Author : Daniel Adu-Ampratwum
Publisher : Thieme Chemistry
ISBN 13 : 9783131731319
Total Pages : 732 pages
Book Rating : 4.7/5 (313 download)
Book Synopsis Applications of Domino Transformations in Organic Synthesis by : Daniel Adu-Ampratwum
Download or read book Applications of Domino Transformations in Organic Synthesis written by Daniel Adu-Ampratwum and published by Thieme Chemistry. This book was released on 2016 with total page 732 pages. Available in PDF, EPUB and Kindle. Book excerpt: The rapid pace of evolution in domino, or cascade-based transformations has revolutionized the practice of chemical synthesis for the creation of natural products, designed molecules, and pharmaceuticals. "Science of Synthesis: Applications of Domino Transformations in Organic Synthesis" explores the topic thoroughly and systematically, serving as the basis for practical applications and future research. The 2-volume set presents the cutting-edge in terms of design, strategy, and experimental procedures, leading to multiple events being accomplished within a single reaction vessel. The content is organized by the core type of reaction used to initiate the event, be it a pericyclic reaction, a metal-mediated transformation, radical chemistry, or an acid-induced cascade among many others. Volume 1 covers polyene/cation-pi cyclizations, metathesis, radical, and metal-mediated reactions, and non-radical skeletal rearrangements.