecal contamination of water and decontamination of foods.

Growing and Handling of Bacterial Cultures

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Publisher :
ISBN 13 : 1789858461
Total Pages : 154 pages
Book Rating : 4.7/5 (898 download)

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Book Synopsis Growing and Handling of Bacterial Cultures by : Madhusmita Mishra

Download or read book Growing and Handling of Bacterial Cultures written by Madhusmita Mishra and published by . This book was released on 2019-12-04 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Bacterial Cell Wall Structure and Dynamics

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Publisher : Frontiers Media SA
ISBN 13 : 2889631524
Total Pages : 199 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Bacterial Cell Wall Structure and Dynamics by : Tobias Dörr

Download or read book Bacterial Cell Wall Structure and Dynamics written by Tobias Dörr and published by Frontiers Media SA. This book was released on 2019-12-27 with total page 199 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bacterial cells are encased in a cell wall, which is required to maintain cell shape and to confer physical strength to the cell. The cell wall allows bacteria to cope with osmotic and environmental challenges and to secure cell integrity during all stages of bacterial growth and propagation, and thus has to be sufficiently rigid. Moreover, to accommodate growth processes, the cell wall at the same time has to be a highly dynamic structure: During cell enlargement, division, and differentiation, bacteria continuously remodel, degrade, and resynthesize their cell wall, but pivotally need to assure cell integrity during these processes. Finally, the cell wall is also adjusted according to both environmental constraints and metabolic requirements. However, how exactly this is achieved is not fully understood. The major structural component of the bacterial cell wall is peptidoglycan (PG), a mesh-like polymer of glycan chains interlinked by short-chain peptides, constituting a net-like macromolecular structure that has historically also termed murein or murein sacculus. Although the basic structure of PG is conserved among bacteria, considerable variations occur regarding cross-bridging, modifications, and attachments. Moreover, different structural arrangements of the cell envelope exist within bacteria: a thin PG layer sandwiched between an inner and outer membrane is present in Gram-negative bacteria, and a thick PG layer decorated with secondary glycopolymers including teichoic acids, is present in Gram-positive bacteria. Furthermore, even more complex envelope structures exist, such as those found in mycobacteria. Crucially, all bacteria possess a multitude of often redundant lytic enzymes, termed “autolysins”, and other cell wall modifying and synthesizing enzymes, allowing to degrade and rebuild the various structures covering the cells. However, how cell wall turnover and cell wall biosynthesis are coordinated during different stages of bacterial growth is currently unclear. The mechanisms that prevent cell lysis during these processes are also unclear. This Research Topic focuses on the dynamics of the bacterial cell wall, its modifications, and structural rearrangements during cell growth and differentiation. It pays particular attention to the turnover of PG, its breakdown and recycling, as well as the regulation of these processes. Other structures, for example, secondary polymers such as teichoic acids, which are dynamically changed during bacterial growth and differentiation, are also covered. In recent years, our view on the bacterial cell envelope has undergone a dramatic change that challenged old models of cell wall structure, biosynthesis, and turnover. This collection of articles aims to contribute to new understandings of bacterial cell wall structure and dynamics.

Lactic Acid Bacteria: Genetics, Metabolism and Applications

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Publisher : Springer Science & Business Media
ISBN 13 : 9401720274
Total Pages : 399 pages
Book Rating : 4.4/5 (17 download)

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Book Synopsis Lactic Acid Bacteria: Genetics, Metabolism and Applications by : W.N. Konings

Download or read book Lactic Acid Bacteria: Genetics, Metabolism and Applications written by W.N. Konings and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 399 pages. Available in PDF, EPUB and Kindle. Book excerpt: In ancient times foods fermented with lactic acid bacteria already constituted an important part of the human diet. From then on, lactic acid bacteria have played an essential role in the preservation of food raw materials and have contributed to the nutritional, organoleptic and health properties of human food products and animal feed. The important function that lactic acid bacteria still have in the production of foods all over the world has resulted in a growing scientific interest in these micro-organisms by academic research groups as well as by industry. During the last 15 years, this research has been stimulated by major internationally coordinated funding efforts that have resulted in a variety of important scientific breakthroughs and have led to new applications. Written by international experts in the field, this issue of Antonie van Leeuwenhoek documents these developments with respect to genetics, metabolism and the application of lactic acid bacteria for industrial and potential medical applications. In this book the first complete genome of a lactic acid bacterium is presented. The book will serve as a reference source and also as an indispensable source of information for further development and exploration of the field.