Biopharmaceuticals In Plants

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Biopharmaceuticals in Plants

Author : Kathleen Laura Hefferon
Publisher : CRC Press
ISBN 13 : 1439804753
Total Pages : 230 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Biopharmaceuticals in Plants by : Kathleen Laura Hefferon

Download or read book Biopharmaceuticals in Plants written by Kathleen Laura Hefferon and published by CRC Press. This book was released on 2009-11-10 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: Transgenic plants present enormous potential to become one of the most cost-effective and safe systems for large-scale production of proteins for industrial, pharmaceutical, veterinary, and agricultural uses. Over the past decade, much progress has been made with respect to the development of vaccines, antibodies, and other therapeutic proteins. Bi

Plant-derived Pharmaceuticals

Author : Kathleen L Hefferon
Publisher : CABI
ISBN 13 : 1780643438
Total Pages : 182 pages
Book Rating : 4.7/5 (86 download)

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Book Synopsis Plant-derived Pharmaceuticals by : Kathleen L Hefferon

Download or read book Plant-derived Pharmaceuticals written by Kathleen L Hefferon and published by CABI. This book was released on 2014-10-29 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt: Describing recent developments in the engineering and generation of plants as production platforms for biopharmaceuticals, this book includes both vaccines and monoclonal antibodies. It has a particular emphasis on targeting diseases which predominate in less developed countries, encompassing the current state of technologies and describing expression systems and applications. This book also includes a variety of vaccine case studies, protecting against pervasive infectious diseases such as rabies, influenza and HIV.

Transgenic Medicinal Plants

Author : Y.P.S. Bajaj
Publisher : Springer Science & Business Media
ISBN 13 : 364258439X
Total Pages : 390 pages
Book Rating : 4.6/5 (425 download)

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Book Synopsis Transgenic Medicinal Plants by : Y.P.S. Bajaj

Download or read book Transgenic Medicinal Plants written by Y.P.S. Bajaj and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprising 26 chapters, this volume deals with the genetic transformation of medicinal plants. It describes methods to obtain plants resistant to insects, diseases, herbicides, and plants with an increased production of compounds of medicinal and pharmaceutical importance. The plant species included are Ajuga reptans, Anthemis nobilis, Astragalus spp., Atropa belladonna, Catharanthus roseus, Datura spp., Duboisia leichhardtii, Fagopyrum spp., Glycyrrhiza uralensis, Lobelia spp., Papaver somniferum, Panax ginseng, Peganum hamala, Perezia spp., Pimpinella anisum, Phyllanthus niruri, Salvia miltiorrhiza, Scoparia dulcis, Scutellaria baicalesis, Serratula tinctoria, Solanum aculeatissimum, Solanum commersonii, Swainsona galegifolia, tobacco, and Vinca minor. The book is of special interest to advanced students, teachers, and researchers in the fields of pharmacy, plant tissue culture, phytochemistry, molecular biology, biomedical engineering, and plant biotechnology in general.

Modern Applications of Plant Biotechnology in Pharmaceutical Sciences

Author : Saurabh Bhatia
Publisher : Academic Press
ISBN 13 : 0128024984
Total Pages : 452 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Modern Applications of Plant Biotechnology in Pharmaceutical Sciences by : Saurabh Bhatia

Download or read book Modern Applications of Plant Biotechnology in Pharmaceutical Sciences written by Saurabh Bhatia and published by Academic Press. This book was released on 2015-07-22 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern Applications of Plant Biotechnology in Pharmaceutical Sciences explores advanced techniques in plant biotechnology, their applications to pharmaceutical sciences, and how these methods can lead to more effective, safe, and affordable drugs. The book covers modern approaches in a practical, step-by-step manner, and includes illustrations, examples, and case studies to enhance understanding. Key topics include plant-made pharmaceuticals, classical and non-classical techniques for secondary metabolite production in plant cell culture and their relevance to pharmaceutical science, edible vaccines, novel delivery systems for plant-based products, international industry regulatory guidelines, and more. Readers will find the book to be a comprehensive and valuable resource for the study of modern plant biotechnology approaches and their pharmaceutical applications. - Builds upon the basic concepts of cell and plant tissue culture and recombinant DNA technology to better illustrate the modern and potential applications of plant biotechnology to the pharmaceutical sciences - Provides detailed yet practical coverage of complex techniques, such as micropropogation, gene transfer, and biosynthesis - Examines critical issues of international importance and offers real-life examples and potential solutions

Pharmaceutical Biotechnology

Author : Oliver Kayser
Publisher : John Wiley & Sons
ISBN 13 : 3527329943
Total Pages : 677 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Pharmaceutical Biotechnology by : Oliver Kayser

Download or read book Pharmaceutical Biotechnology written by Oliver Kayser and published by John Wiley & Sons. This book was released on 2012-05-21 with total page 677 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition of a very successful book is thoroughly updated with existing chapters completely rewritten while the content has more than doubled from 16 to 36 chapters. As with the first edition, the focus is on industrial pharmaceutical research, written by a team of industry experts from around the world, while quality and safety management, drug approval and regulation, patenting issues, and biotechnology fundamentals are also covered. In addition, this new edition now not only includes biotech drug development but also the use of biopharmaceuticals in diagnostics and vaccinations. With a foreword by Robert Langer, Kenneth J Germeshausen Professor of Chemical and Biomedical Engineering at MIT and member of the National Academy of Engineering and the National Academy of Sciences.

Pharming

Author : Eckard Rehbinder
Publisher : Springer Science & Business Media
ISBN 13 : 3540857931
Total Pages : 341 pages
Book Rating : 4.5/5 (48 download)

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Book Synopsis Pharming by : Eckard Rehbinder

Download or read book Pharming written by Eckard Rehbinder and published by Springer Science & Business Media. This book was released on 2008-09-27 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: A recently established technique termed pharming uses genetically modified plants and animals for the production of biopharmaceuticals. The present interdisciplinary study comprises an extended overview of the state of the art of pharming, as well as in depth analyses of the environmental risks and other ethical and legal issues of pharming. Public attitudes to pharming are investigated on the basis of an original survey in 15 countries worldwide. The study concludes with specific recommendations addressed towards science, industry and politics.

Plant Biotechnology and Transgenic Plants

Author : Kirsi-Marja Oksman-Caldentey
Publisher : CRC Press
ISBN 13 : 0824743784
Total Pages : 637 pages
Book Rating : 4.8/5 (247 download)

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Book Synopsis Plant Biotechnology and Transgenic Plants by : Kirsi-Marja Oksman-Caldentey

Download or read book Plant Biotechnology and Transgenic Plants written by Kirsi-Marja Oksman-Caldentey and published by CRC Press. This book was released on 2002-08-14 with total page 637 pages. Available in PDF, EPUB and Kindle. Book excerpt: Contains case studies illustrating the cell culture production of pigments, flavors, and antineoplastic compounds Plant Biotechnology and Transgenic Plants covers topics that range from food to fragrances to fuel. It includes discussions of technologies and research on the engineering, synthesis, utilization, and control of primary and secondary plant metabolites such as carbohydrates, amino acids, lipids, polymers, proteins, and phytochemicals for industrial, pharmaceutical, and food and feed applications. The editors put the emphasis on recent methods in farming, plant propagation, and breeding and modern procedures to formulate more effective biopharmaceuticals.

Biotechnology and Safety Assessment

Author : John A. Thomas
Publisher : Elsevier
ISBN 13 : 008052818X
Total Pages : 505 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Biotechnology and Safety Assessment by : John A. Thomas

Download or read book Biotechnology and Safety Assessment written by John A. Thomas and published by Elsevier. This book was released on 2002-09-05 with total page 505 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive treatise on new developments in biotechnology, the authors of Biotechnology and Safety Assessment, 3e, bring readers an up-to-date review of food safety issues, pre-clinical safety and development of new foods and drugs, plant biotechnology, food allergies and safety assessment, and consumer benefits with regard to genetically modified food. Tomorrow's foods will be obtained from genetically modified crops, offering consumers higher nutritional value and more of it. Our medications will be obtained through a variety of biotechnological procedures yielding more potent and specific medications for diseases and vaccines. In order to make this view of the future come to light, John A. Thomas and Roy L. Fuchs have updated their classic in order to keep readers one step ahead. Written by internationally recognized molecular biologists, plant agronomists, microbiologists, toxicologists, nutritionists, and regulatory authorities, this third edition is an excellent and authoritative resource, making it a valuable resource to any biomedical library or scientific bookshelf. - Provides timely coverage on topics of agribiotechnology and biotherapeutics - Describes the recent progress in genetically modified crops and their safety - Presents an update of the newer developments in therapeutic agents - Discusses role of genetically modified microorganisms in the development of new food products - Outlines various global regulatory issues relating to GM crops - Addresses environmental and ecological topics related to GM crops

Biopharmaceuticals

Author : Ming-Kung Yeh
Publisher : BoD – Books on Demand
ISBN 13 : 1789237181
Total Pages : 140 pages
Book Rating : 4.7/5 (892 download)

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Book Synopsis Biopharmaceuticals by : Ming-Kung Yeh

Download or read book Biopharmaceuticals written by Ming-Kung Yeh and published by BoD – Books on Demand. This book was released on 2018-09-19 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biopharmaceuticals are derived from biological sources, either live organisms or their active components; nowadays, they are mainly produced by biotechnologies. Biopharmaceuticals are extensively used in the treatment of various diseases such as cardiovascular, metabolic, neurological diseases, cancer, and others for which there are no available therapeutic methods. With the advance of science, biopharmaceuticals have revolutionized the treatment, prevention, and diagnosis of many patients with disabling and life-threatening diseases. Innovative biopharmaceuticals definitely improve the life quality of patients and enhance the effectiveness of the healthcare system. This book encompasses the discovery, production, application, and regulation of biopharmaceuticals to demonstrate their research achievement, prospects, and challenges. We expect the significance of biopharmaceuticals to be revealed and emphasized by this book.

Molecular Farming

Author : Rainer Fischer
Publisher : John Wiley & Sons
ISBN 13 : 9783527307869
Total Pages : 342 pages
Book Rating : 4.3/5 (78 download)

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Book Synopsis Molecular Farming by : Rainer Fischer

Download or read book Molecular Farming written by Rainer Fischer and published by John Wiley & Sons. This book was released on 2004-10-25 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: Here, authors from academia and industry provide an exciting overview of current production technologies and the fascinating possibilities for future applications. Topics include chloroplast-derived antibodies, biopharmaceuticals and edible vaccines, production of antibodies in plants and plant cell suspension cultures, production of spider silk proteins in plants, and glycosylation of plant produced proteins. The whole is rounded off by chapters on the demands and expectations made on molecular farming by pharmaceutical corporations and the choice of crop species in improving recombinant protein levels. Of interest to biotechnologists, gene technologists, molecular biologists and protein biochemists in university as well as the biotechnological and pharmaceutical industries.

Plant-produced Microbial Vaccines

Author : Alexander V. Karasev
Publisher : Springer Science & Business Media
ISBN 13 : 3540708685
Total Pages : 126 pages
Book Rating : 4.5/5 (47 download)

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Book Synopsis Plant-produced Microbial Vaccines by : Alexander V. Karasev

Download or read book Plant-produced Microbial Vaccines written by Alexander V. Karasev and published by Springer Science & Business Media. This book was released on 2009-04-29 with total page 126 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, plants have been increasingly explored for production of biomedicines and vaccine components. The two main advantages of plant systems are low cost and a greater potential for scalability as compared to microbial or animal systems. An additional advantage from the public health point of view is high safety compared to animal systems, which is important for vaccine production: there are no known plant pathogens capable of replicating in animals, and in humans in particular. A particular antigen or a protein has to be expressed in a plant using one of many available platforms; this antigen/protein subsequently needs to be purified or processed, and later formulated into a vaccine or a therapeutic; these need to be delivered to a human or animal body via an appropriate route. Naturally, all these vaccines and therapeutics must be subjected to regulatory approvals prior to their use. Thus, the challenge is to adapt plant-based platforms for production of cost-efficient biomedicals that can be approved by FDA for use as vaccine components or therapeutics which will be competitive against existing vaccines and drugs. This volume attempts to address the entire spectrum of challenges facing the nascent field of plant-based biomedicals, from the selection of an appropriate production platform to specific methods of downstream processing and regulatory approval issues.

Chemicals via Higher Plant Bioengineering

Author : Fereidoon Shahidi
Publisher : Springer Science & Business Media
ISBN 13 : 9780306461170
Total Pages : 296 pages
Book Rating : 4.4/5 (611 download)

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Book Synopsis Chemicals via Higher Plant Bioengineering by : Fereidoon Shahidi

Download or read book Chemicals via Higher Plant Bioengineering written by Fereidoon Shahidi and published by Springer Science & Business Media. This book was released on 1999-05-31 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Food and raw material for its production was generally produced via the traditional agriculture. On the other hand, novel chemicals were manufactured in the laboratory or extracted from plant and animal sources. However, as the world population is steadily in creasing, there is a decrease in traditional agriculture productivity and concerns are also expressed over the damage inflicted to the environment and restrictions that might be en forced in food production. At the same time, there is an increasing demand for high qual ity agricultural products as well as for food ingredients related to both the traditional or newly discovered nutrients or phytochemicals. Trends and developments,~n the area of plant biotechnology and bioengineering has allowed manipulation of genes' !lnd/or insertion of new genes, thus production of trans genic plants. Starting from the introduction of agronomic traits, particularly stress resis tance to diverse environmental factors, process and sensory characteristics, food quality and production of novel varieties of plant-based products through genetic engineering, biotechnology is changing the,;agriculture and the concept of production of plant-ba~~d raw materials. Increasing attention is being paid on research for production of plants !pat can provide a wide array of food and non-food products. Perhaps the first non-food pro,d uct that plant biotechnology would achieve is production of large scale custom-designed industrial oils, but the list of chemicals is long, ranging" from oils and specific triacyl glycerols to biopolymers, enzymes, blood components, amo~g others.

Applied Plant Genomics and Biotechnology

Author : Palmiro Poltronieri
Publisher : Woodhead Publishing
ISBN 13 : 0081000715
Total Pages : 354 pages
Book Rating : 4.0/5 (81 download)

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Book Synopsis Applied Plant Genomics and Biotechnology by : Palmiro Poltronieri

Download or read book Applied Plant Genomics and Biotechnology written by Palmiro Poltronieri and published by Woodhead Publishing. This book was released on 2015-01-27 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: Applied plant genomics and biotechnology reviews the recent advancements in the post-genomic era, discussing how different varieties respond to abiotic and biotic stresses, investigating epigenetic modifications and epigenetic memory through analysis of DNA methylation states, applicative uses of RNA silencing and RNA interference in plant physiology and in experimental transgenics, and plants modified to produce high-value pharmaceutical proteins. The book provides an overview of research advances in application of RNA silencing and RNA interference, through Virus-based transient gene expression systems, Virus induced gene complementation (VIGC), Virus induced gene silencing (Sir VIGS, Mr VIGS) Virus-based microRNA silencing (VbMS) and Virus-based RNA mobility assays (VRMA); RNA based vaccines and expression of virus proteins or RNA, and virus-like particles in plants, the potential of virus vaccines and therapeutics, and exploring plants as factories for useful products and pharmaceuticals are topics wholly deepened. The book reviews and discuss Plant Functional Genomic studies discussing the technologies supporting the genetic improvement of plants and the production of plant varieties more resistant to biotic and abiotic stresses. Several important crops are analysed providing a glimpse on the most up-to-date methods and topics of investigation. The book presents a review on current state of GMO, the cisgenesis-derived plants and novel plant products devoid of transgene elements, discuss their regulation and the production of desired traits such as resistance to viruses and disease also in fruit trees and wood trees with long vegetative periods. Several chapters cover aspects of plant physiology related to plant improvement: cytokinin metabolism and hormone signaling pathways are discussed in barley; PARP-domain proteins involved in Stress-Induced Morphogenetic Response, regulation of NAD signaling and ROS dependent synthesis of anthocyanins. Apple allergen isoforms and the various content in different varieties are discussed and approaches to reduce their presence. Euphorbiaceae, castor bean, cassava and Jathropa are discussed at genomic structure, their diseases and viruses, and methods of transformation. Rice genomics and agricultural traits are discussed, and biotechnology for engineering and improve rice varieties. Mango topics are presented with an overview of molecular methods for variety differentiation, and aspects of fruit improvement by traditional and biotechnology methods. Oilseed rape is presented, discussing the genetic diversity, quality traits, genetic maps, genomic selection and comparative genomics for improvement of varieties. Tomato studies are presented, with an overview on the knowledge of the regulatory networks involved in flowering, methods applied to study the tomato genome-wide DNA methylation, its regulation by small RNAs, microRNA-dependent control of transcription factors expression, the development and ripening processes in tomato, genomic studies and fruit modelling to establish fleshy fruit traits of interest; the gene reprogramming during fruit ripening, and the ethylene dependent and independent DNA methylation changes. - provides an overview on the ongoing projects and activities in the field of applied biotechnology - includes examples of different crops and applications to be exploited - reviews and discusses Plant Functional Genomic studies and the future developments in the field - explores the new technologies supporting the genetic improvement of plants

Biopharmaceuticals

Author : Basanta Kumara Behera
Publisher : CRC Press
ISBN 13 : 1351013130
Total Pages : 300 pages
Book Rating : 4.3/5 (51 download)

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Book Synopsis Biopharmaceuticals by : Basanta Kumara Behera

Download or read book Biopharmaceuticals written by Basanta Kumara Behera and published by CRC Press. This book was released on 2020-12-07 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biopharmaceuticals: Challenges and Opportunities This book highlights how the traditional microbial process technology has been upgraded for the production of biologic drugs how manufacturing processes have evolved to meet the global market demand with quality products under the guidelines of internally recognized regulatory bodies. It also carries information on how, armed with a deeper understanding of life-threatening diseases, biopharmaceutical companies and the life sciences industry have developed formal and informal partnerships with researchers in institutes, universities, and other R&D organizations to fulfil timely, quality production with perfect safety and security. One of the most interesting aspects of this book is the conceptual development of personalized medicine (or precision medicine) to provide the right treatment to the right patient, at the right dose at an earlier stage of development, for genetic diseases. Besides this, it also highlights the most challenging aspects of modern biopharmaceutical science, focusing on the hot topics such as design and development of biologic drugs; the use of diversified groups of host cells belonging to animals, plants, microbes, insects, and mammals; stem cell therapy and gene therapy; supply chain management of biopharmaceuticals; and the future scope of biopharmaceutical industry development. This book is the latest resource for a wide circle of scientists, students, and researchers involved in understanding and implementing the knowledge of biopharmaceuticals to develop life-saving biologic drugs and to bring awareness to the development of personalized treatment that can potentially offer patients a faster diagnosis, fewer side effects, and better outcomes. Features: Explains how the traditional cell culture methodology has been changed to a fully continuous or partially continuous process Explains how to design and fabricate living organs of body by 3D bioprinting technology Focuses on how a biopharmaceutical company deals with various problems of regulatory bodies and develops innovative biologic drugs Narrates in detail the updated information on stem cell therapy and gene therapy Explains the development strategies and clinical significance of biosimilars and biobetters Highlights the supply chain management of biopharmaceuticals

Biopharmaceuticals

Author : Gary Walsh
Publisher : John Wiley & Sons
ISBN 13 : 1118687388
Total Pages : 544 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Biopharmaceuticals by : Gary Walsh

Download or read book Biopharmaceuticals written by Gary Walsh and published by John Wiley & Sons. This book was released on 2013-04-29 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: The latest edition of this highly acclaimed textbook, provides a comprehensive and up-to-date overview of the science and medical applications of biopharmaceutical products. Biopharmaceuticals refers to pharmaceutical substances derived from biological sources, and increasingly, it is synonymous with 'newer' pharmaceutical substances derived from genetic engineering or hybridoma technology. This superbly written review of the important areas of investigation in the field, covers drug production, plus the biochemical and molecular mechanisms of action together with the biotechnology of major biopharmaceutical types on the market or currently under development. There is also additional material reflecting both the technical advances in the area and detailed information on key topics such as the influence of genomics on drug discovery.

Molecular Farming of Plants and Animals for Human and Veterinary Medicine

Author : L. Erickson
Publisher : Springer Science & Business Media
ISBN 13 : 9401723176
Total Pages : 381 pages
Book Rating : 4.4/5 (17 download)

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Book Synopsis Molecular Farming of Plants and Animals for Human and Veterinary Medicine by : L. Erickson

Download or read book Molecular Farming of Plants and Animals for Human and Veterinary Medicine written by L. Erickson and published by Springer Science & Business Media. This book was released on 2013-04-18 with total page 381 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular farming has been hailed as the "third wave" of genetically-modified organisms produced through biotechnology for the bio-based economy of the future. Unlike products of the first wave, such as herbicide resistant crop plants, which were perceived to benefit only the farmers who used them and the agrochemical companies who developed them, products of molecular farming are designed specifically for the benefit of the consumer. Such products could be purified from food or non-food organisms for a range of applications in industry, as well as animal and human health. Alternatively, the products of this technology could be consumed more directly in some edible format, such as milk, eggs, fruits or vegetables. There is a rapidly-growing interest Qn the part of the public as well as in the medical community in the role food plays in health, especially in the immunophysiological impact of food over and above the role of basic nutrition.

Molecular Pharming

Author : Allison R. Kermode
Publisher : John Wiley & Sons
ISBN 13 : 1118801482
Total Pages : 496 pages
Book Rating : 4.1/5 (188 download)

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Book Synopsis Molecular Pharming by : Allison R. Kermode

Download or read book Molecular Pharming written by Allison R. Kermode and published by John Wiley & Sons. This book was released on 2018-03-12 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: A single volume collection that surveys the exciting field of plant-made pharmaceuticals and industrial proteins This comprehensive book communicates the recent advances and exciting potential for the expanding area of plant biotechnology and is divided into six sections. The first three sections look at the current status of the field, and advances in plant platforms and strategies for improving yields, downstream processing, and controlling post-translational modifications of plant-made recombinant proteins. Section four reviews high-value industrial and pharmacological proteins that are successfully being produced in established and emerging plant platforms. The fifth section looks at regulatory challenges facing the expansion of the field. The final section turns its focus toward small molecule therapeutics, drug screening, plant specialized metabolites, and plants as model organisms to study human disease processes. Molecular Pharming: Applications, Challenges and Emerging Areas offers in-depth coverage of molecular biology of plant expression systems and manipulation of glycosylation processes in plants; plant platforms, subcellular targeting, recovery, and downstream processing; plant-derived protein pharmaceuticals and case studies; regulatory issues; and emerging areas. It is a valuable resource for researchers that are in the field of plant molecular pharming, as well as for those conducting basic research in gene expression, protein quality control, and other subjects relevant to molecular and cellular biology. Broad ranging coverage of a key area of plant biotechnology Describes efforts to produce pharmaceutical and industrial proteins in plants Provides reviews of recent advances and technology breakthroughs Assesses realities of regulatory and cost hurdles Forward looking with coverage of small molecule technologies and the use of plants as models of human disease processes Providing wide-ranging and unique coverage, Molecular Pharming: Applications, Challenges and Emerging Areas will be of great interest to the plant science, plant biotechnology, protein science, and pharmacological communities.