Biomimetic Materials for Tissue Regenerations, 2nd edition

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Publisher : Frontiers Media SA
ISBN 13 : 2832506283
Total Pages : 305 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Biomimetic Materials for Tissue Regenerations, 2nd edition by : Mariappan Rajan

Download or read book Biomimetic Materials for Tissue Regenerations, 2nd edition written by Mariappan Rajan and published by Frontiers Media SA. This book was released on 2022-10-20 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: In tissue engineering, the ultimate goal is to engineer an entire functioning organ that requires building complex structures of different tissue types. A three-dimensional scaffold seeded with desired cell types. In order to resemble the natural formations of the organs, cells have to be correctly located in relation to one another. It has been shown in cocultures that cells have the capability of spontaneous tissue-like organization when seeded into the scaffold. The ideal scaffolds should have an interconnected porous structure, well-designed pore size and adequate porosity to allow cell attachment, proliferation and differentiation. Moreover, effective bioactive agents and nutrient exchange are crucial during new tissue development. Thus the individual organ cell is a specific mechanism for the construction or regeneration of the cells. Artificial scaffolds have been applied and used as supporting structures for cell cultures as well as for the domination of cell growth in the repair of impaired tissues or organs. During the cell regeneration, the scaffold temporarily helps in cell regeneration and gradually biodegrade either in the course of the healing process or after, and a new tissue with a desired shape and properties is produced. The challenge of tissue engineering is to mimic what happens in nature. Attempts are being made to engineer in vitro practically every tissue and organ in the body. Work is proceeding in creating tissue-engineered liver, nerve, kidney, intestine, pancreas, and even heart muscle and valves. In the area of connective tissues, work has been ongoing worldwide for many years in the engineering of tendon, ligament, bone, and cartilage. Recently, the number of reports was succeeded in skin, bladder, airway, and bone, where tissue-engineered constructs have been used successfully in patients. This Research Topic is the collection of body organ regeneration materials and their cell adhesion and migration for the development and regeneration of tissues. Biomimetic materials promise to advance in current understanding of organ regeneration and repair by providing tools to recapitulate and monitor relevant properties of cellular - microenvironment interactions. Although cell adhesion, migration, and development aspects of tissues have shown success in the clinic, better, more intricate models are needed to understand drivers of tissue repair and regeneration fully. Tissue engineering bears tremendous potential toward gaining a complete understanding of the underlying biological and physical mechanisms advancing the treatment of damaged organs. The following Research Topic “Bio-mimetic materials for tissue regenerations” discusses examples of progress toward this objective. • Bio-mimicking scaffold materials for tissue regeneration • Cell adhesion to scaffold materials • Role of materials for the migration of cells • Mechanisms of cell growth for organ development

Bio-Inspired Regenerative Medicine

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Author :
Publisher : CRC Press
ISBN 13 : 9814669156
Total Pages : 404 pages
Book Rating : 4.8/5 (146 download)

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Book Synopsis Bio-Inspired Regenerative Medicine by : Anna Tampieri

Download or read book Bio-Inspired Regenerative Medicine written by Anna Tampieri and published by CRC Press. This book was released on 2016-03-30 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a wide and interdisciplinary overview of the current state of the art in the development of biomimetic materials for tissue regeneration on the basis of relevant and high-impact clinical needs. It specifically emphasizes the regeneration of bone, cartilage, and osteochondral tissues as well as soft tissues such as nerves, heart,

Biomimetic Biomaterials for Tissue Regeneration and Drug Delivery

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Author :
Publisher : Springer
ISBN 13 : 9789811645655
Total Pages : 156 pages
Book Rating : 4.6/5 (456 download)

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Book Synopsis Biomimetic Biomaterials for Tissue Regeneration and Drug Delivery by : Mamoni Dash

Download or read book Biomimetic Biomaterials for Tissue Regeneration and Drug Delivery written by Mamoni Dash and published by Springer. This book was released on 2022-05-30 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book illustrates the influence of biomimetics in the field of tissue engineering and drug delivery. These two distinct fields of regenerative medicine have greatly benefited from the concept of biomimetics, which focuses on using or imitating nature to develop materials for improving human lives. The book begins by highlighting the relevance and recent advances in biomimetic biomaterials. An updated and innovative content has been presented in terms of biomimetic systems that are being utilized in controlled delivery and stem cell therapy. Further, the book reviews the role of these materials in enhanced capacity for drug loading, cellular uptake, and controlled release within the target cells. The book includes advanced techniques for characterizing biomimetic biomaterials and highlights their pivotal role in providing three-dimensional templates and synthetic extracellular matrices.

Engineered biomimetic micro/ nano-materials for tissue regeneration

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Publisher : Frontiers Media SA
ISBN 13 : 2832547494
Total Pages : 156 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Engineered biomimetic micro/ nano-materials for tissue regeneration by : Juan Wang

Download or read book Engineered biomimetic micro/ nano-materials for tissue regeneration written by Juan Wang and published by Frontiers Media SA. This book was released on 2024-04-08 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Biomimetic biomaterials

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Publisher : Elsevier Inc. Chapters
ISBN 13 : 0128088087
Total Pages : 60 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Biomimetic biomaterials by : S. Sprio

Download or read book Biomimetic biomaterials written by S. Sprio and published by Elsevier Inc. Chapters. This book was released on 2013-09-30 with total page 60 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientific research on tissue regeneration is increasingly becoming the most promising response to a number of disabling pathologies with huge impact on the progressively growing and ageing world population. The biomimicry of scaffolds with the target tissue is now universally considered to be a key requirement to properly instruct cells towards the restoration of physiological functioning. In this respect, the present chapter presents an overview of recent findings on biomimetic materials and devices addressed to bone and osteochondral tissues as well as soft organ regeneration. Particular focus is given to new apatite phases, including the newly discovered superparamagnetic apatite and processes to develop ceramic, polymeric and hybrid regenerative scaffolds.

Biomimicked Biomaterials

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Publisher : Springer Nature
ISBN 13 : 9811532621
Total Pages : 200 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Biomimicked Biomaterials by : Heung Jae Chun

Download or read book Biomimicked Biomaterials written by Heung Jae Chun and published by Springer Nature. This book was released on 2020-06-29 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the second of two volumes that together offer a comprehensive account of cutting-edge advances in the development of biomaterials for use within tissue engineering and regenerative medicine. In this volume, which is devoted to biomimetic biomaterials, the opening section discusses bone regeneration by means of duck’s feet-derived collagen scaffold and the use of decellularized extracellular matrices. The role of various novel biomimetic hydrogels in regenerative medicine is then considered in detail. The third section focuses on the control of stem cell fate by biomimetic biomaterials, covering exosome-integrated biomaterials for bone regeneration, cellular responses to materials for biomedical engineering, and the regulation of stem cell functions by micropatterned structures. Finally, the use of nano-intelligent biocomposites in regenerative medicine is addressed, with discussion of, for example, recent advances in biphasic calcium phosphate bioceramics and blood-contacting polymeric biomaterials. The authors are recognized experts in the interdisciplinary field of regenerative medicine and the book will be of value for all with an interest in regenerative medicine based on biomaterials.

Comprehensive Biomaterials II

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Publisher : Elsevier
ISBN 13 : 0081006926
Total Pages : 4865 pages
Book Rating : 4.0/5 (81 download)

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Book Synopsis Comprehensive Biomaterials II by : Kevin Healy

Download or read book Comprehensive Biomaterials II written by Kevin Healy and published by Elsevier. This book was released on 2017-05-18 with total page 4865 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Biomaterials II, Second Edition, Seven Volume Set brings together the myriad facets of biomaterials into one expertly-written series of edited volumes. Articles address the current status of nearly all biomaterials in the field, their strengths and weaknesses, their future prospects, appropriate analytical methods and testing, device applications and performance, emerging candidate materials as competitors and disruptive technologies, research and development, regulatory management, commercial aspects, and applications, including medical applications. Detailed coverage is given to both new and emerging areas and the latest research in more traditional areas of the field. Particular attention is given to those areas in which major recent developments have taken place. This new edition, with 75% new or updated articles, will provide biomedical scientists in industry, government, academia, and research organizations with an accurate perspective on the field in a manner that is both accessible and thorough. Reviews the current status of nearly all biomaterials in the field by analyzing their strengths and weaknesses, performance, and future prospects Covers all significant emerging technologies in areas such as 3D printing of tissues, organs and scaffolds, cell encapsulation; multimodal delivery, cancer/vaccine - biomaterial applications, neural interface understanding, materials used for in situ imaging, and infection prevention and treatment Effectively describes the many modern aspects of biomaterials from basic science, to clinical applications

Nanotechnology and Regenerative Engineering

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Publisher : CRC Press
ISBN 13 : 1466585374
Total Pages : 480 pages
Book Rating : 4.4/5 (665 download)

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Book Synopsis Nanotechnology and Regenerative Engineering by : Cato T. Laurencin

Download or read book Nanotechnology and Regenerative Engineering written by Cato T. Laurencin and published by CRC Press. This book was released on 2014-10-28 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanotechnology and regenerative engineering have emerged to the forefront as the most versatile and innovative technologies to foster novel therapeutic techniques and strategies of the twenty-first century. The first edition of Nanotechnology and Tissue Engineering: The Scaffold was the first comprehensive source to explain the developments in nanostructured biomaterials for tissue engineering, the relevance of nanostructured materials in tissue regeneration, and the current applications of nanostructured scaffolds for engineering various tissues. This fully revised second edition, renamed Nanotechnology and Regenerative Engineering: The Scaffold, provides a thorough update to the existing material, bringing together these two unique areas to give a perspective of the emerging therapeutic strategies for a wide audience. New coverage includes: Updated discussion of the importance of scaffolds in tissue engineering Exploration of cellular interactions at the nanoscale Complete range of fabrication processes capable of developing nanostructured scaffolds for regenerative engineering Applications of nanostructured scaffolds for neural, skin, cardiovascular, and musculoskeletal regenerative engineering FDA approval process of nanostructure scaffolds Products based on nanostructured scaffolds Due to the unique and tissue-mimic properties of the nanostructured scaffolds, the past five years have seen a tremendous growth in nanostructured materials for biological applications. The revised work presents the current state-of-the-art developments in nanostructured scaffolds for regenerative engineering.

Biomimetic biomaterials

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Publisher : Elsevier Inc. Chapters
ISBN 13 : 0128088176
Total Pages : 36 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Biomimetic biomaterials by : D. Campbell

Download or read book Biomimetic biomaterials written by D. Campbell and published by Elsevier Inc. Chapters. This book was released on 2013-09-30 with total page 36 pages. Available in PDF, EPUB and Kindle. Book excerpt: This chapter discusses recent developments of injectable biomimetic hydrogel systems found in soft tissue repair applications. It begins by introducing how biomimesis and biomaterials are related, and how tissue repair systems can be considered biomimetic. We introduce hydrogels by discussing their classification, synthesis and applications, then discuss how injectable biomimetic hydrogels have been investigated for use in soft tissue repair. Different approaches to the use of biomimetic hydrogels for soft tissue repair are covered, focusing on synthetic, non-biodegrable polymers. We include so-called conventional polymers and more biomimetic polymers. The chapter concludes with the likely future trends and highlights further reading materials.

Engineering of Elastomeric Biomaterials and Biomimicry of Extracellular Matrix for Soft Tissue Regeneration

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Publisher :
ISBN 13 :
Total Pages : 264 pages
Book Rating : 4.:/5 (974 download)

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Book Synopsis Engineering of Elastomeric Biomaterials and Biomimicry of Extracellular Matrix for Soft Tissue Regeneration by : Mary E. Wade

Download or read book Engineering of Elastomeric Biomaterials and Biomimicry of Extracellular Matrix for Soft Tissue Regeneration written by Mary E. Wade and published by . This book was released on 2016 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discoveries of new synthetic polymeric materials have become increasingly important in the field of biomedicine. Recent advancements in bio-functionalization strategies have led to innovation of biomimetic materials that can enhance tissue regeneration. Poly(ester urea)s are one unique set of materials comprised of amino acids and diols that are able to achieve tunable mechanical and degradation properties for a variety of tissue engineering applications. These materials can be functionalized with peptides utilizing an assortment of strategies in order to enhance cellular and tissue interactions. One alternative functionalization strategy under current investigation is combining decellularized extracellular matrix with poly(ester urea)s using engineering approaches such as electrospinning, melt-spinning, and 3D-printing. Our research into these techniques has provided interesting insights into the effects of processing on nanostructured scaffolds, and how molecular and scaffold structure can be tailored to overcome processing obstacles.We have also recently discovered a new series of elastomeric materials inspired by the chemical structure of rubber. These new polymers also exhibit tunable mechanical and degradation properties. We have tested these elastomers in vitro and in vivo and observed excellent cellular and tissue responses. Elastomers containing a degradable monomer in every copolymer repeat unit were capable of degrading within a period of 4 months in vivo while allowing for significant tissue infiltration and matrix regeneration. These two examples support the use of biomimicry for the design of novel materials, from molecular synthetic strategies to macromolecular scaffold design, and similar approaches will play a critical role in furthering the development of biomaterials for tissue regeneration.

Biomaterials in Tissue Engineering and Regenerative Medicine

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Publisher : Springer Nature
ISBN 13 : 9811600023
Total Pages : 587 pages
Book Rating : 4.8/5 (116 download)

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Book Synopsis Biomaterials in Tissue Engineering and Regenerative Medicine by : Birru Bhaskar

Download or read book Biomaterials in Tissue Engineering and Regenerative Medicine written by Birru Bhaskar and published by Springer Nature. This book was released on 2021-04-29 with total page 587 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book comprehensively explores the basic concepts and applications of biomaterials in tissue engineering and regenerative medicine. The book is divided into four sections; the first section deals with the basic concepts and different types of biomaterials used in tissue engineering. The second section discusses the functional requirements and types of materials that are used in developing state-of-the-art of scaffolds for tissue engineering applications. The third section presents the applications of biomaterials for hard and soft tissue engineering, as well as for specialized tissue engineering. The last section addresses the future prospects of nanobiomaterials, intelligent biomaterials, and 3D bioprinting biomaterials in tissue engineering and regenerative medicine. It also discusses various in vitro disease models for tissue bioengineering and regenerative medicine. As such, it offers a valuable resource for students, researchers, scientists, entrepreneurs, and medical/healthcare professionals.

Tissue Regeneration: Where Nano-structure Meets Biology

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Publisher : World Scientific
ISBN 13 : 9814494852
Total Pages : 546 pages
Book Rating : 4.8/5 (144 download)

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Book Synopsis Tissue Regeneration: Where Nano-structure Meets Biology by : Qing Liu

Download or read book Tissue Regeneration: Where Nano-structure Meets Biology written by Qing Liu and published by World Scientific. This book was released on 2014-01-03 with total page 546 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique volume presents the recent advances in tissue regeneration. The authors are all active researchers in their respective fields with extensive experiences. The focus of the book is on the use of stem cells and nano-structured biomaterials for tissue regeneration/tissue engineering. It includes the use of stem cells, naturally derived extracellular matrix (ECM), synthetic biomimetic nano-fibers, synthetic nano-structured ceramics and synthetic nano-structured polymer/ceramic composites that can help/promote tissue regeneration. Methods on how to produce these nano-structured biomaterials are also discussed in several chapters. Future challenges and perspectives in the field of regenerative medicine (tissue regeneration) are also discussed.

Bioactive Materials for Bone Regeneration

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Publisher : Academic Press
ISBN 13 : 0128135042
Total Pages : 252 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Bioactive Materials for Bone Regeneration by : Jiang Chang

Download or read book Bioactive Materials for Bone Regeneration written by Jiang Chang and published by Academic Press. This book was released on 2020-02-28 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioactive Materials for Bone Regeneration summarizes research advances on the topic, including sections on the characteristics of biomaterial-induced microenvironments, interactions of bioactive materials with stem cells and tissues, and the immunomodulatory microenvironment induced by biomaterials and its effects on osteogenesis. As the regeneration of large-size bone tissue defects represents a significant clinical challenge, this book demonstrates how new biomaterials with specific chemical and physical characteristics may interact with the host and create a unique micro-environment that actively facilitates stem cell differentiation along a specific lineage, thus stimulating tissue regeneration. Provides readers with the latest research developments in the fabrication techniques of bioactive materials for tissue regeneration and tissue engineering applications Presents the latest research advancements on how bioactive materials interact with the host and induce micro-environments for stem cell differentiation, immunomodulation and tissue regeneration Covers the methods, strategies, principle and mechanisms on constructing beneficial biomaterial microenvironments

Tissue Engineering Using Ceramics and Polymers

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Publisher : Elsevier
ISBN 13 : 0857097164
Total Pages : 743 pages
Book Rating : 4.8/5 (57 download)

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Book Synopsis Tissue Engineering Using Ceramics and Polymers by : Aldo R. Boccaccini

Download or read book Tissue Engineering Using Ceramics and Polymers written by Aldo R. Boccaccini and published by Elsevier. This book was released on 2014-06-11 with total page 743 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of Tissue Engineering Using Ceramics and Polymers comprehensively reviews the latest advances in this area rapidly evolving area of biomaterials science. Part one considers the biomaterials used for tissue engineering. It introduces the properties and processing of bioactive ceramics and glasses, as well as polymeric biomaterials, particularly biodegradable polymer phase nanocomposites. Part two reviews the advances in techniques for processing, characterization, and modeling of materials. The topics covered range from nanoscale design in biomineralization strategies for bone tissue engineering to microscopy techniques for characterizing cells to materials for perfusion bioreactors. Further, carrier systems and biosensors in biomedical applications are considered. Finally, part three looks at the specific types of tissue and organ regeneration, with chapters concerning kidney, bladder, peripheral nerve, small intestine, skeletal muscle, cartilage, liver, and myocardial tissue engineering. Important developments in collagen-based tubular constructs, bioceramic nanoparticles, and multifunctional scaffolds for tissue engineering and drug delivery are also explained. Tissue Engineering Using Ceramics and Polymers is a valuable reference tool for both academic researchers and scientists involved in biomaterials or tissue engineering, including the areas of bone and soft-tissue reconstruction and repair, and organ regeneration. Second edition comprehensively examines the latest advances in ceramic and polymers in tissue engineering Provides readers with general information on polymers and ceramics and looks at the processing, characterization, and modeling Reviews the latest research and advances in tissue and organ regeneration using ceramics and polymers

Handbook Of Biomimetics And Bioinspiration: Biologically-driven Engineering Of Materials, Processes, Devices, And Systems (In 3 Volumes)

Download Handbook Of Biomimetics And Bioinspiration: Biologically-driven Engineering Of Materials, Processes, Devices, And Systems (In 3 Volumes) PDF Online Free

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Publisher : World Scientific
ISBN 13 : 9814520276
Total Pages : 1462 pages
Book Rating : 4.8/5 (145 download)

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Book Synopsis Handbook Of Biomimetics And Bioinspiration: Biologically-driven Engineering Of Materials, Processes, Devices, And Systems (In 3 Volumes) by : Esmaiel Jabbari

Download or read book Handbook Of Biomimetics And Bioinspiration: Biologically-driven Engineering Of Materials, Processes, Devices, And Systems (In 3 Volumes) written by Esmaiel Jabbari and published by World Scientific. This book was released on 2014-04-29 with total page 1462 pages. Available in PDF, EPUB and Kindle. Book excerpt: Global warming, pollution, food and water shortage, cyberspace insecurity, over-population, land erosion, and an overburdened health care system are major issues facing the human race and our planet. These challenges have presented a mandate to develop “natural” or “green” technologies using nature and the living system as a guide to rationally design processes, devices, and systems. This approach has given rise to a new paradigm, one in which innovation goes hand-in-hand with less waste, less pollution, and less invasiveness to life on earth. Bioinspiration has also led to the development of technologies that mimic the hierarchical complexity of biological systems, leading to novel highly efficient, more reliable multifunctional materials, devices, and systems that can perform multiple tasks at one time. This multi-volume handbook focuses on the application of biomimetics and bioinspiration in medicine and engineering to produce miniaturized multi-functional materials, devices, and systems to perform complex tasks. Our understanding of complex biological systems at different length scales has increased dramatically as our ability to observe nature has expanded from macro to molecular scale, leading to the rational biologically-driven design to find solution to technological problems in medicine and engineering.The following three-volume set covers the fields of bioinspired materials, electromechanical systems developed from concepts inspired by nature, and tissue models respectively.The first volume focuses on the rational design of nano- and micro-structured hierarchical materials inspired by the relevant characteristics in living systems, such as the self-cleaning ability of lotus leaves and cicadas' wings; the superior walking ability of water striders; the anti-fogging function of mosquitoes' eyes; the water-collecting ability of Namib Desert Beetles and spider silk; the high adhesivity of geckos' feet and rose petals; the high adhesivity of mussels in wet aquatic environments; the anisotropic wetting of butterflies' wings; the anti-reflection capabilities of cicadas' wings; the self-cleaning functionality of fish scales; shape anisotropy of intracellular particles; the dielectric properties of muscles; the light spectral characteristics of plant leaves; the regeneration and self-healing ability of earthworms; the self-repairing ability of lotus leaves; the broadband reflectivity of moths' eyes; the multivalent binding, self-assembly and responsiveness of cellular systems; the biomineral formation in bacteria, plants, invertebrates, and vertebrates; the multi-layer structure of skin; the organization of tissue fibers; DNA structures with metal-mediated artificial base pairs; and the anisotropic microstructure of jellyfish mesogloea. In this volume, sensor and microfluidic technologies combined with surface patterning are explored for the diagnosis and monitoring of diseases. The high throughput combinatorial testing of biomaterials in regenerative medicine is also covered.The second volume presents nature-oriented studies and developments in the field of electromechanical devices and systems. These include actuators and robots based on the movement of muscles, algal antenna and photoreception; the non-imaging light sensing system of sea stars; the optical system of insect ocellus; smart nanochannels and pumps in cell membranes; neuromuscular and sensory devices that mimic the architecture of peripheral nervous system; olfaction-based odor sensing; cilia-mimetic microfluidic systems; the infrared sensory system of pyrophilous insects; ecologically inspired multizone temperature control systems; cochlea and surface acoustic wave resonators; crickets' cercal system and flow sensing abilities; locusts' wings and flapping micro air vehicles; the visual motion sensing of flying insects; hearing aid devices based on the human cochlea; the geometric perception of tortoises and pigeons; the organic matter sensing capability of cats and dogs; and the silent flight of rats. The third volume features engineered models of biological tissues. These include engineered matrices to mimic cancer stem cell niches; in vitro models for bone regeneration; models of muscle tissue that enable the study of cardiac infarction and myopathy; 3D models for the differentiation of embryonic stem cells; bioreactors for in vitro cultivation of mammalian cells; human lung, liver and heart tissue models; topographically-defined cell culture models; ECM mimetic tissue printing; biomimetic constructs for regeneration of soft tissues; and engineered constructs for the regeneration of musculoskeletal and corneal tissue.This three-volume set is a must-have for anyone keen to understand the complexity of biological systems and how that complexity can be mimicked to engineer novel materials, devices and systems to solve pressing technological challenges of the twenty-first century.Key Features:The only handbook that covers all aspects of biomimetics and bioinspiration, including materials, mechanics, signaling and informaticsContains 248 colored figures

Mussel-inspired Biomimetic Materials for Tissue-engineering Scaffold and Controlled Drug Release

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Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (134 download)

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Book Synopsis Mussel-inspired Biomimetic Materials for Tissue-engineering Scaffold and Controlled Drug Release by : Junzi Jr Jiang

Download or read book Mussel-inspired Biomimetic Materials for Tissue-engineering Scaffold and Controlled Drug Release written by Junzi Jr Jiang and published by . This book was released on 2015 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thesis reports three projects on mussel-inspired biomimetic materials based on dopamine crosslinkers. First, polyethylene glycol diacrylate (PEGDA) hydrogels with excellent cell attachment and tunable stiffness was fabricated based on this novel crosslinker. In vitro tests proved that the designed hydrogels had excellent cell adhesion, suggesting the developed hydrogels are promising for applications in tissue engineering. Second, dopamine crosslinker-conjugated gelatin-polycparolactone (PCL) nanofibrous sheet was developed. The sheet was then employed successfully to treat stomach incision without suture during surgery, showing promising to deal with treatments of fragile tissues and to avoid suture caused stress concentration. Third, a facile strategy to wrap cell into a tissue-engineered scaffold was developed, which is a self-rolling and conductive dopamine-based film. The RTPCR test indicated that cells have higher level of differentiation with higher concentration of MWCNTs. This suggests that the self-rolling conductive WCNT-dopamine-PEG hydrogel is a promising scaffolding material for bone regeneration.

Biomimetic, Bioresponsive, and Bioactive Materials

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 0470056711
Total Pages : 250 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Biomimetic, Bioresponsive, and Bioactive Materials by : Matteo Santin

Download or read book Biomimetic, Bioresponsive, and Bioactive Materials written by Matteo Santin and published by John Wiley & Sons. This book was released on 2012-04-10 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: The accessible introduction to biomaterials and their applications in tissue replacement, medical devices, and more Molecular and cell biology is being increasingly integrated into the search for high-performance biomaterials and biomedical devices, transforming a formerly engineering- and materials science–based field into a truly interdisciplinary area of investigation. Biomimetic, Bioresponsive, and Bioactive Materials presents a comprehensive introduction to biomaterials, discussing how they are selected, designed, and modified for integration with living tissue and how they can be utilized in the development of medical devices, orthopedics, and other related areas. Examining the physico chemical properties of widely used biomaterials and their uses in different clinical fields, the book explores applications including soft and hard tissue replacement; biointeractive metals, polymers, and ceramics; and in vitro, in vivo, and ex vivo biocompatibility tests and clinical trials. The book critically assesses the clinical level of research in the field, not only presenting proven research, but also positing new avenues of exploration. Biomimetic, Bioresponsive, and Bioactive Materials contains everything needed to get a firm grasp on materials science, fast. Written in an accessible style and including practice questions that test comprehension of the material covered in each chapter, the book is an invaluable tool for students as well as professionals new to the field.