Anthracycline Chemistry and Biology I

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Publisher : Springer
ISBN 13 : 3540758151
Total Pages : 333 pages
Book Rating : 4.5/5 (47 download)

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Book Synopsis Anthracycline Chemistry and Biology I by : Karsten Krohn

Download or read book Anthracycline Chemistry and Biology I written by Karsten Krohn and published by Springer. This book was released on 2009-10-29 with total page 333 pages. Available in PDF, EPUB and Kindle. Book excerpt: With contributions by numerous experts

Anthracycline Chemistry and Biology II

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Publisher : Springer Science & Business Media
ISBN 13 : 3540758127
Total Pages : 231 pages
Book Rating : 4.5/5 (47 download)

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Book Synopsis Anthracycline Chemistry and Biology II by : Karsten Krohn

Download or read book Anthracycline Chemistry and Biology II written by Karsten Krohn and published by Springer Science & Business Media. This book was released on 2008-07-11 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt: This series presents critical reviews of the present position and future trends in modern chemical research. It contains short and concise reports on chemistry, each written by the world renowned experts. The series is still valid and useful after five or ten years. More information as well as the electronic version of the whole content is available at: springerlink.com.

Medicinal Chemistry of Anticancer Drugs

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Publisher : Elsevier
ISBN 13 : 0444626670
Total Pages : 767 pages
Book Rating : 4.4/5 (446 download)

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Book Synopsis Medicinal Chemistry of Anticancer Drugs by : Carmen Avendaño

Download or read book Medicinal Chemistry of Anticancer Drugs written by Carmen Avendaño and published by Elsevier. This book was released on 2015-06-11 with total page 767 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medicinal Chemistry of Anticancer Drugs, Second Edition, provides an updated treatment from the point of view of medicinal chemistry and drug design, focusing on the mechanism of action of antitumor drugs from the molecular level, and on the relationship between chemical structure and chemical and biochemical reactivity of antitumor agents. Antitumor chemotherapy is a very active field of research, and a huge amount of information on the topic is generated every year. Cytotoxic chemotherapy is gradually being supplemented by a new generation of drugs that recognize specific targets on the surface or inside cancer cells, and resistance to antitumor drugs continues to be investigated. While these therapies are in their infancy, they hold promise of more effective therapies with fewer side effects. Although many books are available that deal with clinical aspects of cancer chemotherapy, this book provides a sorely needed update from the point of view of medicinal chemistry and drug design. - Presents information in a clear and concise way using a large number of figures - Historical background provides insights on how the process of drug discovery in the anticancer field has evolved - Extensive references to primary literature

Advances in Precision Medicine Oncology

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Author :
Publisher : BoD – Books on Demand
ISBN 13 : 183968867X
Total Pages : 262 pages
Book Rating : 4.8/5 (396 download)

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Book Synopsis Advances in Precision Medicine Oncology by : Hilal Arnouk

Download or read book Advances in Precision Medicine Oncology written by Hilal Arnouk and published by BoD – Books on Demand. This book was released on 2021-07-21 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent advances in precision medicine and immuno-oncology have led to highly specific and efficacious cancer therapies such as monoclonal antibodies and immune checkpoint inhibitors (ICIs). This book provides an up-to-date overview of advances in the field of immuno-oncology. Chapters cover such topics as ICIs and how they mount a robust immune response against cancer cells as well as the response of ICIs to treatment predictive biomarkers and their potential immune-related adverse events (irAEs). Additionally, the book includes a comprehensive review of the powerful FDA-approved therapeutic agent doxorubicin, highlighting the molecular mechanisms behind doxorubicin’s drug resistance and critical side effects.

Burger's Medicinal Chemistry, Drug Discovery and Development, 8 Volume Set

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 111953030X
Total Pages : 6057 pages
Book Rating : 4.1/5 (195 download)

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Book Synopsis Burger's Medicinal Chemistry, Drug Discovery and Development, 8 Volume Set by :

Download or read book Burger's Medicinal Chemistry, Drug Discovery and Development, 8 Volume Set written by and published by John Wiley & Sons. This book was released on 2021-04-20 with total page 6057 pages. Available in PDF, EPUB and Kindle. Book excerpt: Burger’s Medicinal Chemistry, Drug Discovery and Development Explore the freshly updated flagship reference for medicinal chemists and pharmaceutical professionals The newly revised eighth edition of the eight-volume Burger’s Medicinal Chemistry, Drug Discovery and Development is the latest installment in this celebrated series covering the entirety of the drug development and discovery process. With the addition of expert editors in each subject area, this eight-volume set adds 35 chapters to the extensive existing chapters. New additions include analyses of opioid addiction treatments, antibody and gene therapy for cancer, blood-brain barrier, HIV treatments, and industrial-academic collaboration structures. Along with the incorporation of practical material on drug hunting, the set features sections on drug discovery, drug development, cardiovascular diseases, metabolic diseases, immunology, cancer, anti-Infectives, and CNS disorders. The text continues the legacy of previous volumes in the series by providing recognized, renowned, authoritative, and comprehensive information in the area of drug discovery and development while adding cutting-edge new material on issues like the use of artificial intelligence in medicinal chemistry. Included: Volume 1: Methods in Drug Discovery, edited by Kent D. Stewart Volume 2: Discovering Lead Molecules, edited by Kent D. Stewart Volume 3: Drug Development, edited by Ramnarayan S. Randad and Michael Myers Volume 4: Cardiovascular, Endocrine, and Metabolic Diseases, edited by Scott D. Edmondson Volume 5: Pulmonary, Bone, Immunology, Vitamins, and Autocoid Therapeutic Agents, edited by Bryan H. Norman Volume 6: Cancer, edited by Barry Gold and Donna M. Huryn Volume 7: Anti-Infectives, edited by Roland E. Dolle Volume 8: CNS Disorders, edited by Richard A. Glennon Perfect for research departments in the pharmaceutical and biotechnology industries, Burger’s Medicinal Chemistry, Drug Discovery and Development can be used by graduate students seeking a one-stop reference for drug development and discovery and deserves its place in the libraries of biomedical research institutes, medical, pharmaceutical, and veterinary schools.

Orbitals in Chemistry

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Publisher : Springer Science & Business Media
ISBN 13 : 3642017509
Total Pages : 328 pages
Book Rating : 4.6/5 (42 download)

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Book Synopsis Orbitals in Chemistry by : Satoshi Inagaki

Download or read book Orbitals in Chemistry written by Satoshi Inagaki and published by Springer Science & Business Media. This book was released on 2009-12-16 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: See Table of Contents (PMP)

STM and AFM Studies on (Bio)molecular Systems: Unravelling the Nanoworld

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Publisher : Springer Science & Business Media
ISBN 13 : 3540783954
Total Pages : 326 pages
Book Rating : 4.5/5 (47 download)

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Book Synopsis STM and AFM Studies on (Bio)molecular Systems: Unravelling the Nanoworld by : Paolo Samori

Download or read book STM and AFM Studies on (Bio)molecular Systems: Unravelling the Nanoworld written by Paolo Samori and published by Springer Science & Business Media. This book was released on 2009-11-04 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: Still valid and useful after a decade, this work presents critical reviews of the present position and future trends in modern chemical research. It contains short and concise reports on chemistry, each written by world-renowned experts.

Templates in Chemistry III

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Publisher : Springer
ISBN 13 : 3540896929
Total Pages : 269 pages
Book Rating : 4.5/5 (48 download)

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Book Synopsis Templates in Chemistry III by : Peter Broekmann

Download or read book Templates in Chemistry III written by Peter Broekmann and published by Springer. This book was released on 2009-11-06 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 1 intends to shed light on a selection of aspects of "template chemistry" by combining chapters from areas as different as templated solid state synthesis, metal-mediated self assembly processes, organometallic synthesis, the formation of mechanically interlocked molecules, and, last but not least, the production of inorganic materials based on organic templates such as gels. Volume 2 provides an even broader overview of and deeper insight into the template topic adding new aspects and new views.

The Organic Chemistry of Drug Design and Drug Action

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Publisher : Elsevier
ISBN 13 : 0080513379
Total Pages : 650 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis The Organic Chemistry of Drug Design and Drug Action by : Richard B. Silverman

Download or read book The Organic Chemistry of Drug Design and Drug Action written by Richard B. Silverman and published by Elsevier. This book was released on 2012-12-02 with total page 650 pages. Available in PDF, EPUB and Kindle. Book excerpt: Standard medicinal chemistry courses and texts are organized by classes of drugs with an emphasis on descriptions of their biological and pharmacological effects. This book represents a new approach based on physical organic chemical principles and reaction mechanisms that allow the reader to extrapolate to many related classes of drug molecules. The Second Edition reflects the significant changes in the drug industry over the past decade, and includes chapter problems and other elements that make the book more useful for course instruction. - New edition includes new chapter problems and exercises to help students learn, plus extensive references and illustrations - Clearly presents an organic chemist's perspective of how drugs are designed and function, incorporating the extensive changes in the drug industry over the past ten years - Well-respected author has published over 200 articles, earned 21 patents, and invented a drug that is under consideration for commercialization

Anticancer Agents from Natural Products, Second Edition

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Author :
Publisher : CRC Press
ISBN 13 : 1439813825
Total Pages : 786 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Anticancer Agents from Natural Products, Second Edition by : Gordon M. Cragg

Download or read book Anticancer Agents from Natural Products, Second Edition written by Gordon M. Cragg and published by CRC Press. This book was released on 2011-10-10 with total page 786 pages. Available in PDF, EPUB and Kindle. Book excerpt: The approach to drug discovery from natural sources has yielded many important new pharmaceuticals inaccessible by other routes. In many cases the isolated natural product may not be an effective drug for any of several reasons, but it nevertheless may become a drug through chemical modification or have a novel pharmacophore for future drug design. In summarizing the status of natural products as cancer chemotherapeutics, Anticancer Agents from Natural Products, Second Edition covers the: History of each covered drug—a discussion of its mechanism on action, medicinal chemistry, synthesis, and clinical applications Potential for novel drug discovery through the use of genome mining as well as future developments in anticancer drug discovery Important biosynthetic approaches to "unnatural" natural products Anticancer Agents from Natural Products, Second Edition discusses how complex target-oriented synthesis—enabled by historic advances in methodology—has enormously expanded the scope of the possible. This book covers the current clinically used anticancer agents that are either natural products or are clearly derived from natural product leads. It also reviews drug candidates currently in clinical development since many of these will be clinically used drugs in the future. Examples include the drugs etoposide and teniposide derived from the lead compound podophyllotoxin; numerous analogs derived from taxol; topotecan, derived from camptothecin; and the synthetic clinical candidates, E7389 and HTI-286, developed from the marine leads, halichondrin B and hemiasterlin.

Advances in Precision Medicine Oncology

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Publisher :
ISBN 13 : 9781839688690
Total Pages : 0 pages
Book Rating : 4.6/5 (886 download)

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Book Synopsis Advances in Precision Medicine Oncology by : Hilal Arnouk

Download or read book Advances in Precision Medicine Oncology written by Hilal Arnouk and published by . This book was released on 2021 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent advances in precision medicine and immuno-oncology have led to highly specific and efficacious cancer therapies such as monoclonal antibodies and immune checkpoint inhibitors (ICIs). This book provides an up-to-date overview of advances in the field of immuno-oncology. Chapters cover such topics as ICIs and how they mount a robust immune response against cancer cells as well as the response of ICIs to treatment predictive biomarkers and their potential immune-related adverse events (irAEs). Additionally, the book includes a comprehensive review of the powerful FDA-approved therapeutic agent doxorubicin, highlighting the molecular mechanisms behind doxorubicin's drug resistance and critical side effects.

Functional Metal-Organic Frameworks: Gas Storage, Separation and Catalysis

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3642146120
Total Pages : 270 pages
Book Rating : 4.6/5 (421 download)

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Book Synopsis Functional Metal-Organic Frameworks: Gas Storage, Separation and Catalysis by : Martin Schröder

Download or read book Functional Metal-Organic Frameworks: Gas Storage, Separation and Catalysis written by Martin Schröder and published by Springer Science & Business Media. This book was released on 2010-09-07 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: - Microporous Organic Polymers: Design, Synthesis, and Function By J.-X. Jiang and A. I. Cooper - Hydrogen, Methane and Carbon Dioxide Adsorption in Metal-Organic Framework Materials By X. Lin, N. R. Champness, and M. Schröder -Doping of Metal-Organic Frameworks with Functional Guest Molecules and Nanoparticles By F. Schröder and R. A. Fischer -Chiral Metal-Organic Porous Materials: Synthetic Strategies and Applications in Chiral Separation and Catalysis By K. Kim, M. Banerjee, M. Yoon, and S. Das -Controlled Polymerization by Incarceration of Monomers in Nanochannels By T. Uemura and S. Kitagawa -Designing Metal-Organic Frameworks for Catalytic Applications L. Ma and W. Lin -Magnetic and Porous Molecule-Based Materials By N. Roques, V. Mugnaini, and J. Veciana

Anticancer Treatments and Cardiotoxicity

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Publisher : Academic Press
ISBN 13 : 0128026472
Total Pages : 483 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Anticancer Treatments and Cardiotoxicity by : Patrizio Lancellotti

Download or read book Anticancer Treatments and Cardiotoxicity written by Patrizio Lancellotti and published by Academic Press. This book was released on 2016-11-11 with total page 483 pages. Available in PDF, EPUB and Kindle. Book excerpt: Anticancer Treatments and Cardiotoxicity: Mechanisms, Diagnostic and Therapeutic Interventions presents cutting edge research on the adverse cardiac effects of both radiotherapy and chemotherapy, brought together by leaders in the field. Cancer treatment-related cardiotoxicity is the leading cause of treatment-associated mortality in cancer survivors and is one of the most common post-treatment issues among survivors of adult cancer. Early detection of the patients prone to developing cardiotoxicity, taking in to account the type of treatment, history and other risk factors, is essential in the fight to decrease cardiotoxic mortality. This illustrated reference describes the most effective diagnostic and imaging tools to evaluate and predict the development of cardiac dysfunction for those patients undergoing cancer treatment. In addition, new guidelines on imaging for the screening and monitoring of these patients are also presented. Anticancer Treatments and Cardiotoxicity is an essential reference for those involved in the research and treatment of cardiovascular toxicity. - Provides algorithms essential for the use of imaging, and biomarkers for the screening and monitoring of patients - Written by world-leading experts in the field of cardiotoxicity - Includes high-quality images, case studies, and test questions - Describes the most effective diagnostic and imaging tools to evaluate and predict the development of cardiac dysfunction for those patients undergoing cancer treatment

Inorganic and Organometallic Transition Metal Complexes with Biological Molecules and Living Cells

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Publisher : Academic Press
ISBN 13 : 012803887X
Total Pages : 408 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Inorganic and Organometallic Transition Metal Complexes with Biological Molecules and Living Cells by : Kenneth Kam-Wing Lo

Download or read book Inorganic and Organometallic Transition Metal Complexes with Biological Molecules and Living Cells written by Kenneth Kam-Wing Lo and published by Academic Press. This book was released on 2016-12-30 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inorganic and Organometallic Transition Metal Complexes with Biological Molecules and Living Cells provides a complete overview of this important research area that is perfect for both newcomers and expert researchers in the field. Through concise chapters written and edited by esteemed experts, this book brings together a comprehensive treatment of the area previously only available through scattered, lengthy review articles in the literature. Advanced topics of research are covered, with particular focus on recent advances in the biological applications of transition metal complexes, including inorganic medicine, enzyme inhibitors, antiparasital agents, and biological imaging reagents. - Geared toward researchers and students who seek an introductory overview of the field, as well as researchers working in advanced areas - Focuses on the interactions of inorganic and organometallic transition metal complexes with biological molecules and live cells - Foscuses on the fundamentals and their potential therapeutic and diagnostic applications - Covers recent biological applications of transition metal complexes, such as anticancer drugs, enzyme inhibitors, bioconjugation agents, chemical biology tools, and bioimaging reagents

Luminescence Applied in Sensor Science

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Publisher : Springer Science & Business Media
ISBN 13 : 3642194192
Total Pages : 234 pages
Book Rating : 4.6/5 (421 download)

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Book Synopsis Luminescence Applied in Sensor Science by : Luca Prodi

Download or read book Luminescence Applied in Sensor Science written by Luca Prodi and published by Springer Science & Business Media. This book was released on 2011-04-28 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Logic Gates and Luminescent Sensors Based on Photoinduced Electron Transfer, by A. Prasanna de Silva and S. Uchiyama; Luminescent Chemical Sensing, Biosensing, and Screening Using Upconverting Nanoparticles, by D. E. Achatz, R. Ali, and O. S. Wolfbeis; Luminescence Amplification Strategies Integrated with Microparticle and Nanoparticle Platforms, by S. Zhu, T. Fischer, W. Wan, A. B. Descalzo, and K. Rurack; Luminescent Chemosensors Based on Silica Nanoparticles, by S. Bonacchi, D. Genovese, R. Juris, M. Montalti, L. Prodi, E. Rampazzo, M. Sgarzi, and N. Zaccheroni; Fluorescence Based Sensor Arrays, by R. Paolesse, D. Monti, F. Dini, and C. Di Natale; Enantioselective Sensing by Luminescence, by A. Accetta, R. Corradini, and R. Marchelli

Carbohydrates in Sustainable Development I

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Author :
Publisher : Springer
ISBN 13 : 3642148379
Total Pages : 212 pages
Book Rating : 4.6/5 (421 download)

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Book Synopsis Carbohydrates in Sustainable Development I by : Amélia P. Rauter

Download or read book Carbohydrates in Sustainable Development I written by Amélia P. Rauter and published by Springer. This book was released on 2010-09-28 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sucrose: A Prospering and Sustainable Organic Raw Material,By S. Peters, T. Rose, and M. Moser; Sucrose-Utilizing Transglucosidases for Biocatalysis, By I. André, G. Potocki-Véronèse, S. Morel, P. Monsan, and M. Remaud-Siméon; Difructose Dianhydrides DFAs) and DFA-Enriched Products as Functional Foods, By C. Ortiz Mellet and J. M. García Fernández; Development of Agriculture Left-Overs: Fine Organic Chemicals from Wheat Hemicellulose-Derived Pentoses, By F. Martel, B. Estrine, R. Plantier-Royon, N. Hoffmann, and C. Portella; Cellulose and Derivatives from Wood and Fibers as Renewable Sources of Raw-Materials, By J.A. Figueiredo, M.I. Ismael, C.M.S. Anjo, and A.P. Duarte; Olive Pomace, a Source for Valuable Arabinan-Rich Pectic Polysaccharides,By M. A. Coimbra, S. M. Cardoso, and J. A. Lopes-da-Silva; Oligomannuronates from Seaweeds as Renewable Sources for the Development of Green Surfactants,By T. Benvegnu and J.-F. Sassi; From Natural Polysaccharides to Materials for Catalysis, Adsorption, and Remediation, By F. Quignard, F. Di Renzo, and E. Guibal

Carbohydrates in Sustainable Development I

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3642148360
Total Pages : 212 pages
Book Rating : 4.6/5 (421 download)

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Book Synopsis Carbohydrates in Sustainable Development I by : Amélia P. Rauter

Download or read book Carbohydrates in Sustainable Development I written by Amélia P. Rauter and published by Springer Science & Business Media. This book was released on 2010-09-20 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sucrose: A Prospering and Sustainable Organic Raw Material,By S. Peters, T. Rose, and M. Moser; Sucrose-Utilizing Transglucosidases for Biocatalysis, By I. André, G. Potocki-Véronèse, S. Morel, P. Monsan, and M. Remaud-Siméon; Difructose Dianhydrides DFAs) and DFA-Enriched Products as Functional Foods, By C. Ortiz Mellet and J. M. García Fernández; Development of Agriculture Left-Overs: Fine Organic Chemicals from Wheat Hemicellulose-Derived Pentoses, By F. Martel, B. Estrine, R. Plantier-Royon, N. Hoffmann, and C. Portella; Cellulose and Derivatives from Wood and Fibers as Renewable Sources of Raw-Materials, By J.A. Figueiredo, M.I. Ismael, C.M.S. Anjo, and A.P. Duarte; Olive Pomace, a Source for Valuable Arabinan-Rich Pectic Polysaccharides,By M. A. Coimbra, S. M. Cardoso, and J. A. Lopes-da-Silva; Oligomannuronates from Seaweeds as Renewable Sources for the Development of Green Surfactants,By T. Benvegnu and J.-F. Sassi; From Natural Polysaccharides to Materials for Catalysis, Adsorption, and Remediation, By F. Quignard, F. Di Renzo, and E. Guibal