Applications of Antisense Therapies to Restenosis

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Publisher : Springer Science & Business Media
ISBN 13 : 1461551838
Total Pages : 188 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Applications of Antisense Therapies to Restenosis by : LeRoy E. Rabbani

Download or read book Applications of Antisense Therapies to Restenosis written by LeRoy E. Rabbani and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: Restenosis, the proliferation of smooth muscle cells (SMC) that line blood vessels, often follows angioplasty. Despite advances in cardiology, restenosis continues to affect up to 40% of the over 500,000 patients who undergo angioplasty each year. Applications of Antisense Therapies to Restenosis is the first volume to address the potential of using antisense therapies to inhibit the restenosis that occurs after percutaneous transluminal angioplasty and coronary stenting. The work critically examines the application of various antisense therapies for inhibiting restenosis.

Gene Therapy of Cancer

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Author :
Publisher : Elsevier
ISBN 13 : 0080491367
Total Pages : 555 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Gene Therapy of Cancer by : Stanton L. Gerson

Download or read book Gene Therapy of Cancer written by Stanton L. Gerson and published by Elsevier. This book was released on 2002-04-04 with total page 555 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Second Edition of Gene Therapy of Cancer provides crucial updates on the basic science and ongoing research in this field, examining the state of the art technology in gene therapy and its therapeutic applications to the treatment of cancer. The clinical chapters are improved to include new areas of research and more successful trials. Chapters emphasize the scientific basis of gene therapy using immune, oncogene, antisense, pro-drug activating, and drug resistance gene targets, while other chapters discuss therapeutic approaches and clinical applications. This book is a valuable reference for anyone needing to stay abreast of the latest advances in gene therapy treatment for cancer. Provides in-depth description of targeted systems and treatment strategies Explains the underlying cancer biology necessary for understanding a given therapeutic approach Extensively covers immune therapeutics of vaccines, cytokines, and peptide-induced responses Presents translational focus with emphasis on requirements for clinical implementation Incorporates detailed illustrations of vectors and therapeutic approaches ideal for classroom presentations and general reference

Applications of Biotechnology in Cardiovascular Therapeutics

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Publisher : Springer Science & Business Media
ISBN 13 : 1617792403
Total Pages : 376 pages
Book Rating : 4.6/5 (177 download)

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Book Synopsis Applications of Biotechnology in Cardiovascular Therapeutics by : Kewal K. Jain

Download or read book Applications of Biotechnology in Cardiovascular Therapeutics written by Kewal K. Jain and published by Springer Science & Business Media. This book was released on 2011-07-25 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: For physicians, surgeons, and scientists working on cardiovascular disorders, Applications of Biotechnology in Cardiovascular Therapeutics serves as an invaluable reference by collecting the essential writings of Dr. Kewal K. Jain on the topics of biotechnology as they relate to cardiovascular disease. This thorough volume includes such subjects as biotechnology and therapeutic delivery to the cardiovascular system, cell-selective targeted drug delivery, cell and gene therapies, including antisense and RNA interference, cutting-edge gene therapy approaches, as well as personalized cardiology as a way of integrating new technologies into the selection of the best possible treatment for an individual patient. Selected references from recent literature are collected for each chapter, and the text is supplemented by a variety of useful tables and figures. Comprehensive and up-to-date, Applications of Biotechnology in Cardiovascular Therapeutics will be tremendously useful for those working in life sciences and the pharmaceutical sciences, and the inclusion of some basics of cardiovascular diseases will greatly benefit nonmedical readers as well.

Manual of Antisense Methodology

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Publisher : Springer Science & Business Media
ISBN 13 : 146155067X
Total Pages : 208 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Manual of Antisense Methodology by : Gunther Hartmann

Download or read book Manual of Antisense Methodology written by Gunther Hartmann and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past few years, antisense methodology has moved from in vitro studies to in vivo studies and first human trials. While the basic concept of antisense technology is simple, the methodological problems associated with its use are numerous and complex. Antisense- based methods have proven to be a field of research where careful attention to experimental protocols and appropriate controls is necessary. The Manual of Antisense Methodology emphasizes the application of antisense oligonucleotides, and is a guide for the identification of antisense and non-antisense effects in different experimental settings. The work is organized into three sections: antisense application in vitro, antisense application in vivo (animal models) and finally, clinical antisense studies. Where at all possible, the methods are described in sufficient detail to allow reproduction of a given experiment. The Manual of Antisense Methodology will be of interest to researchers in immunology, cancer research, pharmacology and internal medicine; and physicians conducting clinical studies in these fields.

Antisense Research and Application

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3642587852
Total Pages : 646 pages
Book Rating : 4.6/5 (425 download)

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Book Synopsis Antisense Research and Application by : Stanley T. Crooke

Download or read book Antisense Research and Application written by Stanley T. Crooke and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 646 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antisense technology may result in dramatic changes in the therapy of many diseases and may provide tools to dissect pharmacological processes and to confirm the roles of various genes. In this volume, progress in the understanding of antisense technology and its use in creating new drugs is discussed. Potential caveats, pitfalls and limitations of the technology are also presented. In the next few years the pace at which new molecular targets will be identified will increase exponentially as the sequencing of the human genome and of other genomes proceeds.

Interventional Cardiology Secrets

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Publisher :
ISBN 13 :
Total Pages : 404 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Interventional Cardiology Secrets by : Eduardo De Marchena

Download or read book Interventional Cardiology Secrets written by Eduardo De Marchena and published by . This book was released on 2003 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: Physicians in-training and clinicians are faced with a rapidly expanding medical literature and a shrinking amount of free time which can be devoted to the acquisition of knowledge and improvement of clinical skills. This book aims to provide a comprehensive and updated review in interventional cardiology in a Q&A format. In each chapter, authors will provide personal insights, address major controversies and how the field of interventional cardiology is likely to progress.

Combination Cancer Therapy

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Publisher : Springer Science & Business Media
ISBN 13 : 1592598641
Total Pages : 289 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Combination Cancer Therapy by : Gary K. Schwartz

Download or read book Combination Cancer Therapy written by Gary K. Schwartz and published by Springer Science & Business Media. This book was released on 2007-10-27 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: Expert physician-scientists and clinicians review those combinations of novel target agents classic chemotherapies that hold the most promise for the future of medical oncology, and detail their optimal sequence, pharmacokinetic interactions, and interaction with downstream cellular signals. The combinations run the gamut of targeted therapies against cell surface receptors (EGF-R and HER2), the cell cycle (the CDKs), signal transduction events (PKC and NF-kB), apoptosis (bcl-2), as well as focused therapies in ovarian cancer, hematologic diseases, and breast cancer. The authors emphasize novel translational approaches that are rapidly moving from the laboratory bench top to the patient's bedside for the future treatments in cancer therapy.

Antisense Drug Technology

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Publisher : CRC Press
ISBN 13 : 1439832501
Total Pages : 848 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Antisense Drug Technology by : Stanley T. Crooke

Download or read book Antisense Drug Technology written by Stanley T. Crooke and published by CRC Press. This book was released on 2007-07-25 with total page 848 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extensively revised and updated, Antisense Drug Technology: Principles, Strategies, and Applications, Second Edition reflects the logarithmic progress made in the past four years of oligonucleotide-based therapies, and, in particular, antisense therapeutics and research. Interpreting lessons learned from the clinical trials of first generati

Advanced Drug Formulation Design to Optimize Therapeutic Outcomes

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Publisher : CRC Press
ISBN 13 : 1420043889
Total Pages : 532 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Advanced Drug Formulation Design to Optimize Therapeutic Outcomes by : Robert O. Williams

Download or read book Advanced Drug Formulation Design to Optimize Therapeutic Outcomes written by Robert O. Williams and published by CRC Press. This book was released on 2007-09-25 with total page 532 pages. Available in PDF, EPUB and Kindle. Book excerpt: This title demonstrates how advanced formulation designs and delivery technologies can be used to improve drug efficacy and treatment outcomes in particular therapeutic categories or disease states. It discusses nanoparticle systems for cancer treatments, and also presents cutting edge immono-regulation agents for transplantation and the local targ

Cumulated Index Medicus

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Publisher :
ISBN 13 :
Total Pages : 1844 pages
Book Rating : 4.3/5 (243 download)

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Book Synopsis Cumulated Index Medicus by :

Download or read book Cumulated Index Medicus written by and published by . This book was released on 2000 with total page 1844 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Research Methodology and Project Management in Biotechnology

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Publisher : Bentham Science Publishers
ISBN 13 : 981508075X
Total Pages : 450 pages
Book Rating : 4.8/5 (15 download)

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Book Synopsis Research Methodology and Project Management in Biotechnology by : Simmi Kharb

Download or read book Research Methodology and Project Management in Biotechnology written by Simmi Kharb and published by Bentham Science Publishers. This book was released on 2023-12-28 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research Methodology and Project Management in Biotechnology is a vital resource addressing core concepts in the dynamic field of biotechnology. This comprehensive textbook focuses on research methodology, techniques, and project management, and provides essential knowledge for students and faculty in life sciences and allied disciplines. Key features of the book include learning objectives, self-assessments and exercises, and a simple presentation (using bullet points, tables, and figures) designed to assist comprehension and retention of key information. The book is split into 5 units with 12 focused chapters: Unit I: Molecular Biology Techniques Covers various techniques used in molecular biology, including nucleic acid isolation, DNA fragmentation, PCR, DNA sequencing, and more. Unit II: Scientific Communication and Literature Introduces the process of research writing. Unit III: Biotechnology Entrepreneurship and Marketing Covers the role of funding, intellectual property rights, and regulations. Unit IV: Genomics, Proteomics, and Bioinformatics Explores DNA sequencing strategies, gene expression analysis, and the role of bioinformatics in drug discovery. Unit V: Advanced Biotechnological Techniques Covers topics such as antisense technology, molecular cytogenetics, pharmacogenomics, next-generation DNA sequencing, and ethical considerations in science and technology. Unit VI: Medical Biotechnology Covers disease detection and diagnosis, genetic diseases, personalized medicine, nanotechnology, gene therapy, regenerative medicine, and the Human Genome Project. This textbook is suitable for courses aimed to enhance biotechnology project planning and execution skills and building a professional career path in biotechnology. Readership Students and faculty in life sciences and allied courses.

Gene and Cell Therapy

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Author :
Publisher : CRC Press
ISBN 13 : 1466572000
Total Pages : 1337 pages
Book Rating : 4.4/5 (665 download)

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Book Synopsis Gene and Cell Therapy by : Nancy Smyth Templeton

Download or read book Gene and Cell Therapy written by Nancy Smyth Templeton and published by CRC Press. This book was released on 2015-01-20 with total page 1337 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Most Comprehensive, State-of-the-Art Book on Using Gene and Cell Therapy in Clinical MedicineGene and Cell Therapy: Therapeutic Mechanisms and Strategies, Fourth Edition presents extensive background and basic information, state-of-the-art technologies, important achievements, and lingering challenges in the fields of gene and cell therapies. T

Clinical Trials of Genetic Therapy with Antisense DNA and DNA Vectors

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Author :
Publisher : CRC Press
ISBN 13 : 1000145956
Total Pages : 452 pages
Book Rating : 4.0/5 (1 download)

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Book Synopsis Clinical Trials of Genetic Therapy with Antisense DNA and DNA Vectors by : Eric Wickstrom

Download or read book Clinical Trials of Genetic Therapy with Antisense DNA and DNA Vectors written by Eric Wickstrom and published by CRC Press. This book was released on 2020-08-13 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: An important new collection of clinical and preclinical reports on genetic therapy, this book describes illustrative examples of diseases in which gene-based interventions are presently plausible, and presents case studies of current research using both synthetic oligonucleotides and biological vectors. Combining the insights of over 50 contributors, Clinical Trials of Genetic Therapy with Antisense DNA and DNA Vectors furnishes a historical overview of genetic therapy highlights official Food and Drug Administration positions on the preparation of oligonucleotides and vectors offers practical models of agent preparation, animal testing, pharmacokinetics, toxicology, and clinical trials discusses both synthetic DNA and biological vector approaches to cancer, viral, and cardiological indications illustrates for new practitioners how each stage of genetic therapy is developed details genetic treatment of leukemia; lymphoma; cancer of the brain, breast, colon, kidney, and lung; melanoma; HIV; and coronary restenosis includes examples of antisense, ribozyme, tumor suppressor, immunostimulation, and gene replacement therapy and addresses questions of preparation, delivery, toxicity, mechanism, and specificity.

Synthetic Nucleic Acids as Inhibitors of Gene Expression

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Publisher : CRC Press
ISBN 13 : 1420037897
Total Pages : 199 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Synthetic Nucleic Acids as Inhibitors of Gene Expression by : Levon Michael Khachigian

Download or read book Synthetic Nucleic Acids as Inhibitors of Gene Expression written by Levon Michael Khachigian and published by CRC Press. This book was released on 2004-11-29 with total page 199 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the post-genomic era we have, at our fingertips, an incredible array of genomic sequences from a multitude of complex organisms. There remains, however, the critical need to understand the precise roles individual genes play in complex biological milieu. Synthetic nucleic acids are at the cutting-edge of molecular strategies that target genes of

Biomedical Engineering Handbook 2

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Publisher : Springer Science & Business Media
ISBN 13 : 9783540668084
Total Pages : 1528 pages
Book Rating : 4.6/5 (68 download)

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Book Synopsis Biomedical Engineering Handbook 2 by : Joseph D. Bronzino

Download or read book Biomedical Engineering Handbook 2 written by Joseph D. Bronzino and published by Springer Science & Business Media. This book was released on 2000-02-15 with total page 1528 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cumulated Index to the Books

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Author :
Publisher :
ISBN 13 :
Total Pages : 1134 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Cumulated Index to the Books by :

Download or read book Cumulated Index to the Books written by and published by . This book was released on 1999 with total page 1134 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Review Index

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Publisher :
ISBN 13 :
Total Pages : 1520 pages
Book Rating : 4.X/5 (4 download)

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Book Synopsis Book Review Index by :

Download or read book Book Review Index written by and published by . This book was released on 2003 with total page 1520 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. 8-10 of the 1965-1984 master cumulation constitute a title index.