Anionic Annulations in Organic Synthesis

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Publisher : Elsevier
ISBN 13 : 0128138017
Total Pages : 466 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Anionic Annulations in Organic Synthesis by : Dipakranjan Mal

Download or read book Anionic Annulations in Organic Synthesis written by Dipakranjan Mal and published by Elsevier. This book was released on 2018-10-25 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: Anionic Annulations in Organic Synthesis: A Versatile and Prolific Class of Ring-Forming Reactions is a comprehensive review of the main annulations for the construction of cyclic structures and their use in the total synthesis of functional molecules. The book explores in detail the Hauser, Robinson, Sammes, and Myers annulations, all of which are beneficial to constructing substrates with complex molecular structures suitable for pharmaceutical purposes. This volume begins with an in-depth introduction on the history and perspectives of annulations. It then covers different categories of annulation in each chapter, examining their application to drug synthesis for a range of different medicinal compounds. Anionic Annulations in Organic Synthesis delivers a thorough analysis of the topic and provides the tools necessary to master anionic organic chemistry. It is a valuable resource for chemists, researchers, and students seeking a complete and detailed understanding of anionic annulations. - Serves as a useful tool to both academic and industrial researchers in the field - Includes numerous examples of anionic annulations and how to apply them practically in research and industry - Features anionic annulations that are particularly effective for the synthesis of polyoxygenated polycyclic compounds

Organic Reactions, Volume 107

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Publisher : John Wiley & Sons
ISBN 13 : 1119771285
Total Pages : 1172 pages
Book Rating : 4.1/5 (197 download)

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Book Synopsis Organic Reactions, Volume 107 by :

Download or read book Organic Reactions, Volume 107 written by and published by John Wiley & Sons. This book was released on 2021-08-25 with total page 1172 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 107th volume in this series for organic chemists in academia and industry presents critical discussions of the following widely used organic reactions: ENANTIOSELECTIVE HYDROFORMYLATION Toshiki Tazawa, Andreas Phanopoulos, and Kyoko Nozaki HAUSER KRAUS, SAMMES, STAUNTON WEINREB, AND TAMURA ANNULATIONS Charles B. de Koning, Kathy Hadje Georgiou, Joseph P. Michael, and Amanda L. Rousseau

Lewis Base Catalysis in Organic Synthesis

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Publisher : John Wiley & Sons
ISBN 13 : 3527675175
Total Pages : 1488 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Lewis Base Catalysis in Organic Synthesis by : Edwin Vedejs

Download or read book Lewis Base Catalysis in Organic Synthesis written by Edwin Vedejs and published by John Wiley & Sons. This book was released on 2016-08-03 with total page 1488 pages. Available in PDF, EPUB and Kindle. Book excerpt: This three-volume set represents the first comprehensive coverage of the rapidly expanding field of Lewis base catalysis that has attracted enormous attention in recent years. Lewis base catalysis is a conceptually novel paradigm that encompasses an extremely wide variety of preparatively useful transformations and is particularly effective for enantioselectively constructing new stereogenic centers. As electron-pair donors, Lewis bases can influence the rate and stereochemical course of myriad synthetic organic reactions. The book presents the conceptual/mechanistic principles that underlie Lewis base catalysis, and then builds upon that foundation with a thorough presentation of many different reaction types. And last but not least, the editors, Prof. Edwin Vedejs and Prof. Scott E. Denmark, are without doubt the leaders in this emerging field and have compiled high quality contributions from an impressive collection of international experts.

Lewis Base Catalysis in Organic Synthesis, 3 Volume Set

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Publisher : John Wiley & Sons
ISBN 13 : 3527336184
Total Pages : 1476 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Lewis Base Catalysis in Organic Synthesis, 3 Volume Set by : Edwin Vedejs

Download or read book Lewis Base Catalysis in Organic Synthesis, 3 Volume Set written by Edwin Vedejs and published by John Wiley & Sons. This book was released on 2016-10-10 with total page 1476 pages. Available in PDF, EPUB and Kindle. Book excerpt: This three-volume set represents the first comprehensive coverage of the rapidly expanding field of Lewis base catalysis that has attracted enormous attention in recent years. Lewis base catalysis is a conceptually novel paradigm that encompasses an extremely wide variety of preparatively useful transformations and is particularly effective for enantioselectively constructing new stereogenic centers. As electron-pair donors, Lewis bases can influence the rate and stereochemical course of myriad synthetic organic reactions. The book presents the conceptual/mechanistic principles that underlie Lewis base catalysis, and then builds upon that foundation with a thorough presentation of many different reaction types. And last but not least, the editors, Prof. Edwin Vedejs and Prof. Scott E. Denmark, are without doubt the leaders in this emerging field and have compiled high quality contributions from an impressive collection of international experts.

Organic Synthesis Using Transition Metals

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Publisher : John Wiley & Sons
ISBN 13 : 1119978947
Total Pages : 469 pages
Book Rating : 4.1/5 (199 download)

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Book Synopsis Organic Synthesis Using Transition Metals by : Roderick Bates

Download or read book Organic Synthesis Using Transition Metals written by Roderick Bates and published by John Wiley & Sons. This book was released on 2012-04-30 with total page 469 pages. Available in PDF, EPUB and Kindle. Book excerpt: Transition metals open up new opportunities for synthesis, because their means of bonding and their reaction mechanisms differ from those of the elements of the s and p blocks. In the last two decades the subject has mushroomed - established reactions are seeing both technical improvements and increasing numbers of applications, and new reactions are being developed. The practicality of the subject is demonstrated by the large number of publications coming from the process development laboratories of pharmaceutical companies, and its importance is underlined by the fact that three Nobel prizes have been awarded for discoveries in this field in the 21st Century already. Organic Synthesis Using Transition Metals, 2nd Edition considers the ways in which transition metals, as catalysts and reagents, can be used in organic synthesis, both for pharmaceutical compounds and for natural products. It concentrates on the bond-forming reactions that set transition metal chemistry apart from "classical" organic chemistry. Each chapter is extensively referenced and provides a convenient point of entry to the research literature. Topics covered include: introduction to transition metals in organic synthesis coupling reactions C-H activation carbonylative coupling reactions alkene and alkyne insertion reactions electrophilic alkene and alkyne complexes reactions of alkyne complexes carbene complexes h3- or p-allyl -allyl complexes diene, dienyl and arene complexes cycloaddition and cycloisomerisation reactions For this second edition the text has been extensively revised and expanded to reflect the significant improvements and advances in the field since the first edition, as well as the large number of new transition metal-catalysed processes that have come to prominence in the last 10 years – for example the extraordinary progress in coupling reactions using “designer” ligands, catalysis using gold complexes, new opportunities arising from metathesis chemistry, and C-H activation – without neglecting the well established chemistry of metals such as palladium. Organic Synthesis Using Transition Metals, 2nd Edition will find a place on the bookshelves of advanced undergraduates and postgraduates working in organic synthesis, catalysis, medicinal chemistry and drug discovery. It is also useful for practising researchers who want to refresh and enhance their knowledge of the field.

Essential Reagents for Organic Synthesis

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Publisher : John Wiley & Sons
ISBN 13 : 1119279836
Total Pages : 640 pages
Book Rating : 4.1/5 (192 download)

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Book Synopsis Essential Reagents for Organic Synthesis by : Philip L. Fuchs

Download or read book Essential Reagents for Organic Synthesis written by Philip L. Fuchs and published by John Wiley & Sons. This book was released on 2016-07-19 with total page 640 pages. Available in PDF, EPUB and Kindle. Book excerpt: From Boron Trifluoride to Zinc, the 52 most widely used reagents in organic synthesis are described in this unique desktop reference for every organic chemist. The list of reagents contains classics such as N-Bromosuccinimide (NBS) and Trifluoromethanesulfonic Acid side by side with recently developed ones like Pinacolborane and Tetra-n-propylammonium Perruthenate (TPAP). For each reagent, a concise article provides a brief description of all important reactions for which the reagent is being used, including yields and reaction conditions, an overview of the physical properties of the reagent, its storage conditions, safe handling, laboratory synthesis and purification methods. Advantages and disadvantages of the reagent compared to alternative synthesis methods are also discussed. Reagents have been hand-picked from among the 5000 reagents contained in EROS, the Encyclopedia of Reagents for Organic Synthesis. Every organic chemist should be familiar with these key reagents that can make almost every reaction work.

Domino Reactions in Organic Synthesis

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Publisher : John Wiley & Sons
ISBN 13 : 3527608680
Total Pages : 631 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Domino Reactions in Organic Synthesis by : Lutz F. Tietze

Download or read book Domino Reactions in Organic Synthesis written by Lutz F. Tietze and published by John Wiley & Sons. This book was released on 2006-12-13 with total page 631 pages. Available in PDF, EPUB and Kindle. Book excerpt: Domino reactions enable you to build complex structures in one-pot reactions without the need to isolate intermediates- a dream comes true. In this book, the well-respected expert, Professor Lutz Tietze, summarizes the possibilities of this reaction type - an approach for an efficiant, economically benificial and ecological benign synthesis. A definite must for every organic chemist.

Reagents for Silicon-Mediated Organic Synthesis

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Publisher : John Wiley & Sons
ISBN 13 : 1118636139
Total Pages : 816 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Reagents for Silicon-Mediated Organic Synthesis by : Philip L. Fuchs

Download or read book Reagents for Silicon-Mediated Organic Synthesis written by Philip L. Fuchs and published by John Wiley & Sons. This book was released on 2013-05-30 with total page 816 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the last three decades the importance of organosiliconchemistry has greatly increased because it has opened a number ofnew synthetic strategies. Silicon reagents are usually low-cost,versatile and allow a wide range of reactions. This is the firstHandbook to compile essential Silicon containing reagents and makesuse of the leading reagent database e-EROS. Another hotvolume in the series Handbooks of Reagents for OrganicSynthesis, this is a must-have resource for all syntheticchemists working in drug development and medicinal chemistry. For the selection the Editor focussed on three key syntheticapproaches with the greatest impact: 1. Use of silicon as a 'temporary tether' by unifying a reactivepair of functional groups and taking advantage of theirtemplate-biased intramolecular cyclization. 2. The specific use of the silane functionality as a heterot-butyl group, often colloquially referred to as the use ofsilicon as a 'fat proton'. 3. The use of the Brook rearrangement as an 'anion relaystratagem'. A new feature in this Handbook is the reagent finder, analphabetically organized lookup table arranged by organicfunctionality and specific structure of the silicon atom to whichit is bound.

Alkynes in Cycloadditions

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Publisher : John Wiley & Sons
ISBN 13 : 1118709292
Total Pages : 357 pages
Book Rating : 4.1/5 (187 download)

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Book Synopsis Alkynes in Cycloadditions by : Irina A. Maretina

Download or read book Alkynes in Cycloadditions written by Irina A. Maretina and published by John Wiley & Sons. This book was released on 2013-10-08 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt: Acetylene systems present a new route to cyclic compounds as an alternative to more traditional methods employed in classical organic chemistry. The synthesis of cyclic structures based on acetylene systems has important applications in the formation of nanostructures, naturally occurring compounds and chemosensory materials for the design of nonlinear optics, electronic and photonic devices. Alkynes in Cycloadditions presents a modern review of regioselective synthesis of aromatic and non-aromatic carbocyclic and heterocyclic ring systems based primarily on [2+2+2] and [4+2] cycloadditions, and other reactions of acetylenic units including enediynes and enyne-allenes. Topics covered include: New strategies for the formation of aromatic and polynuclear hydrocarbons based on (Z)-hex-3-en-1,5-diyne and (Z)-hepta-1,2,4-triene-6-yne blocks. One-step synthesis of benzene derivatives, β-substituted naphthalenes and acenes by the cycloaromatization of enediynes and enyne-allenes by Bergman, Myers-Saito and Shmittel. Mechanisms of cycloaromatization resulting in the formation of fulvene and indene systems. Heterocyclization involving enyne-carbodiimides. New achievements in classical cycloaddition reactions such as the Diels-Alder condensation with acetylenic dienophiles and [2+2] cycloadditions with acetylene components Alkynes in Cycloadditions presents a comprehensive summary of the literature on methods for the synthesis of ring systems from acetylenes for academic researchers working in the fields of organic synthesis, physical organic chemistry, organometallic chemistry, catalysis, materials science, nanomaterials and biochemistry.

Strategies and Tactics in Organic Synthesis

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Publisher : Elsevier Inc. Chapters
ISBN 13 : 0128056134
Total Pages : 25 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Strategies and Tactics in Organic Synthesis by : Jenny B. Werness

Download or read book Strategies and Tactics in Organic Synthesis written by Jenny B. Werness and published by Elsevier Inc. Chapters. This book was released on 2013-07-29 with total page 25 pages. Available in PDF, EPUB and Kindle. Book excerpt: Addition of halogen and nucleophiles to conjugated 1,3-enynes in a 1,4-fashion produces a chiral allene and a stereogenic center. The diastereo- and enantioselectivity of this process are discussed in detail. The 1,4-bromoetherification of 1,3-enynes can be applied to the synthesis of various bromoallene-containing natural products. Our diastereo- and enantioselective total synthesis of kumausallene is described in this chapter. The synthesis features a cascade reaction involving palladium-catalyzed desymmetrization and a DMF-mediated diastereoselective 1,4-bromoetherification reaction.

Organic Chemistry

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Publisher : John Wiley & Sons
ISBN 13 : 3527819274
Total Pages : 2876 pages
Book Rating : 4.5/5 (278 download)

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Book Synopsis Organic Chemistry by : Pierre Vogel

Download or read book Organic Chemistry written by Pierre Vogel and published by John Wiley & Sons. This book was released on 2019-08-08 with total page 2876 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides the background, tools, and models required to understand organic synthesis and plan chemical reactions more efficiently Knowledge of physical chemistry is essential for achieving successful chemical reactions in organic chemistry. Chemists must be competent in a range of areas to understand organic synthesis. Organic Chemistry provides the methods, models, and tools necessary to fully comprehend organic reactions. Written by two internationally recognized experts in the field, this much-needed textbook fills a gap in current literature on physical organic chemistry. Rigorous yet straightforward chapters first examine chemical equilibria, thermodynamics, reaction rates and mechanisms, and molecular orbital theory, providing readers with a strong foundation in physical organic chemistry. Subsequent chapters demonstrate various reactions involving organic, organometallic, and biochemical reactants and catalysts. Throughout the text, numerous questions and exercises, over 800 in total, help readers strengthen their comprehension of the subject and highlight key points of learning. The companion Organic Chemistry Workbook contains complete references and answers to every question in this text. A much-needed resource for students and working chemists alike, this text: -Presents models that establish if a reaction is possible, estimate how long it will take, and determine its properties -Describes reactions with broad practical value in synthesis and biology, such as C-C-coupling reactions, pericyclic reactions, and catalytic reactions -Enables readers to plan chemical reactions more efficiently -Features clear illustrations, figures, and tables -With a Foreword by Nobel Prize Laureate Robert H. Grubbs Organic Chemistry: Theory, Reactivity, and Mechanisms in Modern Synthesis is an ideal textbook for students and instructors of chemistry, and a valuable work of reference for organic chemists, physical chemists, and chemical engineers.

Fiesers' Reagents for Organic Synthesis, Volume 24

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Publisher : John Wiley & Sons
ISBN 13 : 0470225548
Total Pages : 549 pages
Book Rating : 4.4/5 (72 download)

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Book Synopsis Fiesers' Reagents for Organic Synthesis, Volume 24 by : Tse-Lok Ho

Download or read book Fiesers' Reagents for Organic Synthesis, Volume 24 written by Tse-Lok Ho and published by John Wiley & Sons. This book was released on 2008-09-22 with total page 549 pages. Available in PDF, EPUB and Kindle. Book excerpt: From reviews of previous volumes: "Essential for chemistry collections at the university and research levels." -New York Public Library "Highly recommended . . . lots of succinct, practical information on recent developments . . . in a format that is easy to use. The reagents are taken up in alphabetical order (common usage names, not CAS indexing codenames), sometimes several to a page, sometimes several pages to a reagent. One can expect to find how to make the reagent (in loose terms), or where it can be bought, what it is good for, and where to seek complete details. As with previous volumes, one can profit from just browsing, even if one does not feel a need to look up any particular subject. It is thus a secondary function of the book to help one keep abreast of the field, and it would be a rare chemist who would not learn something new and useful from a casual perusal of the pages." -Journal of the American Chemical Society This highly successful series has provided generations of professional chemists with a comprehensive, up-to-date look at the reagent literature. Now the series continues with its concise descriptions, good structural formulas, and selected examples of application, providing references to new reagents as well as to reagents included in previous volumes. This volume covers the synthetic literature from 2005 to 2006. CONTENTS: General abbreviations Reference abbreviations Reagents Author index Subject index

Comprehensive Organic Synthesis

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Publisher :
ISBN 13 : 9780080359298
Total Pages : pages
Book Rating : 4.3/5 (592 download)

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Book Synopsis Comprehensive Organic Synthesis by :

Download or read book Comprehensive Organic Synthesis written by and published by . This book was released on 1991 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

A Short History of Chemistry

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Publisher :
ISBN 13 :
Total Pages : 596 pages
Book Rating : 4.2/5 (986 download)

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Book Synopsis A Short History of Chemistry by : James Riddick Partington

Download or read book A Short History of Chemistry written by James Riddick Partington and published by . This book was released on 1951 with total page 596 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Molecular Rearrangements in Organic Synthesis

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Publisher : John Wiley & Sons
ISBN 13 : 111834796X
Total Pages : 774 pages
Book Rating : 4.1/5 (183 download)

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Book Synopsis Molecular Rearrangements in Organic Synthesis by : Christian M. Rojas

Download or read book Molecular Rearrangements in Organic Synthesis written by Christian M. Rojas and published by John Wiley & Sons. This book was released on 2015-10-26 with total page 774 pages. Available in PDF, EPUB and Kindle. Book excerpt: Designed for practitioners of organic synthesis, this book helps chemists understand and take advantage of rearrangement reactions to enhance the synthesis of useful chemical compounds. Provides ready access to the genesis, mechanisms, and synthetic utility of rearrangement reactions Emphasizes strategic synthetic planning and implementation Covers 20 different rearrangement reactions Includes applications for synthesizing compounds useful as natural products, medicinal compounds, functional materials, and physical organic chemistry

Small Ring Compounds in Organic Synthesis IV

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Publisher : Springer
ISBN 13 : 9783662150146
Total Pages : 160 pages
Book Rating : 4.1/5 (51 download)

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Book Synopsis Small Ring Compounds in Organic Synthesis IV by : Armin de Meijere

Download or read book Small Ring Compounds in Organic Synthesis IV written by Armin de Meijere and published by Springer. This book was released on 2014-03-12 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Handbook of Reagents for Organic Synthesis

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Publisher : John Wiley & Sons
ISBN 13 : 111872657X
Total Pages : 826 pages
Book Rating : 4.1/5 (187 download)

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Book Synopsis Handbook of Reagents for Organic Synthesis by : André B. Charette

Download or read book Handbook of Reagents for Organic Synthesis written by André B. Charette and published by John Wiley & Sons. This book was released on 2015-07-15 with total page 826 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heteroarenes are among the most prevalent structural units in natural products, pharmaceuticals, agrochemicals, and other compounds of scientific or commercial interest. In the last decade, a broad range of novel synthetic methods has been developed to not only facilitate construction of the heteroarene motif, but to enable its modification through direct C H functionalization. This Handbook describes 117 key reagents for selective heteroarene functionalization reactions, including both traditional and transition metal-catalyzed C H functionalization. Since these reactions typically involve one heteroarene, a coupling partner and a catalyst, the handbook not only focuses on the catalyst itself but also contains other key reaction species. All the information compiled in this volume is also available in electronic format on Wiley Online Library. The 117 reagents represented here are but a small fraction of the ca. 5,000 reagents available in the electronic Encyclopedia of Reagents for Organic Synthesis (e-EROS). e-EROS offers various search interfaces to locate reagents of interest, including chemical structure, substructure and reactions search modes. e-EROS is updated regularly with new and updated entries.