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Author : Thomas Anthony Hess
Publisher :
ISBN 13 :
Total Pages : 112 pages
Book Rating : 4.:/5 (639 download)
Download or read book Autoregulation of Renal Blood Flow in the Nonfiltering Kidney written by Thomas Anthony Hess and published by . This book was released on 1979 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Lerner B. Hinshaw
Publisher :
ISBN 13 :
Total Pages : 24 pages
Book Rating : 4.3/5 ( download)
Download or read book Mechanism of Autoregulation in the Intact Kidney written by Lerner B. Hinshaw and published by . This book was released on 1963 with total page 24 pages. Available in PDF, EPUB and Kindle. Book excerpt: The subject of the investigation is the mechanism of autoregulation of blood flow in the intact kidney. The left kidney of the anesthetized dog was exposed via a flank approach. Renal venous outflow was measured during control periods and following separate elevations of renal artery pressure, renal vein pressure, and ureteral pressure. Extravascular pressure (tissue pressure) was estimated by obtaining values of (a) deep vein pressure; (b) needle pressure; (c) and (d) large vein pressure and ureteral pressure elevations resulting in significant decreases in renal blood flow. Results are in agreement with previously reported studies regarding the important role of extravascular pressure in autoregulation. Increases in renal artery pressure result in elevations of extravascular pressure which compress the renal vasculature. Increases in renal vein and ureteral pressures did not decrease renal blood flow until approximating or exceeding resting tissue pressure. Results from carotid artery occlusion experiments indicate that extrarenal humoral influences may be superimposed on the autoregulatory phenomenon. (Author).
Author : Arnold Henry Blatt
Publisher :
ISBN 13 :
Total Pages : 126 pages
Book Rating : 4.:/5 (228 download)
Download or read book Studies on Autoregulation of Renal Blood Flow written by Arnold Henry Blatt and published by . This book was released on 1966 with total page 126 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Clyde Rayburn Replogle
Publisher :
ISBN 13 :
Total Pages : 234 pages
Book Rating : 4.3/5 (129 download)
Download or read book A Proposed Model for Renal Blood Flow Control written by Clyde Rayburn Replogle and published by . This book was released on 1967 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Christopher J. Lote
Publisher :
ISBN 13 :
Total Pages : 360 pages
Book Rating : 4.3/5 (91 download)
Download or read book Advances in Renal Physiology written by Christopher J. Lote and published by . This book was released on 1986 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Nicholas Graygory Andreas Mitrou
Publisher :
ISBN 13 :
Total Pages : 120 pages
Book Rating : 4.:/5 (112 download)
Download or read book Internephron Synchronization of Renal Blood Flow Autoregulation written by Nicholas Graygory Andreas Mitrou and published by . This book was released on 2015 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt: Renal autoregulation is the system that maintains a constant renal blood flow when arterial pressure fluctuates. Failure of autoregulation leads to renal damage and subsequent failure. There are two mechanisms of autoregulation. First is the myogenic response, which is common to almost all microvascular beds. Second is tubuloglomerular feedback, which is a slower system that fine-tunes the delivery of solutes to each nephorn. Autoregulation is well studied. However, limitations in measurement techniques, and simplifying assumption, previously forced us to assume that all nephrons in the kidney act independently in response to local changes in blood pressure. The goal of this dissertation was to determine the presence, extent, and mechanism of network behaviour in renal autoregulation. In this dissertation I show that the mechanisms of renal autoregulation are synchronized over macroscopic regions of the renal surface, and that the spatial distribution of synchronization can be modulated by nitric oxide. Then I show that the patterns of synchronization of autoregulation on the surface of the kidney are governed by the underlying arterial anatomy. We show that the mechanism of internephron synchronization is chiefly dependent on gap junctional intercellular communication, and that removal of this communication pathway reduces the efficiency of autoregulation overall. Finally, impaired autoregulation in early diabetes is shown to coincide with a reduction in spatial smoothing of autoregulation. By the end, I have shown that internephron synchronization is present in the kidney, and 1) synchronization is modulated by an important hormonal modulator, nitric oxide, 2) that arterial anatomy determines divisions between synchronized clusters, 3) gap junctions mediate synchronization and contribute to autoregulation effectiveness, and 4) that network behaviour of autoregulation is reduced in early diabetes, linked with impaired autoregulation. Overall, this shows that internephron synchronization is an important aspect of renal autoregulation, and it must be considered in the future when studying this field.
Author : Civil Aeromedical Research Institute (U.S.)
Publisher :
ISBN 13 :
Total Pages : 12 pages
Book Rating : 4.:/5 (324 download)
Download or read book Mechanism of Autoregulation in the Intact Kidney written by Civil Aeromedical Research Institute (U.S.) and published by . This book was released on 1964 with total page 12 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Christopher Scully
Publisher :
ISBN 13 :
Total Pages : 334 pages
Book Rating : 4.:/5 (89 download)
Download or read book Detection of Spatial and Temporal Interactions in Renal Autoregulation Dynamics written by Christopher Scully and published by . This book was released on 2013 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: Abstract: Renal autoregulation stabilizes renal blood flow to protect the glomerular capillaries and maintain glomerular filtration rates through two mechanisms: tubuloglomerular feedback (TGF) and the myogenic response (MR). It is considered that the feedback mechanisms operate independently in each nephron (the functional unit of the kidney) within a kidney, but renal autoregulation dynamics can be coupled between vascular connected nephrons. It has also been shown that the mechanisms are time-varying and interact with each other. Understanding of the significance of such complex behavior has been limited by absence of techniques capable of monitoring renal flow signals among more than 2 or 3 nephrons simultaneously. The purpose of this thesis was to develop approaches to allow the identification and characterization of spatial and temporal properties of renal autoregulation dynamics. We present evidence that laser speckle perfusion imaging (LSPI) effectively captures renal autoregulation dynamics in perfusion signals across the renal cortex of anaesthetized rats and that spatial heterogeneity of the dynamics is present and can be investigated using LSPI. Next, we present a novel approach to segment LSPI of the renal surface into phase synchronized clusters representing areas with coupled renal autoregulation dynamics. Results are shown for the MR and demonstrate that when a signal is present phase synchronized regions can be identified. We then describe an approach to identify quadratic phase coupling between the TGF and MR mechanisms in time and space. Using this approach we can identify locations across the renal surface where both mechanisms are operating cooperatively. Finally, we show how synchronization between nephrons can be investigated in relation to renal autoregulation effectiveness by comparing phase synchronization estimates from LSPI with renal autoregulation system properties estimated from renal blood flow and blood pressure measurements. Overall, we have developed approaches to 1) capture renal autoregulation dynamics across the renal surface, 2) identify regions with phase synchronized renal autoregulation dynamics, 3) quantify the presence of the TGF-MR interaction across the renal surface, and 4) determine how the above vary over time. The described tools allow for investigations of the significance and mechanisms behind the complex spatial interactions and time-varying properties of renal autoregulation dynamics.
Author : William J. Arendshorst
Publisher :
ISBN 13 :
Total Pages : 7 pages
Book Rating : 4.:/5 (452 download)
Download or read book Autoregulation of Blood Flow in the Rat Kidney written by William J. Arendshorst and published by . This book was released on 1975* with total page 7 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Society for Experimental Biology and Medicine (New York, N.Y.)
Publisher :
ISBN 13 :
Total Pages : 612 pages
Book Rating : 4.3/5 (97 download)
Download or read book Proceedings of the Society for Experimental Biology and Medicine written by Society for Experimental Biology and Medicine (New York, N.Y.) and published by . This book was released on 1985 with total page 612 pages. Available in PDF, EPUB and Kindle. Book excerpt: List of members in each volume.
Author :
Publisher :
ISBN 13 :
Total Pages : 812 pages
Book Rating : 4.M/5 ( download)
Download or read book Kidney Disease and Nephrology Index written by and published by . This book was released on 1977-07 with total page 812 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Karl Skorecki
Publisher : Elsevier Health Sciences
ISBN 13 : 0323550851
Total Pages : 2748 pages
Book Rating : 4.3/5 (235 download)
Download or read book Brenner and Rector's The Kidney E-Book written by Karl Skorecki and published by Elsevier Health Sciences. This book was released on 2019-09-25 with total page 2748 pages. Available in PDF, EPUB and Kindle. Book excerpt: Put the world’s most well-known kidney reference to work in your practice with the 11th Edition of Brenner & Rector’s The Kidney. This two-volume masterwork provides expert, well-illustrated information on everything from basic science and pathophysiology to clinical best practices. Addressing current issues such as new therapies for cardiorenal syndrome, the increased importance of supportive or palliative care in advanced chronic kidney disease, increasing live kidney donation in transplants, and emerging discoveries in stem cell and kidney regeneration, this revised edition prepares you for any clinical challenge you may encounter. Extensively updated chapters throughout, providing the latest scientific and clinical information from authorities in their respective fields. Lifespan coverage of kidney health and disease from pre-conception through fetal and infant health, childhood, adulthood, and old age. Discussions of today’s hot topics, including the global increase in acute kidney injury, chronic kidney disease of unknown etiology, cardiovascular disease and renal disease, and global initiatives for alternatives in areas with limited facilities for dialysis or transplant. New Key Points that represent either new findings or "pearls" of information that are not widely known or understood. New Clinical Relevance boxes that highlight the information you must know during a patient visit, such as pertinent physiology or pathophysiology. Hundreds of full-color, high-quality photographs as well as carefully chosen figures, algorithms, and tables that illustrate essential concepts, nuances of clinical presentation and technique, and clinical decision making. A new editor who is a world-renowned expert in global health and nephrology care in underserved populations, Dr. Valerie A. Luyckx from University of Zürich. Board review-style questions to help you prepare for certification or recertification.
Author : Saulo Klahr
Publisher : Springer Science & Business Media
ISBN 13 : 146156722X
Total Pages : 1044 pages
Book Rating : 4.4/5 (615 download)
Download or read book Contemporary Nephrology written by Saulo Klahr and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 1044 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is the first of a biannual series entitled Contemporary Nephrology. The series intends to provide the reader with a broad, authoritative review of the important developments that have occurred during the previous two years in the major areas of both basic and clinical nephrology. We have been fortunate to enlist a distinguished group of scientists, teachers, and clinicians to serve as members of the Editorial Board of this series. We are grateful to them for the outstand ing contributions they have made to this first volume of Contemporary Nephrology. This volume has fifteen chapters. The first four chapters deal with more basic aspects of nephrology: Membrane Transport (Schafer); Renal Physiology (Knox and Spielman); Renal Metabolism (School werth); and Renal Prostaglandins (Dunn). Chapters 5-10 are more pathophysiologically oriented, and each contains an "appropriate mix" of basic and clinical information. This group of chapters includes Acid-Base Physiology and Pathophysiology (Arruda and Kurtzman); Mineral Metabolism in Health and Disease (Agus, Goldfarb, and Was serstein); Hypertension and the Renin-Angiotensin-Aldosterone Axis (Williams and Hollenberg); Immunologically Mediated Renal Disease (Glassock); Acute Renal Failure and Toxic Nephropathy (Anderson and Gross); and the Kidney in Systemic Disease (Martinez-Maldonado). The last five chapters, which are more clinically oriented, include Uremia (Friedman and Lundin); Nutrition in Renal Disease (Mitch); Dialysis (Maher); Renal Transplantation (Strom); and, finally, Drugs and the Kidney (Bennett).
Author : L. Takács
Publisher : Elsevier
ISBN 13 : 1483153800
Total Pages : 689 pages
Book Rating : 4.4/5 (831 download)
Download or read book Kidney and Body Fluids written by L. Takács and published by Elsevier. This book was released on 2013-10-22 with total page 689 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Physiological Sciences, Volume 11: Kidney and Body Fluids offers a thorough discussion of the experiments, research, and investigations done on the function, composition, and chemical reactions the kidney and body fluids undergo. Divided into 10 parts and having 88 chapters, the book features lengthy literature of authors who have actively pursued research on kidney and body fluids. Areas covered include renal cell cultures and blood flow; glomerulotubular balance; cell ionic activity and element analysis; electrophysiology and epithelial transport; and tubular handling of phosphate and calcium. Tubular acidification, regulation of water balance, and extracellular volume control are also discussed. The text presents as well how the study of the kidney and body fluids have captured the interest of physiologists and other individuals interested in this discipline. The book is a dependable source of information for those interested in the composition, function, and chemical reactions of the kidney and body fluids. The text is highly recommended to scholars and students who find this field of study interesting.
Author : Esmail Koushanpour
Publisher : Springer Science & Business Media
ISBN 13 : 1475719124
Total Pages : 402 pages
Book Rating : 4.4/5 (757 download)
Download or read book Renal Physiology written by Esmail Koushanpour and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first edition of this book was well received by updated. The two of us have made further collab orative efforts to present a better understanding of medical students, graduate students, and clinicians interested in furthering their understanding of basic the function of the kidney in conjunction with the principles of renal physiology. Most of the reviews most recent anatomical findings. of the first edition and comments from the various The second edition consists of 13 Chapters and 3 instructors who used the book were very positive Appendices. As in the first edition, the anatomical and complimentary with regard to the presentation description of the kidney is incorporated into the of the physiological information and the use of the various chapters dealing with kidney functions. Most system analysis approach to describe renal function. of the anatomical information was written by Wil These positive and encouraging comments over the helm Kriz. The physiological information was writ past nine years, since the publication of the first ten by Esmail Koushanpour, except for Chapter 12 edition, gave us the impetus to consider the prepa which was jointly written. Chapters 1 through 3 were ration of a second edition.
Author : Robert J. Alpern
Publisher : Elsevier
ISBN 13 : 0080559506
Total Pages : 2922 pages
Book Rating : 4.0/5 (85 download)
Download or read book Seldin and Giebisch's The Kidney written by Robert J. Alpern and published by Elsevier. This book was released on 2007-10-10 with total page 2922 pages. Available in PDF, EPUB and Kindle. Book excerpt: A classic nephrology reference for over 20 years, Seldin & Giebisch's The Kidney, is the acknowledged authority on renal physiology and pathophysiology. The fourth edition follows the changed focus of nephrology research to the study of how individual molecules work together to affect cellular and organ function, emphasizing the mechanisms of disease. With over 40 new chapters and over 1000 illustrations, this edition offers the most in-depth discussion anywhere of the physiologic and pathophysiologic processes of renal disease. Comprehensive, authoritative coverage progresses from molecular biology and cell physiology to clinical issues regarding renal function and dysfunction. If you research the development of normal renal function or the mechanisms underlying renal disease, Seldin & Giebisch's The Kidney is your number one source for information.* Offers the most comprehensive coverage of fluid and electrolyte regulation and dysregulation in 51 completely revised chapters unlike Brenner & Rector's The Kidney which devotes only 7 chapters to this topic.* Includes 3 sections, 31 chapters, devoted to regulation and disorders of acid-base homeostasis, and epithelial and nonepithelial transport regulation. Brenner & Rector's only devotes 5 chapters to these topics.* Previous three editions edited by Donald Seldin and Gerhard Giebisch, world renowned names in nephrology. The title for the fourth edition has been changed to reflect their considerable work on previous editions and they have also written the forward for this edition. * Over 20 million adults over age 20 have chronic kidney disease with the number of people diagnosed doubling each decade making it America's ninth leading cause of death.
Author : National Heart, Lung, and Blood Institute. Hypertension Task Force
Publisher :
ISBN 13 :
Total Pages : 192 pages
Book Rating : 4.3/5 (121 download)
Download or read book Report of the Hypertension Task Force written by National Heart, Lung, and Blood Institute. Hypertension Task Force and published by . This book was released on 1979 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt:
