Read Books Online and Download eBooks, EPub, PDF, Mobi, Kindle, Text Full Free.
Download Autophagy In Autoimmunity full books in PDF, epub, and Kindle. Read online Autophagy In Autoimmunity ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Author : Xu-jie Zhou
Publisher : Frontiers Media SA
ISBN 13 : 2889458121
Total Pages : 161 pages
Book Rating : 4.8/5 (894 download)
Download or read book Autophagy in Autoimmunity written by Xu-jie Zhou and published by Frontiers Media SA. This book was released on 2019-05-15 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Carlo Perricone
Publisher : Academic Press
ISBN 13 : 012814307X
Total Pages : 728 pages
Book Rating : 4.1/5 (281 download)
Download or read book Mosaic of Autoimmunity written by Carlo Perricone and published by Academic Press. This book was released on 2019-02-15 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Mosaic of Autoimmunity: The Novel Factors of Autoimmune Diseases describes the multifactorial origin and diversity of expression of autoimmune diseases in humans. The term implies that different combinations of factors in autoimmunity produce varying and unique clinical pictures in a wide spectrum of autoimmune diseases. Most of the factors involved in autoimmunity can be categorized into four groups: genetic, immune defects, hormonal and environmental factors. In this book, the environmental factors are reviewed, including infectious agents, vaccines as triggers of autoimmunity, smoking and its relationship with rheumatoid arthritis, systemic lupus erythematosus, thyroid disease, multiple sclerosis and inflammatory bowel diseases. An entirely new syndrome, the autoimmune/inflammatory syndrome induced by adjuvants (ASIA), is also included, along with other diseases that are now recognized as having an autoimmune etiopathogenesis. Highlights the concept of the mosaic of autoimmune manifestations Includes new visions on unsuspected molecules Provides updated knowledge to physicians helping patients with autoimmune diseases Presents thorough, up-to-date information on specific diseases, along with clinical applications
![Download Autophagy and NF-[kappa]B Activation in Autoimmunity PDF Online Free](https://books.google.com/books/content/images/frontcover/HzLhswEACAAJ?fife=w200-h370)
Author : Dennis Jau-Tyng Wu
Publisher :
ISBN 13 : 9781369795493
Total Pages : pages
Book Rating : 4.7/5 (954 download)
Download or read book Autophagy and NF-[kappa]B Activation in Autoimmunity written by Dennis Jau-Tyng Wu and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Recently, autophagy-related genes polymorphisms have been implicated in several autoimmune diseases including systemic lupus erythematosus, rheumatoid arthritis, psoriasis, and multiple sclerosis. Autophagy is the highly conserved protein degradation pathway from yeasts to humans and is essential for removing protein aggregates, misfold proteins in healthy cells. More and more studies reveal autophagy and autophagy-related proteins also participate in immune regulation, such as removal of intracellular bacteria, inflammatory cytokine secretion, antigen presentation, and lymphocyte development. The generation of autophagy-related protein knockout mice advances our understanding of autophagy in the immune system and autoimmunity tremendously. For instance, autophagy-related proteins deficient mice are protected from experimental autoimmune encephalomyelitis, an animal model of multiple sclerosis, and autophagy-related proteins deficient mice are protected from TNF[alpha] joint destruction in experimental arthritis. One of the links between autophagy and autoimmune diseases is activation of nuclear factor [kappa]B (NF-[kappa]B). Autophagy has been shown to regulate NF-[kappa]B activation while NF-[kappa]B activation often leads to autoimmune disease pathogenesis. In this article, we explore the role of a novel autophagy-related protein WDFY3 in NF-[kappa]B activation and an animal model of autoimmune diseases. More detailed understanding the role of autophagy and autophagy-related proteins is needed for developing therapeutic interventions target autophagy pathway/autophagy proteins for autoimmune diseases.
Author : Maria Chiara Maiuri
Publisher : Springer
ISBN 13 : 3319300792
Total Pages : 409 pages
Book Rating : 4.3/5 (193 download)
Download or read book Autophagy Networks in Inflammation written by Maria Chiara Maiuri and published by Springer. This book was released on 2016-08-17 with total page 409 pages. Available in PDF, EPUB and Kindle. Book excerpt: Autophagy principally serves an adaptive function to protect organisms against diverse human pathologies, including cancer and neurodegeneration. Recent developments using in vitro, ex vivo and in vivo models show the involvement of the autophagy pathway in immunity and inflammation. Moreover, direct interactions between autophagy proteins and immune signalling molecules have also been demonstrated. Defects in autophagy - similar to cancer, neurodegenerative diseases and aging - through autophagy gene mutation and/or microbial antagonism, may underlie the pathogenesis of many infectious diseases and inflammatory syndromes. In spite of the increasing awareness of the importance of autophagy in these pathophysiological conditions, this process remains underestimated and is often overlooked. As a consequence, its role in the initiation, stability, maintenance, and progression of these diseases are still poorly understood. This book reviews the recent advances regarding the functions of the autophagy pathway and autophagy proteins in immunity and inflammation, focusing on their role in self-nonself distinction, their implications in innate and adaptive immune responses and their dysregulation in the pathology of certain inflammatory and autoimmune diseases.
Author : Weidong Le
Publisher : Springer Nature
ISBN 13 : 9811542724
Total Pages : 734 pages
Book Rating : 4.8/5 (115 download)
Download or read book Autophagy: Biology and Diseases written by Weidong Le and published by Springer Nature. This book was released on 2020-07-15 with total page 734 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book consists of 3 volumes: Basic Science (Volume 1), Clinical Science (Volume 2) and Technology and Methodology (Volume 3). Volume 2 focuses on the clinical aspects of autophagy research, discussing the role of autophagy in neuropsychiatric disorders, the cardiovascular, immune, digestive and endocrine systems, as well as tumors, infection, the kidney, and the respiratory and hematological systems. It also addresses autophagy-related drug development. Written and edited by a team of 90 experts, and presenting the state of the art in autophagy research, this book is a valuable reference resource for researchers and clinicians alike. It can also be used as supplementary material for graduate students majoring in biology and medicine
Author : Vojo Deretic
Publisher : John Wiley & Sons
ISBN 13 : 3527608540
Total Pages : 286 pages
Book Rating : 4.5/5 (276 download)
Download or read book Autophagy in Immunity and Infection written by Vojo Deretic and published by John Wiley & Sons. This book was released on 2006-08-21 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: This first book to cover this new topic at the interface of cell biology, immunology and infection biology offers a unique insight as to how the innate and possibly the adaptive immune system are shaped by cellular mechanisms. Following a comprehensive introduction to autophagy, the work features cellular mechanisms and medical implications, structured according to all major pathogens, while also covering emerging infectious diseases, such as tuberculosis. Edited by one of the authors of a groundbreaking paper on this topic.
Author : M. A. Hayat
Publisher : Elsevier
ISBN 13 : 0124115144
Total Pages : 435 pages
Book Rating : 4.1/5 (241 download)
Download or read book Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging written by M. A. Hayat and published by Elsevier. This book was released on 2013-09-03 with total page 435 pages. Available in PDF, EPUB and Kindle. Book excerpt: Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging is a complete, authoritative examination of the role of autophagy in health and disease. Understanding this phenomenon is vital for the studies of cancer, aging, neurodegeneration, immunology, and infectious diseases. Comprehensive and forward thinking, this four-volume work offers a valuable guide to cellular processes while encouraging researchers to explore their potentially important connections. Understanding the role of autophagy is critical, considering its association with numerous biological processes, including cellular development and differentiation, cancer (both antitumor and protumor functions), immunity, infectious diseases, inflammation, maintenance of homeostasis, response to cellular stress, and degenerative diseases such as Alzheimer's, Parkinson's, Huntington's, amyotrophic lateral sclerosis, and prion diseases. Cell homeostasis is achieved by balancing biosynthesis and cellular turnover. In spite of the increasing importance of autophagy in various pathophysiological conditions mentioned above, this process remains underestimated and overlooked. As a consequence, its role in the initiation, stability, maintenance, and progression of these and other diseases (e.g., autoimmune disease) remains poorly understood. This work will broaden the knowledge base of academic and clinical professors, post-doctoral fellows, graduate and medical students regarding this vital biological process. Volumes in the Series
Author : Salem Chouaib
Publisher : Academic Press
ISBN 13 : 0128227575
Total Pages : 244 pages
Book Rating : 4.1/5 (282 download)
Download or read book Autophagy in Immune Response: Impact on Cancer Immunotherapy written by Salem Chouaib and published by Academic Press. This book was released on 2020-05-11 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: Autophagy in Immune Response: Impact on Cancer Immunotherapy focuses on the status and future directions of autophagy with respect to different aspects of its interaction with the immune system and immunotherapy. The book takes scientific research in autophagy a step further by presenting reputable information on the topic and offering integrated content with advancements in autophagy, from cell biology and biochemical research, to clinical treatments. This book is a valuable source for cancer researchers, oncologists, graduate students and several members of biomedical field who are interested in learning more on the relationship between autophagy and immunotherapies. - Presents updated knowledge on autophagy at the basic level and its potential use in cancer treatment - Offers the first book to cover autophagy at the interface of cell biology, immunology and tumor biology - Provides a wealth of information on the topic in a coherent and comprehensive collection of contributions by world renowned scientists and investigators
Author : Abhisek Bhattacharya
Publisher :
ISBN 13 :
Total Pages : 464 pages
Book Rating : 4.:/5 (942 download)
Download or read book Roles of Autophagy in Innate Immune Cells in Mediating Inflammation and Autoimmunity written by Abhisek Bhattacharya and published by . This book was released on 2014 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Keith B. Elkon
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3805580363
Total Pages : 219 pages
Book Rating : 4.8/5 (55 download)
Download or read book Apoptosis and Its Relevance to Autoimmunity written by Keith B. Elkon and published by Karger Medical and Scientific Publishers. This book was released on 2006 with total page 219 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume highlights the recent advances in the basic mechanisms of apoptosis and the application of that knowledge to understanding the impact of defective apoptosis or defective clearance of apoptotic cells on the immune function and the expression of
Author : Mauro D'Amato
Publisher : Springer Science & Business Media
ISBN 13 : 1461482569
Total Pages : 344 pages
Book Rating : 4.4/5 (614 download)
Download or read book Molecular Genetics of Inflammatory Bowel Disease written by Mauro D'Amato and published by Springer Science & Business Media. This book was released on 2013-10-05 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research in Crohn’s disease (CD) and ulcerative colitis (UC), together known as the inflammatory bowel diseases (IBD), has truly seen a revolution in the last 5-10 years. This book examines how these genetic discoveries have led to the identification of biological functions not previously associated with IBD pathophysiology (e.g. autophagy), how multiple genetic risk factors for IBD converge on given biological functions and that together the identified variants in these genes have predisposing and protective roles (e.g. the multiple variants in the receptor for the IL23 cytokine and its signaling cascade), and how having such a large number of known genetic risk factors has changed our understanding not only about the genetic and molecular overlap between CD and UC, but also between these diseases and other chronic inflammatory diseases (e.g. psoriasis, multiple sclerosis, type 1 diabetes and many others).
Author : Yehuda Shoenfeld
Publisher : John Wiley & Sons
ISBN 13 : 1118663438
Total Pages : 394 pages
Book Rating : 4.1/5 (186 download)
Download or read book Vaccines and Autoimmunity written by Yehuda Shoenfeld and published by John Wiley & Sons. This book was released on 2015-07-07 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: In light of the discovery of Autoimmune Syndrome Induced by Adjuvants, or ASIA, Vaccines and Autoimmunity explores the role of adjuvants – specifically aluminum in different vaccines – and how they can induce diverse autoimmune clinical manifestations in genetically prone individuals. Vaccines and Autoimmunity is divided into three sections; the first contextualizes the role of adjuvants in the framework of autoimmunity, covering the mechanism of action of adjuvants, experimental models of adjuvant induced autoimmune diseases, infections as adjuvants, the Gulf War Syndrome, sick-building syndrome (SBS), safe vaccines, toll-like receptors, TLRS in vaccines, pesticides as adjuvants, oil as adjuvant, mercury, aluminum and autoimmunity. The following section reviews literature on vaccines that have induced autoimmune conditions such as MMR and HBV, among others. The final section covers diseases in which vaccines were known to be the solicitor – for instance, systemic lupus erythematosus – and whether it can be induced by vaccines for MMR, HBV, HCV, and others. Edited by leaders in the field, Vaccines and Autoimmunity is an invaluable resource for advanced students and researchers working in pathogenic and epidemiological studies.
Author : Sujit Kumar Bhutia
Publisher : Springer Nature
ISBN 13 : 9811569304
Total Pages : 284 pages
Book Rating : 4.8/5 (115 download)
Download or read book Autophagy in tumor and tumor microenvironment written by Sujit Kumar Bhutia and published by Springer Nature. This book was released on 2020-10-24 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book deals with the paradoxical role of autophagy in tumor suppression and tumor promotion in cancer cells. Autophagy plays opposing, context-dependent roles in tumors; accordingly, strategies based on inhibiting or stimulating autophagy could offer as potential cancer therapies. The book elucidates the physiological role of autophagy in modulating cancer metastasis, which is the primary cause of cancer-associated mortality. Further, it reviews its role in the differentiation, development, and activation of multiple immune cells, and its potential applications in tumor immunotherapy. In addition, it examines the effect of epigenetic modifications of autophagy-associated genes in regulating tumor growth and therapeutic response and summarizes autophagy’s role in the development of resistance to a variety of anti-cancer drugs in cancer cells. In closing, it assesses autophagy as a potential therapeutic target for cancer treatment. Given its scope, the book offers a valuable asset for all oncologists and researchers who wish to understand the potential role of autophagy in tumor biology.
Author : Jos A.F. Op den Kamp
Publisher : Springer Science & Business Media
ISBN 13 : 3642731848
Total Pages : 474 pages
Book Rating : 4.6/5 (427 download)
Download or read book Membrane Biogenesis written by Jos A.F. Op den Kamp and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many individual aspects of the dynamics and assembly of biological membranes have been studied in great detail. Cell biological approaches, advanced genetics, biophysics and biochemistry have greatly contributed to an increase in our knowledge in this field.lt is obvious however, that the three major membrane constituents - lipids, proteins and carbohydrates- are studied, in most cases separately and that a coherent overview of the various aspects of membrane biogenesis is not readily available. The NATO Advanced Study Institute on "New Perspectives in the Dynamics of Assembly of Biomembranes" intended to provide such an overview: it was set up to teach students and specialists the achievements obtained in the various research areas and to try and integrate the numerous aspects of membrane assembly into a coherent framework. The articles in here reflect this. Statting with detailed contributions on phospholipid structure, dynamics, organization and biogenesis, an up to date overview of the basic, lipidic backbone of biomembranes is given. Extensive progress is made in the research on membrane protein biosynthesis. In particular the post- and co-translational modification processes of proteins, the mechanisms of protein translocation and the sorting mechanisms which are necessary to direct proteins to their final, intra - or extracellular destination have been characterized in detail. Modern genetic approaches were indispensable in this research area: gene cloning, hybrid protein construction, site directed mutagenesis and sequencing techniques elucidated many functional aspects of specific nucleic acid and amino acid sequences.
Author : William T. Jackson
Publisher : John Wiley & Sons
ISBN 13 : 1118677641
Total Pages : 364 pages
Book Rating : 4.1/5 (186 download)
Download or read book Autophagy, Infection, and the Immune Response written by William T. Jackson and published by John Wiley & Sons. This book was released on 2015-02-16 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: The relationship between infection and immunity and autophagy, a pathway of cellular homeostasis and stress response, has been a rapidly growing field of study over the last decade. While some cellular processes are pro- or anti-infection, autophagy has been proven to be both: a part of the innate immune response against some microbes, and a cellular pathway subverted by some pathogens to promote their own replication. Autophagy, Infection, and the Immune Response provides a unified overview of the roles of cellular autophagy during microbial infection. Introductory chapters ground the reader by delineating the autophagic pathway from a cellular perspective, and by listing assays available for measuring autophagy. Subsequent chapters address virus interactions with autophagy machinery, the various roles of autophagy parasitic infection, and interactions of bacteria with the autophagic pathway. Concluding chapters explore the relationships of autophagy to systemic immune responses, including antigen presentation, ER stress, and production of IFN-gamma. Designed as a resource for those interested in initiating studies on the relationship between autophagy and infection or immunity, Autophagy, Infection, and the Immune Response combines practical state-of the art technique descriptions with an overview of the wide variety of known interactions between pathogens and the autophagic pathway.
Author : Nima Rezaei
Publisher : Academic Press
ISBN 13 : 0323859763
Total Pages : 460 pages
Book Rating : 4.3/5 (238 download)
Download or read book Translational Autoimmunity, Volume 4 written by Nima Rezaei and published by Academic Press. This book was released on 2022-05-01 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the autoimmune diseases could affect different organs, Translational Autoimmunity: Autoimmune Diseases in Different Organs addresses the spectrum of autoimmune diseases. The fourth volume of Translational Immunology Series focuses on clinical and laboratory details of autoimmune diseases which are broadly categorized into two types of organ-specific autoimmune diseases and non-organ specific autoimmune diseases (also known as systemic autoimmune diseases). Autoimmune rheumatic diseases such as systemic lupus erythematosus and rheumatoid arthritis, autoimmune rheumatic diseases such as diabetes mellitus and thyroid diseases, autoimmune neurologic diseases such as multiple sclerosis, as well as autoimmune hepatobiliary diseases, autoimmune renal diseases and autoimmune cutaneous diseases as the subject of discussion in Translational Autoimmunity: Autoimmune Diseases in Different Organs. Comprises major parts that cover basic immunology, clinical aspects of autoimmunity, and translational immunology studies in autoimmunity Each and every key concept will be mentioned after an easy background is drawn and then, will be supported by a systematic appraisal of the most recent evidence Can help students at all the academic levels while applicable to scientists who work with autoimmunity Designed for learning, teaching, review and testing, practice, and research. Hence, it might be useful for students, teachers and instructors, physicians, and researchers
Author : Katerina Chatzidionysiou
Publisher : BoD – Books on Demand
ISBN 13 : 9535121340
Total Pages : 212 pages
Book Rating : 4.5/5 (351 download)
Download or read book Autoimmunity written by Katerina Chatzidionysiou and published by BoD – Books on Demand. This book was released on 2015-06-17 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: Autoimmunity is defined as an immune response against a self-antigen. This abnormal immune response can lead to tissue damage and to the development of autoimmune disease. From organ-specific autoimmune diseases, such as myasthenia gravis, to non-organ-specific, such as systemic lupus erythematosus, autoimmune diseases represent a heterogeneous group of disorders which affect approximately 6% of the population. The pathogenesis of many autoimmune diseases is complex and remains not completely understood. The aim of this book is to present current knowledge regarding pathogenic mechanisms of autoimmune diseases, clinical aspects of specific autoimmune diseases, like vitiligo, celiac disease and autoimmune liver disease, as well as insights regarding specific therapies.
