Autoimmune Hepatitis Unraveling The Complexities Of Immunology Liver Health And Holistic Care

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Autoimmune Hepatitis: Unraveling the Complexities of Immunology, Liver Health, and Holistic Care

Author : Dr. Spineanu Eugenia
Publisher : Dr. Spineanu Eugenia
ISBN 13 :
Total Pages : 143 pages
Book Rating : 4./5 ( download)

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Book Synopsis Autoimmune Hepatitis: Unraveling the Complexities of Immunology, Liver Health, and Holistic Care by : Dr. Spineanu Eugenia

Download or read book Autoimmune Hepatitis: Unraveling the Complexities of Immunology, Liver Health, and Holistic Care written by Dr. Spineanu Eugenia and published by Dr. Spineanu Eugenia. This book was released on 2024-11-03 with total page 143 pages. Available in PDF, EPUB and Kindle. Book excerpt: Could autoimmune hepatitis be the hidden cause behind chronic liver inflammation? Dive into this essential guide to understand the complexities of Autoimmune Hepatitis (AIH). CLARIFIES AIH CAUSES & PATHOGENESIS: Uncover how the immune system mistakenly targets the liver, leading to chronic inflammation. DIFFERENTIATES AIH SUBTYPES: Learn about the two main AIH types and their distinct markers and characteristics. SYMPTOMS & DIAGNOSTIC TECHNIQUES: Discover the tools and tests that help accurately diagnose AIH. IN-DEPTH TREATMENT INSIGHTS: Explore current and emerging therapies to manage this challenging autoimmune disease. HISTORICAL AND GENETIC PERSPECTIVES: Understand the genetic predispositions and milestones shaping AIH knowledge. This book provides a comprehensive view of autoimmune hepatitis, covering the underlying immune mechanisms, diagnostic strategies, and tailored treatments. Perfect for healthcare professionals and patients alike, it offers insights into managing AIH effectively while promoting liver health and understanding the disease’s progression.

Food-borne Viruses

Author : M. P. G. Koopmans
Publisher : Emerging Issues in Food Safety
ISBN 13 : 9781555814649
Total Pages : 0 pages
Book Rating : 4.8/5 (146 download)

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Book Synopsis Food-borne Viruses by : M. P. G. Koopmans

Download or read book Food-borne Viruses written by M. P. G. Koopmans and published by Emerging Issues in Food Safety. This book was released on 2008 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Food-borne viruses are recognized as a major health concern, but their distribution, definition, and impact are poorly understood. The volume Food-Borne Viruses goes a long way in correcting that problem. Written by leading scientists in the field, it brings together the latest knowledge on these viral strains, their detection and control, and associated challenges.

Essential Immunology

Author : Ivan Maurice Roitt
Publisher :
ISBN 13 :
Total Pages : 244 pages
Book Rating : 4.:/5 (42 download)

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Book Synopsis Essential Immunology by : Ivan Maurice Roitt

Download or read book Essential Immunology written by Ivan Maurice Roitt and published by . This book was released on 1971 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Improving Food Safety Through a One Health Approach

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309259363
Total Pages : 418 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis Improving Food Safety Through a One Health Approach by : Institute of Medicine

Download or read book Improving Food Safety Through a One Health Approach written by Institute of Medicine and published by National Academies Press. This book was released on 2012-09-10 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: Globalization of the food supply has created conditions favorable for the emergence, reemergence, and spread of food-borne pathogens-compounding the challenge of anticipating, detecting, and effectively responding to food-borne threats to health. In the United States, food-borne agents affect 1 out of 6 individuals and cause approximately 48 million illnesses, 128,000 hospitalizations, and 3,000 deaths each year. This figure likely represents just the tip of the iceberg, because it fails to account for the broad array of food-borne illnesses or for their wide-ranging repercussions for consumers, government, and the food industry-both domestically and internationally. A One Health approach to food safety may hold the promise of harnessing and integrating the expertise and resources from across the spectrum of multiple health domains including the human and veterinary medical and plant pathology communities with those of the wildlife and aquatic health and ecology communities. The IOM's Forum on Microbial Threats hosted a public workshop on December 13 and 14, 2011 that examined issues critical to the protection of the nation's food supply. The workshop explored existing knowledge and unanswered questions on the nature and extent of food-borne threats to health. Participants discussed the globalization of the U.S. food supply and the burden of illness associated with foodborne threats to health; considered the spectrum of food-borne threats as well as illustrative case studies; reviewed existing research, policies, and practices to prevent and mitigate foodborne threats; and, identified opportunities to reduce future threats to the nation's food supply through the use of a "One Health" approach to food safety. Improving Food Safety Through a One Health Approach: Workshop Summary covers the events of the workshop and explains the recommendations for future related workshops.

A Comprehensive Exploration of Autoimmune Hemolytic Anemia and Holistic Well-being

Author : Dr. Spineanu Eugenia
Publisher : Dr. Spineanu Eugenia
ISBN 13 :
Total Pages : 163 pages
Book Rating : 4./5 ( download)

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Book Synopsis A Comprehensive Exploration of Autoimmune Hemolytic Anemia and Holistic Well-being by : Dr. Spineanu Eugenia

Download or read book A Comprehensive Exploration of Autoimmune Hemolytic Anemia and Holistic Well-being written by Dr. Spineanu Eugenia and published by Dr. Spineanu Eugenia. This book was released on 2024-11-03 with total page 163 pages. Available in PDF, EPUB and Kindle. Book excerpt: What happens when the immune system turns against its own red blood cells? Discover the science behind Autoimmune Hemolytic Anemia (AIHA) in this comprehensive guide. EXPLAINS THE ROOT CAUSES: Understand how the immune system mistakenly attacks red blood cells, leading to hemolysis. DETAILED CLASSIFICATION OF AIHA SUBTYPES: Learn about Warm AIHA, Cold Agglutinin Disease, and more. SYMPTOMS AND DIAGNOSIS INSIGHTS: Recognize the signs and diagnostic approaches to detect AIHA early. DISCUSSION ON TREATMENT STRATEGIES: Explore medical and supportive treatments to manage this complex condition. EPIDEMIOLOGY AND RISK FACTORS: Gain insight into who is most affected by AIHA and the factors involved. This book is an essential resource for those seeking to understand AIHA, providing a deep dive into its causes, subtypes, and management options. Ideal for healthcare professionals, students, and anyone affected by AIHA, it demystifies this rare autoimmune disorder for better awareness and care.

The Autoimmune Fix

Author : Tom O'Bryan
Publisher : Rodale
ISBN 13 : 162336700X
Total Pages : 354 pages
Book Rating : 4.6/5 (233 download)

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Book Synopsis The Autoimmune Fix by : Tom O'Bryan

Download or read book The Autoimmune Fix written by Tom O'Bryan and published by Rodale. This book was released on 2016-09-20 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: Do you have crud in the blood? Millions of people suffer from autoimmunity whether they know it or not. The root cause of most weight gain, brain and mood problems, and fatigue, autoimmunity can take years--or even decades--for symptoms and a clear diagnosis to arise. Through years of research, Dr. Tom O’Bryan has discovered that autoimmunity is actually a spectrum, and many people experiencing general malaise are already on it. And while autoimmune diseases, such as Alzheimer’s, Multiple Sclerosis, osteoporosis, diabetes, and lupus, have become the third leading cause of death behind heart disease and cancer, many people affected are left in the dark. The good news is that many autoimmune conditions can be reversed through a targeted protocol designed to heal the autoimmune system, 70 percent of which is located in the gut. The Autoimmune Fix includes two comprehensive 3-week plans: In the first 3 weeks, you’ll follow a Paleo-inspired diet during which you cut out gluten, sweets, and dairy--the three primary culprits behind autoimmunity. Once the dietary changes have been addressed, The Autoimmune Fix focuses on the other causes of autoimmunity such as genetics, other dietary issues, and microbiome. The Autoimmune Fix provides a practical and much-needed guide to navigating these increasingly common conditions to help you feel better and develop a plan that works for you.

Curing Courtney

Author : Denise Gabay Otten
Publisher : Manifesting Life Publishing
ISBN 13 : 9780988646124
Total Pages : 198 pages
Book Rating : 4.6/5 (461 download)

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Book Synopsis Curing Courtney by : Denise Gabay Otten

Download or read book Curing Courtney written by Denise Gabay Otten and published by Manifesting Life Publishing. This book was released on 2012-12-01 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt: Curing Courtney is the empowering true story of a mother and daughter's triumph over the deadly autoimmune hepatitis that threatened to take the life of 7-year-old Courtney. After five years of treatment by some of the best pediatric hepatologists in New York City, the doctors told Courtney's mom, "The meds aren't working." The next step for 12-year-old Courtney was a leukemia-type drug and a possible liver transplant. Frustrated and angry that the doctors had stolen Courtney's childhood with their standard protocol that failed and the side-effects of high doses of prednisone which made little Courtney overweight and excessively hairy, Denise Otten took it upon herself to find an alternative treatment. Thanks to scientifically proven nutraceuticals and vitamins, plus a baseball autographed by Yankees star Derek Jeter, Courtney went into remission in a matter of months and is now a slim, beautiful, teenage athlete.

Beat Autoimmune

Author : Palmer Kippola
Publisher : Citadel Press
ISBN 13 : 0806538953
Total Pages : 385 pages
Book Rating : 4.8/5 (65 download)

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Book Synopsis Beat Autoimmune by : Palmer Kippola

Download or read book Beat Autoimmune written by Palmer Kippola and published by Citadel Press. This book was released on 2019-04-30 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reverse your negative health trajectory and start the journey towards healing and resilient health with Palmer Kippola’s groundbreaking plan to erase the effects of autoimmune disease. “An empowering and actionable guidebook that simplifies the steps back to health. Highly recommended!” —Izabella Wentz, PharmD, FASCP and #1 New York Times bestselling author of Hashimoto's Protocol Palmer Kippola is on a mission to make autoimmune disease history. When she was diagnosed with Multiple Sclerosis at age 19, she began a journey toward healing that resulted in a complete reversal of her symptoms. Now, with the help of leading medical experts, including renowned specialists in immunology and longevity from UCLA and Stanford medical schools, as well as leading practitioners in the field of autoimmunity and functional medicine, Kippola wants to help you find freedom from disease too. This comprehensive book is the first to explore all six of the critical lifestyle factors that are the root causes of autoimmune conditions—and the sources of regaining health: * Discover the foods that can trigger disease as well as healthy solutions to fit your personal nutritional profile *Explore the impact of common, often-undiagnosed infections and ways to optimize your immunity naturally *Learn how gut health is the key to recovery *Gain insight on how hormone imbalances can disrupt healing and how to assess your hormone levels *Eliminate environmental toxins in your home and body, and learn how to live a detox lifestyle *Reduce stress and build resilience Drawing on her own inspiring return to resilient health, as well as the healing stories of a dozen medical doctors and practitioners, plus years of research with autoimmune experts, Palmer Kippola gives readers the tools to beat autoimmune disease—and the hope that relief and healing are possible. “An excellent resource for those who want to use an integrative and functional medicine approach to support their healing journey!” —Terry Wahls, MD, author of The Wahls Protocol: A Radical New Way to Treat All Chronic Autoimmune Conditions Using Paleo Principles

Immunopharmacology

Author : Manzoor M. Khan
Publisher : Springer Science & Business Media
ISBN 13 : 0387779760
Total Pages : 275 pages
Book Rating : 4.3/5 (877 download)

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Book Synopsis Immunopharmacology by : Manzoor M. Khan

Download or read book Immunopharmacology written by Manzoor M. Khan and published by Springer Science & Business Media. This book was released on 2008-12-19 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the past decades, with the introduction of the recombinant DNA, hybridoma and transgenic technologies there has been an exponential evolution in understanding the pathogenesis, diagnosis and treatment of a large number of human diseases. The technologies are evident with the development of cytokines and monoclonal antibodies as therapeutic agents and the techniques used in gene therapy. Immunopharmacology is that area of biomedical sciences where immunology, pharmacology and pathology overlap. It concerns the pharmacological approach to the immune response in physiological as well as pathological events. This goals and objectives of this textbook are to emphasize the developments in immunology and pharmacology as they relate to the modulation of immune response. The information includes the pharmacology of cytokines, monoclonal antibodies, mechanism of action of immune-suppressive agents and their relevance in tissue transplantation, therapeutic strategies for the treatment of AIDS and the techniques employed in gene therapy. The book is intended for health care professional students and graduate students in pharmacology and immunology.

Equity, Social Determinants and Public Health Programmes

Author : World Health Organization
Publisher : World Health Organization
ISBN 13 : 9241563974
Total Pages : 302 pages
Book Rating : 4.2/5 (415 download)

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Book Synopsis Equity, Social Determinants and Public Health Programmes by : World Health Organization

Download or read book Equity, Social Determinants and Public Health Programmes written by World Health Organization and published by World Health Organization. This book was released on 2010 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: 1. Introduction and methods of work.-- 2. Alcohol: equity and social determinants.-- 3. Cardiovascular disease: equity and social determinants.-- 4. Health and nutrition of children: equity and social determinants.-- 5. Diabetes: equity and social determinants.-- 6. Food safety: equity and social determinants.-- 7. Mental disorders: equity and social determinants.-- 8. Neglected tropical diseases: equity and social determinants.-- 9. Oral health: equity and social determinants.-- 10. Unintended pregnancy and pregnancy outcome: equity and social determinants.-- 11. Tobacco use: equity and social determinants.-- 12. Tuberculosis: the role of risk factors and social determinants.-- 13. Violence and unintentional injury: equity and social determinants.-- 14. Synergy for equity.

The Biopsychosocial Model of Health and Disease

Author : Derek Bolton
Publisher : Springer
ISBN 13 : 3030118991
Total Pages : 157 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis The Biopsychosocial Model of Health and Disease by : Derek Bolton

Download or read book The Biopsychosocial Model of Health and Disease written by Derek Bolton and published by Springer. This book was released on 2019-03-28 with total page 157 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book is a systematic update of the philosophical and scientific foundations of the biopsychosocial model of health, disease and healthcare. First proposed by George Engel 40 years ago, the Biopsychosocial Model is much cited in healthcare settings worldwide, but has been increasingly criticised for being vague, lacking in content, and in need of reworking in the light of recent developments. The book confronts the rapid changes to psychological science, neuroscience, healthcare, and philosophy that have occurred since the model was first proposed and addresses key issues such as the model’s scientific basis, clinical utility, and philosophical coherence. The authors conceptualise biology and the psychosocial as in the same ontological space, interlinked by systems of communication-based regulatory control which constitute a new kind of causation. These are distinguished from physical and chemical laws, most clearly because they can break down, thus providing the basis for difference between health and disease. This work offers an urgent update to the model’s scientific and philosophical foundations, providing a new and coherent account of causal interactions between the biological, the psychological and social.

Molecular Epidemiology

Author : Paul A. Schulte
Publisher : Academic Press
ISBN 13 : 0323138578
Total Pages : 609 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis Molecular Epidemiology by : Paul A. Schulte

Download or read book Molecular Epidemiology written by Paul A. Schulte and published by Academic Press. This book was released on 2012-12-02 with total page 609 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book will serve as a primer for both laboratory and field scientists who are shaping the emerging field of molecular epidemiology. Molecular epidemiology utilizes the same paradigm as traditional epidemiology but uses biological markers to identify exposure, disease or susceptibility. Schulte and Perera present the epidemiologic methods pertinent to biological markers. The book is also designed to enumerate the considerations necessary for valid field research and provide a resource on the salient and subtle features of biological indicators.

The Emperor of All Maladies

Author : Siddhartha Mukherjee
Publisher : Simon and Schuster
ISBN 13 : 1439170916
Total Pages : 624 pages
Book Rating : 4.4/5 (391 download)

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Book Synopsis The Emperor of All Maladies by : Siddhartha Mukherjee

Download or read book The Emperor of All Maladies written by Siddhartha Mukherjee and published by Simon and Schuster. This book was released on 2011-08-09 with total page 624 pages. Available in PDF, EPUB and Kindle. Book excerpt: Winner of the Pulitzer Prize and a documentary from Ken Burns on PBS, this New York Times bestseller is “an extraordinary achievement” (The New Yorker)—a magnificent, profoundly humane “biography” of cancer—from its first documented appearances thousands of years ago through the epic battles in the twentieth century to cure, control, and conquer it to a radical new understanding of its essence. Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with—and perished from—for more than five thousand years. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out “war against cancer.” The book reads like a literary thriller with cancer as the protagonist. Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.

Biodiversity and Human Health

Author : Francesca Grifo
Publisher : Island Press
ISBN 13 : 9781559635004
Total Pages : 0 pages
Book Rating : 4.6/5 (35 download)

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Book Synopsis Biodiversity and Human Health by : Francesca Grifo

Download or read book Biodiversity and Human Health written by Francesca Grifo and published by Island Press. This book was released on 1997-02-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The implications of biodiversity loss for the global environment have been widely discussed, but only recently has attention been paid to its direct and serious effects on human health. Biodiversity loss affects the spread of human diseases, causes a loss of medical models, diminishes the supplies of raw materials for drug discovery and biotechnology, and threatens food production and water quality. Biodiversity and Human Health brings together leading thinkers on the global environment and biomedicine to explore the human health consequences of the loss of biological diversity. Based on a two-day conference sponsored by the National Institutes of Health, the National Science Foundation, and the Smithsonian Institution, the book opens a dialogue among experts from the fields of public health, biology, epidemiology, botany, ecology, demography, and pharmacology on this vital but often neglected concern. Contributors discuss the uses and significance of biodiversity to the practice of medicine today, and develop strategies for conservation of these critical resources. Topics examined include: the causes and consequences of biodiversity loss emerging infectious diseases and the loss of biodiversity the significance and use of both prescription and herbal biodiversity-derived remedies indigenous and local peoples and their health care systems sustainable use of biodiversity for medicine an agenda for the future In addition to the editors, contributors include Anthony Artuso, Byron Bailey, Jensa Bell, Bhaswati Bhattacharya, Michael Boyd, Mary S. Campbell, Eric Chivian, Paul Cox, Gordon Cragg, Andrew Dobson, Kate Duffy-Mazan, Robert Engelman, Paul Epstein, Alexandra S. Fairfield, John Grupenhoff, Daniel Janzen, Catherine A. Laughin, Katy Moran, Robert McCaleb, Thomas Mays, David Newman, Charles Peters, Walter Reid, and John Vandermeer. The book provides a common framework for physicians and biomedical researchers who wish to learn more about environmental concerns, and for members of the environmental community who desire a greater understanding of biomedical issues.

Ehlers-Danlos Syndrome: A Multidisciplinary Approach

Author : J.W.G. Jacobs
Publisher : IOS Press
ISBN 13 : 1614998787
Total Pages : 370 pages
Book Rating : 4.6/5 (149 download)

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Book Synopsis Ehlers-Danlos Syndrome: A Multidisciplinary Approach by : J.W.G. Jacobs

Download or read book Ehlers-Danlos Syndrome: A Multidisciplinary Approach written by J.W.G. Jacobs and published by IOS Press. This book was released on 2018-08-14 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Generalized hypermobility has been known since ancient times, and a clinical description of Ehlers-Danlos syndrome (EDS) is said to have first been recorded by Hippocrates in 400 BC. Hypermobility syndromes occur frequently, but the wide spectrum of possible symptoms, coupled with a relative lack of awareness and recognition, are the reason that they are frequently not recognized, or remain undiagnosed. This book is an international, multidisciplinary guide to hypermobility syndromes, and EDS in particular. It aims to create better awareness of hypermobility syndromes among health professionals, including medical specialists, and to be a guide to the management of such syndromes for patients and practitioners. It is intended for use in daily clinical practice rather than as a reference book for research or the latest developments, and has been written to be understandable for any healthcare worker or educated patient without compromise to the scientific content. The book is organized as follows: chapters on classifications and genetics are followed by chapters on individual types, organ (system) manifestations and complications, and finally ethics and therapeutic strategies, with an appendix on surgery and the precautions which should attend it. A special effort has been made to take account of the perspective of the patient; two of the editors have EDS. The book will be of interest to patients with hypermobility syndromes and their families, as well as to all those healthcare practitioners who may encounter such syndromes in the course of their work.

Temporomandibular Disorders

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309670489
Total Pages : 427 pages
Book Rating : 4.3/5 (96 download)

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Book Synopsis Temporomandibular Disorders by : National Academies of Sciences, Engineering, and Medicine

Download or read book Temporomandibular Disorders written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2020-07-01 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: Temporomandibular disorders (TMDs), are a set of more than 30 health disorders associated with both the temporomandibular joints and the muscles and tissues of the jaw. TMDs have a range of causes and often co-occur with a number of overlapping medical conditions, including headaches, fibromyalgia, back pain and irritable bowel syndrome. TMDs can be transient or long-lasting and may be associated with problems that range from an occasional click of the jaw to severe chronic pain involving the entire orofacial region. Everyday activities, including eating and talking, are often difficult for people with TMDs, and many of them suffer with severe chronic pain due to this condition. Common social activities that most people take for granted, such as smiling, laughing, and kissing, can become unbearable. This dysfunction and pain, and its associated suffering, take a terrible toll on affected individuals, their families, and their friends. Individuals with TMDs often feel stigmatized and invalidated in their experiences by their family, friends, and, often, the health care community. Misjudgments and a failure to understand the nature and depths of TMDs can have severe consequences - more pain and more suffering - for individuals, their families and our society. Temporomandibular Disorders: Priorities for Research and Care calls on a number of stakeholders - across medicine, dentistry, and other fields - to improve the health and well-being of individuals with a TMD. This report addresses the current state of knowledge regarding TMD research, education and training, safety and efficacy of clinical treatments of TMDs, and burden and costs associated with TMDs. The recommendations of Temporomandibular Disorders focus on the actions that many organizations and agencies should take to improve TMD research and care and improve the overall health and well-being of individuals with a TMD.

Consolidated Guidelines on the Use of Antiretroviral Drugs for Treating and Preventing HIV Infection

Author : World Health Organization
Publisher :
ISBN 13 : 9789241549684
Total Pages : 429 pages
Book Rating : 4.5/5 (496 download)

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Book Synopsis Consolidated Guidelines on the Use of Antiretroviral Drugs for Treating and Preventing HIV Infection by : World Health Organization

Download or read book Consolidated Guidelines on the Use of Antiretroviral Drugs for Treating and Preventing HIV Infection written by World Health Organization and published by . This book was released on 2016 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: These guidelines provide guidance on the diagnosis of human immunodeficiency virus (HIV) infection, the use of antiretroviral (ARV) drugs for treating and preventing HIV infection and the care of people living with HIV. They are structured along the continuum of HIV testing, prevention, treatment and care. This edition updates the 2013 consolidated guidelines on the use of antiretroviral drugs following an extensive review of evidence and consultations in mid-2015, shared at the end of 2015, and now published in full in 2016. It is being published in a changing global context for HIV and for health more broadly.