Read Books Online and Download eBooks, EPub, PDF, Mobi, Kindle, Text Full Free.
Download Aspartic Proteinases And Their Inhibitors full books in PDF, epub, and Kindle. Read online Aspartic Proteinases And Their Inhibitors ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Author : Vladimír Kostka
Publisher : Walter de Gruyter GmbH & Co KG
ISBN 13 : 3111649784
Total Pages : 640 pages
Book Rating : 4.1/5 (116 download)
Download or read book Aspartic Proteinases and Their Inhibitors written by Vladimír Kostka and published by Walter de Gruyter GmbH & Co KG. This book was released on 2016-01-29 with total page 640 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Michael N.G. James
Publisher : Springer Science & Business Media
ISBN 13 : 1461553733
Total Pages : 484 pages
Book Rating : 4.4/5 (615 download)
Download or read book Aspartic Proteinases written by Michael N.G. James and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: The VIIth International Conference on Aspartic Proteinases was held in Banff, Alberta, Canada, from October 22 to 27, 1996. The venue was the Banff Centre in the Canadian Rockies, a setting well known worldwide for the scenic beauty and mountain grandeur. It was perhaps presumptuous of the organizers to call this the seventh Aspartic Proteinase Conference but it was felt that the meeting in 1982, organized by Tom Blundell and John Kay, was of an international stature and covered topics sufficiently broad to constitute a conference. Thus, there is a discontinuity in that the Gifu Conference organized by Prof. Kenji Takahashi was the fifth International Conference on Aspartic Proteinases. Officially, there has not been a sixth Conference and if there is confusion, it is the result of my desire to recognize the importance of the London meeting. Banffhosted 106 scientists from 14 different countries. There were 26 invited speak ers among the 44 oral presentations of the 7 main sessions. In addition, there were 53 con tributed poster presentations that spanned the whole range of interest in aspartic proteinases.
Author : Arun K. Ghosh
Publisher : John Wiley & Sons
ISBN 13 : 3527641629
Total Pages : 616 pages
Book Rating : 4.5/5 (276 download)
Download or read book Aspartic Acid Proteases as Therapeutic Targets written by Arun K. Ghosh and published by John Wiley & Sons. This book was released on 2011-08-04 with total page 616 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this ground-breaking practical reference, the family of aspartic acid proteases is described from a drug developer's perspective. The first part provides a general introduction to the family of aspartic acid proteases, their physiological functions, molecular structure and inhibition. Parts two to five present various case studies of successful protease inhibitor drug design and development, as well as current and potential uses of such inhibitors in pharmaceutical medicine, covering the major therapeutic targets HIV-1 protease, renin, beta-secretase, gamma-secretase,plasmepsins and fungal proteases. A ready reference aimed primarily at professionals in the pharmaceutical industry, as well as for anyone studying proteases and their function.
Author : Ben M. Dunn
Publisher : Springer Science & Business Media
ISBN 13 : 1468460129
Total Pages : 561 pages
Book Rating : 4.4/5 (684 download)
Download or read book Structure and Function of the Aspartic Proteinases written by Ben M. Dunn and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 561 pages. Available in PDF, EPUB and Kindle. Book excerpt: In September, 1990, a group of 160 scientists from 19 countries and 21 of the United States met at the Red Lion Inn in Rohnert Park, Sonoma County, California. The purpose of this meeting was to share new information from recent research on the Aspartic Proteinases. This book is a compilation of the information transferred in that forum. The Aspartic Proteinases include all those enzymes from the "fourth" class of proteolytic enzymes, the first three being the Serine, Cysteine and Metalloproteinases. Of course, all the scientists in attendance at the Sonoma Aspartic Proteinase Conference would agree that our current level of understanding of the structure and function of the Aspartic Proteinase class of enzymes is clearly first class. The reasons for this require a bit of historical perspective. The group of scientists who are engaged in study of this family of enzymes first met as a separate entity in 1976, in Norman, Oklahoma, at a meeting organized by Jordan Tang of the Oklahoma Medical Research Foundation. This was an exciting time, as the first crystal structures of some of these enzymes were described by Blundell, James and Davies. During that conference, the relationship between the two halves of the mammalian and fungal enzymes was recognized and this has provided a structural foundation for analysis of the retroviral enzymes, which came later. A book was published by Plenum Press documenting l this conference, and the current book is an update to that important work.
Author :
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (246 download)
Download or read book Aspartic Proteinases and Their Inhibitors written by and published by . This book was released on 1985 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher : Academic Press
ISBN 13 : 0080865968
Total Pages : 471 pages
Book Rating : 4.0/5 (88 download)
Download or read book Mechanisms of Catalysis written by and published by Academic Press. This book was released on 1991-01-28 with total page 471 pages. Available in PDF, EPUB and Kindle. Book excerpt: The remarkable expansion of information leading to a deeper understanding of enzymes on the molecular level necessitated the development of this volume which not only introduces new topics to The Enzymes series but presents new information on some covered in Volume I and II of this edition.
Author : Vladimír Kostka
Publisher : de Gruyter
ISBN 13 : 9783111266329
Total Pages : 0 pages
Book Rating : 4.2/5 (663 download)
Download or read book Aspartic Proteinases and Their Inhibitors written by Vladimír Kostka and published by de Gruyter. This book was released on 1985-04 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Martin Fusek
Publisher : CRC Press
ISBN 13 : 0429536003
Total Pages : 324 pages
Book Rating : 4.4/5 (295 download)
Download or read book Aspartic Proteinases Physiology and Pathology written by Martin Fusek and published by CRC Press. This book was released on 2019-10-10 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: Published in 1995: Aspartic Proteinases: Physiology and Pathology focuses on the advantages and limitations of the use of proteinases and their inhibitors in human pathology. A virus-specific aspartic proteinase enzyme is required for the maturation of a virus. If the enzyme can be eliminated, so can the maturation of the virus. This book reviews the wealth of recently published information sparked by the renewed interest in these enzymes.
Author : Kenji Takahashi
Publisher : Springer Science & Business Media
ISBN 13 : 1461518717
Total Pages : 614 pages
Book Rating : 4.4/5 (615 download)
Download or read book Aspartic Proteinases written by Kenji Takahashi and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 614 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 5th International Conference on Aspartic Proteinases was held on September 19 through 24, 1993, at Naito Museum of Pharmaceutical Science and Industry, Kawashima cho, Gifu Prefecture, Japan, about 15 miles northwest of Nagoya City. About 100 scientists attended the conference, including 52 from 14 countries outside Japan, and 32 papers were presented by invited speakers, and 58 papers as posters. The purpose of this conference was to present and discuss new information on the structure, function, and biology, and related topics, including biomedical implications, of aspartic proteinases, and this book is a collec tion of nearly all the papers presented at the meeting. Aspartic proteinases belong to one of the four major classes of proteinases, the others being serine, cysteine, and metalloproteinases, and are so called since they have two catalytic aspartic acid residues in common in their active sites. Most of them are optimally active at acidic pH, hence the long-used name "acid proteinases," which, indeed, was the major title of the first conference of this series. However, some of them are active at around neutral pH, indicating their physiological roles in a wider range of pH than hitherto considered.
Author : Yehudith Birk
Publisher : Springer Science & Business Media
ISBN 13 : 9783540001188
Total Pages : 192 pages
Book Rating : 4.0/5 (11 download)
Download or read book Plant Protease Inhibitors written by Yehudith Birk and published by Springer Science & Business Media. This book was released on 2003-04-08 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plant protease inhibitors are diverse in number & specificity towards various proteolytic enzymes.
Author : Nobuhiko Katunuma
Publisher : IOS Press
ISBN 13 : 9789051992922
Total Pages : 224 pages
Book Rating : 4.9/5 (929 download)
Download or read book Medical Aspects of Proteases and Protease Inhibitors written by Nobuhiko Katunuma and published by IOS Press. This book was released on 1997 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: The work presents articles on proteases and their inhibitors as mediators of biological functions. Topics addressed: cathepsin B and L; MHC and peptide interaction; procathepsin L; cysteine proteinases; selective neuronal cell death; HIV and influenza virus; tumor invasion; gingivitis; bacterial infection. Readers: professionals in the area of molecular medicine, biochemists, molecular biologists, clinical pharmacologists, pharmaceutical companies.
Author : Mercedes Diaz-Mendoza
Publisher : Frontiers Media SA
ISBN 13 : 2889633993
Total Pages : 157 pages
Book Rating : 4.8/5 (896 download)
Download or read book Plant Proteases written by Mercedes Diaz-Mendoza and published by Frontiers Media SA. This book was released on 2020-01-24 with total page 157 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plant proteases are involved in most aspects of plant physiology and development, playing key roles in the generation of signaling molecules and as regulators of essential cellular processes such as cell division and metabolism. They take part in important pathways like protein turnover by the degradation of misfolded proteins and the ubiquitin-proteasome pathway, and they are responsible for post-translational modifications of proteins by proteolysis at highly specific sites. Proteases are also implicated in a great variety of environmentally controlled processes, including mobilization of storage proteins during seed germination, development of seedlings, senescence, programmed cell death and defense mechanisms against pests and pathogens. However, in spite of their importance, little is known about the functions and mode of actions of specific plant proteases. This Research Topic collects contributions covering diverse aspects of plant proteases research.
Author : Alan J. Barrett
Publisher : Elsevier Publishing Company
ISBN 13 :
Total Pages : 694 pages
Book Rating : 4.3/5 (91 download)
Download or read book Proteinase Inhibitors written by Alan J. Barrett and published by Elsevier Publishing Company. This book was released on 1986 with total page 694 pages. Available in PDF, EPUB and Kindle. Book excerpt: The twelfth volume in this well established series presents the latest research on proteinases, which are known or suspected to be implicated in many aspects of normal physiology and disease processes. In order to understand the nature of this involvement the researcher must repeatedly resort to our current understanding of proteinase inhibitors. The chapters in this book cover various approaches to the investigation and treatment of a wide variety of medical problems, including malignancy, arthritis, hypertension and coagulation disorders, viral, bacterial and parasitic infections, muscular dystrophy, pulmonary emphysema and neurological disease. Due to the level of sophistication of naturally occurring protein inhibitors, techniques such as X-ray crystallography are being used intensively, and the results are being fed back into the design of artificial inhibitors made chemically or by genetic engineering. Rapid technical progress in these synthetic methods encourages the full use of new information available, and the outcome is that a range of new drugs are in the stage of pre-clinical trials.
Author : Alan J. Barrett
Publisher : Elsevier
ISBN 13 : 0080984150
Total Pages : 1182 pages
Book Rating : 4.0/5 (89 download)
Download or read book Handbook of Proteolytic Enzymes, Volume 1 written by Alan J. Barrett and published by Elsevier. This book was released on 2012-12-02 with total page 1182 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Proteolytic Enzymes, Second Edition, Volume 1: Aspartic and Metallo Peptidases is a compilation of numerous progressive research studies on proteolytic enzymes. This edition is organized into two main sections encompassing 328 chapters. This handbook is organized around a system for the classification of peptidases, which is a hierarchical one built on the concepts of catalytic type, clan, family and peptidase. The concept of catalytic type of a peptidase depends upon the chemical nature of the groups responsible for catalysis. The recognized catalytic types are aspartic, cysteine, metallo, serine, threonine, and the unclassified enzymes, while clans and families are groups of homologous peptidases. Homology at the level of a family of peptidases is shown by statistically significant relationship in amino acid sequence to a representative member called the type example, or to another member of the family that has already been shown to be related to the type example. Each chapter discusses the history, activity, specificity, structural chemistry, preparation, and biological aspects of the enzyme. This book will prove useful to enzyme chemists and researchers.
Author : Satya Prakash Gupta
Publisher : Academic Press
ISBN 13 : 0128181680
Total Pages : 524 pages
Book Rating : 4.1/5 (281 download)
Download or read book Cancer-Leading Proteases written by Satya Prakash Gupta and published by Academic Press. This book was released on 2020-02-03 with total page 524 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer-Leading Proteases: Structures, Functions, and Inhibition presents a detailed discussion on the role of proteases as drug targets and how they have been utilized to develop anticancer drugs. Proteases possess outstanding diversity in their functions. Because of their unique properties, proteases are a major focus of attention for the pharmaceutical industry as potential drug targets or as diagnostic and prognostic biomarkers. This book covers the structure and functions of proteases and the chemical and biological rationale of drug design relating to how these proteases can be exploited to find useful chemotherapeutics to fight cancers. In addition, the book encompasses the experimental and theoretical aspects of anticancer drug design based on proteases. It is a useful resource for pharmaceutical scientists, medicinal chemists, biochemists, microbiologists, and cancer researchers working on proteases. Explains the role of proteases in the biology of cancer Discusses how proteases can be used as potential drug targets or as diagnostic and prognostic biomarkers Covers a wide range of cancers and provides detailed discussions on protease examples
Author : Catharine Jane Collar
Publisher :
ISBN 13 :
Total Pages : 184 pages
Book Rating : 4.:/5 (857 download)
Download or read book Molecular Modeling of Four Aspartic Protease Enzymes and Their Inhibitors written by Catharine Jane Collar and published by . This book was released on 2006 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Vito Turk
Publisher : Pergamon
ISBN 13 :
Total Pages : 410 pages
Book Rating : 4.E/5 ( download)
Download or read book Proteinases and Their Inhibitors written by Vito Turk and published by Pergamon. This book was released on 1981 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt:
