Behavioral Genetics Of The Mouse Genetic Mouse Models Of Neurobehavioral Disorders

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Behavioral Genetics of the Mouse: Genetic mouse models of neurobehavioral disorders

Author : W. E. Crusio
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (21 download)

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Book Synopsis Behavioral Genetics of the Mouse: Genetic mouse models of neurobehavioral disorders by : W. E. Crusio

Download or read book Behavioral Genetics of the Mouse: Genetic mouse models of neurobehavioral disorders written by W. E. Crusio and published by . This book was released on 2013 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The first volume in the new Cambridge Handbooks in Behavioral Genetics, Behavioral Genetics of the Mouse provides baseline information on normal behaviors, essential in both the design of experiments using genetically-modified or pharmacologically-treated animals, and in the interpretation and analyses of the results obtained. Offering a comprehensive overview of the genetics of naturally-occurring variation in mouse behavior; from perception and spontaneous behaviors, such as exploration, aggression, social interactions and motor behaviors to reinforced behaviors such as the different types of learning. Also included are numerous examples of potential experimental problems, which will aid and guide researchers trying to troubleshoot their own studies. A lasting reference, the thorough and comprehensive reviews offer an easy entrance into the extensive literature in this field, and will prove invaluable to students and specialists alike"--

Behavioral Genetics of the Mouse: Volume 2, Genetic Mouse Models of Neurobehavioral Disorders

Author : Susanna Pietropaolo
Publisher : Cambridge University Press
ISBN 13 : 131606140X
Total Pages : 471 pages
Book Rating : 4.3/5 (16 download)

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Book Synopsis Behavioral Genetics of the Mouse: Volume 2, Genetic Mouse Models of Neurobehavioral Disorders by : Susanna Pietropaolo

Download or read book Behavioral Genetics of the Mouse: Volume 2, Genetic Mouse Models of Neurobehavioral Disorders written by Susanna Pietropaolo and published by Cambridge University Press. This book was released on 2014-09-25 with total page 471 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second volume of Behavioral Genetics of the Mouse provides a comprehensive overview of the major genetically modified mouse lines used to model human neurobehavioral disorders: from disorders of perception, of autonomous and motor functions to social and cognitive syndromes, drug abuse and dependence as well as neurodegenerative pathologies. Mouse models obtained with different types of genetic manipulations (i.e. transgenic, knockout/in mice) are described in their pathological phenotypes, with a special emphasis on behavioral abnormalities. The major results obtained with many of the existing models are discussed in depth highlighting their strengths and limitations. A lasting reference, the thorough reviews offer an easy entrance into the extensive literature in this field, and will prove invaluable to students and specialists alike.

Behavioral Genetics of the Mouse: Volume 1, Genetics of Behavioral Phenotypes

Author : Wim E. Crusio
Publisher : Cambridge University Press
ISBN 13 : 1107034817
Total Pages : 361 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis Behavioral Genetics of the Mouse: Volume 1, Genetics of Behavioral Phenotypes by : Wim E. Crusio

Download or read book Behavioral Genetics of the Mouse: Volume 1, Genetics of Behavioral Phenotypes written by Wim E. Crusio and published by Cambridge University Press. This book was released on 2013-04-25 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive review of the current state of our knowledge on the inheritance of normal behaviour in the laboratory mouse.

Neurobehavioral Genetics

Author : Byron C. Jones
Publisher : CRC Press
ISBN 13 : 9781420048384
Total Pages : 416 pages
Book Rating : 4.0/5 (483 download)

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Book Synopsis Neurobehavioral Genetics by : Byron C. Jones

Download or read book Neurobehavioral Genetics written by Byron C. Jones and published by CRC Press. This book was released on 2002-01-01 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurobehavioral Genetics: Methods and Applications covers classic and contemporary approaches to the study of the brain and behavior, including basic and clinical research. This book is designed as a reference for investigators wishing to incorporate genetic methods into neurobehavioral research. A broad spectrum of methods are integrated, unlike any other publication currently in print. Neurobehavioral Genetics: Methods and Applications presents different models, from invertebrates to genetically defined mammals. Introductory chapters demonstrate the scope and power of genetic methods that can be applied to neurobehavioral research from statistical methods and linkage analysis to contemporary molecular genetic approaches to search for candidate genes. The second half of the book covers the applications of quantitative and molecular genetics in basic and clinical research. Topics covered include animal behavior and neurobiology and human clinical problems including neurodegenerative diseases and psychiatric disorders.

Handbook of Neurobehavioral Genetics and Phenotyping

Author : Valter Tucci
Publisher : John Wiley & Sons
ISBN 13 : 1118540719
Total Pages : 648 pages
Book Rating : 4.1/5 (185 download)

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Book Synopsis Handbook of Neurobehavioral Genetics and Phenotyping by : Valter Tucci

Download or read book Handbook of Neurobehavioral Genetics and Phenotyping written by Valter Tucci and published by John Wiley & Sons. This book was released on 2017-03-06 with total page 648 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook of Behavioral Genetics and Phenotyping represents an integrative approach to neurobehavioural genetics; worldwide experts in their field will review all chapters. Advanced overviews of neurobehavioural characteristics will add immense value to the investigation of animal mutants and provide unique information about the genetics and behavioural understanding of animal models, under both normal and pathological conditions. Cross-species comparisons of neurobehavioural phenotypes will pave the way for an evolutionary understanding of behaviour. Moreover, while biological sciences are progressing towards a holistic approach to investigate the complexity of organisms (i.e., “systems biology” approach), an integrated analysis of behavioural phenotyping is still lacking. The Handbook of Behavioral Genetics and Phenotyping strengthens the cross-talk within disciplines that investigate the fundamental basis of behaviour and genetics. This will be the first volume in which traditionally distant fields including genomics, behaviour, electrophysiology, neuroeconomics, and computational neuroscience, among others, are evaluated together and simultaneously accounted for during discussions of future perspectives.

Genetically Defined Animal Models of Neurobehavioral Dysfunctions

Author : DRISCOLL
Publisher : Springer Science & Business Media
ISBN 13 : 148996732X
Total Pages : 323 pages
Book Rating : 4.4/5 (899 download)

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Book Synopsis Genetically Defined Animal Models of Neurobehavioral Dysfunctions by : DRISCOLL

Download or read book Genetically Defined Animal Models of Neurobehavioral Dysfunctions written by DRISCOLL and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 323 pages. Available in PDF, EPUB and Kindle. Book excerpt:

What's Wrong With My Mouse?

Author : Jacqueline N. Crawley
Publisher : John Wiley & Sons
ISBN 13 : 0470119047
Total Pages : 544 pages
Book Rating : 4.4/5 (71 download)

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Book Synopsis What's Wrong With My Mouse? by : Jacqueline N. Crawley

Download or read book What's Wrong With My Mouse? written by Jacqueline N. Crawley and published by John Wiley & Sons. This book was released on 2007-05-11 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr. Jacqueline N. Crawley, author of the First and Second Editions of What’s Wrong with My Mouse? Behavioral Phenotyping of Transgenic and Knockout Mice,continues to field calls and e-mails from molecular geneticists who ask: how do I run behavioral assays to find out what’s wrong with my mouse? Turn to What’s Wrong with My Mouse? to discover the wealth of mouse behavioral tasks and to get the guidance you need to select the best methods and necessary controls. Chapters are organized by behavioral domain, including measurements of general health, motor functions, sensory abilities, learning and memory, feeding and drinking, reproductive, social, emotional, and reward behaviors in mutant mice. Throughout the chapters, new behavioral tasks and new research discoveries have been added, bringing the Second Edition up to date with the latest science. In addition, the Second Edition includes two new chapters: "Neurodevelopment and Neurodegeneration" discusses mouse behavioral tasks relevant to neurodevelopmental diseases, such as mental retardation and autism, and to neurodegenerative diseases, such as Alzheimers, Parkinsons, Huntingtons, and amyotrophic lateral sclerosis. "Putting It All Together" recommends strategies for optimizing a battery of behavioral phenotyping tests to address your specific hypotheses about gene functions. The final chapter, "The Next Generation," examines new and emerging technologies. Throughout the book, the use of behavioral testing equipment is illustrated with photographs, diagrams, and representative data. Examples of behavioral tasks successfully applied to transgenic and knockout mouse models are provided, as well as references to the primary literature and step-by-step methods protocols. These features, along with a comprehensive index, listings of database and vendor websites, and an extensive list of references, make this book a valuable and practical resource for students and researchers.

Genetics and Genomics of Neurobehavioral Disorders

Author : Gene S. Fisch
Publisher : Springer Science & Business Media
ISBN 13 : 1592593534
Total Pages : 428 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Genetics and Genomics of Neurobehavioral Disorders by : Gene S. Fisch

Download or read book Genetics and Genomics of Neurobehavioral Disorders written by Gene S. Fisch and published by Springer Science & Business Media. This book was released on 2003-01-07 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: A clear and comprehensive account of how genetic abnormalities, neurobiology, and neuropsychology work together to manifest cognitive-behavioral dysfunction. The authors review the current status of research in autosomal disorders that produce cognitive-behavioral dysfunction and syndromal and nonsyndromal disorders that produce mental retardation.

Mouse Behavioral Testing

Author : Douglas Wahlsten
Publisher : Academic Press
ISBN 13 : 0123756758
Total Pages : 305 pages
Book Rating : 4.1/5 (237 download)

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Book Synopsis Mouse Behavioral Testing by : Douglas Wahlsten

Download or read book Mouse Behavioral Testing written by Douglas Wahlsten and published by Academic Press. This book was released on 2010-11-25 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mouse Behavioral Testing: How to Use Mice in Behavioral Neuroscience provides detailed explanations of how to conduct an experiment on mouse behavior from the initial planning of the research design through every step of the process until the data analysis phase. The book discusses the practical matters that need to be considered carefully when working with any species of animal, such as how many animals need to be tested. It describes the tests and techniques devised specifically for work with mice. Every step of the research process is illustrated with real situations encountered in previous studies. All examples are based on real experiments, and extensive details of several published experiments are provided. The essential features of a behavioral test protocol are outlined, and several complete protocols are provided. Methods to balance the order of tests and determine throughput are described, then a completely balanced order of tests in a complex experiment is presented. The book will be useful for those already familiar with the general principles of research but are new to the realm of behavioral testing of live mice. It will also serve as a text for a formal course, most likely at the graduate level. A guide to running a behavioral testing lab, including the many aspects of mouse research beyond the confines of the specific test Diagrams and photographs are shown for many kinds of apparatus and test situations with sufficient details such as dimensions to enable building of replicas Provides step-by-step instructions on planning and executing behavioral experiments in order to run them successfully

Behavioral Genetics

Author : Robert Plomin
Publisher : Macmillan
ISBN 13 : 1429205776
Total Pages : 552 pages
Book Rating : 4.4/5 (292 download)

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Book Synopsis Behavioral Genetics by : Robert Plomin

Download or read book Behavioral Genetics written by Robert Plomin and published by Macmillan. This book was released on 2008-02-22 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an overview of human and animal behavioral genetics and examines the crossroads where the fields of psychology, psychiatry, and genetics intersect.

Mouse Models of Neuroanatomical, Behavioral, and Genetic Correlates of Language-related Impairments

Author : Dongnhu Thuy Truong
Publisher :
ISBN 13 :
Total Pages : 410 pages
Book Rating : 4.:/5 (956 download)

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Book Synopsis Mouse Models of Neuroanatomical, Behavioral, and Genetic Correlates of Language-related Impairments by : Dongnhu Thuy Truong

Download or read book Mouse Models of Neuroanatomical, Behavioral, and Genetic Correlates of Language-related Impairments written by Dongnhu Thuy Truong and published by . This book was released on 2014 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Contributions to Behavior-genetic Analysis

Author : Gardner Lindzey
Publisher : Ardent Media
ISBN 13 : 9780390562753
Total Pages : 362 pages
Book Rating : 4.5/5 (627 download)

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Book Synopsis Contributions to Behavior-genetic Analysis by : Gardner Lindzey

Download or read book Contributions to Behavior-genetic Analysis written by Gardner Lindzey and published by Ardent Media. This book was released on 1970 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Mouse Models in the Study of Genetic Neurological Disorders

Author : Brian Popko
Publisher : Springer Science & Business Media
ISBN 13 : 146154887X
Total Pages : 370 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Mouse Models in the Study of Genetic Neurological Disorders by : Brian Popko

Download or read book Mouse Models in the Study of Genetic Neurological Disorders written by Brian Popko and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: The number of mouse models that are available for the study of human genetic neurological disorders is large and growing rapidly. Therefore, it was difficult to select the models that were reviewed in this volume. Clearly, there are important models that are not discussed, and perhaps a volume twice this size would have been more appropriate. Moreover, the pace at which new models are being developed and analyzed is rapid. As this volume goes to press, I am sure that additional mouse genes responsible for naturally occurring neurological disorders are being discovered and that many new transgenic and mutant mouse strains are being developed. Therefore, this volume should not be viewed as a comprehensive compendium, but rather as an update of work in progress. It is exhilarating to witness the fast pace at which these models are being established as important tools in the study of basic neuroscience and neurological disorders. It will be even more exciting to see their utilization in the development and testing of therapeutic interventions for these diseases. I would like to thank each of the authors who have contributed to this volume for their time and their expertise. I would also like to thank Drs. Timothy Coetzee and Joshua Corbin for their advice in the selection of the topics covered. I am deeply indebted to Dr. Kunihiko Suzuki, who first approached me with the idea for this volume, for his guidance throughout its preparation.

Transgenic and Knockout Models of Neuropsychiatric Disorders

Author : Gene S. Fisch
Publisher : Springer Science & Business Media
ISBN 13 : 1597450588
Total Pages : 295 pages
Book Rating : 4.5/5 (974 download)

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Book Synopsis Transgenic and Knockout Models of Neuropsychiatric Disorders by : Gene S. Fisch

Download or read book Transgenic and Knockout Models of Neuropsychiatric Disorders written by Gene S. Fisch and published by Springer Science & Business Media. This book was released on 2007-11-06 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this up-to-date survey and critical assessment of transgenic and knockout models in neuropsychiatry and behavior, a panel of leading researchers comprehensively assesses how and whether the genetic abnormalities produced from these models manifest the neuropsychiatric disorders to which they correspond. The authors focus on transgenic and knockout models of neurocognitive dysfunction and neuropsychiatric dysfunction. The discussion of neurobiological problems covers mental retardation, polyglutamate, and speech disorders, as well as disorders that involve cognitive, social, speech, and language dysfunction. The neuropsychiatric dysfunctions examined include psychosis and schizophrenia, anxiety, depression, and bipolar disorder.

Genetic Influences on Neural and Behavioral Functions

Author : Donald W. Pfaff
Publisher : CRC Press
ISBN 13 : 9781420048223
Total Pages : 510 pages
Book Rating : 4.0/5 (482 download)

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Book Synopsis Genetic Influences on Neural and Behavioral Functions by : Donald W. Pfaff

Download or read book Genetic Influences on Neural and Behavioral Functions written by Donald W. Pfaff and published by CRC Press. This book was released on 1999-07-27 with total page 510 pages. Available in PDF, EPUB and Kindle. Book excerpt: Utilizing the flood of information derived from the Human Genome Project and corresponding efforts to elucidate the mouse genome, Genetic Influences on Neural and Behavioral Functions provides a scholarly catalog, organized logically, of relations between the expression of specific genes, nerve cell biology and behavior, normal and abnormal, in animals AND humans. Sample topics include genes in relation to schiziphrenia, panic disorder, epilepsy, alcoholism, sleep, eating disorders, and more.

The Mouse In Animal Genetics And Breeding Research

Author : Eugene J Eisen
Publisher : World Scientific
ISBN 13 : 1783260262
Total Pages : 376 pages
Book Rating : 4.7/5 (832 download)

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Book Synopsis The Mouse In Animal Genetics And Breeding Research by : Eugene J Eisen

Download or read book The Mouse In Animal Genetics And Breeding Research written by Eugene J Eisen and published by World Scientific. This book was released on 2005-06-27 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: The sequencing of the mouse genome has placed the mouse front and center as the most important mammalian genetics model. However, no recent volume has detailed the genetic contributions the mouse has made across the spectrum of the life sciences; this book aims to fill that vacuum. Mouse genetics research has made enormous contributions to the understanding of basic genetics, human genetics, and livestock genetics and breeding. The wide-ranging topics in the book include the mouse genome sequencing effort, molecular dissection of quantitative traits, embryo biotechnology, ENU mutagenesis, and genetics of disease resistance, and have been written by experts in their respective fields.

Behavioral Neurogenetics

Author : John F. Cryan
Publisher : Springer Science & Business Media
ISBN 13 : 3642278590
Total Pages : 637 pages
Book Rating : 4.6/5 (422 download)

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Book Synopsis Behavioral Neurogenetics by : John F. Cryan

Download or read book Behavioral Neurogenetics written by John F. Cryan and published by Springer Science & Business Media. This book was released on 2012-05-04 with total page 637 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers a wide array of topics relevant to behavioral genetics from both a preclinical and clinical standpoint. Indeed in juxtaposing both areas of research the reader will appreciate the true translational nature of the field. Topics covered range from technical advances in genetic analysis in humans and animals to specific descriptions of advances in schizophrenia, attention disorders, depression and anxiety disorders, autism, aggression, neurodegeneration and neurodevelopmental disorders. The importance of gene-environment interactions is emphasised and the role of neuroimaging in unravelling the functional consequences of genetic variability described. This volume will be valued by both the basic scientist and clinician alike who may use it as a detailed reference book. It will also be of use to the novice to the field, to whom it will serve as an in-depth introduction to this exciting area of research.