Antithrombotics

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Publisher : Springer Science & Business Media
ISBN 13 : 9401134847
Total Pages : 264 pages
Book Rating : 4.4/5 (11 download)

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Book Synopsis Antithrombotics by : A.G. Herman

Download or read book Antithrombotics written by A.G. Herman and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: A number of exciting new developments have occurred during the last few years concerning the platelet-vessel wall interaction. Although they may be obvious and clear to the specialist in the field, for the clinician the area has become rather confusing. Time has come to review current knowledge on the pathophysiology of the platelet-vessel wall interaction and show how this knowledge can constitute the rationale for pharmacotherapeutic interventions. A symposium was organized in Antwerp during which a number of outstanding speakers gave an overview of what is new on a particular topic and how this information can be translated to possible clinical applications. The proceedings of the symposium are not only of interest to the practising physician, but contain enough new fundamental data to be of use for all those who are interested in the role of platelets in the etiopathogenes ofcardiovascular diseases. Arnold G. Herman Antwerp, July 1-991 vii ListofContributors A.G. Herman DepartmentofPharmaceutical Sciences M.R. Buchanan University Hospital DepartmentofPathology Universiteitsplein I McMaster Clinic B-261O ANTWERP (Wilrijk) Hamilton General Hospital Belgium 237 Barton Street East HAMILTON, Ontario G. Homstra Canada L8L 2X2 DepartmentofHuman Biology UniversityofLimburg Co-author: SJ. Brister P.O. Box 616 6200MD MAASTRICHT J.-P. Cazenave The Netherlands Regional Centre ofBlood Transfusion 10, Rue Spielmann J.F. Martin F-67085 STRASBOURG Cedex Department ofMedicine France King's College School ofMedicine and Dentistry Co-authors: C. Gachet and F. Lanza LONDON SE5 9PE U.K.

Antithrombotics

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Publisher : Springer Science & Business Media
ISBN 13 : 3642599427
Total Pages : 500 pages
Book Rating : 4.6/5 (425 download)

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Book Synopsis Antithrombotics by : Andrew C.G. Uprichard

Download or read book Antithrombotics written by Andrew C.G. Uprichard and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: An up-to-date overview of blood coagulation, hemostatis, and thrombosis, this volume also provides a state-of-the-art report of current anti-thrombotic and anti-coagulant strategies as well as a summary of current research interest in the area and potential future targets. It attempts to balance traditional pharmacology with the newer sciences of molecular biology and in so doing, sets a framework for future advances in the field. The book is a concise, current and useful reference for the basic researcher as well as the practicing physician working in the fields of cardiology, internal medicine or surgery.

Gastroenterological Endoscopy

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Publisher : Georg Thieme Verlag
ISBN 13 : 3132578932
Total Pages : 1086 pages
Book Rating : 4.1/5 (325 download)

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Book Synopsis Gastroenterological Endoscopy by : Michael B. Wallace

Download or read book Gastroenterological Endoscopy written by Michael B. Wallace and published by Georg Thieme Verlag. This book was released on 2018-01-24 with total page 1086 pages. Available in PDF, EPUB and Kindle. Book excerpt: Highly Commended by the BMA Medical Book Awards for Internal Medicine! Written and edited by internationally renowned specialists, the third edition of Gastroenterological Endoscopy covers the entire spectrum of diagnostic and therapeutic procedures for the upper and lower GI tract while providing the latest overview of GI disorders. A great wealth of high-resolution photographs provides the visual information needed to confidently assess and diagnose mucosal lesions of the entire digestive tract. Significant advances in the field—both medical and technical—since the last edition are covered in comprehensive detail. Key Features: New panel of top international editors, continuing the tradition of excellence, depth, and breadth as originated by founding editors Classen, Tytgat, and Lightdale; list of contributing authors is a "who's who" of GI endoscopy Coverage of newest, advanced tools and techniques: gastric-POEMS, submucosal tunnel endoscopic resection (STER), lumen-apposing metal stents, "over-the-scope" clips, and much more More than 750 exquisite images Gastroenterological Endoscopy, third edition, surely deserves a prominent place in any complete endoscopy reference collection.

Fibrinolytic and Antithrombotic Therapy

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Publisher : Oxford University Press, USA
ISBN 13 : 0195155645
Total Pages : 421 pages
Book Rating : 4.1/5 (951 download)

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Book Synopsis Fibrinolytic and Antithrombotic Therapy by : Richard C. Becker

Download or read book Fibrinolytic and Antithrombotic Therapy written by Richard C. Becker and published by Oxford University Press, USA. This book was released on 2006 with total page 421 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thrombotic disorders of the circulatory system represent the leading cause of morbidity, motality, and health care expenditure in the United States. Fibrinolytic and Antithrombotic Therapy provides a practical, evidence-based approach to the management of thrombotic disorders for all clinicians involved in the care of patients with these disorders. It provides not only vital conceptual information on fibrinolytic and antithrombotic therapy, but also the means to apply it to everyday decision making and patient care. Focusing on managment guidelines and critical pathways, the text stresses practicality and usability. It will be a valuable resource for the wide range of clinicians involved in the care of patients with these disorders, including cardiologists, emergency physicians, primary care physicians, hematologists, neurologists, intensivists, pharmacists, and nurse practitioners. The origins of mammalian blood coagulation can be traced back over 400 million years. Despite its long history, it is only within the past century that this complex and pivotal teleologic system has begun to be understood. Most recently, the intricacies of hemostasis and pahtologic thrombosis have come to light, leading the way toward new, more effective, and safer treatment modalities. The Second Edition of Fibrinolytic and Antithrombotic Therapy, even more concise and clinically relevant than the First, provides vital, evidence-based information on management of patients with arterial and venous thrombotic disorders. Since the First Edition, the text has been expanded to cover the evolving topics of atherothrombosis, thrombocardiology, hematologic/thrombophilic conditions, and vascular medicine. It includes up-to-date guidelines for antithrombotic and fibrinolytic therapy, and offers concise summaries of current "standards of care." Chapters are dedicated to discussions of patient-specific therapeutics and to the importance of genomics, proteomics, and metabolomics in defining genotype-phenotype relationships, while throughout the book coagulation, inflammation, and vascular medicine are newly examined as elements in an intricatley-linked triad of biochemical and cellular based phenomenology.

Antithrombotic Drugs in Thrombosis Models

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Publisher : CRC Press
ISBN 13 : 1000141683
Total Pages : 248 pages
Book Rating : 4.0/5 (1 download)

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Book Synopsis Antithrombotic Drugs in Thrombosis Models by : Josef Hladovec

Download or read book Antithrombotic Drugs in Thrombosis Models written by Josef Hladovec and published by CRC Press. This book was released on 2020-11-25 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antithrombotic Drugs in Thrombosis Models presents a critical review of the use of thrombosis models and an original, highly sensitive methodology for testing antithrombotics based on a more adequate understanding of thrombotic processes. The methods form an integrated system stressing particularly the plurifactorial and global character of thrombosis and the key role of a generalized mild endothelial lesion. Packed with illustrations, this book documents the effectiveness of the system through the screening of a series of acknowledged and potential antithrombotics, and includes a unique study of their mutual combinations. Special emphasis is placed on the importance of biomodels for preliminary testing of antithrombotics. This book is particularly useful to researchers in pharmacology and the pharmaceutical industry; however, those interested in drug research and the field of cardiovascular medicine will benefit as well.

Antithrombotic Therapy

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Publisher : Professional Communications
ISBN 13 : 1932610634
Total Pages : 466 pages
Book Rating : 4.9/5 (326 download)

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Book Synopsis Antithrombotic Therapy by : Richard C. Becker

Download or read book Antithrombotic Therapy written by Richard C. Becker and published by Professional Communications. This book was released on 2010-12-31 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical application of antithrombotic therapy in both arterial disease (acute coronary syndromes, acute MI, peripheral arterial disease, valvular heart disease, atrial fibrillation) and venous disease, (venous thromboembolic disease and pulmonary embolism). Results of major clinical trials and their implications for clinical practice.

The ESC Textbook of Intensive and Acute Cardiovascular Care

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Publisher : Oxford University Press
ISBN 13 : 0192589199
Total Pages : 800 pages
Book Rating : 4.1/5 (925 download)

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Book Synopsis The ESC Textbook of Intensive and Acute Cardiovascular Care by : Marco Tubaro

Download or read book The ESC Textbook of Intensive and Acute Cardiovascular Care written by Marco Tubaro and published by Oxford University Press. This book was released on 2021-03-08 with total page 800 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ESC Textbook of Intensive and Acute Cardiovascular Care is the official textbook of the Acute Cardiovascular Care Association (ACVC) of the ESC. Cardiovascular diseases (CVDs) are a major cause of premature death worldwide and a cause of loss of disability-adjusted life years. For most types of CVD early diagnosis and intervention are independent drivers of patient outcome. Clinicians must be properly trained and centres appropriately equipped in order to deal with these critically ill cardiac patients. This new updated edition of the textbook continues to comprehensively approach all the different issues relating to intensive and acute cardiovascular care and addresses all those involved in intensive and acute cardiac care, not only cardiologists but also critical care specialists, emergency physicians and healthcare professionals. The chapters cover the various acute cardiovascular diseases that need high quality intensive treatment as well as organisational issues, cooperation among professionals, and interaction with other specialities in medicine. SECTION 1 focusses on the definition, structure, organisation and function of ICCU's, ethical issues and quality of care. SECTION 2 addresses the pre-hospital and immediate in-hospital (ED) emergency cardiac care. SECTIONS 3-5 discuss patient monitoring, diagnosis and specific procedures. Acute coronary syndromes (ACS), acute decompensated heart failure (ADHF), and serious arrhythmias form SECTIONS 6-8. The main other cardiovascular acute conditions are grouped in SECTION 9. Finally SECTION 10 is dedicated to the many concomitant acute non-cardiovascular conditions that contribute to the patients' case mix in ICCU. This edition includes new chapters such as low cardiac output states and cardiogenic shock, and pacemaker and ICDs: troubleshooting and chapters have been extensively revised. Purchasers of the print edition will also receive an access code to access the online version of the textbook which includes additional figures, tables, and videos to better to better illustrate diagnostic and therapeutic techniques and procedures in IACC. The third edition of the ESC Textbook of Intensive and Acute Cardiovascular Care will establish a common basis of knowledge and a uniform and improved quality of care across the field.

Thrombolytic and Antithrombotic Therapy for Stroke

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Publisher : CRC Press
ISBN 13 : 9781841842035
Total Pages : 280 pages
Book Rating : 4.8/5 (42 download)

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Book Synopsis Thrombolytic and Antithrombotic Therapy for Stroke by : Julian Bogousslavsky

Download or read book Thrombolytic and Antithrombotic Therapy for Stroke written by Julian Bogousslavsky and published by CRC Press. This book was released on 2006-07-07 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thrombolytic therapy for stroke with the introduction of tissue plasminogen activator (t-PA) was a boon to stroke physicians, since it meant that morbidity and mortality could be reduced with the optimal use of t-PA. The editor and his well-respected contributors offer the reader their personal perspectives on the evidence-based use of various thrombolytic and anti-thrombotic agents that are available and that can provide successful outcomes. Thrombolytic and Antithrombotic Therapy for Stroke is updated and thoroughly referenced. Everyone working in the casualty/emergency room must read this clearly-written text.

Antithrombotic Drug Therapy in Cardiovascular Disease

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Publisher : Springer Science & Business Media
ISBN 13 : 1603272356
Total Pages : 463 pages
Book Rating : 4.6/5 (32 download)

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Book Synopsis Antithrombotic Drug Therapy in Cardiovascular Disease by : Arman T. Askari

Download or read book Antithrombotic Drug Therapy in Cardiovascular Disease written by Arman T. Askari and published by Springer Science & Business Media. This book was released on 2010-03-20 with total page 463 pages. Available in PDF, EPUB and Kindle. Book excerpt: Substantial morbidity and mortality remains associated with thrombotic events has stimulated the rapid expansion of the available armamentarium to combat pathologic thrombosis. Pathologic thrombosis plays an essential role in the pathogenesis of acute coronary syndromes (ACS), ischemic complications of percutaneous coronary intervention (PCI), venous thromboembolic disease, and embolic complications of arrhythmias and various cardiomyopathies. Written by experts in the field, Antithrombotic Drug Therapy in Cardiovascular Disease carefully examines individual and various combinations of the available antithrombotic regimens including fibrinolytic agents, antiplatelet therapies (aspirin, thieneopyridines, glycoprotein IIb/IIIa inhibitors), and anticoagulant therapies (unfractionated heparin, low-molecular-weight heparins, direct thrombin inhibitors, and synthetic factor X inhibitors), non-ST-segment elevation (NSTE) ACS and ST-segment elevation myocardial infarction (STEMI). A detailed overview, Antithrombotic Drug Therapy in Cardiovascular Disease presents the evidence demonstrating the efficacy of available antithrombotic therapies in specific disease states such as atrial fibrillation, cardiomyopathy, valvular heart disease, and heparin-induced thrombocytopenia (HIT).

Harwood-Nuss' Clinical Practice of Emergency Medicine

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Publisher : Lippincott Williams & Wilkins
ISBN 13 : 0781789435
Total Pages : 1809 pages
Book Rating : 4.7/5 (817 download)

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Book Synopsis Harwood-Nuss' Clinical Practice of Emergency Medicine by : Allan B. Wolfson

Download or read book Harwood-Nuss' Clinical Practice of Emergency Medicine written by Allan B. Wolfson and published by Lippincott Williams & Wilkins. This book was released on 2009-09-15 with total page 1809 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organized for easy reference, this comprehensive, concise, and clinically focused text covers all aspects of emergency medicine. A new two-color design will help readers find critical elements of each chapter easily. A companion Web site includes the fully searchable text, more than 400 self-assessment questions with answers, and additional images and tables.

Textbook of Coronary Thrombosis and Thrombolysis

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Publisher : Springer Science & Business Media
ISBN 13 : 0792399234
Total Pages : 660 pages
Book Rating : 4.7/5 (923 download)

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Book Synopsis Textbook of Coronary Thrombosis and Thrombolysis by : R. C. Becker

Download or read book Textbook of Coronary Thrombosis and Thrombolysis written by R. C. Becker and published by Springer Science & Business Media. This book was released on 1998-01-31 with total page 660 pages. Available in PDF, EPUB and Kindle. Book excerpt: Teleologically, the hemostatic mechanism is among The of Coronary Thrombosis and the most fundamental yet complex physiologic pro- in essence, represents a heartfelt gift of cesses in humans. Early scientists and physicians were knowledge from a dedicated group of scientists and fascinated by the blood's ability to remain in a liquid clinicians, who collectively have set out on a mission state only to clot in response to vascular injury. The to minimize the societal impact of"hemostasis in the cellular and noncellular components of normal wrong place. " The book is divided into four distinct hemostasis took centuries to discover, and the intrica- sections: Part 1, Scientific Principles, lays down the cies of their delicate interactions are still being unrav- supporting foundation; Part 2, Clinical Application eled today. As is so often the case, an in-depth of Scientific Principles, places the knowledge base in appreciation of physiologic hemostasis, representing a a working perspective, directly applying science to basic life-sustaining sequence of events, paved the patient care; Part 3, New Dimensions, provides a way for understanding abnormal hemostasis or glimpse of tomorrow. Steering the field clear of se- pathologic thrombosis. Aristotle, Malpighi, and proclaimed victory and the dangers of complacency as Osier, representing but a few of the founding fathers we move into the 21st century, Part 4, Evolution of in the field, would undoubtedly be honored to see Thrombocardiology, focuses on laboratory standards, their observations form the template for lifesaving clinical trials, and drugs in development.

The Role of the Pharmacist in Patient Care

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Publisher : Universal-Publishers
ISBN 13 : 1627343083
Total Pages : 690 pages
Book Rating : 4.6/5 (273 download)

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Book Synopsis The Role of the Pharmacist in Patient Care by : Abdul Kader Mohiuddin

Download or read book The Role of the Pharmacist in Patient Care written by Abdul Kader Mohiuddin and published by Universal-Publishers. This book was released on 2020 with total page 690 pages. Available in PDF, EPUB and Kindle. Book excerpt: The goal of a high quality, cost-effective and accessible health care for patients is achieved through constructing a team-based and patient-centered health care delivery system. The expanded role of pharmacists uplifts them to patient care from dispensing and manufacturing or marketing of drugs. Along with doctors and allied health professionals, pharmacists are increasingly recognized as an integral part of the patient care team. Furthermore, colleges of pharmacy need to revise and up-date their curricula to accommodate the progressively increasing development in the pharmaceutical education and the evolving new roles of practicing pharmacists in patient care settings. This book focuses on the expanded role of the pharmacists in total patient care including prescribing, dispensing, compounding, administering and monitoring of drugs at home, hospital, community, hospice, critical care, changeover and other care settings. The sector is emerging in both developed and under-developed countries. Overburdened by patient loads and the explosion of new drugs physicians turned to pharmacists more and more for drug information especially within institutional settings. And today’s patient care pharmacists are taking more interests in medication review and reconciliation, patient education and counseling, creating drug therapy regimen and monitoring compliance. The purpose of this book is to guide the pharmacists in their daily interactions with patients and to ensure collaboration with other health professionals. The contents are mostly based on recently published articles related to patient care, with most recent ideas and activities followed by the patient care pharmacists around the globe. However, a pharmacist implements the care plan in collaboration with other health care professionals and the patient or caregiver. Along with professional guidelines, the book discusses the concepts and best practices of patient interaction, patient rights, and ethical decision-making for the professional pharmacist, apprentice and student. In every chapter, the role of pharmacists in that chapter specific issues are detailed explicitly so that a professional pharmacist or a student can figure out his or her do’s and don’ts in that specific situation. Moreover, further reading references are listed as future recommendations. So, the book is an archive of potential references too. Among so many books about patient care, either doctors’ or nurses’ roles are highlighted. The proposed book highlights the pharmacists’ roles and responsibilities to the most, separated from those of doctors and nurses, with the most recent information obtained from most publications in several journals, books, bulletins, newsletter, magazines etc.

Primary Angioplasty

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Publisher : Springer
ISBN 13 : 9811311145
Total Pages : 338 pages
Book Rating : 4.8/5 (113 download)

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Book Synopsis Primary Angioplasty by : Timothy J Watson

Download or read book Primary Angioplasty written by Timothy J Watson and published by Springer. This book was released on 2018-07-13 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is open access under a CC BY 4.0 license. This quick-reference handbook offers a concise and practical review of key aspects of the treatment of ST-segment elevation myocardial infarction (STEMI) in the era of primary percutaneous coronary intervention (PPCI). In the context of STEMI, PPCI is the preferred mode of emergency revascularization. Access to PPCI is rapidly increasing and is now routinely practiced in both general and specialist hospitals and there has been a recent emphasis on developing STEMI networks to enhance and expedite the referral pathway. This coupled with concurrent developments to enhance the safety and efficacy of the PPCI procedure has heralded an era where STEMI interventions are increasingly considered an important subspecialty within interventional cardiology. Written by leading cardiologists who have been instrumental in the adoption of PPCI in their respective institutions, the book provides junior and senior cardiologists alike with insightful and thought-provoking tips and tricks to enhance the success of PPCI procedures, which may in turn translate into direct improvements in outcomes. The book is also relevant for healthcare providers and emergency department physicians.

The Stroke Book

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Publisher : Cambridge University Press
ISBN 13 : 1107634725
Total Pages : 395 pages
Book Rating : 4.1/5 (76 download)

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Book Synopsis The Stroke Book by : Michel T. Torbey

Download or read book The Stroke Book written by Michel T. Torbey and published by Cambridge University Press. This book was released on 2013-07-18 with total page 395 pages. Available in PDF, EPUB and Kindle. Book excerpt: An essential companion for busy professionals seeking to navigate stroke-related clinical situations successfully and make quick informed treatment decisions.

The Equine Hospital Manual

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Publisher : John Wiley & Sons
ISBN 13 : 1444309374
Total Pages : 752 pages
Book Rating : 4.4/5 (443 download)

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Book Synopsis The Equine Hospital Manual by : Kevin Corley

Download or read book The Equine Hospital Manual written by Kevin Corley and published by John Wiley & Sons. This book was released on 2009-03-16 with total page 752 pages. Available in PDF, EPUB and Kindle. Book excerpt: The must-have resource drawing together all aspects of hospital care of the horse and specialist techniques in equine medicine. Written by a team of over 30 international experts working at the cutting edge of equine medicine and surgery. The emphasis is on practical, easy-to-access information, with a sound basis in evidence based medicine and full references for further enquiry. The Equine Hospital Manual covers the range of procedures used on hospitalized adult horses and foals from the simple to the advanced. The book is liberally illustrated with photographs and line drawings. Covering: Basic skills including physical examination, blood collection, and bandaging Advanced skills including mechanical ventilation, lung biopsy and cardiac output measurement Designing and setting up an equine hospital Biosecurity Therapeutic drugs used in horses and their doses Nutrition for hospital patients, including TPN and PPN Fluid therapy – choices, amounts and pitfalls Anaesthesia – equipment, techniques and post-operative care including analgesia Reflecting the substantial trend in recent years to treat horses in a hospital rather than in the field, this book provides all you need to know whether you have facilities to treat one or one hundred horses.

Encyclopedia of Gastroenterology

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Author :
Publisher : Academic Press
ISBN 13 : 012818728X
Total Pages : 3420 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Encyclopedia of Gastroenterology by :

Download or read book Encyclopedia of Gastroenterology written by and published by Academic Press. This book was released on 2019-11-06 with total page 3420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Encyclopedia of Gastroenterology, Second Edition provides a comprehensive and concise reference on all aspects of gastroenterology and hepatology, including the organs in the gastrointestinal system, their functions in health and disease, and strategies or procedures to resolve or prevent problems and disease. This concise, up-to-date information includes comprehensive sections on the impact of nutrition, gastrointestinal microbiota, lifestyle, commonly used drugs, and surgical procedures on health and disease. Since the first edition, attention to the roles of nutrition and gastrointestinal microorganisms (microbiota, formerly Microbiota) in health and disease has skyrocketed. In addition, an entirely new section on obesity and diabetes is included. Presents comprehensive coverage of every topic within gastroenterology Offers researchers a one-stop, fully-referenced resource to explore questions Includes teaching tools, multimedia and interactive elements Provides readers with multi-layered content and a media-rich learning resource for both instructors and students Covers hot new topics in GI health and disease, including new sections on stem cells, intestinal bacteria, obesity and intestinal microbiota

Contemporary Drug Synthesis

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Publisher : John Wiley & Sons
ISBN 13 : 0471686735
Total Pages : 238 pages
Book Rating : 4.4/5 (716 download)

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Book Synopsis Contemporary Drug Synthesis by : Jie Jack Li

Download or read book Contemporary Drug Synthesis written by Jie Jack Li and published by John Wiley & Sons. This book was released on 2004-12-27 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: An integrated and insightful look at successful drug synthesis in today's drug discovery market The pharmaceutical industry is unquestionably vibrant today, with drug synthesis making a vital contribution. Whether in the early developmental stages of identifying and optimizing a lead, or the latter stages of process development and cost-effective scale-up, the ability to design elegant and economical synthetic routes is often a major factor in the eventual viability and commercial success of a drug. Contemporary Drug Synthesis examines how leading researchers and manufacturers have integrated chemistry, biology, pharmacokinetics, and a host of other disciplines in the creation and development of leading drugs. Authored by four of the pharmaceutical industry's most respected scientists, this timely volume: Focuses on the processes that resulted in high-profile drugs including Lipitor, Celebrex, Viagra, Gleevec, Nexium, Claritin, and over a dozen others Provides an in-depth introduction to each drug, followed by a detailed account of its synthesis Organizes the drugs into fourteen therapeutic areas for clarity and ease of use Process chemists provide an essential bridge between chemistry and the marketplace, creating scientifically practical drug processes while never losing sight of the commercial viability of those processes. Contemporary Drug Synthesis meets the needs of a growing community of researchers in pharmaceutical research and development, and is both a useful guide for practicing pharmaceutical scientists and an excellent text for medicinal and organic chemistry students.