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Download or read book Antisense Technology Part B written by and published by . This book was released on 2000 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher : Elsevier
ISBN 13 : 0080496717
Total Pages : 683 pages
Book Rating : 4.0/5 (84 download)
Download or read book Antisense Technology, Part B: Applications written by and published by Elsevier. This book was released on 1999-11-10 with total page 683 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antisense technology is the ability to manipulate gene expression within mammalian cells providing powerful experimental approaches for the study of gene function and gene regulation. For example, methods which inhibit gene expression permit studies probing the normal function of a specific product within a cell. Such methodology can be used in many disciplines such as pharmacology, oncology, genetics, cell biology, developmental biology, molecular biology, biochemistry, and neurosciences. This volume will be a truly important tool in biomedically-oriented research.The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today-truly an essential publication for researchers in all fields of life sciences.
Author : Stanley T. Crooke
Publisher : CRC Press
ISBN 13 : 1439832501
Total Pages : 848 pages
Book Rating : 4.4/5 (398 download)
Download or read book Antisense Drug Technology written by Stanley T. Crooke and published by CRC Press. This book was released on 2007-07-25 with total page 848 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extensively revised and updated, Antisense Drug Technology: Principles, Strategies, and Applications, Second Edition reflects the logarithmic progress made in the past four years of oligonucleotide-based therapies, and, in particular, antisense therapeutics and research. Interpreting lessons learned from the clinical trials of first generati
Author : Conrad Lichtenstein
Publisher : IRL Press
ISBN 13 : 9780199635832
Total Pages : 334 pages
Book Rating : 4.6/5 (358 download)
Download or read book Antisense Technology written by Conrad Lichtenstein and published by IRL Press. This book was released on 1997 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antisense technology is a powerful procedure that permits the controlled silencing of a specific gene for investigations of mRNA and protein function. This valuable text provides proven step-by-step protocols for antisense techniques in a range of different organisms and cell culture systems. In addition it discusses the potential benefits and problems for various antisense methods which complement gene knock-out experiments. The book includes antisense techniques such as: analysis of nucleic acid structures; measurement and evaluation of antisense effects; selection, preparation and the use of antisense oligonucleotides; in vitro RNA transcription; construction strategies, testing and optimization of catalytic antisense RNAs based on hammerhead ribozymes; synthesis and evaluation of 2-5 A- antisense chimeras for targeted degradation of RNA. The application of these technologies are then described, with chapters on antisense techniques in IDictyostelium, plants and the medical uses and benefits of antisense sense technology both in vitro and in vivo. Finally, non-antisense effects of oligonucleotides, "anti-sense rescue", shotgun antisense mutagenesis, and in vivo, in vitro and in situ detection of sense: antisense duplexes by structure-specific anti-RNA antibodies are discussed. The numerous hints and tips for success and advice on trouble shooting, make this authoritative text invaluable to all those researchers who work on gene expression, RNA transcription, or protein function.
Download or read book Antisense technology written by and published by . This book was released on 1993 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Stanley T. Crooke
Publisher : Springer Science & Business Media
ISBN 13 : 3642587852
Total Pages : 646 pages
Book Rating : 4.6/5 (425 download)
Download or read book Antisense Research and Application written by Stanley T. Crooke and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 646 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antisense technology may result in dramatic changes in the therapy of many diseases and may provide tools to dissect pharmacological processes and to confirm the roles of various genes. In this volume, progress in the understanding of antisense technology and its use in creating new drugs is discussed. Potential caveats, pitfalls and limitations of the technology are also presented. In the next few years the pace at which new molecular targets will be identified will increase exponentially as the sequencing of the human genome and of other genomes proceeds.
Author : Cy A. Stein
Publisher : Wiley-Liss
ISBN 13 :
Total Pages : 556 pages
Book Rating : 4.3/5 (91 download)
Download or read book Applied Antisense Oligonucleotide Technology written by Cy A. Stein and published by Wiley-Liss. This book was released on 1998-03-19 with total page 556 pages. Available in PDF, EPUB and Kindle. Book excerpt: Applied Antisense Oligonucleotide Technology provides the basic concepts as well as the practical concerns associated with the use of antisense oligonucleotides to modify gene expression. Chapters include oligonucleotide chemistry, DNA triplex formation, delivery mechanisms, pharmocokinetics, toxicity, oligonucleotides.
Author :
Publisher : Academic Press
ISBN 13 : 9780121822149
Total Pages : 0 pages
Book Rating : 4.8/5 (221 download)
Download or read book Antisense Technology, Part A, General Methods, Methods of Delivery, and RNA Studies written by and published by Academic Press. This book was released on 1999-10-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antisense technology is the ability to manipulate gene expression within mammalian cells providing powerful experimental approaches for the study of gene function and gene regulation. For example, methods that inhibit gene expression permit studies which probe the normal function of a specific product within a cell. Such methodology can be used in many disciplines such as pharmacology, oncology, genetics, cell biology, developmental biology, molecular biology, biochemistry, and neurosciences. This volume will be a truly important tool in biomedical-oriented research. The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.
Author :
Publisher : Elsevier
ISBN 13 : 0080496709
Total Pages : 614 pages
Book Rating : 4.0/5 (84 download)
Download or read book Antisense Technology, Part A, General Methods, Methods of Delivery, and RNA Studies written by and published by Elsevier. This book was released on 1999-11-01 with total page 614 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antisense technology is the ability to manipulate gene expression within mammalian cells providing powerful experimental approaches for the study of gene function and gene regulation. For example, methods that inhibit gene expression permit studies which probe the normal function of a specific product within a cell. Such methodology can be used in many disciplines such as pharmacology, oncology, genetics, cell biology, developmental biology, molecular biology, biochemistry, and neurosciences. This volume will be a truly important tool in biomedical-oriented research.The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.
Author : M. Ian Phillips
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (428 download)
Download or read book Antisense Technology: Applications written by M. Ian Phillips and published by . This book was released on 2000 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Phillips, I M
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (648 download)
Download or read book Antisense Technology written by Phillips, I M and published by . This book was released on 1999 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : R. Schlingensiepen
Publisher : Wiley-Blackwell
ISBN 13 : 9780865426696
Total Pages : 365 pages
Book Rating : 4.4/5 (266 download)
Download or read book Antisense-From Technology to Therapy: Lab Manual and Textbook written by R. Schlingensiepen and published by Wiley-Blackwell. This book was released on 1997-03-21 with total page 365 pages. Available in PDF, EPUB and Kindle. Book excerpt: The target specific inhibition of gene-expression using antisense nucleic acids has developed into a key technology in molecular biology, bio-medical research and an entirely new field of pharmacotherapy. Like the first conference in 1993, the Second International Conference on Antisense Nucleic Acids will provide a forum for basic researchers, clinicians focusing on the application of antisense techniques in physiological settings and disease states. Major topics are Drug Delivery Systems, Pharmacology Targeting of sites of pathology and reports on the first clinical trials in virology and hematology.
Author : Phillips, I M
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (714 download)
Download or read book Antisense Technology written by Phillips, I M and published by . This book was released on 2000 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Reimar Schlingensiepen
Publisher :
ISBN 13 : 9783894122393
Total Pages : 365 pages
Book Rating : 4.1/5 (223 download)
Download or read book Antisense. From Technology to Therapy. written by Reimar Schlingensiepen and published by . This book was released on 1997-12 with total page 365 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Olof Gissberg
Publisher : Humana
ISBN 13 : 9781493996728
Total Pages : 344 pages
Book Rating : 4.9/5 (967 download)
Download or read book Oligonucleotide-Based Therapies written by Olof Gissberg and published by Humana. This book was released on 2020-08-15 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a collection of comprehensive, up-to-date, and broadly applicable guides to the research and development fields of oligonucleotide (ON) therapeutics. Covering topics from the study of antisense and anti-gene effects to oligonucleotides in the context of drug discovery and development, the volume explores a wide-ranging and useful spectrum of methods and protocols needed to take full advantage of therapeutic applications involving ONs. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Oligonucleotide-Based Therapies: Methods and Protocols aims to be a great aid in the laboratory as well as an ideal reference guide when designing antisense and anti-gene oligonucleotides for therapeutic applications.
Author : Akira Murakami
Publisher : Springer
ISBN 13 : 364230463X
Total Pages : 189 pages
Book Rating : 4.6/5 (423 download)
Download or read book Nucleic Acid Drugs written by Akira Murakami and published by Springer. This book was released on 2012-07-04 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt: New Antisense Strategies: Chemical Synthesis of RNA Oligomers, by Junichi Yano und Gerald E. Smyth Development and Modification of Decoy Oligodeoxynucleotides for Clinical Application, by Mariana Kiomy Osako, Hironori Nakagami und Ryuichi Morishita Modulation of Endosomal Toll-Like Receptor-Mediated Immune Responses by Synthetic Oligonucleotides, by Ekambar R. Kandimalla und Sudhir Agrawal Delivery of Nucleic Acid Drugs, by Yan Lee und Kazunori Kataoka Aptamer: Biology to Applications, by Yoshikazu Nakamura Development and Clinical Applications of Nucleic Acid Therapeutics, by Veenu Aishwarya, Anna Kalota und Alan M. Gewirtz
Author : Jens Kurreck
Publisher : Royal Society of Chemistry
ISBN 13 : 0854041168
Total Pages : 362 pages
Book Rating : 4.8/5 (54 download)
Download or read book Therapeutic Oligonucleotides written by Jens Kurreck and published by Royal Society of Chemistry. This book was released on 2008 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a compelling overall update on current status of RNA interference
