Animal Models For Stem Cell Therapy

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Animal Models for Stem Cell Therapy

Author : Bruno Christ
Publisher : Humana
ISBN 13 : 9781493948130
Total Pages : 0 pages
Book Rating : 4.9/5 (481 download)

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Book Synopsis Animal Models for Stem Cell Therapy by : Bruno Christ

Download or read book Animal Models for Stem Cell Therapy written by Bruno Christ and published by Humana. This book was released on 2016-09-17 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Animal Models for Stem Cell Therapy: Methods and Protocols, expert researchers in the field detail disease models of hepatic, cardiovascular, neurological diseases, connective and contractile tissue. Chapters focus on a wide range of diseases and application of different kinds of stem cells and reprogrammed tissue cells (iPS). Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Animal Models for Stem Cell Therapy: Methods and Protocols, covers interest of basic scientists and clinicians to assess the biological as well as the therapeutic potential of stem cell therapy.

Regenerative Therapy Using Blood-Derived Stem Cells

Author : David S. Allan
Publisher : Springer Science & Business Media
ISBN 13 : 9781617794711
Total Pages : 220 pages
Book Rating : 4.7/5 (947 download)

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Book Synopsis Regenerative Therapy Using Blood-Derived Stem Cells by : David S. Allan

Download or read book Regenerative Therapy Using Blood-Derived Stem Cells written by David S. Allan and published by Springer Science & Business Media. This book was released on 2011-11-16 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: Blood has long been viewed as a conduit for therapy, stemming from the ancient days of phlebotomy to remove evil humors to the development of successful blood transfusions to replace missing blood components. The identification and characterization of hematopoietic stem cells by Drs. Till and McCulloch revolutionized the field and soon after, non-hematopoietic stem and progenitor cells were characterized from the blood and bone marrow. Some of these cell types and various blood-derived cell lineages are involved in the repair of various types of tissue damage that span the spectrum of medical disorders. The goal of this book is to provide an up-to-date review of the various types of blood-derived cells with regenerative capacity, identify opportunities for intervention by examining specific clinical applications, and recognize the regulatory environment that will encompass future therapies in regenerative medicine.

Stem Cell and Gene-Based Therapy

Author : Alexander Battler
Publisher : Springer Science & Business Media
ISBN 13 : 9781846286766
Total Pages : 460 pages
Book Rating : 4.2/5 (867 download)

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Book Synopsis Stem Cell and Gene-Based Therapy by : Alexander Battler

Download or read book Stem Cell and Gene-Based Therapy written by Alexander Battler and published by Springer Science & Business Media. This book was released on 2007-06-26 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: Regenerative medicine – stem cell and gene-based therapy – offers a new approach for restoring function of damaged organs and tissues. This is the first book to cover the major new aspects and field of regenerative medicine. This title is therefore a timely addition to the literature. It brings together the major approaches to regenerative medicine in one text, which ensures that techniques learnt in one discipline are disseminated across other areas of medicine.

Stem Cells and the Future of Regenerative Medicine

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309170427
Total Pages : 112 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Stem Cells and the Future of Regenerative Medicine by : Institute of Medicine

Download or read book Stem Cells and the Future of Regenerative Medicine written by Institute of Medicine and published by National Academies Press. This book was released on 2002-01-25 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent scientific breakthroughs, celebrity patient advocates, and conflicting religious beliefs have come together to bring the state of stem cell researchâ€"specifically embryonic stem cell researchâ€"into the political crosshairs. President Bush's watershed policy statement allows federal funding for embryonic stem cell research but only on a limited number of stem cell lines. Millions of Americans could be affected by the continuing political debate among policymakers and the public. Stem Cells and the Future of Regenerative Medicine provides a deeper exploration of the biological, ethical, and funding questions prompted by the therapeutic potential of undifferentiated human cells. In terms accessible to lay readers, the book summarizes what we know about adult and embryonic stem cells and discusses how to go about the transition from mouse studies to research that has therapeutic implications for people. Perhaps most important, Stem Cells and the Future of Regenerative Medicine also provides an overview of the moral and ethical problems that arise from the use of embryonic stem cells. This timely book compares the impact of public and private research funding and discusses approaches to appropriate research oversight. Based on the insights of leading scientists, ethicists, and other authorities, the book offers authoritative recommendations regarding the use of existing stem cell lines versus new lines in research, the important role of the federal government in this field of research, and other fundamental issues.

Hematopoietic Stem Cells

Author : Christa Müller-Sieburg
Publisher : Springer
ISBN 13 :
Total Pages : 278 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Hematopoietic Stem Cells by : Christa Müller-Sieburg

Download or read book Hematopoietic Stem Cells written by Christa Müller-Sieburg and published by Springer. This book was released on 1992 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Regenerative Medicine and Cell Therapy

Author : Hossein Baharvand
Publisher : Springer Science & Business Media
ISBN 13 : 1627030980
Total Pages : 318 pages
Book Rating : 4.6/5 (27 download)

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Book Synopsis Regenerative Medicine and Cell Therapy by : Hossein Baharvand

Download or read book Regenerative Medicine and Cell Therapy written by Hossein Baharvand and published by Springer Science & Business Media. This book was released on 2012-08-09 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: Therapeutic applications within regenerative biomedicine has gained tremendous interest from a growing, multidisciplinary community of investigators in recent years, driven by the hope of finding cures for several diseases. Regenerative Medicine and Cell Therapy discusses cutting-edge science in the field of regenerative biomedicine and its therapeutic applications to various medical disorders. The chapters are written by renowned scientists in the specific fields. This will be a useful book for basic and clinical scientists, especially young investigators and stem cell biology students who are newly entering the world of stem cells research. The editors’ goal is that the new knowledge and research outlined in this book will help contribute to new therapies for a wide variety of diseases that presently afflict humanity.

Wound Regeneration and Repair

Author : Robert G. Gourdie
Publisher : Humana Press
ISBN 13 : 9781627035040
Total Pages : 0 pages
Book Rating : 4.0/5 (35 download)

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Book Synopsis Wound Regeneration and Repair by : Robert G. Gourdie

Download or read book Wound Regeneration and Repair written by Robert G. Gourdie and published by Humana Press. This book was released on 2013-09-13 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Wound Regeneration and Repair: Methods and Protocols, expert researchers in the field detail classical and cutting-edge methods for studying wound healing and regeneration. These techniques include cellular and molecular methods, genetic approaches, surgical procedures, clinical advances, drug discovery and delivery modalities, animal and humanized models and new applications in the treatment of pathological wounds in a variety of organs and tissues. Written in the highly successful Methods in Molecular Biology series format, chapters include an introduction to their respective topics, a detailed list of the necessary materials and reagents for each procedure, step-by-step, reproducible laboratory protocols, and a set notes, developed by the authors, for troubleshooting and avoiding known pitfalls. Authoritative and practical, Wound Regeneration and Repair: Methods and Protocols seeks to aid scientists and entrepreneurs in their further study of technologies, models, techniques, and critical new areas and approaches to clinical and commercial translation of research.

Stem Cells in Regenerative Medicine

Author : Alain A. Vertes
Publisher : John Wiley & Sons
ISBN 13 : 111997139X
Total Pages : 788 pages
Book Rating : 4.1/5 (199 download)

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Book Synopsis Stem Cells in Regenerative Medicine by : Alain A. Vertes

Download or read book Stem Cells in Regenerative Medicine written by Alain A. Vertes and published by John Wiley & Sons. This book was released on 2015-12-02 with total page 788 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a unique guide to emerging stem cell technologies and the opportunities for their commercialisation. It provides in-depth analyses of the science, business, legal, and financing fundamentals of stem cell technologies, offering a holistic assessment of this emerging and dynamic segment of the field of regenerative medicine. • Reviews the very latest advances in the technology and business of stem cells used for therapy, research, and diagnostics • Identifies key challenges to the commercialisation of stem cell technology and avenues to overcome problems in the pipeline • Written by an expert team with extensive experience in the business, basic and applied science of stem cell research This comprehensive volume is essential reading for researchers in cell biology, biotechnology, regenerative medicine, and tissue engineering, including scientists and professionals, looking to enter commercial biotechnology fields.

Stem Cells and Cell Therapy

Author : Mohamed Al-Rubeai
Publisher : Springer Science & Business Media
ISBN 13 : 9400771967
Total Pages : 189 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Stem Cells and Cell Therapy by : Mohamed Al-Rubeai

Download or read book Stem Cells and Cell Therapy written by Mohamed Al-Rubeai and published by Springer Science & Business Media. This book was released on 2013-10-01 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the discovery of stem cells capable of multiplying indefinitely in culture and differentiating into many other cell types in appropriate conditions, new hopes were born in repair and replacement of damaged cells and tissues. The features of stem cells may provide treatment for some incurable diseases with some therapies are already in clinics, particularly those from adult stem cells. Some treatments will require large number of cells and may also require multiple doses, generating a growing demand for generating and processing large numbers of cells to meet the need of clinical applications. With this in mind, our aim is to provide a book on the subject of stem cells and cell therapy for researchers and students of cell biotechnology, bioengineering and bioproduction. This book is exceptional as it teaches researchers stem cells and cell therapy in that it covers the concepts and backgrounds necessary so that readers get a good understanding of the production of stem cells. The book covers three topics: The basics of stem cells and cell therapy, the use of stem cells for the treatment of human diseases, and stem cell processing. It includes chapters on neural and vascular stem vascular stem cell therapy, expansion engineering of embryonic stem cells, stem cell based production of blood cells and separation technologies for stem cells and cell therapy products. It is an informed and informative presentation of what modern research, science and engineering have learned about stem cells and their production and therapies. Addressing both the medical and production issues, this book is an invaluable contribution to having an academic and industrial understanding with respect to R&D and manufacturing of clinical grade stem cells.

Bone marrow stem cell therapy for stroke

Author : Kunlin Jin
Publisher : Springer
ISBN 13 : 9811029296
Total Pages : 332 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Bone marrow stem cell therapy for stroke by : Kunlin Jin

Download or read book Bone marrow stem cell therapy for stroke written by Kunlin Jin and published by Springer. This book was released on 2016-12-13 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers recent advances in all aspects of bone marrow-derived stem cells (BMSCs) for stroke treatment, while also providing comprehensive information on human clinical trials and animal models of stroke. In addition, it reviews the optimal conditions of transplantation for stroke therapy and potential mechanisms underlying transplanted cell-mediated functional recovery after stroke. As the first book to focus on BMSC therapy for stroke, it also discusses in depth the unique challenges of BMSCs-based therapy in this context.

Stem Cells

Author : Lygia V Pereira
Publisher : World Scientific
ISBN 13 : 9813100214
Total Pages : 108 pages
Book Rating : 4.8/5 (131 download)

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Book Synopsis Stem Cells by : Lygia V Pereira

Download or read book Stem Cells written by Lygia V Pereira and published by World Scientific. This book was released on 2016-08-22 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stem Cells: Promises and Reality will tell you everything you have always wanted to know about stem cells, but could not understand the field from elsewhere. Stem cells are the great therapeutic promise of the century, and this evolving field of research and medicine brings with it many legal, ethical and psychological issues that must be discussed by society as a whole. Written so as to be accessible to general readers as well as specialists, this book explains what stem cells are, and the different aspects of stem cell research and applications. The book will enable the reader to understand the field sufficiently to critically participate in the public debates regarding stem cell research and society and ethics. By the end of the book, the reader will also be able to judge news on the stem cells field, and to discern what are real advances and what are phony treatments. The main advantage of this book in comparison with other "stem cells for the general public" books is that it assumes the reader knows NOTHING about biology, except what is already common knowledge (for example, that we are made of cells). The book constructs step by step the required basic biology knowledge in order for the reader to understand all the different aspects of stem cells. At the same time that it is thorough in its stem cells-based content, and will keep the reader engaged with its narrative.

Stem Cells in the Respiratory System

Author : Mauricio Rojas
Publisher : Springer Science & Business Media
ISBN 13 : 1607617757
Total Pages : 170 pages
Book Rating : 4.6/5 (76 download)

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Book Synopsis Stem Cells in the Respiratory System by : Mauricio Rojas

Download or read book Stem Cells in the Respiratory System written by Mauricio Rojas and published by Springer Science & Business Media. This book was released on 2010-08-05 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this state-of-the-art exploration of a hugely dynamic and fast-evolving field of research, leading researchers share their collective wisdom on the role that stem cells could play in the context of physiological stress and lung injury. The text focuses on reviewing the most relevant—and recent—ideas on using local, endogenous, and exogenous progenitor/stem cells in preventing and treating injury to the lung. The lungs are one of the most complex organs in the human body, with a mature adult lung boasting at least 40 morphologically differentiated cell lineages. Our entire blood supply passes through the lung’s alveolar units during oxygenation. This interaction with the outside world, along with the intricacies of its structure, makes the lung a highly susceptible organ that is vulnerable to numerous types of injury and infection. This means that the mechanisms of lung repair are in themselves correspondingly complex. Because of their multipotentiality, as well as the fact of the lung’s relatively rapid cell turnover, stem cells are thought to be an important alternative cell-base therapy in lung injury. Despite the controversial nature of stem cell research, there has been growing interest in both local and endogenous stem cells in the lung. This highly topical book with chapters on everything from using mesenchymal stem cells in lung repair to the effect of physical activity on the mobilization of stem and progenitor cells, represents an exciting body of work by outstanding investigators and will be required reading for those with an interest in the subject.

Translational Regenerative Medicine

Author : Anthony Atala
Publisher : Academic Press
ISBN 13 : 0124104576
Total Pages : 606 pages
Book Rating : 4.1/5 (241 download)

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Book Synopsis Translational Regenerative Medicine by : Anthony Atala

Download or read book Translational Regenerative Medicine written by Anthony Atala and published by Academic Press. This book was released on 2014-12-01 with total page 606 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translational Regenerative Medicine is a reference book that outlines the life cycle for effective implementation of discoveries in the dynamic field of regenerative medicine. By addressing science, technology, development, regulatory, manufacturing, intellectual property, investment, financial, and clinical aspects of the field, this work takes a holistic look at the translation of science and disseminates knowledge for practical use of regenerative medicine tools, therapeutics, and diagnostics. Incorporating contributions from leaders in the fields of translational science across academia, industry, and government, this book establishes a more fluid transition for rapid translation of research to enhance human health and well-being. Provides formulaic coverage of the landscape, process development, manufacturing, challenges, evaluation, and regulatory aspects of the most promising regenerative medicine clinical applications Covers clinical aspects of regenerative medicine related to skin, cartilage, tendons, ligaments, joints, bone, fat, muscle, vascular system, hematopoietic /immune system, peripheral nerve, central nervous system, endocrine system, ophthalmic system, auditory system, oral system, respiratory system, cardiac system, renal system, hepatic system, gastrointestinal system, genitourinary system Identifies effective, proven tools and metrics to identify and pursue clinical and commercial regenerative medicine

Mesenchymal Stem Cell Therapy

Author : Lucas G. Chase
Publisher : Springer Science & Business Media
ISBN 13 : 1627032002
Total Pages : 458 pages
Book Rating : 4.6/5 (27 download)

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Book Synopsis Mesenchymal Stem Cell Therapy by : Lucas G. Chase

Download or read book Mesenchymal Stem Cell Therapy written by Lucas G. Chase and published by Springer Science & Business Media. This book was released on 2012-12-12 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past decade, significant efforts have been made to develop stem cell-based therapies for difficult to treat diseases. Multipotent mesenchymal stromal cells, also referred to as mesenchymal stem cells (MSCs), appear to hold great promise in regards to a regenerative cell-based therapy for the treatment of these diseases. Currently, more than 200 clinical trials are underway worldwide exploring the use of MSCs for the treatment of a wide range of disorders including bone, cartilage and tendon damage, myocardial infarction, graft-versus-host disease, Crohn’s disease, diabetes, multiple sclerosis, critical limb ischemia and many others. MSCs were first identified by Friendenstein and colleagues as an adherent stromal cell population within the bone marrow with the ability to form clonogenic colonies in vitro. In regards to the basic biology associated with MSCs, there has been tremendous progress towards understanding this cell population’s phenotype and function from a range of tissue sources. Despite enormous progress and an overall increased understanding of MSCs at the molecular and cellular level, several critical questions remain to be answered in regards to the use of these cells in therapeutic applications. Clinically, both autologous and allogenic approaches for the transplantation of MSCs are being explored. Several of the processing steps needed for the clinical application of MSCs, including isolation from various tissues, scalable in vitro expansion, cell banking, dose preparation, quality control parameters, delivery methods and numerous others are being extensively studied. Despite a significant number of ongoing clinical trials, none of the current therapeutic approaches have, at this point, become a standard of care treatment. Although exceptionally promising, the clinical translation of MSC-based therapies is still a work in progress. The extensive number of ongoing clinical trials is expected to provide a clearer path forward for the realization and implementation of MSCs in regenerative medicine. Towards this end, reviews of current clinical trial results and discussions of relevant topics association with the clinical application of MSCs are compiled in this book from some of the leading researchers in this exciting and rapidly advancing field. Although not absolutely all-inclusive, we hope the chapters within this book can promote and enable a better understanding of the translation of MSCs from bench-to-bedside and inspire researchers to further explore this promising and quickly evolving field.

Stem Cells in Animal Species: From Pre-clinic to Biodiversity

Author : Tiziana A.L. Brevini
Publisher : Springer
ISBN 13 : 331903572X
Total Pages : 192 pages
Book Rating : 4.3/5 (19 download)

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Book Synopsis Stem Cells in Animal Species: From Pre-clinic to Biodiversity by : Tiziana A.L. Brevini

Download or read book Stem Cells in Animal Species: From Pre-clinic to Biodiversity written by Tiziana A.L. Brevini and published by Springer. This book was released on 2014-08-29 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume focuses on stem cell research and disease modeling in non-murine species. The book is divided into three parts: Stem Cells for Pre-Clinical Models, Stem Cells in Non-Conventional Species, and Stem Cell Banking for the Future. The first section presents an overview of the different pre-clinical stem cell models recently created in animal species, including the porcine model for heart failure, iPSC in large animal species, Duchenne muscular dystrophy and canine embryo-derived stem cells and modeling for human diseases. This section also discusses the potential advantages and applications of these models. The second part of this book describes recent efforts to use stem cells for preserving endangered species, including the snow leopard and coral reefs. From this perspective, stem cells are an invaluable tool to preserve bio-diversities. Frozen cells and gametes can be obtained from animals at risk of extinction and even from microorganisms and corals suffering from heavy changes in the eco-system; this may allow the cultivation of a generation of stem cell lines and represents an exciting opportunity to support and ensure the conservation of precious varieties of living creatures. This discussion leads easily into the third section, which discusses stem cell banking as a way of safeguarding these endangered species.

Cell Press Reviews: Stem Cells to Model and Treat Disease

Author : Cell Press
Publisher : Elsevier
ISBN 13 : 0127999167
Total Pages : 374 pages
Book Rating : 4.1/5 (279 download)

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Book Synopsis Cell Press Reviews: Stem Cells to Model and Treat Disease by : Cell Press

Download or read book Cell Press Reviews: Stem Cells to Model and Treat Disease written by Cell Press and published by Elsevier. This book was released on 2013-12-03 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cell Press Reviews: Stem Cells to Model and Treat Disease informs, inspires, and connects stem cell researchers and clinicians at all stages in their careers with timely, comprehensive reviews written by leaders in the field and curated by Cell Press editors. The publication offers a broad view of some of the most compelling topics in stem cell research including: Safety and efficacy of stem cell treatments Stem-cell-based organ regeneration Integrating stem cells into personalized drug discovery Using pluripotent stem cells for treating neurological disease Engineering hematopoietic stem cells for innovative therapies Contributions come from leading voices in the field, including: - Shinya Yamanaka, Recipient of the 2012 Nobel Prize for Physiology or Medicine, Recipient of the 2012 Millennium Technology Prize, Professor and Director of the Center for iPS Cell Research and Application at Kyoto University, Senior Investigator at the Gladstone Institute of Cardiovascular Disease, L.K. Whittier Foundation Investigator in Stem Cell Biology and Professor at the University of California, San Francisco - George Q. Daley, Samuel E. Lux IV Professor of Hematology/Oncology at Harvard Medical School and Director for the Stem Cell Transplantation Program at Boston Children’s Hospital - Irving Weissman, Member of National Academy of Sciences, Virgina & D.K Ludwig Professor for Clinical Investigation in Cancer Research, and Director for Institute of Stem Cell Biology and Regenerative Medicine at Stanford University of Medicine Cell Press Reviews: Stem Cells to Model and Treat Disease is part of the Cell Press Reviews series, which features reviews published in Cell Press primary research and Trends reviews journals. Provides timely overviews on a wide range of stem cell applications Offers insight from experts on the key opportunities and challenges facing the field Features reviews on genetic, cellular, and molecular aspects of stem-cell-based applications Includes articles originally published in Cell, Cell Stem Cell, Neuron, Trends in Molecular Medicine, and Trends in Biotechnology

Leading-edge Stem Cell Research

Author : Prasad S. Koka
Publisher : Nova Publishers
ISBN 13 : 9781604562682
Total Pages : 210 pages
Book Rating : 4.5/5 (626 download)

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Book Synopsis Leading-edge Stem Cell Research by : Prasad S. Koka

Download or read book Leading-edge Stem Cell Research written by Prasad S. Koka and published by Nova Publishers. This book was released on 2008 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents recent and important findings on stem cell research which is finding many applications including nervous system diseases, diabetes, heart disease, auto-immune diseases as well as Parkinson's disease, end-stage kidney disease, liver failure, cancer, spinal cord injury, multiple sclerosis and Alzheimer's disease. Stem cells are self-renewing, unspecialised cells that can give rise to multiple types all of specialised cells of the body. Stem cell research also involves complex ethical and legal considerations since they involve adult, foetal tissue and embryonic sources.