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Anticonvulsant Screening Project
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Author :National Institute of Neurological and Communicative Disorders and Stroke (U.S.). Epilepsy Branch Publisher : ISBN 13 : Total Pages :20 pages Book Rating :4.F/5 ( download)
Book Synopsis Anticonvulsant Screening Project by : National Institute of Neurological and Communicative Disorders and Stroke (U.S.). Epilepsy Branch
Download or read book Anticonvulsant Screening Project written by National Institute of Neurological and Communicative Disorders and Stroke (U.S.). Epilepsy Branch and published by . This book was released on 1976 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :National Institute of Neurological and Communicative Disorders and Stroke. Epilepsy Branch Publisher : ISBN 13 : Total Pages :20 pages Book Rating :4.3/5 (121 download)
Book Synopsis Anticonvulsant Screening Project by : National Institute of Neurological and Communicative Disorders and Stroke. Epilepsy Branch
Download or read book Anticonvulsant Screening Project written by National Institute of Neurological and Communicative Disorders and Stroke. Epilepsy Branch and published by . This book was released on 1976 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Molecular and Cellular Targets for Anti-epileptic Drugs by : G. Avanzini
Download or read book Molecular and Cellular Targets for Anti-epileptic Drugs written by G. Avanzini and published by John Libbey Eurotext. This book was released on 1997 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: A new phase of anti-epileptic drugs (AEDs) investigation has begun in which new drugs can be designed to target specific epileptogenic mechanisms. A rational approach to therapy today requires not only a full awareness of phamacokinetics of AEDs but also a thorough knowledge of their molecular targets and of their influence on excitatory and inhibitory mechanisms in the brain. This book provides a multi-author systematic look at this subject, from neurobiological bases to clinical applications. It includes four sections dealing with fundamental aspects of cortical excitability, models of epileptic disorders, targets for anti-epileptic drugs and rational approaches to therapy. Each chapter provides a review of a specific topic prepared by well known scientists active in the field, introducing their most recent results in a concise and comprehensive form.
Book Synopsis Antiepileptic Drugs by : René H. Levy
Download or read book Antiepileptic Drugs written by René H. Levy and published by Lippincott Williams & Wilkins. This book was released on 2002 with total page 1000 pages. Available in PDF, EPUB and Kindle. Book excerpt: The thoroughly revised, updated Fifth Edition of this classic is the m ost comprehensive, current, and authoritative reference on all anticon vulsants available today. This edition features detailed profiles of n ewer drugs--including levetiracetam, oxcarbazepine, tiagabine, topiram ate, and zonisamide--and new chapters on use of antiepileptic drugs in children and during pregnancy. Drugs are covered in alphabetical ord er and in an easy-to-follow format: mechanisms of action; chemistry, b iotransformation, and pharmacokinetics; interactions; clinical efficac y and use; and adverse effects. Coverage of clinical use includes none pileptic and psychiatric disorders where appropriate. This edition has been trimmed to manageable size by shortening chapters on older, less frequently used drugs.
Download or read book DHEW Publication written by and published by . This book was released on 19?? with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Models of Seizures and Epilepsy by : Asla Pitkänen
Download or read book Models of Seizures and Epilepsy written by Asla Pitkänen and published by Elsevier. This book was released on 2005-10-04 with total page 705 pages. Available in PDF, EPUB and Kindle. Book excerpt: An understanding of mechanisms underlying seizure disorders depends critically on the insights provided by model systems. In particular with the development of cellular, molecular, and genetic investigative tools, there has been an explosion of basic epilepsy research. Models of Seizures and Epilepsy brings together, for the first time in 30 years, an overview of the most widely-used models of seizures and epilepsy. Chapters cover a broad range of experimental approaches (from in vitro to whole animal preparations), a variety of epileptiform phenomenology (including burst discharges and seizures), and suggestions for model characterization and validation, such as electrographic, morphologic, pharmacologic, and behavioral features. Experts in the field provide not only technical reviews of these models but also conceptual critiques - commenting on the strengths and limitations of these models, their relationship to clinical phenomenology, and their value in developing a better understanding and treatments. Models of Seizures and Epilepsy is a valuable, practical reference for investigators who are searching for the most appropriate laboratory models for addressing key questions in the field. It also provides an important background for physicians, fellows, and students, offering insight into the potential for advances in epilepsy research. - The first comprehensive description of animal models of epilepsy since the early 1970's - Comprehensive analysis of "What the models model" to guide the selection of each model, and what specific questions it will answer - Elegant examples of the use of novel technologies that can be applied in experimental epilepsy research - World expert opinions on the clinical relevance of each model
Book Synopsis Current Catalog by : National Library of Medicine (U.S.)
Download or read book Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on 1980 with total page 1340 pages. Available in PDF, EPUB and Kindle. Book excerpt: First multi-year cumulation covers six years: 1965-70.
Book Synopsis Publication Catalog of the U.S. Department of Health and Human Services by : United States. Department of Health and Human Services
Download or read book Publication Catalog of the U.S. Department of Health and Human Services written by United States. Department of Health and Human Services and published by . This book was released on with total page 596 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Antiepileptic Drug Development written by and published by . This book was released on 1978 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Catalog of Publications by : United States. Department of Health, Education, and Welfare
Download or read book Catalog of Publications written by United States. Department of Health, Education, and Welfare and published by . This book was released on 1978 with total page 596 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Treatment of Epilepsy by : Simon Shorvon
Download or read book The Treatment of Epilepsy written by Simon Shorvon and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 948 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, there have been rapid advances both in medical and surgical treatments of epilepsy. This book provides a comprehensive textbook on medical and surgical treatment of epilepsy, and acts as a clinical reference book with a strong practical bias.
Author :National Institute of Neurological and Communicative Disorders and Stroke Publisher : ISBN 13 : Total Pages :16 pages Book Rating :4.3/5 ( download)
Book Synopsis The NINCDS Epilepsy Research Program by : National Institute of Neurological and Communicative Disorders and Stroke
Download or read book The NINCDS Epilepsy Research Program written by National Institute of Neurological and Communicative Disorders and Stroke and published by . This book was released on 1978 with total page 16 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies Publisher : ISBN 13 : Total Pages :2470 pages Book Rating :4.:/5 (319 download)
Book Synopsis Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 2008 by : United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies
Download or read book Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 2008 written by United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies and published by . This book was released on 2007 with total page 2470 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Publication Catalog of the U.S. Department of Health, Education, and Welfare by : United States. Department of Health, Education, and Welfare
Download or read book Publication Catalog of the U.S. Department of Health, Education, and Welfare written by United States. Department of Health, Education, and Welfare and published by . This book was released on 1978 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Neuropharmacology Methods in Epilepsy Research by : Steven L. Peterson
Download or read book Neuropharmacology Methods in Epilepsy Research written by Steven L. Peterson and published by CRC Press. This book was released on 2019-05-07 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is an estimated 2.5 million epileptics in the US and perhaps some 40 million worldwide. As research has become increasingly molecular in scope, fewer scientists are trained in the US on basic, integrated epilepsy techniques. One frustration in neuroscience today is the application of state-of-the-art molecular biology techniques to inappropriate animal models of epilepsy - frequently resulting in inconclusive results. Epilepsy research will be increasingly undertaken by scientists well-trained in reductionist methodology, but who may be unfamiliar with integrated, whole-animal techniques. This situation appears even more difficult considering there has been no updated textbook on experimental models of epilepsy over the last twenty years - until now. Neuropharmacology Methods in Epilepsy Research describes fundamental methodologies and procedures in this field, representing the only detailed text concerning experimental models of epilepsy published in the last 20 years. This guide studies the reproduction of well-characterized and readily interpretable experimental models of epilepsy to which state-of-the-art molecular biology techniques can be applied. Each chapter features: Introduction - providing a brief background and historical account of the techniques and their use Methodology - describing equipment, solutions, species, electrodes as well as considering variations of techniques and stimulation parameters Interpretations - demonstrating the relevance of techniques to epilepsy as well as describing what exactly is being studied and how the data is appropriately applied to understanding epilepsy Topics include electroshock, chemoconvulsions, kindling, audiogenic seizures, focal seizures, and brain slice preparations. Discussions also include: Recently developed seizure models, including status epilepticus and massed trial simulations Influence of circadian and diurnal rhythms on convulsive activity Behavior al and cognitive deficits associated with anticonvulsant drug testing Technical approaches, i.e. slice models, microdialysis techniques, intracranial implant surgery, audiogenic seizure testing, kindling paradigms, and the rhythmic nature of seizures This unique text provides a thorough reference for the diverse methodologies within this area of neuropharmacological research - providing the basis for on-going cellular and molecular investigations as well as novel therapeutic approaches to the treatment of epilepsy.
Download or read book Antiepileptic Drugs written by M.J. Eadie and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 658 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1985, volume 74 of the Springer-Verlag Handbook of Experimental Phar macology, under the editorship of H. -H. Frey and D. Janz, appeared. In this volume the then available data on the topic of antiepileptic drugs were col lated and analysed. Over the intervening years knowledge in this area has grown progressively. More new antiepileptic drugs than the total number of agents that were in common use 15 years ago have in the interval either come on to the market or are about to do so. As well, further agents are at a fairly advanced stage of development, whilst the already established drugs have by and large held their places in clinical practice. Knowledge of epileptogenesis has advanced considerably. The mechanisms of action of antiepileptic drugs at the molecular level and in various animal models of epileptic seizures and of the epileptic state are much better understood than they were previously. As well, more information is available concerning the natural history of human epilepsy, and this knowledge is important in making optimal use of the various agents that are now available. Therefore, it has seemed appropriate at this stage in the evolution of knowledge to produce a second volume dealing with Antiepileptic Drugs in the Handbook of Experimental Pharmacology series.
Book Synopsis NIH Guide for Grants and Contracts by : National Institutes of Health (U.S.)
Download or read book NIH Guide for Grants and Contracts written by National Institutes of Health (U.S.) and published by . This book was released on with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt:
