Angiotensin Ii Receptors

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Pocket Companion to Brenner and Rector's The Kidney

Author : Michael R. Clarkson
Publisher : Elsevier Health Sciences
ISBN 13 : 1455703788
Total Pages : 923 pages
Book Rating : 4.4/5 (557 download)

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Book Synopsis Pocket Companion to Brenner and Rector's The Kidney by : Michael R. Clarkson

Download or read book Pocket Companion to Brenner and Rector's The Kidney written by Michael R. Clarkson and published by Elsevier Health Sciences. This book was released on 2010-02-22 with total page 923 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pocket Companion to Brenner and Rector's The Kidney distills the essential clinical information from the latest edition of the seminal text on kidney diseases and their management. Michael R. Clarkson, Ciara Magee, and Barry M. Brenner detail the key pathophysiologic, diagnostic, and treatment issues in clinical nephrology, including interventional nephrology, endocrine aspects of kidney disease, and plasmapheresis. - Diagnose, treat, and manage both common and uncommon disorders. - Find clinical knowledge quickly and easily thanks to convenient tables throughout the text. - Choose the best option of the many techniques available through discussions of indications for laboratory tests and imaging studies.Enhance your clinical acumen with coverage of new topics such as risk factors and kidney disease, nephron endowment, interventional nephrology, plasmapheresis, xenotransplantation, stem cells in renal biology and medicine, and more. Stay current thanks to two new sections—Epidemiology and Risk Factors in Kidney Disease and Frontiers in Kidney Disease—that include topics such as stem cell and genomics.

The Protective Arm of the Renin Angiotensin System (RAS)

Author : Thomas Unger
Publisher : Academic Press
ISBN 13 : 0128014857
Total Pages : 312 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis The Protective Arm of the Renin Angiotensin System (RAS) by : Thomas Unger

Download or read book The Protective Arm of the Renin Angiotensin System (RAS) written by Thomas Unger and published by Academic Press. This book was released on 2015-04-18 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Protective Arm of the Renin Angiotensin System: Functional Aspects and Therapeutic Implications is the first comprehensive publication to signal the protective role of a distinct part of the renin–angiotensin system (RAS), providing readers with early insight into a complex system which will become of major medical importance in the near future. Focusing on recent research, The Protective Arm of the Renin Angiotensin System presents a host of new experimental studies on specific components of the RAS, namely angiotensin AT2 receptors (AT2R), the angiotensin (1–7) peptide with its receptor Mas, and the enzyme ACE 2, which exert significant beneficial, health-promoting actions by counterbalancing the well-known harmful arm of the RAS with its classical angiotensin AT1 receptor. This innovative concept of the protective arm of the RAS, examined in this reference, represents an indispensable background and will be a strong support for biomedical students, researchers, cardiologists, surgeons, nephrologists, diabetologists, and endocrinologists, as well as any other physician or researcher concerned with RAS physiology, pathophysiology and clinical implications. - Provides a complete understanding of the protective side of the Renin Angiotensin System (RAS) involving angiotensin AT2 receptor, ACE2, and Ang(1-7)/Mas receptor - Combines the knowledge of editors who pioneered research on the protective renin angiotensin system including; Dr. Thomas Unger, one of the founders of AT2 receptor research; Dr. Ulrike M. Steckelings, who contributed significantly to first preclinical studies with a novel specific AT2-agonist, and Dr. Robson Santos who pioneered research on angiotensin-(1-7) and its receptor Mas. - Shows that the protective RAS axes are able to ameliorate the course of several cardiovascular, renal, metabolic and neurological diseases - Provides the basis for the understanding of a novel therapeutic approach to stimulate components of the protective arm of the RAS.

Essentials of Cardiac Anesthesia for Noncardiac Surgery E-Book

Author : Joel A. Kaplan
Publisher : Elsevier Health Sciences
ISBN 13 : 0323567126
Total Pages : 649 pages
Book Rating : 4.3/5 (235 download)

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Book Synopsis Essentials of Cardiac Anesthesia for Noncardiac Surgery E-Book by : Joel A. Kaplan

Download or read book Essentials of Cardiac Anesthesia for Noncardiac Surgery E-Book written by Joel A. Kaplan and published by Elsevier Health Sciences. This book was released on 2018-07-21 with total page 649 pages. Available in PDF, EPUB and Kindle. Book excerpt: Patients with cardiac conditions routinely present for noncardiac surgeries, requiring special protocols for perioperative assessment and management by the anesthesiologist. Essentials of Cardiac Anesthesia for Noncardiac Surgery: A Companion to Kaplan's Cardiac Anesthesia provides current, easily accessible information in this complex area, ideal for general anesthesiologists and non-cardiac subspecialists. From preoperative assessment through postoperative care, this practical reference covers all perioperative approaches to today's patients with cardiac conditions. - Provides guidance on the anesthetic diagnosis and management of the full range of cardiac lesions, helping minimize adverse outcomes and reduce complications for patients with common, complex, or uncommon cardiac conditions. - Includes complete coverage of echocardiography and current monitoring techniques needed for thorough perioperative assessment – all from the anesthesiologist's perspective. - Discusses safe and effective perioperative anesthetic management of patients presenting with advanced levels of cardiac care such as drug-eluting stents, multiple antiplatelet drugs, ventricular assist devices, multiple drugs for end-stage heart failure, and implanted electrical devices that produce cardiac resynchronization therapy, as well as patients with complicated obstetric problems or other significant cardiovascular issues. - Features a concise, easy-to-navigate format and Key Points boxes in each chapter that help you find answers quickly.

Heart Physiology and Pathophysiology

Author : Yoshihisa Kurachi
Publisher : Elsevier
ISBN 13 : 0080533884
Total Pages : 1286 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Heart Physiology and Pathophysiology by : Yoshihisa Kurachi

Download or read book Heart Physiology and Pathophysiology written by Yoshihisa Kurachi and published by Elsevier. This book was released on 2000-10-09 with total page 1286 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heart Physiology and Pathophysiology, 4E, provides the foundation for the scientific understanding of heart function and dysfunction, and bridges the gap between basic cardiovascular science and clinical cardiology. This comprehensive text covers all the important aspects of the heart and vascular system. The most important and relevant disorders are presented, with emphasis on the mechanisms involved. The first three editions of this book developed a reputation as the leading reference in cardiovascular science for researchers and academic cardiologists. This recent edition has been updated, expanded, and includes a number of new contributors. It has also been remodeled to expand its usage as a text reference for cardiology residents, practicing cardiologists, and graduate students.Key Features* The most comprehensive book available on this topic* Clear, concise, and complete coverage of all important aspects of cardiovascular physiology/pathophysiology* Completely updated version of the foremost reference on cardiovascular science, including new information on pathophysiology and electrophysiology* Useful tool in bridging the gap between basic science, pathophysiology, and clinical cardiology

Ccn Proteins: A New Family Of Cell Growth And Differentiation Regulators

Author : Masaharu Takigawa
Publisher : World Scientific
ISBN 13 : 1783260335
Total Pages : 324 pages
Book Rating : 4.7/5 (832 download)

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Book Synopsis Ccn Proteins: A New Family Of Cell Growth And Differentiation Regulators by : Masaharu Takigawa

Download or read book Ccn Proteins: A New Family Of Cell Growth And Differentiation Regulators written by Masaharu Takigawa and published by World Scientific. This book was released on 2005-06-17 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: The CCN Proteins are thought to play key roles in the biology of normal cell, tissue, organ, and body, and altered expression of CCN proteins is associated with several pathologies, including fibrosis and cancer. Because of its importance, the CCN field is expanding at a fast pace. Research articles in this field have recently increased logarithmically, and a book that is up-to-date, comprehensive, authoritative and affords insights into the biological roles of CCN proteins, is timely.CCN Protein: A New Family of Cell Growth and Differentiation Regulators presents the most recent progress in the field of CCN proteins, a new family of secretory signaling molecules that are involved in several fundamental biological progress. These proteins share a unique multimodular organization and present a partial identity with four families of regulatory proteins controling growth and development. The book covers the roles of CCN proteins in the control of cell proliferation and differentiation during normal development, wound repair, chondrogenesis and bone development, angiogenesis, tissue regeneration, fibrosis, renal diseases and cancer development.

Integration of Pharmaceutical Discovery and Development

Author : Ronald T. Borchardt
Publisher : Springer Science & Business Media
ISBN 13 : 0306473844
Total Pages : 627 pages
Book Rating : 4.3/5 (64 download)

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Book Synopsis Integration of Pharmaceutical Discovery and Development by : Ronald T. Borchardt

Download or read book Integration of Pharmaceutical Discovery and Development written by Ronald T. Borchardt and published by Springer Science & Business Media. This book was released on 2006-01-19 with total page 627 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the late 1980s, it became painfully evident to the pharmaceutical industry that the old paradigm of drug discovery, which involved highly segmented drug - sign and development activities, would not produce an acceptable success rate in the future. Therefore, in the early 1990s a paradigm shift occurred in which drug design and development activities became more highly integrated. This new str- egy required medicinal chemists to design drug candidates with structural f- tures that optimized pharmacological (e. g. , high affinity and specificity for the target receptor), pharmaceutical (e. g. , solubility and chemical stability), bioph- maceutical (e. g. , cell membrane permeability), and metabolic/pharmacokinetic (e. g. , metabolic stability, clearance, and protein binding) properties. Successful implementation of this strategy requires a multidisciplinary team effort, incl- ing scientists from drug design (e. g. , medicinal chemists, cell biologists, en- mologists, pharmacologists) and drug development (e. g. , analytical chemists, pharmaceutical scientists, physiologists, and molecular biologists representing the disciplines of pharmaceutics, biopharmaceutics, and pharmacokinetics/drug metabolism). With this new, highly integrated approach to drug design now widely utilized by the pharmaceutical industry, the editors of this book have provided the sci- tific community with case histories to illustrate the nature of the interdisciplinary interactions necessary to successfully implement this new approach to drug d- covery. In the first chapter, Ralph Hirschmann provides a historical perspective of why this paradigm shift in drug discovery has occurred.

Sex Differences in Cardiovascular Physiology and Pathophysiology

Author : Babbette LaMarca
Publisher : Academic Press
ISBN 13 : 0128131977
Total Pages : 392 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Sex Differences in Cardiovascular Physiology and Pathophysiology by : Babbette LaMarca

Download or read book Sex Differences in Cardiovascular Physiology and Pathophysiology written by Babbette LaMarca and published by Academic Press. This book was released on 2019-04-11 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sex Differences in Cardiovascular Physiology and Pathophysiology is a comprehensive look into the often overlooked and underappreciated fundamental sex differences between men and women and how those differences affect the cardiovascular system. It covers cardiovascular function, anatomy, cell signaling and the development of pathology. With contributions from world-renowned research investigators, this up-to-date reference compiles critical knowledge on cardiovascular sex differences, providing researchers and clinicians with a better understanding of the diagnosis, prevention and treatment of cardiovascular diseases in both men and women.

Encyclopedia of Heart Diseases

Author : M. Gabriel Khan
Publisher : Elsevier
ISBN 13 : 008045481X
Total Pages : 678 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Encyclopedia of Heart Diseases by : M. Gabriel Khan

Download or read book Encyclopedia of Heart Diseases written by M. Gabriel Khan and published by Elsevier. This book was released on 2005-12-14 with total page 678 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Encyclopedia of Heart Diseases is an accurate and reliable source of in-depth information on the diseases that kill more than 12 million individuals worldwide each year. In fact, cardiovascular diseases are more prevalent than the combined incidence of all forms of cancer, diabetes, asthma and leukemia. In one volume, this Encylopedia thoroughly covers these ailments and also includes in-depth analysis of less common and rare heart conditions to round out the volume's scope. Researchers, clinicians, and students alike will all find this resource an invaluable tool for quick reference before approaching the primary literature.* Coverage of more than 200 topics, including: applied pharmacology of current and experimental cardiac drugs, gene therapy, MRI, electron-beam CT, PET scan put in perspective, cardiac tests costs and justification, and new frontiers in cardiovascular research* More than 150 helpful figures and illustrations!* Dr. Khan is a well-published and respected expert in heart and heart diseases

Report of the Joint National Committee on Detection, Evaluation, and Treatment of High Blood Pressure

Author : Joint National Committee on Detection, Evaluation, and Treatment of High Blood Pressure
Publisher :
ISBN 13 :
Total Pages : 20 pages
Book Rating : 4.3/5 (121 download)

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Book Synopsis Report of the Joint National Committee on Detection, Evaluation, and Treatment of High Blood Pressure by : Joint National Committee on Detection, Evaluation, and Treatment of High Blood Pressure

Download or read book Report of the Joint National Committee on Detection, Evaluation, and Treatment of High Blood Pressure written by Joint National Committee on Detection, Evaluation, and Treatment of High Blood Pressure and published by . This book was released on with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Renin Angiotensin System and the Heart

Author : Walmor C. De Mello
Publisher : Wiley-Blackwell
ISBN 13 :
Total Pages : 268 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Renin Angiotensin System and the Heart by : Walmor C. De Mello

Download or read book Renin Angiotensin System and the Heart written by Walmor C. De Mello and published by Wiley-Blackwell. This book was released on 2004-04-30 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent studies have shown that the heart possesses an intrinsic renin angiotensin system that is controlled by tissue-specific parameters that are activated by biomechanical stress. This book reviews the latest information on the way in which both the plasma and cardiac renin angiotensin systems affect heart function. It covers the cell and molecular biology of these systems, with contributions on renin synthesis, uptake and the intracellular signalling pathways. Particular insight comes from transgenic mouse models in which either mouse or human genes for various components of the renin angiotensin system are expressed. Other topics covered include wound healing as well as the trophic effects of aldosterone. Contains the most recent findings on the renin angiotensin system and the heart Written by an international team of distinguished scientists Covers both the cellular and molecular basis of the renin angiotensin system and the clinical relevance of this research

Aldosterone-Mineralocorticoid Receptor

Author : Brian Harvey
Publisher : BoD – Books on Demand
ISBN 13 : 1839621982
Total Pages : 302 pages
Book Rating : 4.8/5 (396 download)

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Book Synopsis Aldosterone-Mineralocorticoid Receptor by : Brian Harvey

Download or read book Aldosterone-Mineralocorticoid Receptor written by Brian Harvey and published by BoD – Books on Demand. This book was released on 2019-09-25 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is an open access dissemination of the EU COST Action ADMIRE in Aldosterone/Mineralocorticoid Receptor (MR) physiology and pathophysiology. Aldosterone is the major hormone regulating blood pressure. Alterations in blood levels of aldosterone and genetic mutations in the MR receptor are major causes of hypertension and comorbidities. Many of the drugs in clinical use, and in development for treating hypertension, target aldosterone and MR actions in the kidney and cardiovascular system. The ADMIRE book assembles review chapters from 16 European ADMIRE laboratories providing the latest insights into mechanisms of aldosterone synthesis/secretion, aldosterone/MR physiology and signaling, and the pathophysiological roles of aldosterone/MR activation.

Handbook of Biologically Active Peptides

Author : Abba Kastin
Publisher : Elsevier
ISBN 13 : 0080463797
Total Pages : 1682 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Handbook of Biologically Active Peptides by : Abba Kastin

Download or read book Handbook of Biologically Active Peptides written by Abba Kastin and published by Elsevier. This book was released on 2011-04-28 with total page 1682 pages. Available in PDF, EPUB and Kindle. Book excerpt: Peptides play a crucial role in many physiological processes including actions as neurotransmitters, hormones, and antibiotics. Research has shown their importance in such fields as neuroscience, immunology, pharmacology, and cell biology. The Handbook of Biologically Active Peptides presents, for the first time, this tremendous body of knowledge in the field of biologically active peptides in one single reference. The section editors and contributors represent some of the most sophisticated and distinguished scientists working in basic sciences and clinical medicine. The Handbook of Biologically Active Peptides is a definitive, all-encompassing reference that will be indispensable for individuals ranging from peptide researchers, to biochemists, cell and molecular biologists, neuroscientists, pharmacologists, and to endocrinologists. Chapters are designed to be a source for workers in the field and will enable researchers working in a specific area to examine other related areas with which they would not ordinarily be familiar.*Chapters are designed to be a source for workers in the field and will enable researchers working in a specific area to examine other related areas that they would not ordinarily be familiar.*Fascinating relationships described in the book include the presence of some peptides originally found in frog skin that persist in the human human and brain where they can affect food intake and obesity.

Thirst and Sodium Appetite

Author : Sebastian Peter Grossman
Publisher :
ISBN 13 :
Total Pages : 312 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Thirst and Sodium Appetite by : Sebastian Peter Grossman

Download or read book Thirst and Sodium Appetite written by Sebastian Peter Grossman and published by . This book was released on 1990 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thirst and Sodium Appetite ...

Encyclopedia of Hormones

Author : Helen Henry
Publisher : Academic Press
ISBN 13 :
Total Pages : 744 pages
Book Rating : 4.:/5 ( download)

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Book Synopsis Encyclopedia of Hormones by : Helen Henry

Download or read book Encyclopedia of Hormones written by Helen Henry and published by Academic Press. This book was released on 2003-06-13 with total page 744 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Encyclopedia of Hormones is a comprehensive reference work on hormones in vertebrate, invertebrate, and plant systems. It covers all aspects of hormones: their chemical structure and biological synthesis; the major physiological systems in which they operate; the cellular and subcellular site of their action; the nature of the signal transduction mechanisms used in the hormone's action; and the biological consequences of an excess or deficiency of the hormone. Each contributor is an expert in his or her field and has been recruited by one of 14 Associate Editors. The 300 articles that comprise this encyclopedia are arranged alphabetically. Each entry begins with a glossary of key terms that are compiled into a complete glossary for the entire work. Additionally, each entry includes 10-15 recent references to provide the reader with an entry into the scientific literature. The Encyclopedia of Hormones is sure to be a valuable reference work for students and professional researchers interested in any aspect of the control of biological systems by hormonal signals. The only source available with such comprehensive descriptions of hormones, their receptors, and their mechanisms of action Full coverage including vertebrate, invertebrate, and plant hormones Includes the chemistry, synthesis, secretion, and biological actions of hormones Thorough coverage of signal transduction mechanisms as they relate to hormones Contributions from over 500 experts in the study of hormones Written to be accesssible to non-endocrinologists

The Hypertrophied Heart

Author : Nobuakira Takeda
Publisher : Springer Science & Business Media
ISBN 13 : 9780792377412
Total Pages : 490 pages
Book Rating : 4.3/5 (774 download)

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Book Synopsis The Hypertrophied Heart by : Nobuakira Takeda

Download or read book The Hypertrophied Heart written by Nobuakira Takeda and published by Springer Science & Business Media. This book was released on 2000-09-30 with total page 490 pages. Available in PDF, EPUB and Kindle. Book excerpt: Whenever the heart is challenged with an increased work load for a prolonged period, it responds by increasing its muscle mass--a phenomenon known as cardiac hypertrophy. Although cardiac hypertrophy is commonly seen under physiological conditions such as development and exercise, a wide variety of pathological situa tions such as hypertension (pressure overload), valvular defects (volume overload), myocardial infarction (muscle loss), and cardiomyopathy (muscle disease) are also known to result in cardiac hypertrophy. Various hormones such as catecholamines, thyroid hormones, angiotensin II, endothelin, and growth factors have also been shown to induce cardiac hypertrophy. Although the exact mechanisms underlying or pathological forrns of cardiac hypertrophy are poorly under the physiological stood, an increase in the intraventricular pressure is believed to represent the major stimulus for the development of cardiac hypertrophy. In this regard, stretching of the cardiac muscle has been shown to induce the hypertrophic response, but the role of metabolic influences in this process cannot be ruled out. Furthermore, different hormones and other interventions in the absence of stretch have been observed to stimulate protein synthesis in both isolated cardiomyocyte and vascular myocyte preparations. Nonetheless, it is becoming dear that receptor as well as phospholipid linked signal transduction pathways are activated in some specific manner depend ing upon the initial hypertrophic stimulus, and these then result in an increase in the size and mass of cardiomyocytes.

Encyclopedic Reference of Molecular Pharmacology

Author : Stefan Offermanns
Publisher :
ISBN 13 :
Total Pages : 1152 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Encyclopedic Reference of Molecular Pharmacology by : Stefan Offermanns

Download or read book Encyclopedic Reference of Molecular Pharmacology written by Stefan Offermanns and published by . This book was released on 2004 with total page 1152 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents current information on the molecular mechanisms of drug action. Provides 159 essays describing groups of drugs and drug targets. Several essays deal with general principles of pharmacology, such as drug tolerance, drug addiction, or drug metabolism.

Receptors in the Human Nervous System

Author : Frederick A. O. Mendelsohn
Publisher :
ISBN 13 :
Total Pages : 280 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Receptors in the Human Nervous System by : Frederick A. O. Mendelsohn

Download or read book Receptors in the Human Nervous System written by Frederick A. O. Mendelsohn and published by . This book was released on 1991 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: A synthesis of the results of receptor mapping in the human nervous system, including photographs clearly showing the distribution of specific receptors. Recognizes that the field is in a major transition period: receptor autoradiography has recently allowed the study of postmortem human brains, as well as those of experimental animals; and positron emission tomography is now allowing the study of live human brains. The information presented is therefore intended not only to be of use itself, but to serve as a background for the new information expected shortly. Annotation copyrighted by Book News, Inc., Portland, OR