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Bayesian Methods In Diagnostic Medicine
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Book Synopsis Bayesian Biostatistics and Diagnostic Medicine by : Lyle D. Broemeling
Download or read book Bayesian Biostatistics and Diagnostic Medicine written by Lyle D. Broemeling and published by CRC Press. This book was released on 2007-07-12 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are numerous advantages to using Bayesian methods in diagnostic medicine, which is why they are employed more and more today in clinical studies. Exploring Bayesian statistics at an introductory level, Bayesian Biostatistics and Diagnostic Medicine illustrates how to apply these methods to solve important problems in medicine and biology.
Book Synopsis Bayesian Methods in Diagnostic Medicine by : Lyle D. Broemeling
Download or read book Bayesian Methods in Diagnostic Medicine written by Lyle D. Broemeling and published by . This book was released on 2007 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Advanced Bayesian Methods for Medical Test Accuracy by : Lyle D. Broemeling
Download or read book Advanced Bayesian Methods for Medical Test Accuracy written by Lyle D. Broemeling and published by CRC Press. This book was released on 2016-04-19 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: Useful in many areas of medicine and biology, Bayesian methods are particularly attractive tools for the design of clinical trials and diagnostic tests, which are based on established information, usually from related previous studies. Advanced Bayesian Methods for Medical Test Accuracy begins with a review of the usual measures such as specificity
Book Synopsis Statistical Methods in Diagnostic Medicine by : Xiao-Hua Zhou
Download or read book Statistical Methods in Diagnostic Medicine written by Xiao-Hua Zhou and published by John Wiley & Sons. This book was released on 2014-08-21 with total page 597 pages. Available in PDF, EPUB and Kindle. Book excerpt: Praise for the First Edition " . . . the book is a valuable addition to the literature in the field, serving as a much-needed guide for both clinicians and advanced students."—Zentralblatt MATH A new edition of the cutting-edge guide to diagnostic tests in medical research In recent years, a considerable amount of research has focused on evolving methods for designing and analyzing diagnostic accuracy studies. Statistical Methods in Diagnostic Medicine, Second Edition continues to provide a comprehensive approach to the topic, guiding readers through the necessary practices for understanding these studies and generalizing the results to patient populations. Following a basic introduction to measuring test accuracy and study design, the authors successfully define various measures of diagnostic accuracy, describe strategies for designing diagnostic accuracy studies, and present key statistical methods for estimating and comparing test accuracy. Topics new to the Second Edition include: Methods for tests designed to detect and locate lesions Recommendations for covariate-adjustment Methods for estimating and comparing predictive values and sample size calculations Correcting techniques for verification and imperfect standard biases Sample size calculation for multiple reader studies when pilot data are available Updated meta-analysis methods, now incorporating random effects Three case studies thoroughly showcase some of the questions and statistical issues that arise in diagnostic medicine, with all associated data provided in detailed appendices. A related web site features Fortran, SAS®, and R software packages so that readers can conduct their own analyses. Statistical Methods in Diagnostic Medicine, Second Edition is an excellent supplement for biostatistics courses at the graduate level. It also serves as a valuable reference for clinicians and researchers working in the fields of medicine, epidemiology, and biostatistics.
Book Synopsis Bayesian Analysis of Time Series by : Lyle D. Broemeling
Download or read book Bayesian Analysis of Time Series written by Lyle D. Broemeling and published by CRC Press. This book was released on 2019-04-16 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: In many branches of science relevant observations are taken sequentially over time. Bayesian Analysis of Time Series discusses how to use models that explain the probabilistic characteristics of these time series and then utilizes the Bayesian approach to make inferences about their parameters. This is done by taking the prior information and via Bayes theorem implementing Bayesian inferences of estimation, testing hypotheses, and prediction. The methods are demonstrated using both R and WinBUGS. The R package is primarily used to generate observations from a given time series model, while the WinBUGS packages allows one to perform a posterior analysis that provides a way to determine the characteristic of the posterior distribution of the unknown parameters. Features Presents a comprehensive introduction to the Bayesian analysis of time series. Gives many examples over a wide variety of fields including biology, agriculture, business, economics, sociology, and astronomy. Contains numerous exercises at the end of each chapter many of which use R and WinBUGS. Can be used in graduate courses in statistics and biostatistics, but is also appropriate for researchers, practitioners and consulting statisticians. About the author Lyle D. Broemeling, Ph.D., is Director of Broemeling and Associates Inc., and is a consulting biostatistician. He has been involved with academic health science centers for about 20 years and has taught and been a consultant at the University of Texas Medical Branch in Galveston, The University of Texas MD Anderson Cancer Center and the University of Texas School of Public Health. His main interest is in developing Bayesian methods for use in medical and biological problems and in authoring textbooks in statistics. His previous books for Chapman & Hall/CRC include Bayesian Biostatistics and Diagnostic Medicine, and Bayesian Methods for Agreement.
Book Synopsis Assessment of Diagnostic Technology in Health Care by : Institute of Medicine
Download or read book Assessment of Diagnostic Technology in Health Care written by Institute of Medicine and published by National Academies Press. This book was released on 1989-02-01 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt: Technology assessment can lead to the rapid application of essential diagnostic technologies and prevent the wide diffusion of marginally useful methods. In both of these ways, it can increase quality of care and decrease the cost of health care. This comprehensive monograph carefully explores methods of and barriers to diagnostic technology assessment and describes both the rationale and the guidelines for meaningful evaluation. While proposing a multi-institutional approach, it emphasizes some of the problems involved and defines a mechanism for improving the evaluation and use of medical technology and essential resources needed to enhance patient care.
Book Synopsis Bayesian Analysis of Infectious Diseases by : Lyle D. Broemeling
Download or read book Bayesian Analysis of Infectious Diseases written by Lyle D. Broemeling and published by CRC Press. This book was released on 2021-02-08 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bayesian Analysis of Infectious Diseases -COVID-19 and Beyond shows how the Bayesian approach can be used to analyze the evolutionary behavior of infectious diseases, including the coronavirus pandemic. The book describes the foundation of Bayesian statistics while explicating the biology and evolutionary behavior of infectious diseases, including viral and bacterial manifestations of the contagion. The book discusses the application of Markov Chains to contagious diseases, previews data analysis models, the epidemic threshold theorem, and basic properties of the infection process. Also described are the chain binomial model for the evolution of epidemics. Features: Represents the first book on infectious disease from a Bayesian perspective. Employs WinBUGS and R to generate observations that follow the course of contagious maladies. Includes discussion of the coronavirus pandemic as well as many examples from the past, including the flu epidemic of 1918-1919. Compares standard non-Bayesian and Bayesian inferences. Offers a companion website with the R and WinBUGS code.
Download or read book Bayesian Methods written by Jeff Gill and published by CRC Press. This book was released on 2007-11-26 with total page 696 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first edition of Bayesian Methods: A Social and Behavioral Sciences Approach helped pave the way for Bayesian approaches to become more prominent in social science methodology. While the focus remains on practical modeling and basic theory as well as on intuitive explanations and derivations without skipping steps, this second edition incorporates the latest methodology and recent changes in software offerings. New to the Second Edition Two chapters on Markov chain Monte Carlo (MCMC) that cover ergodicity, convergence, mixing, simulated annealing, reversible jump MCMC, and coupling Expanded coverage of Bayesian linear and hierarchical models More technical and philosophical details on prior distributions A dedicated R package (BaM) with data and code for the examples as well as a set of functions for practical purposes such as calculating highest posterior density (HPD) intervals Requiring only a basic working knowledge of linear algebra and calculus, this text is one of the few to offer a graduate-level introduction to Bayesian statistics for social scientists. It first introduces Bayesian statistics and inference, before moving on to assess model quality and fit. Subsequent chapters examine hierarchical models within a Bayesian context and explore MCMC techniques and other numerical methods. Concentrating on practical computing issues, the author includes specific details for Bayesian model building and testing and uses the R and BUGS software for examples and exercises.
Book Synopsis Bayesian Survival Analysis by : Joseph G. Ibrahim
Download or read book Bayesian Survival Analysis written by Joseph G. Ibrahim and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 494 pages. Available in PDF, EPUB and Kindle. Book excerpt: Survival analysis arises in many fields of study including medicine, biology, engineering, public health, epidemiology, and economics. This book provides a comprehensive treatment of Bayesian survival analysis. It presents a balance between theory and applications, and for each class of models discussed, detailed examples and analyses from case studies are presented whenever possible. The applications are all from the health sciences, including cancer, AIDS, and the environment.
Book Synopsis Bayesian Methods in Epidemiology by : Lyle D. Broemeling
Download or read book Bayesian Methods in Epidemiology written by Lyle D. Broemeling and published by CRC Press. This book was released on 2013-08-13 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by a biostatistics expert with over 20 years of experience in the field, Bayesian Methods in Epidemiology presents statistical methods used in epidemiology from a Bayesian viewpoint. It employs the software package WinBUGS to carry out the analyses and offers the code in the text and for download online.The book examines study designs that
Book Synopsis Bayesian Inference for Stochastic Processes by : Lyle D. Broemeling
Download or read book Bayesian Inference for Stochastic Processes written by Lyle D. Broemeling and published by CRC Press. This book was released on 2017-12-12 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first book designed to introduce Bayesian inference procedures for stochastic processes. There are clear advantages to the Bayesian approach (including the optimal use of prior information). Initially, the book begins with a brief review of Bayesian inference and uses many examples relevant to the analysis of stochastic processes, including the four major types, namely those with discrete time and discrete state space and continuous time and continuous state space. The elements necessary to understanding stochastic processes are then introduced, followed by chapters devoted to the Bayesian analysis of such processes. It is important that a chapter devoted to the fundamental concepts in stochastic processes is included. Bayesian inference (estimation, testing hypotheses, and prediction) for discrete time Markov chains, for Markov jump processes, for normal processes (e.g. Brownian motion and the Ornstein–Uhlenbeck process), for traditional time series, and, lastly, for point and spatial processes are described in detail. Heavy emphasis is placed on many examples taken from biology and other scientific disciplines. In order analyses of stochastic processes, it will use R and WinBUGS. Features: Uses the Bayesian approach to make statistical Inferences about stochastic processes The R package is used to simulate realizations from different types of processes Based on realizations from stochastic processes, the WinBUGS package will provide the Bayesian analysis (estimation, testing hypotheses, and prediction) for the unknown parameters of stochastic processes To illustrate the Bayesian inference, many examples taken from biology, economics, and astronomy will reinforce the basic concepts of the subject A practical approach is implemented by considering realistic examples of interest to the scientific community WinBUGS and R code are provided in the text, allowing the reader to easily verify the results of the inferential procedures found in the many examples of the book Readers with a good background in two areas, probability theory and statistical inference, should be able to master the essential ideas of this book.
Book Synopsis Bayesian Approaches to Clinical Trials and Health-Care Evaluation by : David J. Spiegelhalter
Download or read book Bayesian Approaches to Clinical Trials and Health-Care Evaluation written by David J. Spiegelhalter and published by John Wiley & Sons. This book was released on 2004-05-05 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: READ ALL ABOUT IT! David Spiegelhalter has recently joined the ranks of Isaac Newton, Charles Darwin and Stephen Hawking by becoming a fellow of the Royal Society. Originating from the Medical Research Council’s biostatistics unit, David has played a leading role in the Bristol heart surgery and Harold Shipman inquiries. Order a copy of this author’s comprehensive text TODAY! The Bayesian approach involves synthesising data and judgement in order to reach conclusions about unknown quantities and make predictions. Bayesian methods have become increasingly popular in recent years, notably in medical research, and although there are a number of books on Bayesian analysis, few cover clinical trials and biostatistical applications in any detail. Bayesian Approaches to Clinical Trials and Health-Care Evaluation provides a valuable overview of this rapidly evolving field, including basic Bayesian ideas, prior distributions, clinical trials, observational studies, evidence synthesis and cost-effectiveness analysis. Covers a broad array of essential topics, building from the basics to more advanced techniques. Illustrated throughout by detailed case studies and worked examples Includes exercises in all chapters Accessible to anyone with a basic knowledge of statistics Authors are at the forefront of research into Bayesian methods in medical research Accompanied by a Web site featuring data sets and worked examples using Excel and WinBUGS - the most widely used Bayesian modelling package Bayesian Approaches to Clinical Trials and Health-Care Evaluation is suitable for students and researchers in medical statistics, statisticians in the pharmaceutical industry, and anyone involved in conducting clinical trials and assessment of health-care technology.
Book Synopsis Bayesian Thinking in Biostatistics by : Gary L Rosner
Download or read book Bayesian Thinking in Biostatistics written by Gary L Rosner and published by CRC Press. This book was released on 2021-03-15 with total page 622 pages. Available in PDF, EPUB and Kindle. Book excerpt: Praise for Bayesian Thinking in Biostatistics: "This thoroughly modern Bayesian book ...is a 'must have' as a textbook or a reference volume. Rosner, Laud and Johnson make the case for Bayesian approaches by melding clear exposition on methodology with serious attention to a broad array of illuminating applications. These are activated by excellent coverage of computing methods and provision of code. Their content on model assessment, robustness, data-analytic approaches and predictive assessments...are essential to valid practice. The numerous exercises and professional advice make the book ideal as a text for an intermediate-level course..." -Thomas Louis, Johns Hopkins University "The book introduces all the important topics that one would usually cover in a beginning graduate level class on Bayesian biostatistics. The careful introduction of the Bayesian viewpoint and the mechanics of implementing Bayesian inference in the early chapters makes it a complete self- contained introduction to Bayesian inference for biomedical problems....Another great feature for using this book as a textbook is the inclusion of extensive problem sets, going well beyond construed and simple problems. Many exercises consider real data and studies, providing very useful examples in addition to serving as problems." - Peter Mueller, University of Texas With a focus on incorporating sensible prior distributions and discussions on many recent developments in Bayesian methodologies, Bayesian Thinking in Biostatistics considers statistical issues in biomedical research. The book emphasizes greater collaboration between biostatisticians and biomedical researchers. The text includes an overview of Bayesian statistics, a discussion of many of the methods biostatisticians frequently use, such as rates and proportions, regression models, clinical trial design, and methods for evaluating diagnostic tests. Key Features Applies a Bayesian perspective to applications in biomedical science Highlights advances in clinical trial design Goes beyond standard statistical models in the book by introducing Bayesian nonparametric methods and illustrating their uses in data analysis Emphasizes estimation of biomedically relevant quantities and assessment of the uncertainty in this estimation Provides programs in the BUGS language, with variants for JAGS and Stan, that one can use or adapt for one's own research The intended audience includes graduate students in biostatistics, epidemiology, and biomedical researchers, in general Authors Gary L. Rosner is the Eli Kennerly Marshall, Jr., Professor of Oncology at the Johns Hopkins School of Medicine and Professor of Biostatistics at the Johns Hopkins Bloomberg School of Public Health. Purushottam (Prakash) W. Laud is Professor in the Division of Biostatistics, and Director of the Biostatistics Shared Resource for the Cancer Center, at the Medical College of Wisconsin. Wesley O. Johnson is professor Emeritus in the Department of Statistics as the University of California, Irvine.
Book Synopsis Bayesian Methods for Measures of Agreement by : Lyle D. Broemeling
Download or read book Bayesian Methods for Measures of Agreement written by Lyle D. Broemeling and published by CRC Press. This book was released on 2009-01-12 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using WinBUGS to implement Bayesian inferences of estimation and testing hypotheses, Bayesian Methods for Measures of Agreement presents useful methods for the design and analysis of agreement studies. It focuses on agreement among the various players in the diagnostic process.The author employs a Bayesian approach to provide statistical inferences
Book Synopsis Bayesian Biostatistics by : Donald A. Berry
Download or read book Bayesian Biostatistics written by Donald A. Berry and published by CRC Press. This book was released on 2018-10-03 with total page 702 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work provides descriptions, explanations and examples of the Bayesian approach to statistics, demonstrating the utility of Bayesian methods for analyzing real-world problems in the health sciences. The work considers the individual components of Bayesian analysis.;College or university bookstores may order five or more copies at a special student price, available on request from Marcel Dekker, Inc.
Book Synopsis Bayesian Methods in Structural Bioinformatics by : Thomas Hamelryck
Download or read book Bayesian Methods in Structural Bioinformatics written by Thomas Hamelryck and published by Springer. This book was released on 2012-03-23 with total page 399 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is an edited volume, the goal of which is to provide an overview of the current state-of-the-art in statistical methods applied to problems in structural bioinformatics (and in particular protein structure prediction, simulation, experimental structure determination and analysis). It focuses on statistical methods that have a clear interpretation in the framework of statistical physics, rather than ad hoc, black box methods based on neural networks or support vector machines. In addition, the emphasis is on methods that deal with biomolecular structure in atomic detail. The book is highly accessible, and only assumes background knowledge on protein structure, with a minimum of mathematical knowledge. Therefore, the book includes introductory chapters that contain a solid introduction to key topics such as Bayesian statistics and concepts in machine learning and statistical physics.
Book Synopsis Bayesian Methods in Pharmaceutical Research by : Emmanuel Lesaffre
Download or read book Bayesian Methods in Pharmaceutical Research written by Emmanuel Lesaffre and published by CRC Press. This book was released on 2020-04-15 with total page 547 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the early 2000s, there has been increasing interest within the pharmaceutical industry in the application of Bayesian methods at various stages of the research, development, manufacturing, and health economic evaluation of new health care interventions. In 2010, the first Applied Bayesian Biostatistics conference was held, with the primary objective to stimulate the practical implementation of Bayesian statistics, and to promote the added-value for accelerating the discovery and the delivery of new cures to patients. This book is a synthesis of the conferences and debates, providing an overview of Bayesian methods applied to nearly all stages of research and development, from early discovery to portfolio management. It highlights the value associated with sharing a vision with the regulatory authorities, academia, and pharmaceutical industry, with a view to setting up a common strategy for the appropriate use of Bayesian statistics for the benefit of patients. The book covers: Theory, methods, applications, and computing Bayesian biostatistics for clinical innovative designs Adding value with Real World Evidence Opportunities for rare, orphan diseases, and pediatric development Applied Bayesian biostatistics in manufacturing Decision making and Portfolio management Regulatory perspective and public health policies Statisticians and data scientists involved in the research, development, and approval of new cures will be inspired by the possible applications of Bayesian methods covered in the book. The methods, applications, and computational guidance will enable the reader to apply Bayesian methods in their own pharmaceutical research.
