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Biochemie Hoch2 Clinicalkey Edition
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Book Synopsis Advances in Medicinal Chemistry by : B.E. Maryanoff
Download or read book Advances in Medicinal Chemistry written by B.E. Maryanoff and published by Elsevier. This book was released on 1999-04-01 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 4 of Advances in Medicinal Chemistry is comprised of six chapters on a wide range of topics in medicinal chemistry, including molecular modeling, structure-based drug design, organic synthesis, peptide conformational analysis, biological assessment, structure-activity correlation, and lead optimization. Chapter 1 presents an account about amino acid-based peptide mimetics corresponding to b-turn, loop, helical motifs in proteins as a probe of ligand-receptor and ligand-enzyme molecular interactions. Chapter 2 addresses new facets of the medicinal chemistry of the important anticancer drug Taxol® (paclitaxel). Chapter 3 relates an account of the search for new drugs for the treatment of malaria based on the natural product artemisinin. Chapter 4 applies computational chemistry to the evaluation of compound libraries for biological testing. Chapter 5 describes the construction of a 3-dimensional molecular model of the human thrombin receptor, the first protease-activated G-protein coupled receptor (PAR-1), as a means to explore the intermolecular contacts involved in agonist peptide recognition. Finally, Chapter 6 describes the research conducted at Merck on inhibitors of farnesyl transferase as a potential treatment for human cancers.
Download or read book Receptors written by Clare Stanford and published by . This book was released on 2023 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecules can only enter cells via receptors, and thus are the subject of much attention. This new edition is a comprehensive review of new methods that can be used for studying receptors and how each technique can be used on different receptor types.
Book Synopsis Murder, Magic, and Medicine by : John Mann
Download or read book Murder, Magic, and Medicine written by John Mann and published by Oxford University Press, USA. This book was released on 1994 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: This absorbing account of the evolution of modern medicine from its roots in folk medicine will entertain and inform both scientist and general reader alike. It explains the chemical basis of pharmacology, and provides a fascinating description of how the use and abuse of natural products in various societies throughout the ages has led to the development of many of the drugs we now take for granted.
