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Benzodiazepine Addiction From Lab To Street
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Book Synopsis Benzodiazepine Addiction: From Lab to Street by : Lais F. Berro
Download or read book Benzodiazepine Addiction: From Lab to Street written by Lais F. Berro and published by Frontiers Media SA. This book was released on 2023-10-20 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: Benzodiazepine-type drugs (benzodiazepines and newer non-benzodiazepines, such as “Z drugs”) are important therapeutic tools in psychiatric medicine, being among the most highly prescribed psychiatric medications. Despite their clinical usefulness, benzodiazepines also induce several unwanted side effects, including abuse and dependence. In fact, the misuse and abuse of benzodiazepines have increased dramatically in recent years, with overdose deaths due to the combination of benzodiazepines and opioids reaching an all-time high, emphasizing that benzodiazepine abuse is cause for concern. Critically, no approved and broadly effective pharmacotherapy exists for the treatment of benzodiazepine misuse/use disorder.
Book Synopsis Worse Than Heroin by : E. Robert Mercer
Download or read book Worse Than Heroin written by E. Robert Mercer and published by Lulu.com. This book was released on 2008-07-01 with total page 203 pages. Available in PDF, EPUB and Kindle. Book excerpt: The most pervasive drug problem in the world is not heroin, not crack, not crystal meth, not pot, not any of the illicit drugs. Combined with the brutal nature of its addiction and the time and difficulty involved in withdrawing, a legal classification of drugs is by far the worst. Given their legal status and widespread use, benzodiazepines are secretly taking away the lives of Americans and people in other western cultures as we increasingly turn to pills to heal us. Commonly known as tranquillizers, the effects of these highly addictive prescription drugs are ghastly. Withdrawing from them can be extraordinarily difficult, far beyond description. This is the true story of one man's journey through dozens of relentless, horrific withdrawal symptoms to renewed health. These drugs are worse than heroin.
Book Synopsis Blood Orange Night by : Melissa Bond
Download or read book Blood Orange Night written by Melissa Bond and published by Simon and Schuster. This book was released on 2022-06-14 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain on Fire meets High Achiever in this “page-turner memoir chronicling a woman’s accidental descent into prescription benzodiazepine dependence—and the life-threatening impacts of long-term use—that chills to the bone” (Nylon). As Melissa Bond raises her infant daughter and a special-needs one-year-old son, she suffers from unbearable insomnia, sleeping an hour or less each night. She loses her job as a journalist (a casualty of the 2008 recession), and her relationship with her husband grows distant. Her doctor casually prescribes benzodiazepines—a family of drugs that includes Xanax, Valium, Klonopin, Ativan—and increases her dosage regularly. Following her doctor’s orders, Melissa takes the pills night after night until her body begins to shut down. Only when she collapses while holding her daughter does Melissa learn that her doctor—like so many others—has over-prescribed the medication and quitting cold turkey could lead to psychosis or fatal seizures. Benzodiazepine addiction is not well studied, and few experts know how to help Melissa as she begins the months-long process of tapering off the pills without suffering debilitating, potentially deadly consequences. Each page thrums with the heartbeat of Melissa’s struggle—how many hours has she slept? How many weeks old are her babies? How many milligrams has she taken? Her propulsive writing crescendos to a fever pitch as she fights for her health and her ability to care for her children. “Propulsive, poetic” (Shelf Awareness), and immersive, this “vivid chronicle of suffering” (Kirkus Reviews) and redemption shines a light on the prescription benzodiazepine epidemic as it reaches a crisis point in this country.
Download or read book The Benzodiazepines written by J. Marks and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 95 pages. Available in PDF, EPUB and Kindle. Book excerpt: The story of the benzodiazepines is a fascinating one: the synthesis of a long series of inert compounds and the abandonment of the project: months later, the renewal of the project and the discovery that this compound R05-0690 (Librium ®) was a sedative and muscle relaxant in laboratory animals: the recognition that its postulated structure was wrong and that it was in fact a member of an entirely new chemical class: the excitement caused by the discovery of the powerful taming effect of the drug in wild animals: the even greater excitement in medical circles when its dramatic anxiety relieving effects were cstablished in humans: the subsequent enormous world wide usc of drugs of the benzodiazepine group. I have reason to know the story well for during that period I worked in various capacities in research, marketing and manage ment in the British subsidiary of F. Hoffmann-Ia Roche. It was during this period that I became interested in whether dependence on benzodiazepines could occur and if so to what extent, but felt that this could be examined best from outside the concern. Having now retired from Roche back to academic medicine I have taken the opportunity to examine and analyse the evidence.
Author :American Psychiatric Association Publisher :American Psychiatric Pub ISBN 13 :9780890422281 Total Pages :132 pages Book Rating :4.4/5 (222 download)
Book Synopsis Benzodiazepine Dependence, Toxicity, and Abuse by : American Psychiatric Association
Download or read book Benzodiazepine Dependence, Toxicity, and Abuse written by American Psychiatric Association and published by American Psychiatric Pub. This book was released on 1990 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, patients, lay publications, and consumer groups have expressed concern about whether benzodiazepines are overprescribed. Psychiatrists have raised questions about the potential for these medications -- especially some of the newer, high-potency, short half-life compounds -- to produce serious side effects as well as to induce drug dependence. Benzodiazepine Dependence, Toxicity, and Abuse provides clinicians with a review of the available information on the potential hazards of benzodiazepine treatment and offers suggestions for the rational prescription of these medications.
Book Synopsis The Benzodiazepines Crisis by : John Peppin
Download or read book The Benzodiazepines Crisis written by John Peppin and published by Oxford University Press, USA. This book was released on 2021 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: Misused, abused, diverted, and counterfeited, benzodiazepines have serious potential for substance use disorder, and are among the leading causes of drug-related overdose deaths. Evidence indicates that prolonged use of benzodiazepines causes a wide range of adverse reactions, and withdrawal can be particularly challenging. Nevertheless, these negative aspects have yet to be thoroughly addressed within the medical community and remain virtually unknown to patients. This book offers an in-depth discussion of the downsides of this overused class of drugs and calls for their rational and dramatically reduced usage.
Download or read book Calming the Brain written by Adam Doble and published by CRC Press. This book was released on 2020-09-08 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the entire field of research in the area of minor tranquillizers and its application to current clinical practice in the treatment of anxiety and insomnia. These drugs are principally the benzodiazepines and related drugs with a similar mechanism of action, such as zolpidem and zopiclone. The molecular mechanism of action of benzodiazepines is described, focussing on the interaction of these drugs with the different isoform of the GABAA^O >receptor, and the consequences of this for brain function. Recent advances in this knowledge have provided a framework for defining the physiochemical nature of the interaction between such drugs and their receptor protein, and thus pave the way for the design of new anxiolytic and hypnotic drugs. The animal models available for evaluating the potential of such new therapeutic agents in the treatment of anxiety and insomnia are discussed. Furthermore, understanding of the physiological regulation of the GABAA receptor may provide insights into the aetiopathology of these diseases. The clinical use of benzodiazepines and related drugs in the treatment of anxiety, insomnia, epilepsy and as anaesthetics are explored. The advantages and limitations of such treatments are discussed, and the impact of drugs evaluated. A chapter is devoted to the issue of independence, the clinical pertinence of tolerence and dependence, and evaluates treatment options that may minimise the risk of dependence.
Book Synopsis Benzodiazepine Addiction, Withdrawal and Recovery by :
Download or read book Benzodiazepine Addiction, Withdrawal and Recovery written by and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Ray Nimmo presents information on benzodiazepine addiction, withdrawal, and recovery. Benzodiazepines are tranquilizers, or central nervous system depressants. The five primary effects of benzodiazepines include hypnotic, anxiolytic, anti-seizure, muscle relaxant, and amnesic. Nimmo highlights a FAQ section, side effects of the drugs, withdrawal symptoms, news about the drugs, and treatment of benzodiazepine dependence.
Download or read book Drug Dealer, MD written by Anna Lembke and published by JHU Press. This book was released on 2016-11-15 with total page 187 pages. Available in PDF, EPUB and Kindle. Book excerpt: The disturbing connection between well-meaning physicians and the prescription drug epidemic. Three out of four people addicted to heroin probably started on a prescription opioid, according to the director of the Centers for Disease Control and Prevention. In the United States alone, 16,000 people die each year as a result of prescription opioid overdose. But perhaps the most frightening aspect of the prescription drug epidemic is that it’s built on well-meaning doctors treating patients with real problems. In Drug Dealer, MD, Dr. Anna Lembke uncovers the unseen forces driving opioid addiction nationwide. Combining case studies from her own practice with vital statistics drawn from public policy, cultural anthropology, and neuroscience, she explores the complex relationship between doctors and patients, the science of addiction, and the barriers to successfully addressing drug dependence and addiction. Even when addiction is recognized by doctors and their patients, she argues, many doctors don’t know how to treat it, connections to treatment are lacking, and insurance companies won’t pay for rehab. Full of extensive interviews—with health care providers, pharmacists, social workers, hospital administrators, insurance company executives, journalists, economists, advocates, and patients and their families—Drug Dealer, MD, is for anyone whose life has been touched in some way by addiction to prescription drugs. Dr. Lembke gives voice to the millions of Americans struggling with prescription drugs while singling out the real culprits behind the rise in opioid addiction: cultural narratives that promote pills as quick fixes, pharmaceutical corporations in cahoots with organized medicine, and a new medical bureaucracy focused on the bottom line that favors pills, procedures, and patient satisfaction over wellness. Dr. Lembke concludes that the prescription drug epidemic is a symptom of a faltering health care system, the solution for which lies in rethinking how health care is delivered.
Book Synopsis Seminars in Addiction Psychiatry by : Ed Day
Download or read book Seminars in Addiction Psychiatry written by Ed Day and published by Cambridge University Press. This book was released on 2021-11-04 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive coverage of the theory, practical understanding and management of the psychiatric aspects of drug and alcohol use and dependence.
Download or read book Benzodiazepines written by Ian Hindmarch and published by John Wiley & Sons. This book was released on 1990 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: A collection of papers covering current concepts in the field of benzodiazepines. The contributors look at biological, clinical and social perspectives of their use and misuse in areas such as neuropsychiatry, general practice and anaesthesia.
Book Synopsis Magnesium in the Central Nervous System by : Robert Vink
Download or read book Magnesium in the Central Nervous System written by Robert Vink and published by University of Adelaide Press. This book was released on 2011 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.
Book Synopsis The GABA Receptors by : Salvatore J. Enna
Download or read book The GABA Receptors written by Salvatore J. Enna and published by Springer Science & Business Media. This book was released on 2007-11-17 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Gaba Receptors, Third Edition, presents a critical appraisal of our current understanding of the molecular, behavioral, biochemical, clinical, and pharmacological properties of GABA receptors. Emphasis is placed on exploring cutting-edge findings on the structureal properties of receptor sites, mechanisms of receptor expression, chemical agents that differentiate receptor subtypes, and phenotypes displayed by GABA receptor null mice. Chapters in this updated and expanded edition examine such topics as GABA receptor subypes, trafficking postsynaptic GABA receptors, GABA receptor mutations associated with idiopathic generalized epilepsies and febrile seizures, and GABA receptors as a potential therapeutic target.
Download or read book Versed written by Rae Armantrout and published by Wesleyan University Press. This book was released on 2010-08-01 with total page 143 pages. Available in PDF, EPUB and Kindle. Book excerpt: Winner of the 2010 Pulitzer Prize for Poetry Winner of the Pulitzer Prize for Poetry (2010) Winner of the National Book Critics Circle Award (2009) Rae Armantrout has always organized her collections of poetry as though they were works in themselves. Versed brings two of these sequences together, offering readers an expanded view of the arc of her writing. The poems in the first section, Versed, play with vice and versa, the perversity of human consciousness. They flirt with error and delusion, skating on a thin ice that inevitably cracks: "Metaphor forms / a crust / beneath which / the crevasse of each experience." Dark Matter, the second section, alludes to more than the unseen substance thought to make up the majority of mass in the universe. The invisible and unknowable are confronted directly as Armantrout's experience with cancer marks these poems with a new austerity, shot through with her signature wit and stark unsentimental thinking. Together, the poems of Versed part us from our assumptions about reality, revealing the gaps and fissures in our emotional and linguistic constructs, showing us ourselves where we are most exposed. A reader's companion is available at http://versedreader.site.wesleyan.edu/
Book Synopsis Clinical Methods by : Henry Kenneth Walker
Download or read book Clinical Methods written by Henry Kenneth Walker and published by Butterworth-Heinemann. This book was released on 1990 with total page 1128 pages. Available in PDF, EPUB and Kindle. Book excerpt: A guide to the techniques and analysis of clinical data. Each of the seventeen sections begins with a drawing and biographical sketch of a seminal contributor to the discipline. After an introduction and historical survey of clinical methods, the next fifteen sections are organized by body system. Each contains clinical data items from the history, physical examination, and laboratory investigations that are generally included in a comprehensive patient evaluation. Annotation copyrighted by Book News, Inc., Portland, OR
Book Synopsis The Clinical Toxicology Laboratory by : Leslie M. Shaw
Download or read book The Clinical Toxicology Laboratory written by Leslie M. Shaw and published by Amer. Assoc. for Clinical Chemistry. This book was released on 2001 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Drug and Alcohol Abuse by : M. A. Shuckit
Download or read book Drug and Alcohol Abuse written by M. A. Shuckit and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt: When this series was conceived, a book on substance abuse, including alcohol and alcoholism, was to be of highest priority. This priority was a reflection of my view that the subject is often taught inadequately or insufficiently in many training programs. Yet these problems are com monly encountered in clinical practice, and all too often in situations where accurate diagnosis and rapid treatment are of critical importance. We wanted a book that would be concise and easily readable but also comprehensive in its presentation of the basic principles underlying clinical manifestations, diagnosis, and management. It was of particular importance that the book also serve as an easy reference guide in emergency situations. Marc Schuckit, a man with impeccable credentials as a scholar and an experienced clinician in this field, has produced just such a book! Few psychiatrists, psychotherapists, or physicians will want to be without it. The presentation is comprehensive and in depth, yet so clear and well organized that it will also likely be of interest to medical students, nurses, and emergency personnel.
