Biochemical And Neurophysiological Correlation Of Centrally Action Drugs

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Biochemical and Neurophysiological Correlation of Centrally Acting Drugs

Author : E. Trabucchi
Publisher : Elsevier
ISBN 13 : 1483185389
Total Pages : 297 pages
Book Rating : 4.4/5 (831 download)

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Book Synopsis Biochemical and Neurophysiological Correlation of Centrally Acting Drugs by : E. Trabucchi

Download or read book Biochemical and Neurophysiological Correlation of Centrally Acting Drugs written by E. Trabucchi and published by Elsevier. This book was released on 2013-10-22 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: Section on Pharmacology of the International Union of Physiological Sciences (SEPHAR), Proceedings of the Second International Pharmacological Meeting, August 20-23, 1963, Volume 2: Biochemical and Neurophysiological Correlation of Centrally Acting Drugs focuses on the composition, reactions, and applications of centrally acting drugs. The selection first offers information on the physiology of striopallidum in relation to extrapyramidal function and disorders and actions of dopa and dopamine in relation to function of the central nervous system. Discussions focus on correlation of behavioral and clinical states with metabolism of dopamine, functions of dopamine in the brain, and the central pharmacology of dopamine. The text then examines the role of brain dopamine (3-hydroxytyramine) in Parkinsonism, including behavior of dopamine in the extrapyramidal centers in patients with Parkinson's disease; brain dopamine and the extrapyramidal symptomatology of Parkinson's disease; and parallelism between Parkinson's disease and the Parkinson-like state induced by reserpine in man. The publication ponders on pharmacological studies on tremorine and metabolism of tremorine. The manuscript also takes a look at the contribution on the pathophysiology of intentional tremor; failure of Antiparkinson drugs to antagonize hypothermia in tremorine-treated rats; and significance of dopamine in psychomotor stimulant action. The selection is a dependable source of data for readers interested in centrally acting drugs.

Biochemical and Neurophysiological Correlation of Centrally Acting Drugs

Author : E. Trabucchi
Publisher :
ISBN 13 :
Total Pages : 304 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis Biochemical and Neurophysiological Correlation of Centrally Acting Drugs by : E. Trabucchi

Download or read book Biochemical and Neurophysiological Correlation of Centrally Acting Drugs written by E. Trabucchi and published by . This book was released on 1964 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Psychopharmacology Abstracts

Author :
Publisher :
ISBN 13 :
Total Pages : 874 pages
Book Rating : 4.3/5 (243 download)

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Book Synopsis Psychopharmacology Abstracts by :

Download or read book Psychopharmacology Abstracts written by and published by . This book was released on 1965 with total page 874 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Physico-Chemical Aspects of Drug Action

Author : E. J. Ariëns
Publisher : Elsevier
ISBN 13 : 1483152693
Total Pages : 397 pages
Book Rating : 4.4/5 (831 download)

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Book Synopsis Physico-Chemical Aspects of Drug Action by : E. J. Ariëns

Download or read book Physico-Chemical Aspects of Drug Action written by E. J. Ariëns and published by Elsevier. This book was released on 2017-05-17 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: Physico-Chemical Aspects of Drug Action, Volume 7 covers topics on drug kinetics and the overall physicochemical properties of the drug in relation therewith, and the physicochemical aspects of the drug-receptor interaction, putting emphasis on receptor mechanisms and specific properties required for certain types of drugs in this respect. The book starts with some contributions dealing with various general aspects of drug kinetics followed by some contributions dealing with the relationship between certain physicochemical properties of drug molecules and their action. The text describes the pharmacokinetics and dose-concentration relationships; the time course of the biological response to drugs; and the empirical equations for correlating biological efficiency of organic compounds. The text also describes molecular basis for the action of chemotherapeutic drugs; the structure-activity studies on sulphonamides; and the water extrusion hypothesis. The mathematical treatment of two-point attachment between drug and receptor; the molecular properties and biological activity of catecholamines and certain related compounds; and the structure-activity relationships of diarylcarbinolethers are also considered. The book further tackles quantum mechanically-derived electronic distributions in the conformers of 2-pam; and the molecular basis for the action of certain drugs in the central nervous system. Pharmacologists and chemists will find the book invaluable.

International Directory of Investigators in Psychopharmacology

Author :
Publisher :
ISBN 13 :
Total Pages : 454 pages
Book Rating : 4.:/5 (3 download)

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Book Synopsis International Directory of Investigators in Psychopharmacology by :

Download or read book International Directory of Investigators in Psychopharmacology written by and published by . This book was released on 1972 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Caffeine in Food and Dietary Supplements

Author : Leslie A. Pray
Publisher :
ISBN 13 : 9780309297493
Total Pages : 0 pages
Book Rating : 4.2/5 (974 download)

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Book Synopsis Caffeine in Food and Dietary Supplements by : Leslie A. Pray

Download or read book Caffeine in Food and Dietary Supplements written by Leslie A. Pray and published by . This book was released on 2014 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Caffeine in Food and Dietary Supplements is the summary of a workshop convened by the Institute of Medicine in August 2013 to review the available science on safe levels of caffeine consumption in foods, beverages, and dietary supplements and to identify data gaps. Scientists with expertise in food safety, nutrition, pharmacology, psychology, toxicology, and related disciplines; medical professionals with pediatric and adult patient experience in cardiology, neurology, and psychiatry; public health professionals; food industry representatives; regulatory experts; and consumer advocates discussed the safety of caffeine in food and dietary supplements, including, but not limited to, caffeinated beverage products, and identified data gaps. Caffeine, a central nervous stimulant, is arguably the most frequently ingested pharmacologically active substance in the world. Occurring naturally in more than 60 plants, including coffee beans, tea leaves, cola nuts and cocoa pods, caffeine has been part of innumerable cultures for centuries. But the caffeine-in-food landscape is changing. There are an array of new caffeine-containing energy products, from waffles to sunflower seeds, jelly beans to syrup, even bottled water, entering the marketplace. Years of scientific research have shown that moderate consumption by healthy adults of products containing naturally-occurring caffeine is not associated with adverse health effects. The changing caffeine landscape raises concerns about safety and whether any of these new products might be targeting populations not normally associated with caffeine consumption, namely children and adolescents, and whether caffeine poses a greater health risk to those populations than it does for healthy adults. This report delineates vulnerable populations who may be at risk from caffeine exposure; describes caffeine exposure and risk of cardiovascular and other health effects on vulnerable populations, including additive effects with other ingredients and effects related to pre-existing conditions; explores safe caffeine exposure levels for general and vulnerable populations; and identifies data gaps on caffeine stimulant effects.

Immunopharmacology

Author : H. O. Schild
Publisher : Elsevier
ISBN 13 : 1483150429
Total Pages : 178 pages
Book Rating : 4.4/5 (831 download)

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Book Synopsis Immunopharmacology by : H. O. Schild

Download or read book Immunopharmacology written by H. O. Schild and published by Elsevier. This book was released on 2017-01-31 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunopharmacology is the 11th volume of the proceedings of the Third International Pharmacological Meeting held at Sao Paulo, Brazil on July 26, 1966. The volume covers papers that deal with immunoglobulins responsible for hypersensitivity reactions and with the mechanisms of these reactions; pharmacological mediators of immediate and delayed hypersensitivity; Arthus reactions; and soluble factors released by the action of antigen on sensitized lymphocytes. The book concludes with a single paper on the subject of penicillin allergy. Immunologists and pharmacologists will find the volume invaluable.

Pharmacology of Antimuscarinic Agents

Author : Laszlo Gyermek
Publisher : CRC Press
ISBN 13 : 9780849385599
Total Pages : 526 pages
Book Rating : 4.3/5 (855 download)

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Book Synopsis Pharmacology of Antimuscarinic Agents by : Laszlo Gyermek

Download or read book Pharmacology of Antimuscarinic Agents written by Laszlo Gyermek and published by CRC Press. This book was released on 1997-11-25 with total page 526 pages. Available in PDF, EPUB and Kindle. Book excerpt: The theoretical and practical significance of antimuscarinic drugs is more obvious today than ever before. Antimuscarinics have helped to explore the pathomechanisms of of Alzheimer's disease, and to treat the symptoms of Parkinson's, cardiovascular problems, gastrointestinal diseases, and even nerve gas poisoning. No other drug class can claim as long a history with so many therapeutic applications, yet the most significant developments in this broad chapter of pharmacology come from the discovery of different muscarinic receptor sites in the peripheral and central nervous system and from the availability of many new selective agents, notably antagonists, for these different receptor types. Pharmacology of Antimuscarinic Agents, written by an expert in anesthesiology and drug research, focuses on the basic principles of antimuscarinic drugs, their therapeutic value, how they work, and what versions are now available in the U.S. and abroad. This is the first time in decades an author has reviewed historical and current literature to present a comprehensive, standard reference on the antimuscarinic family.

Biochemical Factors Concerned in the Functional Activity of the Nervous System

Author : D. Richter
Publisher : Elsevier
ISBN 13 : 1483138488
Total Pages : 239 pages
Book Rating : 4.4/5 (831 download)

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Book Synopsis Biochemical Factors Concerned in the Functional Activity of the Nervous System by : D. Richter

Download or read book Biochemical Factors Concerned in the Functional Activity of the Nervous System written by D. Richter and published by Elsevier. This book was released on 2013-10-22 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biochemical Factors Concerned in the Functional Activity of the Nervous System presents the biological aspects concerned in the functional activity of the nervous system. This book covers several interesting topics concerning the central nervous system, including phospholipids, RNA synthesis, nerve impulse flow, and nerve growth factor. Comprised of 213 chapters, this book begins with an overview of the electron micrographs of calcium–ATP–phospholipid complexes. This text then examines the biochemical and histochemical studies on sectioned rat spinal cords, which demonstrated two types of monoamine-reducing drugs. Other chapters consider the diversity of antagonistic relations between the thiamine derivatives and vitamin B6, which is manifested by changes in the glutamate–GABA, histidine–histamine, tryptophan–serotonin, and tyrosine–noradrenaline systems. This book discusses as well the influence of a conditioned avoidance training experience on the incorporation of radioactive uridine into the RNA of mouse brain. The final chapter deals with the amino acid-incorporating activity of cerebral polyribosomes. This book is a valuable resource for biochemists, neurologists, pharmacologists, and biophysicists.

Drugs and Enzymes

Author : Bernard B. Brodie
Publisher : Elsevier
ISBN 13 : 1483223515
Total Pages : 519 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Drugs and Enzymes by : Bernard B. Brodie

Download or read book Drugs and Enzymes written by Bernard B. Brodie and published by Elsevier. This book was released on 2013-10-22 with total page 519 pages. Available in PDF, EPUB and Kindle. Book excerpt: Second International Pharmacological Meeting, Volume 4: Drugs and Enzymes is a collection of papers presented at the Second International Pharmacological Meeting on August 20-23, 1963. This volume is organized into two sections encompassing 41 chapters. The first section discusses the relationship between biochemical effects of drugs in vitro and their pharmacological effect in vivo. This section specifically examines the correlation between the action of substances on isolated smooth muscle and on the central nervous system, as well as the behavior of a centrally-acting drug and enzyme in the ion movement in the system. The second section surveys the biochemical mechanisms of drug toxicity. Considerable chapters in this section are devoted to the effect of drug toxicity, such as altered drug metabolism, enzyme induction, morphological changes, hepatic effects, and photosensitivity. This book will prove useful to pharmacologists, neurologists, biochemists, and researchers who are interested the fields of drugs and drug toxicity.

Pharmacological and Biophysical Agents and Behavior

Author : Ernest Furchtgott
Publisher : Academic Press
ISBN 13 : 1483273830
Total Pages : 415 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Pharmacological and Biophysical Agents and Behavior by : Ernest Furchtgott

Download or read book Pharmacological and Biophysical Agents and Behavior written by Ernest Furchtgott and published by Academic Press. This book was released on 2013-09-03 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmacological and Biophysical Agents and Behavior is a compendium of papers that discusses the effects of radiations, drugs, or other similar agents on human behavior. This collection is a reference guide to the analysis of behavioral effects of other agents such as those produced by radiation, hypoxia. or thermal stress. One paper reviews the effects of material or corpuscular radiations and electromagnetic radiations that even low doses occurring during the prenatal stage can result in permanent behavioral deficits. Another paper notes that any hazards resulting from the increasing use of microwave generating devices should be investigated as the possibility of such subtle hazards can affect learning, emotional, and personality behaviors. One paper analyzes the chronic effects of thermal stress on behavior, as well as those of convulsants (strychnine) and general stimulants (caffeine). The book also reviews the effects of sympathomimetic amines on emotional behavior, sleep, activity, food intake, and temperature regulation. This compendium can prove beneficial for pharmacologists, psychiatrists, psychologists, students, and professors in related disciplines.

Mechanisms of Drug Toxicity

Author : H. Rašková
Publisher : Elsevier
ISBN 13 : 1483157202
Total Pages : 113 pages
Book Rating : 4.4/5 (831 download)

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Book Synopsis Mechanisms of Drug Toxicity by : H. Rašková

Download or read book Mechanisms of Drug Toxicity written by H. Rašková and published by Elsevier. This book was released on 2013-10-22 with total page 113 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mechanisms of Drug Toxicity, Volume 4 presents the proceedings of the 3rd International Pharmacological Meeting held in Sao Paulo, Brazil in 1966. The book discusses the drug-induced pathobiotic effects; the mechanisms of adverse reactions; and enzyme induction in the mechanism of chronic toxicity. The text also describes the influence of inducing substances on the growth of liver and microsomal electron transport systems; the quantitative aspects of chronic toxicity; and the facts and fallacies in predicting drug effects in human.

Salt and Water Balance

Author : K. H. Beyer
Publisher : Elsevier
ISBN 13 : 148315047X
Total Pages : 121 pages
Book Rating : 4.4/5 (831 download)

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Book Synopsis Salt and Water Balance by : K. H. Beyer

Download or read book Salt and Water Balance written by K. H. Beyer and published by Elsevier. This book was released on 2013-10-08 with total page 121 pages. Available in PDF, EPUB and Kindle. Book excerpt: Salt and Water Balance, Volume 8 presents the proceedings of the 3rd International Pharmacological Meeting, held in Sao Paulo, Brazil, on July 24–30, 1966. This book features the modulation of renal control of electrolyte and water balance, which is the most effective approach of handling most clinical problems wherein fluid retention needs to be reduced. Comprised of 10 chapters, this compilation of papers starts with an overview of the diuretic agents that are effective diuretic therapy. This text then describes the active transport, which proceeds at the expense of energy against the combined chemical and electrical gradients in the case of electrolytes. Other chapters consider the historical importance in therapy and the mechanisms of action of mercurial diuretics. This book discusses as well the complications and unwanted side effects of diuretic therapy. The final chapter deals with the hemodynamic mechanisms and their possible influence on the tubular function. This book is a valuable resource for physicians, health care professionals, and patients.

Advances in Pharmacology

Author :
Publisher : Academic Press
ISBN 13 : 0080580955
Total Pages : 336 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Advances in Pharmacology by :

Download or read book Advances in Pharmacology written by and published by Academic Press. This book was released on 1967-01-01 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Pharmacology

Pharmacology of Pain

Author : R. K. S. Lim
Publisher : Elsevier
ISBN 13 : 1483155285
Total Pages : 261 pages
Book Rating : 4.4/5 (831 download)

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Book Synopsis Pharmacology of Pain by : R. K. S. Lim

Download or read book Pharmacology of Pain written by R. K. S. Lim and published by Elsevier. This book was released on 2016-07-29 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmacology of Pain, Volume 9 presents the proceedings of the 3rd International Pharmacological Meetings held in Sao Paulo in 1966. The book includes papers on the mediators of pain; proteolytic enzymes as mediators of pain; and desensitization with capsaicin and related acylamides as a tool for studying the function of pain receptors. The text also covers the sensitization of nociceptors by 5-hydroxytryptamine in man; the possible role of serotonin in affective component of pain behavioral reaction in the rat; and the use of pain induced functional impairment for assessing analgesic action. Papers on the clinical pharmacology of analgesics and analgesic antagonists; behavioral mechanisms of human pain; and central nervous mechanisms involved in pain and analgesia are also considered. The book further tackles the neuropharmacology of pain and analgesia; the interrelationship of cortical and subcortical pain systems; and the interaction of fast- and slow-conducting fiber systems involved in pain and analgesia.

Proceedings

Author :
Publisher :
ISBN 13 :
Total Pages : 144 pages
Book Rating : 4.0/5 ( download)

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Book Synopsis Proceedings by :

Download or read book Proceedings written by and published by . This book was released on 1966 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Pathways of Addiction

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309055334
Total Pages : 330 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Pathways of Addiction by : Institute of Medicine

Download or read book Pathways of Addiction written by Institute of Medicine and published by National Academies Press. This book was released on 1996-11-01 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug abuse persists as one of the most costly and contentious problems on the nation's agenda. Pathways of Addiction meets the need for a clear and thoughtful national research agenda that will yield the greatest benefit from today's limited resources. The committee makes its recommendations within the public health framework and incorporates diverse fields of inquiry and a range of policy positions. It examines both the demand and supply aspects of drug abuse. Pathways of Addiction offers a fact-filled, highly readable examination of drug abuse issues in the United States, describing findings and outlining research needs in the areas of behavioral and neurobiological foundations of drug abuse. The book covers the epidemiology and etiology of drug abuse and discusses several of its most troubling health and social consequences, including HIV, violence, and harm to children. Pathways of Addiction looks at the efficacy of different prevention interventions and the many advances that have been made in treatment research in the past 20 years. The book also examines drug treatment in the criminal justice setting and the effectiveness of drug treatment under managed care. The committee advocates systematic study of the laws by which the nation attempts to control drug use and identifies the research questions most germane to public policy. Pathways of Addiction provides a strategic outline for wise investment of the nation's research resources in drug abuse. This comprehensive and accessible volume will have widespread relevanceâ€"to policymakers, researchers, research administrators, foundation decisionmakers, healthcare professionals, faculty and students, and concerned individuals.