Astrocytes Cell Biology And Pathology Of Astrocytes

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Biology and Pathology of Astrocyte-Neuron Interactions

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Author : Sergey Fedoroff
Publisher : Springer Science & Business Media
ISBN 13 : 147579486X
Total Pages : 452 pages
Book Rating : 4.4/5 (757 download)

Book Synopsis Biology and Pathology of Astrocyte-Neuron Interactions by : Sergey Fedoroff

Download or read book Biology and Pathology of Astrocyte-Neuron Interactions written by Sergey Fedoroff and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is made up of papers presented at the Second International Altschul Symposium: Biology and Pathology of Astrocyte-Neuron Interactions. The symposium was held in Saskatoon, Canada at the University of Saskatchewn in May, 1992 in memory of Rudolf Altschul, a graduate of the University of Prague and a pioneer in the fields of the biology of the vascular and nervous systems. Dr. Altschul was Professor and Head of the Department of Anatomy at the University of Saskatchewan from 1955 to 1963. The Altschul Symposia were made possible by an endowment left by Anni Altschul and by other contributions. The symposia are held biennially. One of the greatest challenges for present day scientists is to uncover the mechanisms of brain function. Although cellular anatomy of the nervous system has already been well outlined and indeed was delineated by the beginning of the century, experimental analysis of the function of the brain is relatively recent. The framework of the brain is made up of stellate cells, the astrocytes, which are interconnected by means of their processes, thus presenting a meshwork through which the neurons send their axons, accompanied by oligodendrocytes. Microglia are distributed throughout the brain.

Astrocytes: Cell biology and pathology of astrocytes

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Author : Sergey Fedoroff
Publisher :
ISBN 13 :
Total Pages : 496 pages
Book Rating : 4.3/5 (91 download)

Book Synopsis Astrocytes: Cell biology and pathology of astrocytes by : Sergey Fedoroff

Download or read book Astrocytes: Cell biology and pathology of astrocytes written by Sergey Fedoroff and published by . This book was released on 1986 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: Band 3.

Astrocyte

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Author : Maria Teresa Gentile
Publisher : BoD – Books on Demand
ISBN 13 : 9535138855
Total Pages : 244 pages
Book Rating : 4.5/5 (351 download)

Book Synopsis Astrocyte by : Maria Teresa Gentile

Download or read book Astrocyte written by Maria Teresa Gentile and published by BoD – Books on Demand. This book was released on 2018-03-21 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: A team of authors from prestigious academic schools contributed to draw up a project that would give a detailed account of astrocyte's morphology and physiology, examining thoroughly all the astrocyte's types; giving an accurate description of their morphology, location, function in the brain; and illustrating their physiology and pathology in terms of dealing with neurons through "gliotransmitters," ionic channels, and membrane receptors expression. This book gives an overview of the crucial role of astrocytes in the physiology of the CNS and in the pathogenesis of several CNS disorders suggesting that the shift from a neurocentric view to one that incorporates astrocytes in disease models for drug discovery is a critical step in renewing drug development strategies to treat neurodegenerative diseases.

Astrocytes Pt 3: Biochemistry, Physiology, and Pharmacology of Astrocytes

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Author : Sergey Fedorff
Publisher : Elsevier
ISBN 13 : 0323148557
Total Pages : 487 pages
Book Rating : 4.3/5 (231 download)

Book Synopsis Astrocytes Pt 3: Biochemistry, Physiology, and Pharmacology of Astrocytes by : Sergey Fedorff

Download or read book Astrocytes Pt 3: Biochemistry, Physiology, and Pharmacology of Astrocytes written by Sergey Fedorff and published by Elsevier. This book was released on 2012-12-02 with total page 487 pages. Available in PDF, EPUB and Kindle. Book excerpt: Astrocytes: Cell Biology and Pathology of Astrocytes, Volume 3 deals with the involvement of astrocytes in neurological and neuropathological states of brain function. This volume discusses the expression of astrocyte-specific immunological markers and plasma membrane structures; the dynamics of the cytoskeleton and cell cycle; and the reactivity to injury and response of astrocytes in selected pathological and genetic states. The text also aims to inspire new ideas and research on astrocyte functions as well as on the pathogenesis of neurological disorders. Neuroscientists, cell biologists, clinicians, neuropathologists, and pediatric neurologists will find the book invaluable.

Astrocytes in (Patho)Physiology of the Nervous System

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Author : Vladimir Parpura
Publisher : Springer Science & Business Media
ISBN 13 : 0387794921
Total Pages : 701 pages
Book Rating : 4.3/5 (877 download)

Book Synopsis Astrocytes in (Patho)Physiology of the Nervous System by : Vladimir Parpura

Download or read book Astrocytes in (Patho)Physiology of the Nervous System written by Vladimir Parpura and published by Springer Science & Business Media. This book was released on 2008-12-11 with total page 701 pages. Available in PDF, EPUB and Kindle. Book excerpt: Astrocytes were the original neuroglia that Ramón y Cajal visualized in 1913 using a gold sublimate stain. This stain targeted intermediate filaments that we now know consist mainly of glial fibrillary acidic protein, a protein used today as an astrocytic marker. Cajal described the morphological diversity of these cells with some ast- cytes surrounding neurons, while the others are intimately associated with vasculature. We start the book by discussing the heterogeneity of astrocytes using contemporary tools and by calling into question the assumption by classical neuroscience that neurons and glia are derived from distinct pools of progenitor cells. Astrocytes have long been neglected as active participants in intercellular communication and information processing in the central nervous system, in part due to their lack of electrical excitability. The follow up chapters review the “nuts and bolts” of ast- cytic physiology; astrocytes possess a diverse assortment of ion channels, neu- transmitter receptors, and transport mechanisms that enable the astrocytes to respond to many of the same signals that act on neurons. Since astrocytes can detect chemical transmitters that are released from neurons and can release their own extracellular signals there is an increasing awareness that they play physiological roles in regulating neuronal activity and synaptic transmission. In addition to these physiological roles, it is becoming increasingly recognized that astrocytes play critical roles during pathophysiological states of the nervous system; these states include gliomas, Alexander disease, and epilepsy to mention a few.

The Biology of Glial Cells: Recent Advances

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Author : Ishan Patro
Publisher : Springer Nature
ISBN 13 : 9811683131
Total Pages : 763 pages
Book Rating : 4.8/5 (116 download)

Book Synopsis The Biology of Glial Cells: Recent Advances by : Ishan Patro

Download or read book The Biology of Glial Cells: Recent Advances written by Ishan Patro and published by Springer Nature. This book was released on 2022-04-09 with total page 763 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews the role of glial cells (astrocytes, microglia, oligodendroglia, satellite cells, and Schwann cells) in neuronal health and diseases. It discusses the latest advances in understanding their origin, differentiation, and hemostasis. The book also examines the role of microglial cells in central nervous system (CNS) development, maintenance, and synaptic plasticity. Further, the book presents the functions of astrocytes in healthy CNS and their critical role in CNS disorders, including Parkinson's and Alzheimer's diseases. Notably, the book describes the pathobiology, molecular pathogenesis, stem cells, and imaging characteristics of gliomas. It defines the role of glial cells in regulating iron homeostasis and their effect on the neurodegeneration of neurons. Lastly, it covers the structure, function, and pathology of oligodendrocytes and their role in neuronal health and disease.

Brain Neurotrauma

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Author : Firas H. Kobeissy
Publisher : CRC Press
ISBN 13 : 1466565993
Total Pages : 718 pages
Book Rating : 4.4/5 (665 download)

Book Synopsis Brain Neurotrauma by : Firas H. Kobeissy

Download or read book Brain Neurotrauma written by Firas H. Kobeissy and published by CRC Press. This book was released on 2015-02-25 with total page 718 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the contribution from more than one hundred CNS neurotrauma experts, this book provides a comprehensive and up-to-date account on the latest developments in the area of neurotrauma including biomarker studies, experimental models, diagnostic methods, and neurotherapeutic intervention strategies in brain injury research. It discusses neurotrauma mechanisms, biomarker discovery, and neurocognitive and neurobehavioral deficits. Also included are medical interventions and recent neurotherapeutics used in the area of brain injury that have been translated to the area of rehabilitation research. In addition, a section is devoted to models of milder CNS injury, including sports injuries.

Astrocytes

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Author : Barbara Di Benedetto
Publisher : Humana
ISBN 13 : 9781493990672
Total Pages : 0 pages
Book Rating : 4.9/5 (96 download)

Book Synopsis Astrocytes by : Barbara Di Benedetto

Download or read book Astrocytes written by Barbara Di Benedetto and published by Humana. This book was released on 2019-01-08 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This detailed volume gathers together a broad variety of methods essential to the investigation of the biology of astrocytes and their multifaceted roles in both healthy and diseased brains. Beginning with some overviews of the subject, the book continues by covering techniques for the isolation of astrocytes from animal models, the investigation of astrocyte morphology and function, as well as for understanding astrocyte pathologies in the central nervous system. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Astrocytes: Methods and Protocols serves as an ideal guide for both experienced and beginner scientists working toward unraveling the novel, fascinating roles of these versatile cells.

Enteric Glia

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Author : Brian D. Gulbransen
Publisher : Biota Publishing
ISBN 13 : 1615046615
Total Pages : 72 pages
Book Rating : 4.6/5 (15 download)

Book Synopsis Enteric Glia by : Brian D. Gulbransen

Download or read book Enteric Glia written by Brian D. Gulbransen and published by Biota Publishing. This book was released on 2014-07-01 with total page 72 pages. Available in PDF, EPUB and Kindle. Book excerpt: The enteric nervous system (ENS) is a complex neural network embedded in the gut wall that orchestrates the reflex behaviors of the intestine. The ENS is often referred to as the “little brain” in the gut because the ENS is more similar in size, complexity and autonomy to the central nervous system (CNS) than other components of the autonomic nervous system. Like the brain, the ENS is composed of neurons that are surrounded by glial cells. Enteric glia are a unique type of peripheral glia that are similar to astrocytes of the CNS. Yet enteric glial cells also differ from astrocytes in many important ways. The roles of enteric glial cell populations in the gut are beginning to come to light and recent evidence implicates enteric glia in almost every aspect of gastrointestinal physiology and pathophysiology. However, elucidating the exact mechanisms by which enteric glia influence gastrointestinal physiology and identifying how those roles are altered during gastrointestinal pathophysiology remain areas of intense research. The purpose of this e-book is to provide an introduction to enteric glial cells and to act as a resource for ongoing studies on this fascinating population of glia. Table of Contents: Introduction / A Historical Perspective on Enteric Glia / Enteric Glia: The Astroglia of the Gut / Molecular Composition of Enteric Glia / Development of Enteric Glia / Functional Roles of Enteric Glia / Enteric Glia and Disease Processes in the Gut / Concluding Remarks / References / Author Biography

The Biochemical Pathology of Astrocytes

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Author : Michael D. Norenberg
Publisher :
ISBN 13 :
Total Pages : 680 pages
Book Rating : 4.3/5 (91 download)

Book Synopsis The Biochemical Pathology of Astrocytes by : Michael D. Norenberg

Download or read book The Biochemical Pathology of Astrocytes written by Michael D. Norenberg and published by . This book was released on 1988 with total page 680 pages. Available in PDF, EPUB and Kindle. Book excerpt: Astrocytes have been associated with a number of neuropsychiatric disorders. This edited volume reviews the state of knowledge on the role of astrocytes in such neuropsychiatric conditions as anoxia/ischemia, edema, epilepsy, demyelinative disorders, degenerative diseases, toxic-metabolic encephalopathies, psychiatric abnormalities, and the role of reactive astrocytes in various pathologic states.

Astrocytes

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Author : Eliana Scemes
Publisher : CRC Press
ISBN 13 : 1439825858
Total Pages : 425 pages
Book Rating : 4.4/5 (398 download)

Book Synopsis Astrocytes by : Eliana Scemes

Download or read book Astrocytes written by Eliana Scemes and published by CRC Press. This book was released on 2016-04-19 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt: Astrocytes play diverse roles in central nervous system (CNS) function and dysfunction, and the connections that the astrocyte makes with other cells of the brain are essential for a variety of important neural tasks. Bringing together contributions from international experts at the top of their field, Astrocytes: Wiring the Brain emphasizes cellul

New Developments in Astrocytes Research

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Author :
Publisher :
ISBN 13 : 9781634855846
Total Pages : pages
Book Rating : 4.8/5 (558 download)

Book Synopsis New Developments in Astrocytes Research by :

Download or read book New Developments in Astrocytes Research written by and published by . This book was released on 2016-09-01 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Astrocytes and Epilepsy

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Author : Jacqueline A. Hubbard
Publisher : Academic Press
ISBN 13 : 0128026243
Total Pages : 395 pages
Book Rating : 4.1/5 (28 download)

Book Synopsis Astrocytes and Epilepsy by : Jacqueline A. Hubbard

Download or read book Astrocytes and Epilepsy written by Jacqueline A. Hubbard and published by Academic Press. This book was released on 2016-07-05 with total page 395 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epilepsy is a devastating group of neurological disorders characterized by periodic and unpredictable seizure activity in the brain. There is a critical need for new drugs and approaches given than at least one-third of all epilepsy patients are not made free of seizures by existing medications and become "medically refractory". Much of epilepsy research has focused on neuronal therapeutic targets, but current antiepileptic drugs often cause severe cognitive, developmental, and behavioral side effects. Recent findings indicate a critical contribution of astrocytes, star-shaped glial cells in the brain, to neuronal and network excitability and seizure activity. Furthermore, many important cellular and molecular changes occur in astrocytes in epileptic tissue in both humans and animal models of epilepsy. The goal of Astrocytes and Epilepsy is to comprehensively review exciting findings linking changes in astrocytes to functional changes responsible for epilepsy for the first time in book format. These insights into astrocyte contribution to seizure susceptibility indicate that astrocytes may represent an important new therapeutic target in the control of epilepsy. Astrocytes and Epilepsy includes background explanatory text on astrocyte morphology and physiology, epilepsy models and syndromes, and evidence from both human tissue studies and animal models linking functional changes in astrocytes to epilepsy. Beautifully labelled diagrams are presented and relevant figures from the literature are reproduced to elucidate key findings and concepts in this rapidly emerging field. Astrocytes and Epilepsy is written for neuroscientists, epilepsy researchers, astrocyte investigators as well as neurologists and other specialists caring for patients with epilepsy. Presents the first comprehensive book to synthesize historical and recent research on astrocytes and epilepsy into one coherent volume Provides a great resource on the field of astrocyte biology and astrocyte-neuron interactions Details potential therapeutic targets, including chapters on gap junctions, water and potassium channels, glutamate and adenosine metabolism, and inflammation

Astrocytes

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Author : Eliana Scemes
Publisher : CRC Press
ISBN 13 : 143982584X
Total Pages : 437 pages
Book Rating : 4.4/5 (398 download)

Book Synopsis Astrocytes by : Eliana Scemes

Download or read book Astrocytes written by Eliana Scemes and published by CRC Press. This book was released on 2011-11-28 with total page 437 pages. Available in PDF, EPUB and Kindle. Book excerpt: Astrocytes play diverse roles in central nervous system (CNS) function and dysfunction, and the connections that the astrocyte makes with other cells of the brain are essential for a variety of important neural tasks. Bringing together contributions from international experts at the top of their field, Astrocytes: Wiring the Brain emphasizes cellular connections and surveys the most current findings on astrocyte activity. The first section of the book identifies major astrocyte biomarkers and describes how they define the different connectivity domains. Next, the book examines the role of these connections. It explains how their function can be manipulated under physiological conditions and how dysfunction of the connectivity leads to aberrant brain performance. The final section explores the alterations of glia that have been observed in specific diseases of the brain. These include epilepsy, autoimmune encephalitis, Alzheimer’s disease, autism, and major depression. The book identifies key mechanisms responsible for these alterations. An important and emerging field, astrocytes and their functions are critical to neuroscientists and neurologists, both in academia and in industry, particularly in the search for and development of new drugs to combat a variety of diseases affecting the CNS. As research continues to grow in this area, this volume will spur heightened advances and understanding into the effects of these neural cells on a range of pathologies.

Cell Biology and Pathology of Myelin

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Author : Bernhard H.J. Juurlink
Publisher : Springer Science & Business Media
ISBN 13 : 1461559499
Total Pages : 392 pages
Book Rating : 4.4/5 (615 download)

Book Synopsis Cell Biology and Pathology of Myelin by : Bernhard H.J. Juurlink

Download or read book Cell Biology and Pathology of Myelin written by Bernhard H.J. Juurlink and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of the Fourth International Altschul Symposium held at Saskatoon, Saskatchewan, Canada, June 27-29, 1996

Glial Neurobiology

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Author : Alexei Verkhratsky
Publisher : John Wiley & Sons
ISBN 13 : 9780470513071
Total Pages : 230 pages
Book Rating : 4.5/5 (13 download)

Book Synopsis Glial Neurobiology by : Alexei Verkhratsky

Download or read book Glial Neurobiology written by Alexei Verkhratsky and published by John Wiley & Sons. This book was released on 2007-08-20 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This volume is a very valuable and much needed contribution." –Quarterly Review of Biology AT LAST - A comprehensive, accessible textbook on glial neurobiology! Glial cells are the most numerous cells in the human brain but for many years have attracted little scientific attention. Neurophysiologists concentrated their research efforts instead, on neurones and neuronal networks because it was thought that they were the key elements responsible for higher brain function. Recent advances, however, indicate this isn’t exactly the case. Not only are astroglial cells the stem elements from which neurones are born, but they also control the development, functional activity and death of neuronal circuits. These ground-breaking developments have revolutionized our understanding of the human brain and the complex interrelationship of glial and neuronal networks in health and disease. Features of this book: an accessible introduction to glial neurobiology including an overview of glial cell function and its active role in neural processes, brain function and nervous system pathology an exploration of all the major types of glial cells including: the astrocytes, oligodendrocytes and microglia of the ACNS and Schwann cells of the peripheral nervous system; the book also presents a broad overview of glial receptors and ion channels an investigation into the role of glial cells in various types of brain diseases including stroke, neurodegenerative diseases such as Alzheimer's, Parkinson's and Alexander's disease, brain oedema, multiple sclerosis and many more a wealth of illustrations, including unique images from the authors' own libraries of images, describing the main features of glial cells Written by two leading experts in the field, Glial Neurobiology provides a concise, authoritative introduction to glial physiology and pathology for undergraduate/postgraduate neuroscience, biomedical, medical, pharmacy, pharmacology, and neurology, neurosurgery and physiology students. It is also an invaluable resource for researchers in neuroscience, physiology, pharmacology and pharmaceutics.

The Role of Microglial Cells and Astrocytes in Pathology

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Author : Jean Merrill
Publisher : S Karger Ag
ISBN 13 : 9783805560863
Total Pages : 123 pages
Book Rating : 4.5/5 (68 download)

Book Synopsis The Role of Microglial Cells and Astrocytes in Pathology by : Jean Merrill

Download or read book The Role of Microglial Cells and Astrocytes in Pathology written by Jean Merrill and published by S Karger Ag. This book was released on 1994 with total page 123 pages. Available in PDF, EPUB and Kindle. Book excerpt: