Atlas Of Experimental Toxicological Pathology

Download Atlas Of Experimental Toxicological Pathology full books in PDF, epub, and Kindle. Read online Atlas Of Experimental Toxicological Pathology ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!

Atlas of Experimental Toxicological Pathology

Author : C. Gopinath
Publisher : Springer Science & Business Media
ISBN 13 : 9400931891
Total Pages : 448 pages
Book Rating : 4.4/5 (9 download)

DOWNLOAD NOW!

Book Synopsis Atlas of Experimental Toxicological Pathology by : C. Gopinath

Download or read book Atlas of Experimental Toxicological Pathology written by C. Gopinath and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our aim in producing a colour atlas of toxicological guidelines itemize the investigations to be carried out pathology was to present a catalogue of histopathologi during the course of the study and they normally include: cal lesions which we had encountered over the years in clinical observations and behaviour; food intake and body various laboratory animal species exposed to a vast weight measurements; serum biochemistry; haema range of pharmaceuticals, agrochemicals and industrial tology; ECG and ophthalmology. At the end of a study, chemicals. While we believe a colour atlas is the ideal full macroscopic and microscopic examinations of the way to share our experiences with others, it quickly organ weight analyses together with tissues are essen became clear to us that for the atlas to be meaningful tial. By far the greater part of the material used in this the associated text must be comprehensive and contain book is from toxicity studies conducted in recent years ample literature references. and performed in compliance with the Good Laboratory The atlas is intended for both the trainee and the Practice standards of governmental regulatory bodies in experienced toxicological pathologist working with lab Europe, Japan and North America. oratory animals in the pharmaceutical, agrochemical or Toxicity studies are commonly carried out in rats, chemical environment.

Atlas of Toxicological Pathology

Author : Chirukandath Gopinath
Publisher : Springer
ISBN 13 : 1627039988
Total Pages : 291 pages
Book Rating : 4.6/5 (27 download)

DOWNLOAD NOW!

Book Synopsis Atlas of Toxicological Pathology by : Chirukandath Gopinath

Download or read book Atlas of Toxicological Pathology written by Chirukandath Gopinath and published by Springer. This book was released on 2014-05-13 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: This atlas contains more than 700 illustrations that the authors have collected over the years as well as references and information pertaining to recently developed drug classes, including biologics. It is a useful bench reference for practicing pathologists and may also be used as a reference text by other experts from related fields. The atlas is organised into different chapters based on systemic pathology. Each chapter has illustrations with legends, and the atlas includes some rare examples of unique lesions found during toxicity studies over many years.

Background Lesions in Laboratory Animals E-Book

Author : Elizabeth Fiona McInnes
Publisher : Elsevier Health Sciences
ISBN 13 : 0702049247
Total Pages : 141 pages
Book Rating : 4.7/5 (2 download)

DOWNLOAD NOW!

Book Synopsis Background Lesions in Laboratory Animals E-Book by : Elizabeth Fiona McInnes

Download or read book Background Lesions in Laboratory Animals E-Book written by Elizabeth Fiona McInnes and published by Elsevier Health Sciences. This book was released on 2011-10-24 with total page 141 pages. Available in PDF, EPUB and Kindle. Book excerpt: Background Lesions in Laboratory Animals will be an invaluable aid to pathologists needing to recognize background and incidental lesions while examining slides taken from laboratory animals in acute and chronic toxicity studies, or while examining exotic species in a diagnostic laboratory. It gives clear descriptions and illustrations of the majority of background lesions likely to be encountered. Many of the lesions covered are unusual and can be mistaken for treatment-related findings in preclinical toxicity studies. The Atlas has been prepared with contributions from experienced toxicological pathologists who are specialists in each of the laboratory animal species covered and who have published extensively in these areas. - over 600 high-definition, top-quality color photographs of background lesions found in rats, mice, dogs, minipigs, non-human primates, hamsters, guinea pigs and rabbits - a separate chapter on lesions in the reproductive systems of all laboratory animals written by Dr Dianne Creasy, a world expert on testicular lesions in laboratory animals - a chapter on common artifacts that may be observed in histological glass slides - extensive references to each lesion described - aging lesions encountered in all laboratory animal species, particularly in rats in mice which are used for carcinogenicity studies

The Illustrated Dictionary of Toxicologic Pathology and Safety Science

Author : Pritam S. Sahota
Publisher : CRC Press
ISBN 13 : 0429658060
Total Pages : 672 pages
Book Rating : 4.4/5 (296 download)

DOWNLOAD NOW!

Book Synopsis The Illustrated Dictionary of Toxicologic Pathology and Safety Science by : Pritam S. Sahota

Download or read book The Illustrated Dictionary of Toxicologic Pathology and Safety Science written by Pritam S. Sahota and published by CRC Press. This book was released on 2019-04-26 with total page 672 pages. Available in PDF, EPUB and Kindle. Book excerpt: There has been a growing interest in toxicologic pathology, especially as related to its impact on the safety assessment of pharmaceuticals and chemicals, and in drug development. Thus, there is a growing need for an Illustrated Dictionary of Toxicology Pathology and Safety Science (IDTP) that this dictionary aims to fill. The language of toxicologic pathology may be less familiar to a broad range of safety scientists, especially those involved in the safety evaluation of pharmaceuticals and chemicals. The IDTP format provides the brevity and clarity that the user is not likely to receive in a textbook, even if adequately indexed. With the inclusion of descriptions for terms used in toxicology, drug metabolism/pharmacokinetics, and regulatory science, the scope of the IDTP is considerably broadened and decidedly unique in its appeal to all safety scientists. With over 800 photos and illustrations to provide visual context,* an important aim of the IDTP is to present pathological changes as reference examples for terminology, nomenclature, and term descriptions for the entry entry-level as well as seasoned toxicologic pathologist. It will also aid students and non-pathology specialists such as study directors, senior toxicology report reviewers, scientific management of contract research organizations, regulatory agencies, and drug development companies to better understand the biological significance of tissue changes. The IDTP provides a single reference volume for these users to further their understanding and appreciation of biologically significant pathology findings. The IDTP consists of four major areas: 1. A-Z Dictionary of Pathology encompassing all organ systems, together with relevant non-pathology terms supported by references in "For Further Reading" sections. 2. Appendix 1: An Overviews of Drug Development, Nonclinical Safety & Toxicologic Pathology, and Important/Special Topics. 3. Appendix 2: Diagnostic Criteria of for Proliferative Proliferative Lesions in Rodents (Rat and Mouse) and Selected Non-Rodent Laboratory Species containing illustrations with detailed references and links to source material. 4) Appendix 3: Mini-Atlas of Organ System Anatomy and Histology to help re-acquaint the non-pathologist safety scientist with many normal anatomical structures. The editors and contributing scientists (board-certified veterinary pathologists, board-certified toxicologists, allied health safety scientists, health regulatory representatives) have experience from bench-level pathology and toxicology to managing global preclinical safety units in leading pharmaceutical companies. They have considerable experience mentoring pharmaceutical industry project team members, interacting with industry clinicians and representatives of decision-making bodies within the industry, as well as with global health authorities, such as the FDA and EMA. These activities convinced them of the necessity for and usefulness of the IDTP. As experts in their field, they have undertaken the hard work of writing and compiling the information, making the IDTP an exceptional, go-to reference. *Illustrations Editor: Gregory Argentieri

Target Organ Pathology

Author : J. Turton
Publisher : CRC Press
ISBN 13 : 9780748401567
Total Pages : 508 pages
Book Rating : 4.4/5 (15 download)

DOWNLOAD NOW!

Book Synopsis Target Organ Pathology by : J. Turton

Download or read book Target Organ Pathology written by J. Turton and published by CRC Press. This book was released on 1997-10-06 with total page 508 pages. Available in PDF, EPUB and Kindle. Book excerpt: The major organs of the body are targets for chemically-induced effects in animals and humans. This book reviews the mechanisms of these toxic effects and the structure/functional changes which occur in the target organ tissues as a result.

Toxicologic Pathology

Author : Pritam S. Sahota
Publisher : CRC Press
ISBN 13 : 1439872120
Total Pages : 987 pages
Book Rating : 4.4/5 (398 download)

DOWNLOAD NOW!

Book Synopsis Toxicologic Pathology by : Pritam S. Sahota

Download or read book Toxicologic Pathology written by Pritam S. Sahota and published by CRC Press. This book was released on 2013-04-09 with total page 987 pages. Available in PDF, EPUB and Kindle. Book excerpt: As drug development shifts over time to address unmet medical needs and more targeted therapies are developed, previously unseen pharmacological or off-target effects may occur in treatment. Designed to provide practical information for the bench toxicologic pathologist working in pharmaceutical drug research, Toxicologic Pathology: Nonclinical Saf

Animal Models in Toxicology

Author : Shayne C. Gad
Publisher : CRC Press
ISBN 13 : 142001420X
Total Pages : 950 pages
Book Rating : 4.4/5 (2 download)

DOWNLOAD NOW!

Book Synopsis Animal Models in Toxicology by : Shayne C. Gad

Download or read book Animal Models in Toxicology written by Shayne C. Gad and published by CRC Press. This book was released on 2006-10-30 with total page 950 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reflecting more than a decade's worth of changes, Animal Models in Toxicology, Second Edition is a practical guide to the common statistical problems encountered in toxicology and the methodologies that are available to solve them. The book presents a historical review of the use of animal models and an overview of broad considerations of me

Biopsy of Bone in Internal Medicine: An Atlas and Sourcebook

Author : Reiner Bartl
Publisher : Springer Science & Business Media
ISBN 13 : 9401122229
Total Pages : 239 pages
Book Rating : 4.4/5 (11 download)

DOWNLOAD NOW!

Book Synopsis Biopsy of Bone in Internal Medicine: An Atlas and Sourcebook by : Reiner Bartl

Download or read book Biopsy of Bone in Internal Medicine: An Atlas and Sourcebook written by Reiner Bartl and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive book, lavishly illustrated with over 700 colour pictures, addresses the subject of bone in internal medicine. It is based on biopsies of bone and first describes the normal range of physiological findings in iliac crest biopsies in young, middle-aged and elderly individuals. The book then deals systematically with the osseous disorders most frequently encountered in internal medicine, and some that would be considered in the differential diagnosis. Numerous up-to-date references are included. The clinical applications of biopsies of bone are emphasized as well as their clinical interpretation; sections on histomorphometry and functional aspects of bone cells are also included. The book will be of particular interest to specialists in internal medicine, endocrinology, nephrology, haematology and oncology, as well as being a bench manual for the practising pathologist.

Information Resources in Toxicology

Author : P.J. Bert Hakkinen
Publisher : Elsevier
ISBN 13 : 008053466X
Total Pages : 953 pages
Book Rating : 4.0/5 (85 download)

DOWNLOAD NOW!

Book Synopsis Information Resources in Toxicology by : P.J. Bert Hakkinen

Download or read book Information Resources in Toxicology written by P.J. Bert Hakkinen and published by Elsevier. This book was released on 2000-01-10 with total page 953 pages. Available in PDF, EPUB and Kindle. Book excerpt: Information Resources in Toxicology, Third Edition is a sourcebook for anyone who needs to know where to find toxicology information. It provides an up-to-date selective guide to a large variety of sources--books, journals, organizations, audiovisuals, internet and electronic sources, and more. For the Third Edition, the editors have selected, organized, and updated the most relevant information available. New information on grants and other funding opportunities, physical hazards, patent literature, and technical reports have also been added.This comprehensive, time-saving tool is ideal for toxicologists, pharmacologists, drug companies, testing labs, libraries, poison control centers, physicians, legal and regulatory professionals, and chemists. - Serves as an all-in-one resource for toxicology information - New edition includes information on publishers, grants and other funding opportunities, physical hazards, patent literature, and technical reports - Updated to include the latest internet and electronic sources, e-mail addresses, etc. - Provides valuable data about the new fields that have emerged within toxicological research; namely, the biochemical, cellular, molecular, and genetic aspects

Atlas of Serous Fluid Cytopathology

Author : A. Spriggs
Publisher : Springer Science & Business Media
ISBN 13 : 9400908490
Total Pages : 143 pages
Book Rating : 4.4/5 (9 download)

DOWNLOAD NOW!

Book Synopsis Atlas of Serous Fluid Cytopathology by : A. Spriggs

Download or read book Atlas of Serous Fluid Cytopathology written by A. Spriggs and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 143 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is hoped that this book may serve two purposes. felt that the resulting increase in size and expense of First it is intended for use at the bench. to help solve the book would not be justified. some of the problems of cell identification which The material was collected over many years and puzzle not only beginners. but even experienced we cannot individually acknowledge the great contri observers in the field of cytological diagnosis. Sec bution made by technical staff of the clinical cytology ondly we have reviewed the most significant previous laboratories who assisted the two authors to prepare publications. particularly those of the past 20 years. and stain the sl ides. Most of the electron micrographs so as to provide a source of reference. were made by or with the assistance of the late Denis Cytological diagnosis should not be isolated from W. Jerrome. and we are also grateful to Dr David histopathology. and many readers will regret the lack Ferguson for further help and advice with these. All of the immunocytochemical stains were done by Dr of cyto-histological correlation in our choice of photographs. Cells centrifuged out of suspension in Anna Ghosh. and Drs David Mason and Kevin Gatter pathological fluids bear very little resemblance to kindly commented on that part of the manuscript. their counterparts in tissue sections.

Comprehensive Toxicology

Author :
Publisher : Elsevier
ISBN 13 : 0081006128
Total Pages : 8639 pages
Book Rating : 4.0/5 (81 download)

DOWNLOAD NOW!

Book Synopsis Comprehensive Toxicology by :

Download or read book Comprehensive Toxicology written by and published by Elsevier. This book was released on 2017-12-01 with total page 8639 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Toxicology, Third Edition, Fifteen Volume Set discusses chemical effects on biological systems, with a focus on understanding the mechanisms by which chemicals induce adverse health effects. Organized by organ system, this comprehensive reference work addresses the toxicological effects of chemicals on the immune system, the hematopoietic system, cardiovascular system, respiratory system, hepatic toxicology, renal toxicology, gastrointestinal toxicology, reproductive and endocrine toxicology, neuro and behavioral toxicology, developmental toxicology and carcinogenesis, also including critical sections that cover the general principles of toxicology, cellular and molecular toxicology, biotransformation and toxicology testing and evaluation. Each section is examined in state-of-the-art chapters written by domain experts, providing key information to support the investigations of researchers across the medical, veterinary, food, environment and chemical research industries, and national and international regulatory agencies. Thoroughly revised and expanded to 15 volumes that include the latest advances in research, and uniquely organized by organ system for ease of reference and diagnosis, this new edition is an essential reference for researchers of toxicology. Organized to cover both the fundamental principles of toxicology and unique aspects of major organ systems Thoroughly revised to include the latest advances in the toxicological effects of chemicals on the immune system Features additional coverage throughout and a new volume on toxicology of the hematopoietic system Presents in-depth, comprehensive coverage from an international author base of domain experts

Paediatric Neoplasia

Author : S. Variend
Publisher : Springer Science & Business Media
ISBN 13 : 9401122245
Total Pages : 124 pages
Book Rating : 4.4/5 (11 download)

DOWNLOAD NOW!

Book Synopsis Paediatric Neoplasia by : S. Variend

Download or read book Paediatric Neoplasia written by S. Variend and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 124 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer is an important cause of death within the first 15 played an important role in assembling valuable data concerning some of the less common neoplasms. Such years of life. Many childhood cancers are fundamentally different from those arising in adults by virtue of patho sources of information, as well as those produced by large genesis, behaviour and response to therapy. One of the repositories of material (e.g. The American Armed Forces Institute of Pathology), are widely utilized throughout the great success stories of recent years has been the dramatic improvement in survival of children with many different text. types of cancer. This has been made possible largely is a field which is evolving fast on Paediatric neoplasia through the development and implementation of multimo several different fronts, and, against this backdrop, the dality treatment regimes, as well as increasingly accurate accompanying text can only provide a 'snapshot' account.

Spontaneous Pathology of the Laboratory Non-human Primate

Author : Alys Bradley
Publisher : Academic Press
ISBN 13 : 012813089X
Total Pages : 628 pages
Book Rating : 4.1/5 (281 download)

DOWNLOAD NOW!

Book Synopsis Spontaneous Pathology of the Laboratory Non-human Primate by : Alys Bradley

Download or read book Spontaneous Pathology of the Laboratory Non-human Primate written by Alys Bradley and published by Academic Press. This book was released on 2023-06-20 with total page 628 pages. Available in PDF, EPUB and Kindle. Book excerpt: Spontaneous Pathology of the Laboratory Non-human Primate serves as a "go to" resource for all pathologists working on primates in safety assessment studies. In addition, it helps diagnostic veterinary pathologists rule out spontaneous non-clinical disease pathologies when assigning cause of death to species in zoological collections. Primate species included are rhesus, cynomolgus macaques and marmosets. Multi-authored chapters are arranged by organ system, thus providing the necessary information for continued research.Pathologists often face a lack of suitable reference materials or historical data to determine if pathologic changes they are observing in monkeys are spontaneous or a consequence of other treatments or factors. - Contains color illustrations that depict the most common lesions to augment descriptions - Covers descriptions that are compliant with the International Harmonization of Nomenclature and Diagnostic Criteria (INHAND) guidelines set forth by the Society of Toxicologic Pathology (STP) - Provides pathologists with common terms that are compliant with the FDA's Standard for Exchange of Nonclinical Data (SEND) guidelines

Dieseases of the Wistar Rat

Author : Mary J Tucker
Publisher : CRC Press
ISBN 13 : 0748405216
Total Pages : 269 pages
Book Rating : 4.7/5 (484 download)

DOWNLOAD NOW!

Book Synopsis Dieseases of the Wistar Rat by : Mary J Tucker

Download or read book Dieseases of the Wistar Rat written by Mary J Tucker and published by CRC Press. This book was released on 1997-05-21 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text provides a complete account of this particular rat strain. The book includes extensive data on reproductive indices, congenital abnormalities, growth, clinical signs, mortality, organ weights and chemical pathology. The data are derived from around 9000 control animals used in toxicology studies of two weeks to two years duration, completed between 1960 and 1992, and include 24 two-year studies and one life-span study of a 51 month duration. These extended periods of study have shown that many diseases are seen more frequently in later years.; Diseases are dealt with by body system and include clinical signs, macroscopic features and histopathology illustrations of the important or unusual diseases. Incidence levels are provided for all diseases and these are compared with published data for other rat strains.

Histopathology of Preclinical Toxicity Studies

Author : Peter Greaves
Publisher : Elsevier
ISBN 13 : 0080471307
Total Pages : 962 pages
Book Rating : 4.0/5 (84 download)

DOWNLOAD NOW!

Book Synopsis Histopathology of Preclinical Toxicity Studies by : Peter Greaves

Download or read book Histopathology of Preclinical Toxicity Studies written by Peter Greaves and published by Elsevier. This book was released on 2007-03-23 with total page 962 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work covers effectively all aspects of drug-induced pathology that may be encountered within preclinical toxicity studies. It fills a gap in the pathology literature relating to the preclinical safety assessment of new medicines. It systematically describes, in one volume, both spontaneous and drug induced pathology on an organ by organ basis. Information relevant to understanding the nature of pathological changes in pre-clinical studies and assessment of their relevance to the clinical investigation of new drugs is also covered. Numerous colour photographs are included that highlight and embellish the histopathological features that are described. It also contains many pertinent references to both human and animal pathology forming an essential basis for the assessment of drug-induced pathology.NEW TO THE THIRD EDITION:* Covers drug induced pathology in preclinical (animal) studies and their relevance for patients or volunteers in clinical studies* General comments to each chapter about the relevance of pathological findings to humans* Provides essential information that can help decide the relevance of particular lesions for patients

Endocrine Toxicology

Author : C. K. Atterwill
Publisher : Cambridge University Press
ISBN 13 : 9780521402255
Total Pages : 504 pages
Book Rating : 4.4/5 (22 download)

DOWNLOAD NOW!

Book Synopsis Endocrine Toxicology by : C. K. Atterwill

Download or read book Endocrine Toxicology written by C. K. Atterwill and published by Cambridge University Press. This book was released on 1992-04-09 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first book to deal comprehensively with endocrine toxicology. It covers the whole spectrum of known toxicant effects on the endocrine system ranging from small disturbances in hormonal secretion to full endocrine neoplasia. In each chapter, internationally recognised authorities have addressed basic endocrine physiology, current techniques for studying endocrine toxicity in vivo and in vitro, known xenobiotic-induced toxicity phenomena and the latest scientific advances in understanding the underlying molecular and cellular events. Consideration is given to important issues such as dietary factors which influence endocrine toxicity, species differences in sensitivity to toxicants, and the toxicity of hormones and drugs. The volume provides a sound basis for understanding the scientific aspects of this complex and important area of toxicology and will be a useful source of information for all those working in this field.

Assessing Ocular Toxicology in Laboratory Animals

Author : Andrea B Weir
Publisher : Springer Science & Business Media
ISBN 13 : 1627031642
Total Pages : 327 pages
Book Rating : 4.6/5 (27 download)

DOWNLOAD NOW!

Book Synopsis Assessing Ocular Toxicology in Laboratory Animals by : Andrea B Weir

Download or read book Assessing Ocular Toxicology in Laboratory Animals written by Andrea B Weir and published by Springer Science & Business Media. This book was released on 2012-12-04 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ocular toxicity is routinely assessed in toxicology studies conducted for regulatory purposes. Ocular anatomy and physiology and the assessment of ocular toxicity itself can be challenging to scientists involved in the safety assessment of pharmaceuticals, pesticides and other agents. Anatomical and physiological differences between species can impact the nature of ocular effects observed following intended or unintended exposure of ocular tissues to xenobiotics. Ocular Toxicity in Laboratory Animals provides a concise reference addressing ocular anatomy and physiology across species that will enhance the design and interpretation of toxicology studies conducted for regulatory purposes. The book provides an overview of routine and advanced techniques that are used to assess ocular toxicity including slit lamp biomicroscopy, indirect ophthalmoscopy, electrophysiology and imaging methods for the anterior and posterior segments of the eye. Additionally, the book defines the regulatory expectations for pharmaceuticals intended to treat ocular diseases and for other non-pharmaceutical regulated chemicals. With contributions from experts in the field, Ocular Toxicity in Laboratory Animals is an authoritative, accessible guide for toxicologists and other scientists involved in conducting toxicology studies for regulatory purposes and/or reviewing data from such studies.