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Asymmetric Synthesis Of Beta Lactams
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Book Synopsis Asymmetric Synthesis of Beta-lactams by : Jeffrey M. McKenna
Download or read book Asymmetric Synthesis of Beta-lactams written by Jeffrey M. McKenna and published by . This book was released on 1994 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Beta-Lactams written by Bimal K. Banik and published by Springer. This book was released on 2017-05-11 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents an essential overview of beta-lactams and their medicinal value and use in the preparation of other biologically active compounds. Written by internationally respected authors, the individual chapters explore beta-lactams’ synthesis, their mechanism of formation, biological effects, and function as base materials for other heterocycles of major importance.
Book Synopsis Asymmetric Synthesis of [beta]-lactam Antibiotics by : Eric Brian Sjogren
Download or read book Asymmetric Synthesis of [beta]-lactam Antibiotics written by Eric Brian Sjogren and published by . This book was released on 1986 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis A Novel Methodology for the Asymmetric Synthesis of Beta-lactams and Beta-amino Acids by : Caroline Evans
Download or read book A Novel Methodology for the Asymmetric Synthesis of Beta-lactams and Beta-amino Acids written by Caroline Evans and published by . This book was released on 2012 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The first example of an intramolecular ester enolate-imine cyclisation reaction for the asymmetric synthesis of polycyclic ~-Iactams and cyclic ~-amino acid derivatives has been developed. In Chapter 1, the synthesis of monocyclic ~-Iactams using intermolecular ester enolate- imine cyclisation reactions is reviewed. The use of chiral auxiliaries contained within the ester or imino functionality to control the diastereoselectivity of the reaction is discussed, as well as enantioselective approaches. The utilization of this methodology for the synthesis of natural products such as Taxol is described, as well as the use of polymer support protocols to improve the efficiency of this reaction. In Chapter 2, the synthesis of an appropriate cyclisation substrate containing an ester and imino functionality with a chiral auxiliary fragment is reported. Appropriate conditions were established that enabled an intramolecular enolate-imine cyclisation reaction to be used for the synthesis of the tricyclic ~-Iactam benzocispentacin in good yield and excellent de. The formation of ~-amino ester side products was investigated and an explanation for the production of ~-Iactams as major products over their corresponding ~-amino esters is proposed. This protocol was then applied to the asymmetric synthesis of six benzocispentacin derivatives all with good yields and excellent de, with the configuration of one of these derivatives being confirmed by X-ray crystallography. A deprotection methodology was then established to afford their corresponding tricyclic NH-~-Iactams and cis and trans bicyclic ~-amino esters. In Chapter 3, the newly devised methodology was also applied to acyclic substrates for the synthesis of the antifungal cispentacin. The ability to access both cis- and transpentacin in both high yields and excellent de as monomers for foldamer synthesis is reported.
Book Synopsis The Organic Chemistry of B [beta]-lactams by : Gunda I. Georg
Download or read book The Organic Chemistry of B [beta]-lactams written by Gunda I. Georg and published by . This book was released on 1992 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Asymmetric Synthesis of Β-lactams by : Alan Daniel Brown
Download or read book Asymmetric Synthesis of Β-lactams written by Alan Daniel Brown and published by . This book was released on 1990 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Asymmetric Synthesis of Β-lactams by : Jeffrey M. McKenna
Download or read book Asymmetric Synthesis of Β-lactams written by Jeffrey M. McKenna and published by . This book was released on 1994 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Asymmetric Synthesis of [beta]-lactams and Their Applications to Taxoids and Nonprotein Amino Acids by : Young Hoon Park
Download or read book Asymmetric Synthesis of [beta]-lactams and Their Applications to Taxoids and Nonprotein Amino Acids written by Young Hoon Park and published by . This book was released on 1994 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Asymmetric Synthesis of [beta]-lactams for the Preparation of Bioactive Compounds by : Zhijun Wu
Download or read book Asymmetric Synthesis of [beta]-lactams for the Preparation of Bioactive Compounds written by Zhijun Wu and published by . This book was released on 1995 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis A Novel Methodology for the Asymmetric Synthesis of B[beta]-lactams and B[beta]-amino Acids by : Caroline Diana Evans
Download or read book A Novel Methodology for the Asymmetric Synthesis of B[beta]-lactams and B[beta]-amino Acids written by Caroline Diana Evans and published by . This book was released on 2012 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Asymmetric Synthesis of [beta]-lactam Derivatives by : Chun Ma
Download or read book Asymmetric Synthesis of [beta]-lactam Derivatives written by Chun Ma and published by . This book was released on 1992 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Asymmetric Synthesis of Azetidines and [beta]-lactams, and Their Applications in Organic Synthesis by : Mangzhu Zhao
Download or read book Asymmetric Synthesis of Azetidines and [beta]-lactams, and Their Applications in Organic Synthesis written by Mangzhu Zhao and published by . This book was released on 1991 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Asymmetric Synthesis of [alpha]-hydroxyl-4-alkyl-[beta]-lactams by : Chung-Ming Sun
Download or read book Asymmetric Synthesis of [alpha]-hydroxyl-4-alkyl-[beta]-lactams written by Chung-Ming Sun and published by . This book was released on 1995 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Asymmetric Synthesis of [alpha]-alkylated [alpha]-amino Acids and Stereoselective Synthesis of [beta]-lactams by : Xiangming Guan
Download or read book Asymmetric Synthesis of [alpha]-alkylated [alpha]-amino Acids and Stereoselective Synthesis of [beta]-lactams written by Xiangming Guan and published by . This book was released on 1991 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Heterocyclic Scaffolds I by : Bimal K. Banik
Download or read book Heterocyclic Scaffolds I written by Bimal K. Banik and published by Springer. This book was released on 2010-06-01 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: Contents: B. Alcaide ∙ P. Almendros: Novel Aspects on the Preparation of Spirocyclic and Fused Unsual β-Lactams.- S.S. Bari ∙ A. Bhalla: Spirocyclic β-Lactams: Synthesis and Biological Evaluation of Novel Heterocycles.- L. Troisi ∙ C. Granito ∙ E. Pindinelli: Novel and Recent Synthesis and Applications of β-Lactams.- C. Palomo ∙ M. Oiarbide: β-Lactams Ring Opening: A Useful Entry to Amino Acids and Relevant Nitrogen-Containing Compounds.- B. Mandal ∙ P. Ghosh ∙ B. Basu: Recent Approaches Towards Solid Phase Synthesis of β-Lactams.- A.Arrieta ∙ B. Lecea ∙ F.P. Cossio: Computational Studies on the Synthesis of β-Lactams Via [ 2+2] Thermal Cycloadditions.- B. K. Banik ∙ I. Banik ∙ F. F. Becker: Novel Anticancer β-Lactams
Book Synopsis A Catalytic Asymmetric Hydrogenation Approach Towards the Synthesis of Β-lactam Antibiotics by : Chin Yu Lim
Download or read book A Catalytic Asymmetric Hydrogenation Approach Towards the Synthesis of Β-lactam Antibiotics written by Chin Yu Lim and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Chemistry and Biology of Beta-Lactams by : Bimal Krishna Banik
Download or read book Chemistry and Biology of Beta-Lactams written by Bimal Krishna Banik and published by CRC Press. This book was released on 2024-11-07 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: Due to their medicinal activity and potential use as synthetic starting materials, studies on beta-lactams have increased significantly. This unique volume takes readers on a tour de force from the concept of antibiosis to the serendipity of antibiotics, evolution of beta‐lactam development, and molecular biology of antibiotic resistance. These areas of research have culminated in a deeper understanding of microbiology, particularly in the area of bacterial cell wall synthesis and recycling. Considerable work has been performed by chemists and biologists to continue updating their findings about beta-lactam synthesis. Features: • Stereoselective synthesis of monocyclic, bicyclic, and polycyclic beta-lactams • Microwave, ultrasound, and solid support-mediated preparation of beta-lactams • Diverse medicinal activities including anticancer activities of beta-lactams and products obtained from them • Nanoparticles, artificial intelligence, and dipole moments in beta-lactam science • Synthesis and mechanism of formation of polyaromatic beta-lactams