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Approaches To Improve The Precision Of Similarity Patterns And Reproducibility For Cluster Analysis
Download Approaches To Improve The Precision Of Similarity Patterns And Reproducibility For Cluster Analysis full books in PDF, epub, and Kindle. Read online Approaches To Improve The Precision Of Similarity Patterns And Reproducibility For Cluster Analysis ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Author :National Academies of Sciences, Engineering, and Medicine Publisher :National Academies Press ISBN 13 :0309486165 Total Pages :257 pages Book Rating :4.3/5 (94 download)
Book Synopsis Reproducibility and Replicability in Science by : National Academies of Sciences, Engineering, and Medicine
Download or read book Reproducibility and Replicability in Science written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2019-10-20 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the pathways by which the scientific community confirms the validity of a new scientific discovery is by repeating the research that produced it. When a scientific effort fails to independently confirm the computations or results of a previous study, some fear that it may be a symptom of a lack of rigor in science, while others argue that such an observed inconsistency can be an important precursor to new discovery. Concerns about reproducibility and replicability have been expressed in both scientific and popular media. As these concerns came to light, Congress requested that the National Academies of Sciences, Engineering, and Medicine conduct a study to assess the extent of issues related to reproducibility and replicability and to offer recommendations for improving rigor and transparency in scientific research. Reproducibility and Replicability in Science defines reproducibility and replicability and examines the factors that may lead to non-reproducibility and non-replicability in research. Unlike the typical expectation of reproducibility between two computations, expectations about replicability are more nuanced, and in some cases a lack of replicability can aid the process of scientific discovery. This report provides recommendations to researchers, academic institutions, journals, and funders on steps they can take to improve reproducibility and replicability in science.
Book Synopsis Dissertation Abstracts International by :
Download or read book Dissertation Abstracts International written by and published by . This book was released on 2009 with total page 840 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Computational Genomics with R by : Altuna Akalin
Download or read book Computational Genomics with R written by Altuna Akalin and published by CRC Press. This book was released on 2020-12-16 with total page 463 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational Genomics with R provides a starting point for beginners in genomic data analysis and also guides more advanced practitioners to sophisticated data analysis techniques in genomics. The book covers topics from R programming, to machine learning and statistics, to the latest genomic data analysis techniques. The text provides accessible information and explanations, always with the genomics context in the background. This also contains practical and well-documented examples in R so readers can analyze their data by simply reusing the code presented. As the field of computational genomics is interdisciplinary, it requires different starting points for people with different backgrounds. For example, a biologist might skip sections on basic genome biology and start with R programming, whereas a computer scientist might want to start with genome biology. After reading: You will have the basics of R and be able to dive right into specialized uses of R for computational genomics such as using Bioconductor packages. You will be familiar with statistics, supervised and unsupervised learning techniques that are important in data modeling, and exploratory analysis of high-dimensional data. You will understand genomic intervals and operations on them that are used for tasks such as aligned read counting and genomic feature annotation. You will know the basics of processing and quality checking high-throughput sequencing data. You will be able to do sequence analysis, such as calculating GC content for parts of a genome or finding transcription factor binding sites. You will know about visualization techniques used in genomics, such as heatmaps, meta-gene plots, and genomic track visualization. You will be familiar with analysis of different high-throughput sequencing data sets, such as RNA-seq, ChIP-seq, and BS-seq. You will know basic techniques for integrating and interpreting multi-omics datasets. Altuna Akalin is a group leader and head of the Bioinformatics and Omics Data Science Platform at the Berlin Institute of Medical Systems Biology, Max Delbrück Center, Berlin. He has been developing computational methods for analyzing and integrating large-scale genomics data sets since 2002. He has published an extensive body of work in this area. The framework for this book grew out of the yearly computational genomics courses he has been organizing and teaching since 2015.
Book Synopsis Clustering Stability by : Ulrike Von Luxburg
Download or read book Clustering Stability written by Ulrike Von Luxburg and published by Now Publishers Inc. This book was released on 2010 with total page 53 pages. Available in PDF, EPUB and Kindle. Book excerpt: A popular method for selecting the number of clusters is based on stability arguments: one chooses the number of clusters such that the corresponding clustering results are most stable. In recent years, a series of papers has analyzed the behavior of this method from a theoretical point of view. However, the results are very technical and difficult to interpret for non-experts. In this paper we give a high-level overview about the existing literature on clustering stability. In addition to presenting the results in a slightly informal but accessible way, we relate them to each other and discuss their different implications.
Book Synopsis Bioinformatic and Statistical Analysis of Microbiome Data by : Yinglin Xia
Download or read book Bioinformatic and Statistical Analysis of Microbiome Data written by Yinglin Xia and published by Springer Nature. This book was released on 2023-06-16 with total page 717 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique book addresses the bioinformatic and statistical modelling and also the analysis of microbiome data using cutting-edge QIIME 2 and R software. It covers core analysis topics in both bioinformatics and statistics, which provides a complete workflow for microbiome data analysis: from raw sequencing reads to community analysis and statistical hypothesis testing. It includes real-world data from the authors’ research and from the public domain, and discusses the implementation of QIIME 2 and R for data analysis step-by-step. The data as well as QIIME 2 and R computer programs are publicly available, allowing readers to replicate the model development and data analysis presented in each chapter so that these new methods can be readily applied in their own research. Bioinformatic and Statistical Analysis of Microbiome Data is an ideal book for advanced graduate students and researchers in the clinical, biomedical, agricultural, and environmental fields, as well as those studying bioinformatics, statistics, and big data analysis.
Book Synopsis Electric Vehicle Integration via Smart Charging by : Vahid Vahidinasab
Download or read book Electric Vehicle Integration via Smart Charging written by Vahid Vahidinasab and published by Springer Nature. This book was released on 2022-09-09 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book brings together important new contributions covering electric vehicle smart charging (EVSC) from a multidisciplinary group of global experts, providing a comprehensive look at EVSC and its role in meeting long-term goals for decarbonization of electricity generation and transportation. This multidisciplinary reference presents practical aspects and approaches to the technology, along with evidence from its applications to real-world energy systems. Electric Vehicle Integration via Smart Charging is suitable for practitioners and industry stakeholders working on EVSC, as well as researchers and developers from different branches of engineering, energy, transportation, economic, and operation research fields.
Book Synopsis DNA Methods in Food Safety by : Omar A. Oyarzabal
Download or read book DNA Methods in Food Safety written by Omar A. Oyarzabal and published by John Wiley & Sons. This book was released on 2014-08-21 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular typing of foodborne pathogens has become an indispensable tool in epidemiological studies. Thanks to these techniques, we now have a better understanding of the distribution and appearance of bacterial foodborne diseases and have a deeper knowledge of the type of food products associated with the major foodborne pathogens. Within the molecular techniques, DNA-based techniques have prospered for more than 40 years and have been incorporated in the first surveillance systems to monitor bacterial foodborne pathogens in the United States and other countries. However, DNA techniques vary widely and many microbiology laboratory personnel working with food and/or water face the dilemma of which method to incorporate. DNA Methods in Food Safety: Molecular Typing of Foodborne and Waterborne Bacterial Pathogens succinctly reviews more than 25 years of data on a variety of DNA typing techniques, summarizing the different mathematical models for analysis and interpretation of results, and detailing their efficacy in typing different foodborne and waterborne bacterial pathogens, such as Campylobacter, Clostridium perfringens, Listeria, Salmonella, among others. Section I describes the different DNA techniques used in the typing of bacterial foodborne pathogens, whilst Section II deals with the application of these techniques to type the most important bacterial foodborne pathogens. In Section II the emphasis is placed on the pathogen, and each chapter describes some of the most appropriate techniques for typing each bacterial pathogen. The techniques presented in this book are the most significant in the study of the molecular epidemiology of bacterial foodborne pathogens to date. It therefore provides a unique reference for students and professionals in the field of microbiology, food and water safety and epidemiology and molecular epidemiology.
Book Synopsis Precision medicine approaches for heterogeneous conditions such as autism spectrum disorders (The need for a biomarker exploration phase in clinical trials - Phase 2m) by : David Quentin Beversdorf
Download or read book Precision medicine approaches for heterogeneous conditions such as autism spectrum disorders (The need for a biomarker exploration phase in clinical trials - Phase 2m) written by David Quentin Beversdorf and published by Frontiers Media SA. This book was released on 2023-04-17 with total page 153 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many therapeutic interventions for autism spectrum disorder fail when they are examined in a clinical trial. Frequently, there is a subset of patients that responds very well to the intervention, while others do not, and the overall result does not yield a positive result. As autism spectrum disorder is highly heterogeneous in its underlying genetics and other etiological risk factors, as well as its heterogeneous phenotypic manifestation, this variability in response to any specific treatment is not entirely surprising. However, it remains a challenge to meaningfully subtype this heterogeneity for targeted treatment. The purpose of this research topic is to solicit articles that address the heterogeneity in autism spectrum disorder in a manner that may meaningfully contribute to targeted treatment approaches. Studies that address the heterogeneity of autism that could theoretically lead to targeted treatment, and studies that more directly address the use of a marker in association with response to a treatment, are both aspects that will contribute to this purpose. It is hoped that this Research Topic will yield articles that can help advance the field towards precision medicine in autism spectrum disorders. Manuscripts that contribute to the specification of the heterogeneity of autism spectrum disorder in a manner that could theoretically lead to targeted treatment would be appropriate for this research topic. Additionally, articles that utilize subtyping in relation to response to treatment would be appropriate for this research topic.
Book Synopsis Human Nutrition by : Catherine Geissler
Download or read book Human Nutrition written by Catherine Geissler and published by Oxford University Press. This book was released on 2017 with total page 785 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of human nutrition has expanded hugely in recent years, to now encompass topics as diverse as nutritional genomics and food security. As appreciation for the importance of nutrition to human health and well-being grows, an understanding of the many aspects of the subject has never been more important. Written by a renowned team of international experts, Human Nutrition provides an authoritative, comprehensive resource for students of human nutrition and other health sciences, and a valuable source of information for everybody working in nutrition and related fields. The text opens with an exploration of the chemical characteristics of foods and nutrients, before moving on to discuss the physiology of food nutrition, micronutrients, and dietary requirements for different sections of the population. The text concludes with an assessment of the evidence base for a link between nutrient intake and disease risk, and a review of the broad discipline of public health nutrition. Online Resource Centre: The Online Resource Centre to accompany Human Nutrition features: Student Resources: Auto-marked multiple choice questions to accompany each chapter Curated links to online sources of further information 'In depth' panels: extended coverage of topics included in the book Lecturer Resources: Figures from the book: available to download for use in lectures
Book Synopsis Home Cage-based Phenotyping in Rodents: Innovation, Standardization, Reproducibility and Translational Improvement by : Stefano Gaburro
Download or read book Home Cage-based Phenotyping in Rodents: Innovation, Standardization, Reproducibility and Translational Improvement written by Stefano Gaburro and published by Frontiers Media SA. This book was released on 2022-07-25 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Brain Imaging Using PET by : Michio Senda
Download or read book Brain Imaging Using PET written by Michio Senda and published by Gulf Professional Publishing. This book was released on 2002 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discusses PET technique and instrumentation, as well as developments in a range of fields such as kinetics, enzyme/neurotransmitter transport, language acquisition, and neuropathology. This title offers an analysis of brain imaging and techniques, from the foundations to the practical applications of the modern techniques used in PET.
Download or read book Can J Microbiol written by and published by . This book was released on 2012 with total page 514 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Henry's Clinical Diagnosis and Management by Laboratory Methods E-Book by : Richard A. McPherson
Download or read book Henry's Clinical Diagnosis and Management by Laboratory Methods E-Book written by Richard A. McPherson and published by Elsevier Health Sciences. This book was released on 2011-09-06 with total page 1769 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recognized as the definitive book in laboratory medicine since 1908, Henry’s Clinical Diagnosis and Management by Laboratory Methods, edited by Richard A. McPherson, MD and Matthew R. Pincus, MD, PhD, is a comprehensive, multidisciplinary pathology reference that gives you state-of-the-art guidance on lab test selection and interpretation of results. Revisions throughout keep you current on the latest topics in the field, such as biochemical markers of bone metabolism, clinical enzymology, pharmacogenomics, and more! A user-friendly full-color layout puts all the latest, most essential knowledge at your fingertips. Update your understanding of the scientific foundation and clinical application of today's complete range of laboratory tests. Get optimal test results with guidance on error detection, correction, and prevention as well as cost-effective test selection. Reference the information you need quickly and easily thanks to a full-color layout, many new color illustrations and visual aids, and an organization by organ system. Master all the latest approaches in clinical laboratory medicine with new and updated coverage of: the chemical basis for analyte assays and common interferences; lipids and dyslipoproteinemia; markers in the blood for cardiac injury evaluation and related stroke disorders; coagulation testing for antiplatelet drugs such as aspirin and clopidogrel; biochemical markers of bone metabolism; clinical enzymology; hematology and transfusion medicine; medical microbiology; body fluid analysis; and many other rapidly evolving frontiers in the field. Effectively monitor the pace of drug clearing in patients undergoing pharmacogenomic treatments with a new chapter on this groundbreaking new area. Apply the latest best practices in clinical laboratory management with special chapters on organization, work flow, quality control, interpretation of results, informatics, financial management, and establishing a molecular diagnostics laboratory. Confidently prepare for the upcoming recertification exams for clinical pathologists set to begin in 2016.
Book Synopsis Graph Embedding Methods for Multiple-Omics Data Analysis by : Chen Qingfeng
Download or read book Graph Embedding Methods for Multiple-Omics Data Analysis written by Chen Qingfeng and published by Frontiers Media SA. This book was released on 2021-11-08 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :National Academies of Sciences, Engineering, and Medicine Publisher :National Academies Press ISBN 13 :0309392020 Total Pages :133 pages Book Rating :4.3/5 (93 download)
Book Synopsis Statistical Challenges in Assessing and Fostering the Reproducibility of Scientific Results by : National Academies of Sciences, Engineering, and Medicine
Download or read book Statistical Challenges in Assessing and Fostering the Reproducibility of Scientific Results written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2016-03-29 with total page 133 pages. Available in PDF, EPUB and Kindle. Book excerpt: Questions about the reproducibility of scientific research have been raised in numerous settings and have gained visibility through several high-profile journal and popular press articles. Quantitative issues contributing to reproducibility challenges have been considered (including improper data measurement and analysis, inadequate statistical expertise, and incomplete data, among others), but there is no clear consensus on how best to approach or to minimize these problems. A lack of reproducibility of scientific results has created some distrust in scientific findings among the general public, scientists, funding agencies, and industries. While studies fail for a variety of reasons, many factors contribute to the lack of perfect reproducibility, including insufficient training in experimental design, misaligned incentives for publication and the implications for university tenure, intentional manipulation, poor data management and analysis, and inadequate instances of statistical inference. The workshop summarized in this report was designed not to address the social and experimental challenges but instead to focus on the latter issues of improper data management and analysis, inadequate statistical expertise, incomplete data, and difficulties applying sound statistic inference to the available data. Many efforts have emerged over recent years to draw attention to and improve reproducibility of scientific work. This report uniquely focuses on the statistical perspective of three issues: the extent of reproducibility, the causes of reproducibility failures, and the potential remedies for these failures.
Book Synopsis Big Data in Multimodal Medical Imaging by : Ayman El-Baz
Download or read book Big Data in Multimodal Medical Imaging written by Ayman El-Baz and published by CRC Press. This book was released on 2019-11-05 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is an urgent need to develop and integrate new statistical, mathematical, visualization, and computational models with the ability to analyze Big Data in order to retrieve useful information to aid clinicians in accurately diagnosing and treating patients. The main focus of this book is to review and summarize state-of-the-art big data and deep learning approaches to analyze and integrate multiple data types for the creation of a decision matrix to aid clinicians in the early diagnosis and identification of high risk patients for human diseases and disorders. Leading researchers will contribute original research book chapters analyzing efforts to solve these important problems.
Book Synopsis Computational methods for microbiome analysis, volume 2 by : Setubal
Download or read book Computational methods for microbiome analysis, volume 2 written by Setubal and published by Frontiers Media SA. This book was released on 2023-01-04 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt:
