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Author : Shoo Peng Siah
Publisher :
ISBN 13 :
Total Pages : 197 pages
Book Rating : 4.:/5 (224 download)
Download or read book An Investigation of the Molecular Pathogenesis of Endometrial Cancer written by Shoo Peng Siah and published by . This book was released on 2002 with total page 197 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Paola Viganò
Publisher : MDPI
ISBN 13 : 3039214950
Total Pages : 378 pages
Book Rating : 4.0/5 (392 download)
Download or read book Molecular Research of Endometrial Pathophysiology written by Paola Viganò and published by MDPI. This book was released on 2019-10-14 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: The endometrium has been the subject of intense research in a variety of clinical settings, because of its importance in the reproductive process and its role in women’s health. In the past 15 years, significant efforts have been invested in defining the molecular phenotype of the receptive phase endometrium as well as of various endometrial pathologies. Although this has generated a wealth of information on the molecular landscape of human endometrium, there is a need to complement this information in light of the novel methodologies and innovative technical approaches. The focus of this International Journal of Molecular Sciences Special Issue is on molecular and cellular mechanisms of endometrium and endometrium-related disorders. The progress made in the molecular actions of steroids, in the metabolism of steroids and intracrinology, in endometrial intracellular pathways, in stem cells biology, as well as in the molecular alterations underlying endometrium-related pathologies has been the focus of the reviews and papers included.]
Author : Michael T. Deavers
Publisher : Springer
ISBN 13 : 3319579851
Total Pages : 288 pages
Book Rating : 4.3/5 (195 download)
Download or read book Precision Molecular Pathology of Uterine Cancer written by Michael T. Deavers and published by Springer. This book was released on 2017-10-28 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text provides a comprehensive review for practicing pathologists to understand the molecular biology, diagnostics, and predictive markers and implications for therapy of uterine cancer. While molecular based therapeutic strategies for uterine cancer are not as well developed as for some other organ sites, these are the most common gynecologic malignancies and there have been many important recent developments that are discussed in this volume. Comprehensive chapters address essential information about endometrial carcinoma, uterine mesenchymal tumors, and cervical carcinoma and include the pathogenesis of carcinoma and discuss molecular based classification, biomarkers, therapy, prevention, and hereditary cancers of the uterus. Precision Molecular Pathology of Uterine Cancer is a unique and one of a kind resource for practicing pathologists, pathologists in training and gynecologists.
Author : Antonio Giordano
Publisher : Springer Science & Business Media
ISBN 13 : 1597453463
Total Pages : 226 pages
Book Rating : 4.5/5 (974 download)
Download or read book Molecular Pathology of Gynecologic Cancer written by Antonio Giordano and published by Springer Science & Business Media. This book was released on 2007-10-05 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on putting successful molecular strategies into practice for the treatment of gynecologic cancer. It approaches research into the pathology and treatment of gynecologic oncology from both clinical and experimental perspectives. New insights made possible by the introduction of advanced technologies into the field are presented. This new volume will be necessary reading for clinicians and experimental researchers alike.
Author : Sumita Mehta
Publisher : Springer Nature
ISBN 13 : 9811553173
Total Pages : 306 pages
Book Rating : 4.8/5 (115 download)
Download or read book Recent Advances in Endometrial Cancer written by Sumita Mehta and published by Springer Nature. This book was released on 2020-07-23 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses in detail the recent advances in the management of endometrial cancer, including the latest therapies and diagnostic methods. The book focuses on treatment-oriented topics such as the role of lymphadenectomy and sentinel node dissection, surgical complications, radiation techniques, and chemotherapy in endometrial cancer, and also explores treatment options in advanced disease stages, including hormonal therapy and targeted therapy. Providing insights into the evidence-based management guidelines for endometrial cancer, this book is a valuable resource for students, trainees and practitioners in the field of gynecology and gyne-oncology.
Author : Lora Hedrick Ellenson
Publisher : Springer
ISBN 13 : 3319431390
Total Pages : 284 pages
Book Rating : 4.3/5 (194 download)
Download or read book Molecular Genetics of Endometrial Carcinoma written by Lora Hedrick Ellenson and published by Springer. This book was released on 2016-12-01 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive text provides a much-needed review of a disease that is currently garnering the interest of molecular biologists, translational scientists, and clinicians. The volume includes emerging developments in the molecular genetics of endometrial carcinoma. In addition to covering the basic genetics of endometrial carcinoma, chapters also cover a wide range of signaling pathways implicated in endometrial carcinoma. A section of the book includes a number of genetically engineered mouse models, which contribute to understanding the role of various genetic alterations in the development and progression of endometrial carcinoma. These models also provide preclinical models for developing effective targeted therapeutic approaches. Endometrial carcinoma is the most common malignancy of the female genital tract in the United States and the number of cases continues to increase around the world. This book is a meant to serve as a resource for a wide range of scientists, from molecular geneticists to signal transduction biologists, as well as to both clinicians and scientists interested in developing targeted therapeutic approaches for women with endometrial carcinoma.
Author : Kevin M. Haigis, Ph.D.
Publisher : Springer Science & Business Media
ISBN 13 : 146148412X
Total Pages : 319 pages
Book Rating : 4.4/5 (614 download)
Download or read book Molecular Pathogenesis of Colorectal Cancer written by Kevin M. Haigis, Ph.D. and published by Springer Science & Business Media. This book was released on 2013-10-02 with total page 319 pages. Available in PDF, EPUB and Kindle. Book excerpt: Colorectal cancer has for more than two decades served as the paradigm for the multi-step concept of cancer initiation and progression. Perhaps more than any other organ site, cancer of the colon is extensively characterized at the molecular level. We are now entering a time when molecular classification, rather than histologic classification, of cancer subtypes is driving the development of clinical trials with emerging targeted therapies. The book will focus on the progression from the identification of mutations that drive colorectal cancer initiation and progression to the search for novel therapies to treat the disease.
Author : David M. Luesley
Publisher : CRC Press
ISBN 13 : 9780824759513
Total Pages : 320 pages
Book Rating : 4.7/5 (595 download)
Download or read book Uterine Cancer written by David M. Luesley and published by CRC Press. This book was released on 2005-09-23 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: This authoritative reference compiles the latest studies on the epidemiology, diagnosis, and treatment of uterine cancer and offers an extensive review of the molecular pathogenesis of endometrial and uterine disorders-analyzing patterns of disease presentation as population demographics change and considering the challenges this will place on future healthcare procedures.
Author : Jesse Philip Greenstein
Publisher :
ISBN 13 : 9780120066674
Total Pages : 328 pages
Book Rating : 4.0/5 (666 download)
Download or read book Advances in Cancer Research written by Jesse Philip Greenstein and published by . This book was released on 1953 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Seiji Isonishi
Publisher : Springer Nature
ISBN 13 : 9813360135
Total Pages : 171 pages
Book Rating : 4.8/5 (133 download)
Download or read book Molecular Diagnosis and Targeting for Gynecologic Malignancy written by Seiji Isonishi and published by Springer Nature. This book was released on 2021-03-05 with total page 171 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book summarizes the important developments in the field of cancer research, specifically uterine cervical/endometrial cancer and ovarian cancer. It highlights the recent advances in gynecologic cancer, such as next generation models of genetically engineered animal models or cancer cell lines, focusing on their significance for advancing our understanding of gynecologic cancer biology, prevention and treatment, and drug response and resistance. Cancer research in the area of gynecologic tumors has undergone an enormous transformation over the past decade, with a greater understanding of tumor biology, elucidation of novel targets for therapeutic intervention, and better recognition of genetic predisposition syndromes. At the same time, the recent advances in basic cancer research have provided key insights into all aspects of gynecologic cancer biology, including developmental pathways and the impact of lineage plasticity, understanding metastatic progression, uncovering the roles of the tumor microenvironment , exploring tumor evolution, and discovering new therapeutic approaches and mechanisms of drug sensitivity and adaptive response. Molecular Diagnosis and Targeting for Gynecologic Malignancy appeals to investigators, clinicians, residents and postdocs who are curious about new research on gynecologic malignancies. It not only presents basic and translational research, but also explores the generalizability of the evidence covering the interface between basic and clinical science. Furthermore, a number of the topics offer the basis for new ideas that have the potential to advance into the gynecologic malignancies. This book provides readers with state-of-the-art information that will help improve the lives of patients with these challenging diseases.
Author : Mansoor R. Mirza
Publisher : Springer
ISBN 13 : 3319645137
Total Pages : 324 pages
Book Rating : 4.3/5 (196 download)
Download or read book Management of Endometrial Cancer written by Mansoor R. Mirza and published by Springer. This book was released on 2019-08-26 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: This practical reference book provides up-to-date, evidence-based multidisciplinary guidelines on the epidemiology, biology, diagnosis, and treatment of endometrial cancer. Individual chapters focus on topics such as hormonal interactions, cancer prevention, genetic classification and its clinical applications. Recent advances in diagnostic methods are described. The treatment-oriented chapters include coverage of the roles of lymphadenectomy and sentinel node dissection, surgical complications, radiation techniques, and chemotherapy in early-stage disease. Treatment options in advanced disease, including hormonal therapy and targeted therapy, are considered separately, as is the management of rare tumor types. The authors are international key opinion leaders. Summaries of the ESMO/ESGO/ESTRO guidelines on management are included. Each clinical chapter ends with a summary of recommendations with the level of evidence.
Author : Dr. Spineanu Eugenia
Publisher : Dr. Spineanu Eugenia
ISBN 13 :
Total Pages : 94 pages
Book Rating : 4./5 ( download)
Download or read book Endometrial Cancer: A Comprehensive Medical Treatise written by Dr. Spineanu Eugenia and published by Dr. Spineanu Eugenia. This book was released on 2024-03-03 with total page 94 pages. Available in PDF, EPUB and Kindle. Book excerpt: Endometrial cancer, a malignancy originating from the inner lining of the uterus, stands as a significant health concern for women worldwide. This treatise offers an exhaustive exploration of endometrial cancer, weaving together historical context, cutting-edge research, and holistic approaches to both treatment and prevention. Designed for medical professionals, researchers, and patients alike, the content delves deep into the intricacies of the disease, ensuring a thorough understanding for all readers. The treatise begins by tracing the historical evolution of endometrial cancer research, highlighting key milestones and breakthroughs that have shaped our current understanding. This historical perspective sets the stage for a detailed examination of the global epidemiology and demographics of the disease, emphasizing its prevalence, risk factors, and the populations most affected. A deep dive into the anatomy and physiology of the endometrium provides readers with a foundational understanding of its structure, function, and the hormonal dynamics that influence its health. This section is particularly crucial, as it lays the groundwork for understanding the cellular and molecular mechanisms that drive cancer development and progression. The heart of the treatise delves into the pathogenesis of endometrial cancer. From DNA mutations and chromosomal aberrations to hormonal pathways and the tumor microenvironment, readers are guided through the complex interplay of factors that contribute to the disease. Special attention is given to the metabolic alterations observed in cancer cells and the role of the immune system in tumor progression. Risk factors and preventative measures are explored in depth, with a focus on both genetic predispositions and lifestyle factors. The treatise emphasizes the importance of a holistic approach to prevention, incorporating diet, environmental exposures, and integrative medicine practices. Diagnostic methods, from symptomatic manifestations to advanced imaging techniques and molecular diagnostic tools, are meticulously detailed. This comprehensive overview ensures that readers are well-equipped to understand the nuances of diagnosis, from initial symptoms to confirmatory tests. Treatment modalities form a significant portion of the treatise, covering surgical techniques, radiation, chemotherapy, and emerging therapies like immunotherapy and targeted treatments. The content underscores the importance of personalized medicine, tailoring treatments to the unique genetic and molecular profile of each patient. Post-treatment care and rehabilitation are addressed with equal rigor. From surveillance protocols to physical therapy and nutritional guidance, the treatise offers a roadmap for patients navigating life after treatment. Psychological support, integrative medicine, and mind-body practices are highlighted, emphasizing the importance of holistic care in recovery. Special topics, including endometrial cancer in younger women, aggressive variants, and management in immunocompromised patients, are explored in detail, ensuring that readers are equipped to handle even the most challenging cases.
Author : Simone Ferrero
Publisher :
ISBN 13 : 9781536138870
Total Pages : 0 pages
Book Rating : 4.1/5 (388 download)
Download or read book Endometrial Cancer written by Simone Ferrero and published by . This book was released on 2018-07-02 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Endometrial cancer is the most common gynecological cancer and the sixth cause of cancer in developed countries. The findings that EC is a heterogeneous group of tumors with distinct risk factors and histopathological features, together with our improved understanding of its molecular mechanism has paved the way to the investigation of new surgical and medical therapies. The aim of this book is to give a complete overview on risk factors, pre-operative methods and management of endometrial cancer. The authors hope that this book will be a useful tool for any health provider involved in gynecological cancer care.
Author : Albert Altchek
Publisher : Elsevier
ISBN 13 : 008049451X
Total Pages : 595 pages
Book Rating : 4.0/5 (84 download)
Download or read book Diagnosis and Management of Ovarian Disorders written by Albert Altchek and published by Elsevier. This book was released on 2003-09-04 with total page 595 pages. Available in PDF, EPUB and Kindle. Book excerpt: This updated second edition of Diagnosis and Management of Ovarian Disorders provides thorough, yet succinct insight into the ever-changing realm of ovarian disorders. It presents a novel multidisciplinary approach to the subject as described by clinicians, surgeons, pathologists, basic scientists and related medical researchers. Topics covered include reproductive technology, early diagnosis of ovarian cancer, and management of menopause among others. The breadth of information provided by this book will appeal to clinicians and researchers involved in the study and treatment of ovarian disorders. KEY FEATURES* Includes updated information on early diagnosis of ovarian cancer* Reviews new diagnostic techniques for ovarian disorders* Discusses latest information on reproductive technology* Presents translational treatment linking laboratory research with clinical medicine
Author : Simon P. Langdon
Publisher : CRC Press
ISBN 13 : 9780849394430
Total Pages : 322 pages
Book Rating : 4.3/5 (944 download)
Download or read book Biology of Female Cancers written by Simon P. Langdon and published by CRC Press. This book was released on 1997-03-18 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biology of Female Cancers explores what can be learned about female cancers by summarizing what is known about the mechanisms of growth regulation and genetic features associated with common forms of female cancers, including malignancies of the breast, ovary, uterus, cervix, vulva, and gestational trophoblastic disease. The book describes the etiology, incidence, pathology, staging, and treatment of each type of cancer. The risk of developing particular tumor types and how their growth may be influenced by hormones, growth factors, and cytokines is also discussed. For oncologists, gynecologists and obstetricians, cell biologists, and everyone interested in learning more about female cancers, the Biology of Female Cancers offers a comprehensive, unique approach.
Author : Vijayalakshmi Kodati
Publisher :
ISBN 13 : 9789535105244
Total Pages : pages
Book Rating : 4.1/5 (52 download)
Download or read book Genetic Polymorphisms and Molecular Pathogenesis of Endometriosis written by Vijayalakshmi Kodati and published by . This book was released on 2012 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Spineanu Eugenia
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.2/5 (242 download)
Download or read book Endometrial Cancer written by Spineanu Eugenia and published by . This book was released on 2024-02-04 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Endometrial cancer, a malignancy originating from the inner lining of the uterus, stands as a significant health concern for women worldwide. This treatise offers an exhaustive exploration of endometrial cancer, weaving together historical context, cutting-edge research, and holistic approaches to both treatment and prevention. Designed for medical professionals, researchers, and patients alike, the content delves deep into the intricacies of the disease, ensuring a thorough understanding for all readers. The treatise begins by tracing the historical evolution of endometrial cancer research, highlighting key milestones and breakthroughs that have shaped our current understanding. This historical perspective sets the stage for a detailed examination of the global epidemiology and demographics of the disease, emphasizing its prevalence, risk factors, and the populations most affected. A deep dive into the anatomy and physiology of the endometrium provides readers with a foundational understanding of its structure, function, and the hormonal dynamics that influence its health. This section is particularly crucial, as it lays the groundwork for understanding the cellular and molecular mechanisms that drive cancer development and progression. The heart of the treatise delves into the pathogenesis of endometrial cancer. From DNA mutations and chromosomal aberrations to hormonal pathways and the tumor microenvironment, readers are guided through the complex interplay of factors that contribute to the disease. Special attention is given to the metabolic alterations observed in cancer cells and the role of the immune system in tumor progression. Risk factors and preventative measures are explored in depth, with a focus on both genetic predispositions and lifestyle factors. The treatise emphasizes the importance of a holistic approach to prevention, incorporating diet, environmental exposures, and integrative medicine practices. Diagnostic methods, from symptomatic manifestations to advanced imaging techniques and molecular diagnostic tools, are meticulously detailed. This comprehensive overview ensures that readers are well-equipped to understand the nuances of diagnosis, from initial symptoms to confirmatory tests. Treatment modalities form a significant portion of the treatise, covering surgical techniques, radiation, chemotherapy, and emerging therapies like immunotherapy and targeted treatments. The content underscores the importance of personalized medicine, tailoring treatments to the unique genetic and molecular profile of each patient. Post-treatment care and rehabilitation are addressed with equal rigor. From surveillance protocols to physical therapy and nutritional guidance, the treatise offers a roadmap for patients navigating life after treatment. Psychological support, integrative medicine, and mind-body practices are highlighted, emphasizing the importance of holistic care in recovery. Special topics, including endometrial cancer in younger women, aggressive variants, and management in immunocompromised patients, are explored in detail, ensuring that readers are equipped to handle even the most challenging cases. The treatise concludes with a forward-looking section on future research directions, from genomic studies to the potential of preventative vaccines. A glossary, patient resources, and a directory of clinical trials further enhance the utility of the treatise, making it an indispensable resource for anyone seeking a comprehensive understanding of endometrial cancer.
