Agriculture, Rural Development, Food and Drug Administration, and Related Agencies Appropriations for 2008

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Publisher :
ISBN 13 :
Total Pages : 700 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Agriculture, Rural Development, Food and Drug Administration, and Related Agencies Appropriations for 2008 by : United States. Congress. House. Committee on Appropriations Subcommittee on Agriculture, Rural Development, Food and Drug Administration, and Related Agencies

Download or read book Agriculture, Rural Development, Food and Drug Administration, and Related Agencies Appropriations for 2008 written by United States. Congress. House. Committee on Appropriations Subcommittee on Agriculture, Rural Development, Food and Drug Administration, and Related Agencies and published by . This book was released on 2007 with total page 700 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Drug-Drug Interactions

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Publisher : CRC Press
ISBN 13 : 0849375940
Total Pages : 769 pages
Book Rating : 4.8/5 (493 download)

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Book Synopsis Drug-Drug Interactions by : A. David Rodrigues

Download or read book Drug-Drug Interactions written by A. David Rodrigues and published by CRC Press. This book was released on 2019-01-03 with total page 769 pages. Available in PDF, EPUB and Kindle. Book excerpt: Authored by renowned leaders in the field, this comprehensive volume covers all aspects of drug-drug interactions, including preclinical, clinical, toxicological, and regulatory perspectives.Thoroughly updated, this second edition reflects the significant advances and includes extensive new material on:key interplay between transporters and enzymes

Bayesian Pharmacokinetic Model-Based Drug-Drug Interaction Prediction

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Publisher :
ISBN 13 :
Total Pages : 276 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Bayesian Pharmacokinetic Model-Based Drug-Drug Interaction Prediction by : Jihao Zhou

Download or read book Bayesian Pharmacokinetic Model-Based Drug-Drug Interaction Prediction written by Jihao Zhou and published by . This book was released on 2007 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt:

International Congress Calendar

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ISBN 13 :
Total Pages : 388 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis International Congress Calendar by :

Download or read book International Congress Calendar written by and published by . This book was released on 2004 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Antiviral Drugs

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Publisher : John Wiley & Sons
ISBN 13 : 0470934689
Total Pages : 472 pages
Book Rating : 4.4/5 (79 download)

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Book Synopsis Antiviral Drugs by : Wieslaw M. Kazmierski

Download or read book Antiviral Drugs written by Wieslaw M. Kazmierski and published by John Wiley & Sons. This book was released on 2011-07-08 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on new small molecule approaches to combat viral infections. The chapters describe the discovery and development from bench through the clinic of relatively recently-approved antiviral drugs and compounds in advanced clinical development. Organized by a virus (such as HIV, HCV, RSV, influenza, HBV and CMV) and written by top academic and industrial authorities in the field, the book provides a unique opportunity to study, understand and apply discovery and development principles and learning without the need for an individual to research, analyze and synthesize all immense sourcing references. Topics showcase challenges and solutions of issues encountered, offering tremendous experience accumulated over many years of research that will be particularly useful to basic and bench scientists as well as clinicians as they continue discovering and developing new drugs and therapies.

Preclinical Drug Development

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Publisher : CRC Press
ISBN 13 : 1420084739
Total Pages : 374 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Preclinical Drug Development by : Mark Rogge

Download or read book Preclinical Drug Development written by Mark Rogge and published by CRC Press. This book was released on 2016-04-19 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: Preclinical Drug Development, Second Edition discusses the broad and complicated realm of preclinical drug development. Topics range from assessment of pharmacology and toxicology to industry trends and regulatory expectations to requirements that support clinical trials. Highlights of the Second Edition include: PharmacokineticsModeling and simula

Encyclopedia of Associations

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Publisher :
ISBN 13 : 9780787682866
Total Pages : 1492 pages
Book Rating : 4.6/5 (828 download)

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Book Synopsis Encyclopedia of Associations by :

Download or read book Encyclopedia of Associations written by and published by . This book was released on 2006-12 with total page 1492 pages. Available in PDF, EPUB and Kindle. Book excerpt:

National Trade and Professional Associations of the United States

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Publisher :
ISBN 13 :
Total Pages : 1130 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis National Trade and Professional Associations of the United States by :

Download or read book National Trade and Professional Associations of the United States written by and published by . This book was released on 2007 with total page 1130 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Emerging Roles of TRP Channels in Brain Pathology

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Publisher : Frontiers Media SA
ISBN 13 : 2889711307
Total Pages : 213 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Emerging Roles of TRP Channels in Brain Pathology by : Bilal ÇİĞ

Download or read book Emerging Roles of TRP Channels in Brain Pathology written by Bilal ÇİĞ and published by Frontiers Media SA. This book was released on 2021-08-02 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Ion Channel Drug Discovery

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Publisher : Royal Society of Chemistry
ISBN 13 : 1849735085
Total Pages : 385 pages
Book Rating : 4.8/5 (497 download)

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Book Synopsis Ion Channel Drug Discovery by : Brian Cox

Download or read book Ion Channel Drug Discovery written by Brian Cox and published by Royal Society of Chemistry. This book was released on 2014-09-03 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ion channel drug discovery is a rapidly evolving field fuelled by recent, but significant, advances in our understanding of ion channel function combined with enabling technologies such as automated electrophysiology. The resurgent interest in this target class by both pharmaceutical and academic scientists was clearly highlighted by the over-subscribed RSC/BPS 'Ion Channels as Therapeutic Targets' symposium in February 2009. This book builds on the platform created by that meeting, covering themes including advances in screening technology, ion channel structure and modelling and up-to-date case histories of the discovery of modulators of a range of channels, both voltage-gated and non-voltage-gated channels. The editors have built an extensive network of contacts in the field through their first-hand scientific experience, collaborations and conference participation and the organisation of the meeting at Novartis, Horsham, increased the network enabling the editors to draw on the experience of eminent researchers in the field. Interest and investment in ion channel modulation in both industrial and academic settings continues to grow as new therapeutic opportunities are identified and realised for ion channel modulation. This book provides a reference text by covering a combination of recent advances in the field, from technological and medicinal chemistry perspectives, as well as providing an introduction to the new 'ion channel drug discoverer'. The book has contributions from highly respected academic researchers, industrial researchers at the cutting edge of drug discovery and experts in enabling technology. This combination provides a complete picture of the field of interest to a wide range of readers.

Antitargets and Drug Safety

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Publisher : John Wiley & Sons
ISBN 13 : 3527673679
Total Pages : 528 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Antitargets and Drug Safety by : Laszlo Urban

Download or read book Antitargets and Drug Safety written by Laszlo Urban and published by John Wiley & Sons. This book was released on 2015-02-23 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: With its focus on emerging concerns of kinase and GPCR-mediated antitarget effects, this vital reference for drug developers addresses one of the hot topics in drug safety now and in future. Divided into three major parts, the first section deals with novel technologies and includes the utility of adverse event reports to drug discovery, the translational aspects of preclinical safety findings, broader computational prediction of drug side-effects, and a description of the serotonergic system. The main part of the book looks at some of the most common antitarget-mediated side effects, focusing on hepatotoxicity in drug safety, cardiovascular toxicity and signaling effects via kinase and GPCR anti-targets. In the final section, several case studies of recently developed drugs illustrate how to prevent anti-target effects and how big pharma deals with them if they occur. The more recent field of systems pharmacology has gained prominence and this is reflected in chapters dedicated to the utility in deciphering and modeling anti-targets. The final chapter is concerned with those compounds that inadvertently elicit CNS mediated adverse events, including a pragmatic description of ways to mitigate these types of safety risks. Written as a companion to the successful book on antitargets by Vaz and Klabunde, this new volume focuses on recent progress and new classes, methods and case studies that were not previously covered.

Principles of Safety Pharmacology

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Publisher : Springer
ISBN 13 : 366246943X
Total Pages : 477 pages
Book Rating : 4.6/5 (624 download)

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Book Synopsis Principles of Safety Pharmacology by : Michael K. Pugsley

Download or read book Principles of Safety Pharmacology written by Michael K. Pugsley and published by Springer. This book was released on 2015-06-19 with total page 477 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book illustrates, in a comprehensive manner, the most current areas of importance to Safety Pharmacology, a burgeoning unique pharmacological discipline with important ties to academia, industry and regulatory authorities. It provides readers with a definitive collection of topics containing essential information on the latest industry guidelines and overviews current and breakthrough topics in both functional and molecular pharmacology. An additional novelty of the book is that it constitutes academic, pharmaceutical and biotechnology perspectives for Safety Pharmacology issues. Each chapter is written by an expert in the area and includes not only a fundamental background regarding the topic but also detailed descriptions of currently accepted, validated models and methods as well as innovative methodologies used in drug discovery.

Clinical Trial Simulations

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Publisher : Springer Science & Business Media
ISBN 13 : 1441974156
Total Pages : 540 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Clinical Trial Simulations by : Holly H. C. Kimko

Download or read book Clinical Trial Simulations written by Holly H. C. Kimko and published by Springer Science & Business Media. This book was released on 2010-12-09 with total page 540 pages. Available in PDF, EPUB and Kindle. Book excerpt: This edition includes both updates and new uses and issues concerning CTS, along with case studies of how clinical trial simulations are being applied in various therapeutic and application areas. Importantly, the book expands on the utility of CTS for informing decisions during drug development and regulatory review. Each chapter author was selected on the basis of demonstrated expertise in state-of-the-art application of CTS. The target audience for this volume includes researchers and scientists who wish to consider use of simulations in the design, analysis, or regulatory review and guidance of clinical trials. This book does not embrace all aspects of trial design, nor is it intended as a complete recipe for using computers to design trials. Rather, it is an information source that enables the reader to gain understanding of essential background and knowledge for practical applications of simulation for clinical trial design and analysis. It is assumed that the reader has a working understanding of pharmacokinetics and pharmacodynamics, modeling, pharmacometric analyses, and/or the drug development and regulatory processes.

Studies in Malaria

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Publisher :
ISBN 13 :
Total Pages : 288 pages
Book Rating : 4.:/5 (1 download)

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Book Synopsis Studies in Malaria by : Hugh Stott

Download or read book Studies in Malaria written by Hugh Stott and published by . This book was released on 1916 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Handbook of Bioequivalence Testing

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Publisher : CRC Press
ISBN 13 : 1482226383
Total Pages : 992 pages
Book Rating : 4.4/5 (822 download)

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Book Synopsis Handbook of Bioequivalence Testing by : Sarfaraz K. Niazi

Download or read book Handbook of Bioequivalence Testing written by Sarfaraz K. Niazi and published by CRC Press. This book was released on 2014-10-29 with total page 992 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the generic pharmaceutical industry continues to grow and thrive, so does the need to conduct adequate, efficient bioequivalence studies. In recent years, there have been significant changes to the statistical models for evaluating bioequivalence. In addition, advances in the analytical technology used to detect drug and metabolite levels have m

Drug Transporters

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Publisher : Springer Science & Business Media
ISBN 13 : 3642145418
Total Pages : 457 pages
Book Rating : 4.6/5 (421 download)

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Book Synopsis Drug Transporters by : Martin F. Fromm

Download or read book Drug Transporters written by Martin F. Fromm and published by Springer Science & Business Media. This book was released on 2010-11-19 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is increasingly recognized that various transporter proteins are expressed throughout the body and determine absorption, tissue distribution, biliary and renal elimination of endogenous compounds and drugs and drug effects. This book will give an overview on the transporter families which are most important for drug therapy. Most chapters will focus on one transporter family highlighting tissue expression, substrates, inhibitors, knock-out mouse models and clinical studies.

Regulated Bioanalysis: Fundamentals and Practice

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Publisher : Springer
ISBN 13 : 3319548026
Total Pages : 239 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Regulated Bioanalysis: Fundamentals and Practice by : Mario L. Rocci Jr.

Download or read book Regulated Bioanalysis: Fundamentals and Practice written by Mario L. Rocci Jr. and published by Springer. This book was released on 2017-04-24 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: The editors have engaged leading scientists in the field to participate in the development of this book, which is envisioned as a “one of a kind” contribution to the field. The book is a comprehensive text that puts fundamental bioanalytical science in context with current practice, its challenges and ongoing developments. It expands on existing texts on the subject by covering regulated bioanalysis of both small and large molecule therapeutics from both a scientific and regulatory viewpoint. The content will be useful to a wide spectrum of readers: from those new to bioanalysis; to those developing their experience in the laboratory, or working in one of the many critical supporting roles; to seasoned practitioners looking for a solid source of information on this exciting and important discipline.