Associative Ion Molecule Reactions And Ion Trapping With A Triple Quadrupole Mass Spectrometer

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Quadrupole Ion Trap Mass Spectrometry

Author : Raymond E. March
Publisher : Wiley-Interscience
ISBN 13 : 9780471717980
Total Pages : 416 pages
Book Rating : 4.7/5 (179 download)

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Book Synopsis Quadrupole Ion Trap Mass Spectrometry by : Raymond E. March

Download or read book Quadrupole Ion Trap Mass Spectrometry written by Raymond E. March and published by Wiley-Interscience. This book was released on 2005-09-12 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: A definitive reference, completely updated Published in 1989, the First Edition of this book, originally entitled Quadrupole Storage Mass Spectrometry, quickly became the definitive reference in analytical laboratories worldwide. Revised to reflect scientific and technological advances and new applications in the field, the Second Edition includes new chapters covering: * New ion trap instruments of high sensitivity * Peptide analysis by liquid chromatography/ion trap tandem mass spectrometry * Analytical aspects of ion trap mass spectrometry combined with gas chromatography * Simulation of ion trajectories in the ion trap One additional chapter discusses the Rosetta mission, a "comet chaser" that was sent on a ten-year journey in 2004 to study the comet Churyumov-Gerasimenko using, among other instruments, a GC/MS system incorporating a specially designed ion trap mass spectrometer. This comprehensive reference also includes discussions of the history of the quadrupole ion trap, the theory of quadrupole mass spectrometry, the dynamics of ion-trapping chemistry in the quadrupole ion trap, the cylindrical ion trap, miniature traps, and linear ion traps. Complete with conclusions and references, this primer effectively encapsulates the body of knowledge on quadrupole ion trap mass spectrometry. With its concise descriptions of the theory of ion motion and the principles of operation, Quadrupole Ion Trap Mass Spectrometry, Second Edition is ideal for new users of quadrupole devices, as well as for scientists, researchers, and graduate and post-doctoral students working in analytical laboratories.

Proteome Research: Mass Spectrometry

Author : Peter James
Publisher : Springer
ISBN 13 : 9783540672555
Total Pages : 306 pages
Book Rating : 4.6/5 (725 download)

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Book Synopsis Proteome Research: Mass Spectrometry by : Peter James

Download or read book Proteome Research: Mass Spectrometry written by Peter James and published by Springer. This book was released on 2000-10-26 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent advances in large scale DNA sequencing technology have made it possible to sequence the entire genome of an organism. Attention is now turning to the analysis of the product of the genome, the proteome, which is the set of proteins being expressed by a cell. Mass spectrometry is the method of choice for the rapid large-scale identification of these proteomes and their modifications. This is the first book to extensively cover the applications of mass spectrometry to proteome research.

Proceedings of the ... ASMS Conference on Mass Spectrometry and Allied Topics

Author :
Publisher :
ISBN 13 :
Total Pages : 2284 pages
Book Rating : 4.:/5 (43 download)

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Book Synopsis Proceedings of the ... ASMS Conference on Mass Spectrometry and Allied Topics by :

Download or read book Proceedings of the ... ASMS Conference on Mass Spectrometry and Allied Topics written by and published by . This book was released on 1992 with total page 2284 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Principles of Forensic Toxicology

Author : Barry Levine
Publisher : Amer. Assoc. for Clinical Chemistry
ISBN 13 : 9781890883874
Total Pages : 406 pages
Book Rating : 4.8/5 (838 download)

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Book Synopsis Principles of Forensic Toxicology by : Barry Levine

Download or read book Principles of Forensic Toxicology written by Barry Levine and published by Amer. Assoc. for Clinical Chemistry. This book was released on 2003 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Mass Spectrometry for the Clinical Laboratory

Author : Hari Nair
Publisher : Academic Press
ISBN 13 : 0128009926
Total Pages : 306 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Mass Spectrometry for the Clinical Laboratory by : Hari Nair

Download or read book Mass Spectrometry for the Clinical Laboratory written by Hari Nair and published by Academic Press. This book was released on 2016-11-02 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mass Spectrometry for the Clinical Laboratory is an accessible guide to mass spectrometry and the development, validation, and implementation of the most common assays seen in clinical labs. It provides readers with practical examples for assay development, and experimental design for validation to meet CLIA requirements, appropriate interference testing, measuring, validation of ion suppression/matrix effects, and quality control. These tools offer guidance on what type of instrumentation is optimal for each assay, what options are available, and the pros and cons of each. Readers will find a full set of tools that are either directly related to the assay they want to adopt or for an analogous assay they could use as an example. Written by expert users of the most common assays found in a clinical laboratory (clinical chemists, toxicologists, and clinical pathologists practicing mass spectrometry), the book lays out how experts in the field have chosen their mass spectrometers, purchased, installed, validated, and brought them on line for routine testing. The early chapters of the book covers what the practitioners have learned from years of experience, the challenges they have faced, and their recommendations on how to build and validate assays to avoid problems. These chapters also include recommendations for maintaining continuity of quality in testing. The later parts of the book focuses on specific types of assays (therapeutic drugs, Vitamin D, hormones, etc.). Each chapter in this section has been written by an expert practitioner of an assay that is currently running in his or her clinical lab. Provides readers with the keys to choosing, installing, and validating a mass spectrometry platform Offers tools to evaluate, validate, and troubleshoot the most common assays seen in clinical pathology labs Explains validation, ion suppression, interference testing, and quality control design to the detail that is required for implementation in the lab

Ion/Molecule Attachment Reactions: Mass Spectrometry

Author : Toshihiro Fujii
Publisher : Springer
ISBN 13 : 1489975888
Total Pages : 350 pages
Book Rating : 4.4/5 (899 download)

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Book Synopsis Ion/Molecule Attachment Reactions: Mass Spectrometry by : Toshihiro Fujii

Download or read book Ion/Molecule Attachment Reactions: Mass Spectrometry written by Toshihiro Fujii and published by Springer. This book was released on 2015-08-03 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores the mechanism of alkali-metal ion/molecule association reaction, surveys the instrumental basis to study its kinetic, and describes the instrumentation to the measurement of alkali-metal ion affinities. The applications of the ion complexation mechanism in the condensed phase in reaction to direct analysis MS are also covered. Other topics include mechanism and reaction rate, experimental and theoretical ion affinities, applications of ion attachment reactions (IAR) to mass spectrometry such as alkali ion CIMS, ion attachment MS and cationization mass spectrometry of ESI, FAB, FD, LD, MALDI and SIMS and topics of IAR-based direct analysis mass spectrometry.

Quadrupole Ion Trap Mass Spectrometry

Author : Raymond E. March
Publisher : John Wiley & Sons
ISBN 13 : 0471717975
Total Pages : 389 pages
Book Rating : 4.4/5 (717 download)

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Book Synopsis Quadrupole Ion Trap Mass Spectrometry by : Raymond E. March

Download or read book Quadrupole Ion Trap Mass Spectrometry written by Raymond E. March and published by John Wiley & Sons. This book was released on 2005-09-15 with total page 389 pages. Available in PDF, EPUB and Kindle. Book excerpt: A definitive reference, completely updated Published in 1989, the First Edition of this book, originally entitled Quadrupole Storage Mass Spectrometry, quickly became the definitive reference in analytical laboratories worldwide. Revised to reflect scientific and technological advances and new applications in the field, the Second Edition includes new chapters covering: * New ion trap instruments of high sensitivity * Peptide analysis by liquid chromatography/ion trap tandem mass spectrometry * Analytical aspects of ion trap mass spectrometry combined with gas chromatography * Simulation of ion trajectories in the ion trap One additional chapter discusses the Rosetta mission, a "comet chaser" that was sent on a ten-year journey in 2004 to study the comet Churyumov-Gerasimenko using, among other instruments, a GC/MS system incorporating a specially designed ion trap mass spectrometer. This comprehensive reference also includes discussions of the history of the quadrupole ion trap, the theory of quadrupole mass spectrometry, the dynamics of ion-trapping chemistry in the quadrupole ion trap, the cylindrical ion trap, miniature traps, and linear ion traps. Complete with conclusions and references, this primer effectively encapsulates the body of knowledge on quadrupole ion trap mass spectrometry. With its concise descriptions of the theory of ion motion and the principles of operation, Quadrupole Ion Trap Mass Spectrometry, Second Edition is ideal for new users of quadrupole devices, as well as for scientists, researchers, and graduate and post-doctoral students working in analytical laboratories.

Analyzing Biomolecular Interactions by Mass Spectrometry

Author : Jeroen Kool
Publisher : John Wiley & Sons
ISBN 13 : 3527334645
Total Pages : 402 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Analyzing Biomolecular Interactions by Mass Spectrometry by : Jeroen Kool

Download or read book Analyzing Biomolecular Interactions by Mass Spectrometry written by Jeroen Kool and published by John Wiley & Sons. This book was released on 2015-05-04 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph reviews all relevant technologies based on mass spectrometry that are used to study or screen biological interactions in general. Arranged in three parts, the text begins by reviewing techniques nowadays almost considered classical, such as affinity chromatography and ultrafiltration, as well as the latest techniques. The second part focusses on all MS-based methods for the study of interactions of proteins with all classes of biomolecules. Besides pull down-based approaches, this section also emphasizes the use of ion mobility MS, capture-compound approaches, chemical proteomics and interactomics. The third and final part discusses other important technologies frequently employed in interaction studies, such as biosensors and microarrays. For pharmaceutical, analytical, protein, environmental and biochemists, as well as those working in pharmaceutical and analytical laboratories.

Practical Aspects of Ion Trap Mass Spectrometry

Author : Raymond E. March
Publisher : CRC Press
ISBN 13 : 9780849382512
Total Pages : 542 pages
Book Rating : 4.3/5 (825 download)

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Book Synopsis Practical Aspects of Ion Trap Mass Spectrometry by : Raymond E. March

Download or read book Practical Aspects of Ion Trap Mass Spectrometry written by Raymond E. March and published by CRC Press. This book was released on 1995-10-23 with total page 542 pages. Available in PDF, EPUB and Kindle. Book excerpt: By delivering concentrated information in three different volumes, the editors of the Practical Aspects of Ion Trap Mass Spectrometry mini-series present in-depth reviews on mainstream developments in each active and popular area. Contributing authors provide concise reports illustrating successful approaches to difficult analytical problems across the basic scientific disciplines. Volume three, Chemical, Environmental, and Biomedical Applications, presents a coherent picture of research and applications in the ion trapping field. It examines tandem mass spectrometry, the principal mode of ion trap operation, where one stage of mass selectivity follows another in the same region of space. This volume discusses the fundamentals of ion trap theory, design, and operation; practical ion trap technology; applications involving small molecules; and the environmental and biomedical applications.

Quadrupole Mass Spectrometry and Its Applications

Author : Peter H. Dawson
Publisher : Elsevier
ISBN 13 : 1483165043
Total Pages : 372 pages
Book Rating : 4.4/5 (831 download)

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Book Synopsis Quadrupole Mass Spectrometry and Its Applications by : Peter H. Dawson

Download or read book Quadrupole Mass Spectrometry and Its Applications written by Peter H. Dawson and published by Elsevier. This book was released on 2013-10-22 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: Quadrupole Mass Spectrometry and Its Applications provides a comprehensive discussion of quadrupoles and their applications. It proceeds from a general explanation of the action of radiofrequency quadrupole fields to the description of their utilization in mass analyzers—such as the quadrupole mass filter, the monopole, the three-dimensional quadrupole ion trap, and various time-of-flight spectrometers—and finally to the characteristic applications of quadrupoles. A multi-author format has been adopted to provide broader-than-usual viewpoint in the book. The book begins by explaining the principles of operation of quadrupole devices. These include ion trajectories and computer simulations of performance; analytical theory; numerical methods of calculation of performance, including the recently developed application of phase-space dynamics; and fringing fields and other field imperfections. Subsequent chapters provide design and performance evaluations of the mass filter, the monopole, ion traps, and time-of-flight instruments; and describe areas of application where quadrupole devices have made the greatest impact because of their particular advantages and disadvantages.

Modern Instrumental Analysis

Author : Satinder Ahuja
Publisher : Elsevier
ISBN 13 : 0080467229
Total Pages : 897 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Modern Instrumental Analysis by : Satinder Ahuja

Download or read book Modern Instrumental Analysis written by Satinder Ahuja and published by Elsevier. This book was released on 2006-10-17 with total page 897 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern Instrumental Analysis covers the fundamentals of instrumentation and provides a thorough review of the applications of this technique in the laboratory. It will serve as an educational tool as well as a first reference book for the practicing instrumental analyst. The text covers five major sections:1. Overview, Sampling, Evaluation of Physical Properties, and Thermal Analysis2. Spectroscopic Methods 3. Chromatographic Methods 4. Electrophoretic and Electrochemical Methods 5. Combination Methods, Unique Detectors, and Problem Solving Each section has a group of chapters covering important aspects of the titled subject, and each chapter includes applications that illustrate the use of the methods. The chapters also include an appropriate set of review questions.* Covers the fundamentals of instrumentation as well as key applications * Each chapter includes review questions that reinforce concepts * Serves as a quick reference and comprehensive guidebook for practitioners and students alike

Mass Spectrometry/mass Spectrometry

Author : Kenneth L. Busch
Publisher :
ISBN 13 :
Total Pages : 360 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis Mass Spectrometry/mass Spectrometry by : Kenneth L. Busch

Download or read book Mass Spectrometry/mass Spectrometry written by Kenneth L. Busch and published by . This book was released on 1988 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book of Abstracts

Author :
Publisher :
ISBN 13 :
Total Pages : 684 pages
Book Rating : 4.0/5 ( download)

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Book Synopsis Book of Abstracts by :

Download or read book Book of Abstracts written by and published by . This book was released on 1992 with total page 684 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Mass Spectrometry

Author : Jürgen H Gross
Publisher : Springer Science & Business Media
ISBN 13 : 3540407391
Total Pages : 534 pages
Book Rating : 4.5/5 (44 download)

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Book Synopsis Mass Spectrometry by : Jürgen H Gross

Download or read book Mass Spectrometry written by Jürgen H Gross and published by Springer Science & Business Media. This book was released on 2006-04-05 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mass Spectrometry is an ideal textbook for students and professionals as well as newcomers to the field. Starting from the very first principles of gas-phase ion chemistry and isotopic properties, the textbook takes the reader through the design of mass analyzers and ionization methods all the way to mass spectral interpretation and coupling techniques. Step-by-step, the reader learns how mass spectrometry works and what it can do. The book comprises a balanced mixture of practice-oriented information and theoretical background. It features a clear layout and a wealth of high-quality figures. Exercises and solutions are located on the Springer Global Web.

Spectroscopy and Modeling of Biomolecular Building Blocks

Author : Jean-Pierre Schermann
Publisher : Elsevier
ISBN 13 : 0080558224
Total Pages : 499 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Spectroscopy and Modeling of Biomolecular Building Blocks by : Jean-Pierre Schermann

Download or read book Spectroscopy and Modeling of Biomolecular Building Blocks written by Jean-Pierre Schermann and published by Elsevier. This book was released on 2007-10-16 with total page 499 pages. Available in PDF, EPUB and Kindle. Book excerpt: Spectroscopy and Modeling of Biomolecular Building Blocks presents an overview of recent advances in the intertwining of the following research fields: photon and electron spectroscopy, quantum chemistry, modelling and mass-spectrometry. The coupling of these disciplines offers a new point of view to the understanding of isolated elementary building blocks of biomolecules and their assemblies. It allows the unambiguous separation between intrinsic properties of biomolecular systems and those induced by the presence of their environment. The first chapters provide background in modelling (I), frequency-resolved spectroscopy using microwave, infrared and UV photons, time-resolved spectroscopy in the femtosecond domain and energy-resolved electron spectroscopy (II) and production of gas-phase neutral and ionic biomolecular species, mass-spectrometry, ion mobility and BIRD techniques (III). Chapter IV is devoted to case studies of gas-phase experimental investigations coupled to quantum or classical calculations. The topics are structural studies of nucleobases and oligonucleotides, peptides and proteins, sugars; neuromolecules; non-covalent complexes; chiral systems, interactions of low-energy electrons with biomolecules in the radiation chemistry context and very large gas-phase biomolecular systems. The fifth chapter concerns the link between gas-phase and liquid-phase. Different treatments of solvation are illustrated through examples pointing out the influence of progressive addition of water molecules upon properties of nucleobases, peptides, sugars and neuromolecules. - Offer a new perspective to the understanding of isolated elementary building blocks of bio molecules - Includes case studies of experimental investigations coupled to quantum or classical calculations

Principles and Applications of Clinical Mass Spectrometry

Author : Nader Rifai
Publisher : Elsevier
ISBN 13 : 0128160640
Total Pages : 218 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Principles and Applications of Clinical Mass Spectrometry by : Nader Rifai

Download or read book Principles and Applications of Clinical Mass Spectrometry written by Nader Rifai and published by Elsevier. This book was released on 2018-06-26 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles and Applications of Clinical Mass Spectrometry: Small Molecules, Peptides, and Pathogens is a concise resource for quick implementation of mass spectrometry methods in clinical laboratory work. Focusing on the practical use of these techniques, the first half of the book covers principles of chromatographic separations, principles and types of mass spectrometers, and sample preparation for analysis; the second half outlines the main applications of this technology within clinical laboratory settings, including determination of small molecules and peptides, as well as pathogen identification. A thorough yet succinct guide to using mass spectrometry technology in the clinical laboratory, Principles and Applications of Clinical Mass Spectrometry: Small Molecules, Peptides, and Pathogens is an essential resource for chemists, pharmaceutical and biotech researchers, certain government agencies, and standardization groups. - Provides concrete examples of the main applications of mass spectrometry technology - Describes current capabilities of the LC- and MS-based analytical methods - Details methods for successful analytical work in the field

Chemical Ionization Mass Spectrometry

Author : Alex. G. Harrison
Publisher : Taylor & Francis
ISBN 13 : 1351461540
Total Pages : 221 pages
Book Rating : 4.3/5 (514 download)

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Book Synopsis Chemical Ionization Mass Spectrometry by : Alex. G. Harrison

Download or read book Chemical Ionization Mass Spectrometry written by Alex. G. Harrison and published by Taylor & Francis. This book was released on 2018-05-11 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt: The only comprehensive guide to CIMS applications in structural elucidation and analytical studies Chemical Ionization Mass Spectrometry, 2nd Edition, provides a comprehensive, up-to-date review of CIMS applications in structural elucidation and quantitative analytical studies. For the benefit of readers without a background in gaseous ion chemistry, a thorough review is presented in Chapter 2. Other chapters discuss such topics as reagent ion systems within the context of the thermochemistry and kinetics of the ionization process, including reactions and the type of information obtained; isotopic exchange reactions; stereochemical effects in chemical ionization; and reactive ion/molecule collisions in quadrupole cells. Chemical ionization mass spectra of 13 classes of compounds are discussed in detail to illustrate the influence of different functional groups on the spectra observed. Chemical Ionization Mass Spectrometry, 2nd Edition will be a valuable reference for anyone interested in mass spectrometry and gaseous ion chemistry in general.