Aquaporin Regulation

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Aquaporin Regulation

Author : Gerald Litwack
Publisher : Academic Press
ISBN 13 : 0128208104
Total Pages : 376 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Aquaporin Regulation by : Gerald Litwack

Download or read book Aquaporin Regulation written by Gerald Litwack and published by Academic Press. This book was released on 2020-02-13 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aquaporin Regulation, Volume 112, the latest release in the Vitamins and Hormones series, highlights new advances in the field, with this new volume presenting interesting chapters highlighting Perspectives on the evolution of aquaporin superfamily, Structure and dynamics of aquaporin-1, Selectivity and Transport in Aquaporins from Molecular Simulation Studies, Aquaporin regulation in metabolic organs, Phosphorylation of human AQP2 and its role in trafficking, Regulation of Aquaporin-2 by RNA Interference, Aquaporin Regulation: Lessons from Secretory Vesicles, CFTR Regulation of Aquaporin-mediated Water Transport, Glucocorticoid Gene Regulation of Aquaporin-7, and much more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Vitamins and Hormones series Updated release includes the latest information on aquaporin regulation

Aquaporin Regulation

Author : Gerald Litwack
Publisher : Academic Press
ISBN 13 : 0128208090
Total Pages : 374 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Aquaporin Regulation by : Gerald Litwack

Download or read book Aquaporin Regulation written by Gerald Litwack and published by Academic Press. This book was released on 2020-02-27 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aquaporin Regulation, Volume 112, the latest release in the Vitamins and Hormones series, highlights new advances in the field, with this new volume presenting interesting chapters highlighting Perspectives on the evolution of aquaporin superfamily, Structure and dynamics of aquaporin-1, Selectivity and Transport in Aquaporins from Molecular Simulation Studies, Aquaporin regulation in metabolic organs, Phosphorylation of human AQP2 and its role in trafficking, Regulation of Aquaporin-2 by RNA Interference, Aquaporin Regulation: Lessons from Secretory Vesicles, CFTR Regulation of Aquaporin-mediated Water Transport, Glucocorticoid Gene Regulation of Aquaporin-7, and much more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Vitamins and Hormones series Updated release includes the latest information on aquaporin regulation

Plant Aquaporins

Author : François Chaumont
Publisher : Springer
ISBN 13 : 3319493957
Total Pages : 353 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Plant Aquaporins by : François Chaumont

Download or read book Plant Aquaporins written by François Chaumont and published by Springer. This book was released on 2017-02-07 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aquaporins are channel proteins that facilitate the diffusion of water and small uncharged solutes across cellular membranes. Plant aquaporins form a large family of highly divergent proteins that are involved in many different physiological processes. This book will summarize the recent advances regarding plant aquaporins, their phylogeny, structure, substrate specificity, mechanisms of regulation and roles in various important physiological processes related to the control of water flow and small solute distribution at the cell, tissue and plant level in an ever-changing environment.

Aquaporins

Author : Eric Beitz
Publisher : Springer Science & Business Media
ISBN 13 : 3540798854
Total Pages : 425 pages
Book Rating : 4.5/5 (47 download)

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Book Synopsis Aquaporins by : Eric Beitz

Download or read book Aquaporins written by Eric Beitz and published by Springer Science & Business Media. This book was released on 2008-12-19 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aquaporin field has matured at an exceptionally fast pace and we are at the verge to develop serious strategies to therapeutically modulate aquaporin function directly or via regulatory networks. Key prerequisites are available today: i. a considerable (and growing) number of aquaporin crystal structures for the rational design of inhibitory molecules, ii. elaborate molecular dynamics simulation techniques for theoretical analyses of selectivity mechanisms and docking experiments, iii. comprehensive data on aquaporin immunohistochemistry, iv. aquaporin knockout animals for physiological studies, and v. assay systems for compound library screenings. The structure of this volume on aquaporins follows the points laid out above and thus covers the developments from basic research to potential pharmacological use. Situated between pharmacology textbooks and recent scientific papers this book provides a timely overview for readers from the fundamental as well as the applied disciplines.

Water Channels

Author : Alan S. Verkman
Publisher :
ISBN 13 :
Total Pages : 136 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Water Channels by : Alan S. Verkman

Download or read book Water Channels written by Alan S. Verkman and published by . This book was released on 1993 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Aquaporins: Dynamic Role and Regulation

Author : Rupesh K. Deshmukh
Publisher : Frontiers Media SA
ISBN 13 : 2889452891
Total Pages : 185 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis Aquaporins: Dynamic Role and Regulation by : Rupesh K. Deshmukh

Download or read book Aquaporins: Dynamic Role and Regulation written by Rupesh K. Deshmukh and published by Frontiers Media SA. This book was released on 2017-10-10 with total page 185 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aquaporins (AQPs), a class of integral membrane proteins, form channels facilitating movement of water and many other solutes. In solute transport systems of all living organisms including plants, animals and fungi, AQPs play a vital role. Plants contain a much higher number of AQP genes compared to animals, the likely consequence of genome duplication events and higher ploidy levels. As a result of duplication and subsequent diversification, plant AQPs have evolved several subfamilies with very diverse functions. Plant AQPs are highly selective for specific solutes because of their unique structural features. For instance, ar/R selectivity filters and NPA domains have been found to be key elements in governing solute permeability through the AQP channels. Combination of conserved motifs and specific amino acids influencing pore morphology appears to regulate the permeability of specific solutes such as water, urea, CO2, H2O2, boric acid, silicic acid and many more. The discovery of novel AQPs has been accelerated over the last few years with the increasing availability of genomic and transcriptomic data. The expanding number of well characterised AQPs provides opportunities to understand factors influencing water transport, nutritional uptake, and elemental balance. Homology-based search tools and phylogenetic analyses offer efficient strategies for AQP identification. Subsequent characterization can be based on different approaches involving proteomics, genomics, and transcriptomic tools. The combination of these technological advances make it possible to efficiently study the inter-dependency of AQPs, regulation through phosphorylation and reversible phosphorylation, networking with other transporters, structural features, pH gating systems, trafficking and degradation. Several studies have supported the role of AQPs in differential phenotypic responses to abiotic and biotic stress in plants. Crop improvement programs aiming for the development of cultivars with higher tolerance against stresses like drought, flooding, salinity and many biotic diseases, can explore and exploit the finely tuned AQP-regulated transport system. For instance, a promising approach in crop breeding programs is the utilization of genetic variation in AQPs for the development of stress tolerant cultivars. Similarly, transgenic and mutagenesis approaches provide an opportunity to better understand the AQP transport system with subsequent applications for the development of climate-smart drought-tolerant cultivars. The contributions to this Frontiers in Plant Science Research Topic have highlighted the evolution and phylogenetic distribution of AQPs in several plant species. Numerous aspects of regulation that seek to explain AQP-mediated transport system have been addressed. These contributions will help to improve our understanding of AQPs and their role in important physiological aspects and will bring AQP research closer to practical applications.

Encyclopedia of Signaling Molecules

Author :
Publisher :
ISBN 13 : 9781461464389
Total Pages : pages
Book Rating : 4.4/5 (643 download)

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Book Synopsis Encyclopedia of Signaling Molecules by :

Download or read book Encyclopedia of Signaling Molecules written by and published by . This book was released on 19?? with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Aquaporins in Health and Disease

Author : Graca Soveral
Publisher : CRC Press
ISBN 13 : 149870784X
Total Pages : 356 pages
Book Rating : 4.4/5 (987 download)

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Book Synopsis Aquaporins in Health and Disease by : Graca Soveral

Download or read book Aquaporins in Health and Disease written by Graca Soveral and published by CRC Press. This book was released on 2018-10-30 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the discovery of Aquaporin-1 (AQP1) as a water channel, many studies have revealed the importance of aquaporins in mammalian physiology and pathophysiology as well as plant and microbial biology. The studies have also shown aquaporins as potential drug targets and targets for improving crop properties. Written by an international group of contributors at the forefront of the field, Aquaporins in Health and Disease: New Molecular Targets for Drug Discovery presents the latest research advances in aquaporins and other major intrinsic protein (MIP) channels. The first section of the book describes the general concepts of aquaporin channel function, genomic research, structure-function analysis of aquaporins and glycerol facilitators, and regulation by gating and trafficking, including yeast aquaporin regulation and function. The second section discusses the physiological and pathophysiological roles of aquaporins in humans and microbes. The final section covers the development of inhibitors of aquaporin function. The book’s epilogue offers future perspectives and directions, mainly in the area of aquaporin-based diagnostics and therapeutics. Stimulating future research on this important protein family, this book facilitates a paradigm shift in the understanding and roles of aquaporin membrane proteins in all biological settings. It encourages scientists to develop novel approaches for the treatment of human diseases based on aquaporin function or dysfunction.

Protective Chemical Agents in the Amelioration of Plant Abiotic Stress

Author : Aryadeep Roychoudhury
Publisher : John Wiley & Sons
ISBN 13 : 1119551633
Total Pages : 698 pages
Book Rating : 4.1/5 (195 download)

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Book Synopsis Protective Chemical Agents in the Amelioration of Plant Abiotic Stress by : Aryadeep Roychoudhury

Download or read book Protective Chemical Agents in the Amelioration of Plant Abiotic Stress written by Aryadeep Roychoudhury and published by John Wiley & Sons. This book was released on 2020-07-07 with total page 698 pages. Available in PDF, EPUB and Kindle. Book excerpt: A guide to the chemical agents that protect plants from various environmental stressors Protective Chemical Agents in the Amelioration of Plant Abiotic Stress offers a guide to the diverse chemical agents that have the potential to mitigate different forms of abiotic stresses in plants. Edited by two experts on the topic, the book explores the role of novel chemicals and shows how using such unique chemical agents can tackle the oxidative damages caused by environmental stresses. Exogenous application of different chemical agents or chemical priming of seeds presents opportunities for crop stress management. The use of chemical compounds as protective agents has been found to improve plant tolerance significantly in various crop and non-crop species against a range of different individually applied abiotic stresses by regulating the endogenous levels of the protective agents within plants. This important book: Explores the efficacy of various chemical agents to eliminate abiotic stress Offers a groundbreaking look at the topic and reviews the most recent advances in the field Includes information from noted authorities on the subject Promises to benefit agriculture under stress conditions at the ground level Written for researchers, academicians, and scientists, Protective Chemical Agents in the Amelioration of Plant Abiotic Stress details the wide range of protective chemical agents, their applications, and their intricate biochemical and molecular mechanism of action within the plant systems during adverse situations.

Aquaporins

Author : Baoxue Yang
Publisher : Springer
ISBN 13 : 9402410570
Total Pages : 278 pages
Book Rating : 4.4/5 (24 download)

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Book Synopsis Aquaporins by : Baoxue Yang

Download or read book Aquaporins written by Baoxue Yang and published by Springer. This book was released on 2017-03-03 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a state-of-the-art report on our current understanding of aquaporins and the future direction of the field. Aquaporins (AQPs) are a group of water-channel proteins that are specifically permeable to water and other small molecules, such as glycerol and urea. To date thirteen water-channel proteins (AQP0 – AQP12) have been cloned and the mechanisms and physiological functions of water transport across biological membranes have long been the subject of interest. Recent advances in the molecular biology and physiology of water transport have yielded new insights into how and why water moves across cell membranes, and studies on aquaporin knockout mouse models suggest that aquaporins are involved in the development of some diseases and they may be useful targets of research into selective-inhibitor drugs. By focusing on the advances made over the last 20 years in the biophysics, genetics, protein structure, molecular biology, physiology, pathophysiology and pharmacology of aquaporins in mammalian cell membranes, this book provides novel insights into further mechanisms and the physiological significance of water and some small molecule transport in mammals in order to stimulate further research in new directions.

Epigenetics in Plants of Agronomic Importance: Fundamentals and Applications

Author : Raúl Alvarez-Venegas
Publisher : Springer
ISBN 13 : 3319079719
Total Pages : 158 pages
Book Rating : 4.3/5 (19 download)

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Book Synopsis Epigenetics in Plants of Agronomic Importance: Fundamentals and Applications by : Raúl Alvarez-Venegas

Download or read book Epigenetics in Plants of Agronomic Importance: Fundamentals and Applications written by Raúl Alvarez-Venegas and published by Springer. This book was released on 2014-07-22 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past decades, chromatin remodelling has emerged as an important regulator of gene expression and plant defense. This book provides a detailed understanding of the epigenetic mechanisms involved in plants of agronomic importance. The information presented here is significant because it is expected to provide the knowledge needed to develop in the future treatments to manipulate and selectively activate/inhibit proteins and metabolic pathways to counter pathogens, to treat important diseases and to increase crop productivity. New approaches of this kind and the development of new technologies will certainly increase our knowledge of currently known post-translational modifications and facilitate the understanding of their roles in, for example, host-pathogen interactions and crop productivity. Furthermore, we provide important insight on how the plant epigenome changes in response to developmental or environmental stimuli, how chromatin modifications are established and maintained, to which degree they are used throughout the genome, and how chromatin modifications influence each another.

Vascular Transport in Plants

Author : N. Michelle Holbrook
Publisher : Elsevier
ISBN 13 : 0080454232
Total Pages : 597 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Vascular Transport in Plants by : N. Michelle Holbrook

Download or read book Vascular Transport in Plants written by N. Michelle Holbrook and published by Elsevier. This book was released on 2011-09-06 with total page 597 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vascular Transport in Plants provides an up-to-date synthesis of new research on the biology of long distance transport processes in plants. It is a valuable resource and reference for researchers and graduate level students in physiology, molecular biology, physiology, ecology, ecological physiology, development, and all applied disciplines related to agriculture, horticulture, forestry and biotechnology. The book considers long-distance transport from the perspective of molecular level processes to whole plant function, allowing readers to integrate information relating to vascular transport across multiple scales. The book is unique in presenting xylem and phloem transport processes in plants together in a comparative style that emphasizes the important interactions between these two parallel transport systems. Includes 105 exceptional figures Discusses xylem and phloem transport in a single volume, highlighting their interactions Syntheses of structure, function and biology of vascular transport by leading authorities Poses unsolved questions and stimulates future research Provides a new conceptual framework for vascular function in plants

Human Biochemistry

Author : Gerald Litwack
Publisher : Academic Press
ISBN 13 : 032391053X
Total Pages : 883 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Human Biochemistry by : Gerald Litwack

Download or read book Human Biochemistry written by Gerald Litwack and published by Academic Press. This book was released on 2021-11-28 with total page 883 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human Biochemistry, Second Edition provides a comprehensive, pragmatic introduction to biochemistry as it relates to human development and disease. Here, Gerald Litwack, award-wining researcher and longtime teacher, discusses the biochemical aspects of organ systems and tissue, cells, proteins, enzymes, insulins and sugars, lipids, nucleic acids, amino acids, polypeptides, steroids, and vitamins and nutrition, among other topics. Fully updated to address recent advances, the new edition features fresh discussions on hypothalamic releasing hormones, DNA editing with CRISPR, new functions of cellular prions, plant-based diet and nutrition, and much more. Grounded in problem-driven learning, this new edition features clinical case studies, applications, chapter summaries, and review-based questions that translate basic biochemistry into clinical practice, thus empowering active clinicians, students and researchers. Presents an update on a past edition winner of the 2018 Most Promising New Textbook (College) Award (Texty) from the Textbook and Academic Authors Association and the PROSE Award of the Association of American Publishers Provides a fully updated resource on current research in human and medical biochemistry Includes clinical case studies, applications, chapter summaries and review-based questions Adopts a practice-based approach, reflecting the needs of both researchers and clinically oriented readers

Nephrology and Fluid/Electrolyte Physiology

Author : William Oh
Publisher : Elsevier Health Sciences
ISBN 13 : 0323568777
Total Pages : 400 pages
Book Rating : 4.3/5 (235 download)

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Book Synopsis Nephrology and Fluid/Electrolyte Physiology by : William Oh

Download or read book Nephrology and Fluid/Electrolyte Physiology written by William Oh and published by Elsevier Health Sciences. This book was released on 2018-06-25 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr. Richard Polin’s Neonatology Questions and Controversies series highlights the most challenging aspects of neonatal care, offering trustworthy guidance on up-to-date diagnostic and treatment options in the field. In each volume, renowned experts address the clinical problems of greatest concern to today’s practitioners, helping you handle difficult practice issues and provide optimal, evidence-based care to every patient. Stay fully up to date in this fast-changing field with Nephrology and Fluid/Electrolyte Physiology, 3rd Edition. New chapters on Inherited Disorders of Calcium, Phosphate and Magnesium; Fluid and Electrolyte Management of High Risk Infants; Renal Development and Molecular Pathogenesis of Renal Dysplasia; and Prenatal Programming, which describes how prenatal insults can result in hypertension, kidney and cardiovascular disease. The most current clinical information, including new content on the molecular basis for hereditary tubulopathies and inherited disorders of calcium, phosphate, and magnesium homeostasis. New information on genetics and pharmacology, neonatal hypertension, diuretic use in the newborn, prenatal programming of adult diseases, lung fluid balance, and much more. Consistent chapter organization to help you find information quickly and easily. The most authoritative advice available from world-class neonatologists who share their knowledge of new trends and developments in neonatal care. Purchase each volume individually, or get the entire 7-volume set! Gastroenterology and Nutrition Hematology, Immunology and Genetics Hemodynamics and Cardiology Infectious Disease and Pharmacology New Volume! Nephrology and Fluid/Electrolyte Physiology Neurology The Newborn Lung

Abiotic Stress in Plants

Author : Shah Fahad
Publisher : BoD – Books on Demand
ISBN 13 : 1838810552
Total Pages : 496 pages
Book Rating : 4.8/5 (388 download)

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Book Synopsis Abiotic Stress in Plants by : Shah Fahad

Download or read book Abiotic Stress in Plants written by Shah Fahad and published by BoD – Books on Demand. This book was released on 2021-07-21 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: Environmental insults such as extremes of temperature, extremes of water status, and deteriorating soil conditions pose major threats to agriculture and food security. Employing contemporary tools and techniques from all branches of science, attempts are being made worldwide to understand how plants respond to abiotic stresses with the aim to manipulate plant performance that is better suited to withstand these stresses. This book searches for possible answers to several basic questions related to plant responses towards abiotic stresses. Synthesizing developments in plant stress biology, the book offers strategies that can be used in breeding, including genomic, molecular, physiological, and biotechnological approaches that have the potential to develop resilient plants and improve crop productivity worldwide.

Molecular Biology and Physiology of Water and Solute Transport

Author : Stefan Hohmann
Publisher : Springer Science & Business Media
ISBN 13 : 9780306465017
Total Pages : 480 pages
Book Rating : 4.4/5 (65 download)

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Book Synopsis Molecular Biology and Physiology of Water and Solute Transport by : Stefan Hohmann

Download or read book Molecular Biology and Physiology of Water and Solute Transport written by Stefan Hohmann and published by Springer Science & Business Media. This book was released on 2000 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biophysical studies in the 1950ies and 1960ies led to the realization that the water permeability of certain biological membranes must be due to the presence of water transporting proteins. This hypothesis was confirmed in 1991 and 1992 with the pioneering discovery of the first molecular membrane water channel, CHIP28, by Agre and coworkers. This integral membrane protein, which is abundant in the erythrocyte membrane and in many epithelial cells, is now called aquaporin-1 or AQP1. Thus the terms water channel or aquaporin are synonymous. In July 2000 more than 200 researchers came together in Gothenburg, Sweden, for the `3rd International Conference on the Molecular Biology and Physiology of Water and Solute Transport" to discuss progress in this emerging research field. 58 different presentations from this conference are the basis for this book. Cumulatively, these 58 short chapters provide a balanced overview complementing numerous recent reviews in this field.

REGULATION OF AQUAPORIN-1 ION CHANNEL FUNCTION BY INTRACELLULAR SIGNALING PATHWAYS.

Author :
Publisher :
ISBN 13 :
Total Pages : 406 pages
Book Rating : 4.:/5 (137 download)

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Book Synopsis REGULATION OF AQUAPORIN-1 ION CHANNEL FUNCTION BY INTRACELLULAR SIGNALING PATHWAYS. by :

Download or read book REGULATION OF AQUAPORIN-1 ION CHANNEL FUNCTION BY INTRACELLULAR SIGNALING PATHWAYS. written by and published by . This book was released on 2005 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: My dissertation work has focused on identifying regulatory mechanisms that govern Cyclic Guanosine Monophosphate (cGMP)-activation of Aquaprorin-1 (Aqp1) ion channels. Aquaporins serve as pores for water thus allowing enhanced water permeability in biological membranes (Preston, et al., 1992). A subset of Aquaporin proteins behave as ion channels regulated by intracellular signaling pathways (Anthony, et al., 2000; Ehring, et al., 1990; Yasui, et al., 1999a). cGMP is necessary for Aqp1 ion channel activation, but only a small subpopulation of Aqp1 proteins function as cGMP-activated ion channels. This observation indicates the involvement of additional regulatory mechanisms in the gating Aqp1 ion channels.