Mathematical Modeling in Systems Biology

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Publisher : MIT Press
ISBN 13 : 0262545829
Total Pages : 423 pages
Book Rating : 4.2/5 (625 download)

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Book Synopsis Mathematical Modeling in Systems Biology by : Brian P. Ingalls

Download or read book Mathematical Modeling in Systems Biology written by Brian P. Ingalls and published by MIT Press. This book was released on 2022-06-07 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: An introduction to the mathematical concepts and techniques needed for the construction and analysis of models in molecular systems biology. Systems techniques are integral to current research in molecular cell biology, and system-level investigations are often accompanied by mathematical models. These models serve as working hypotheses: they help us to understand and predict the behavior of complex systems. This book offers an introduction to mathematical concepts and techniques needed for the construction and interpretation of models in molecular systems biology. It is accessible to upper-level undergraduate or graduate students in life science or engineering who have some familiarity with calculus, and will be a useful reference for researchers at all levels. The first four chapters cover the basics of mathematical modeling in molecular systems biology. The last four chapters address specific biological domains, treating modeling of metabolic networks, of signal transduction pathways, of gene regulatory networks, and of electrophysiology and neuronal action potentials. Chapters 3–8 end with optional sections that address more specialized modeling topics. Exercises, solvable with pen-and-paper calculations, appear throughout the text to encourage interaction with the mathematical techniques. More involved end-of-chapter problem sets require computational software. Appendixes provide a review of basic concepts of molecular biology, additional mathematical background material, and tutorials for two computational software packages (XPPAUT and MATLAB) that can be used for model simulation and analysis.

Mathematics for Life Science and Medicine

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Publisher : Springer Science & Business Media
ISBN 13 : 3540344268
Total Pages : 232 pages
Book Rating : 4.5/5 (43 download)

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Book Synopsis Mathematics for Life Science and Medicine by : Yasuhiro Takeuchi

Download or read book Mathematics for Life Science and Medicine written by Yasuhiro Takeuchi and published by Springer Science & Business Media. This book was released on 2007-01-25 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of this volume is to present and discuss the many rich properties of the dynamical systems that appear in life science and medicine. It provides a fascinating survey of the theory of dynamical systems in biology and medicine. Each chapter will serve to introduce students and scholars to the state-of-the-art in an exciting area, to present new results, and to inspire future contributions to mathematical modeling in life science and medicine.

An Introduction to the Mathematics of Medicine and Biology

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Publisher :
ISBN 13 :
Total Pages : 700 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis An Introduction to the Mathematics of Medicine and Biology by : J. G. Defares

Download or read book An Introduction to the Mathematics of Medicine and Biology written by J. G. Defares and published by . This book was released on 1973 with total page 700 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Introduction to Mathematical Oncology

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Publisher : CRC Press
ISBN 13 : 1584889918
Total Pages : 469 pages
Book Rating : 4.5/5 (848 download)

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Book Synopsis Introduction to Mathematical Oncology by : Yang Kuang

Download or read book Introduction to Mathematical Oncology written by Yang Kuang and published by CRC Press. This book was released on 2016-04-05 with total page 469 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction to Mathematical Oncology presents biologically well-motivated and mathematically tractable models that facilitate both a deep understanding of cancer biology and better cancer treatment designs. It covers the medical and biological background of the diseases, modeling issues, and existing methods and their limitations. The authors introduce mathematical and programming tools, along with analytical and numerical studies of the models. They also develop new mathematical tools and look to future improvements on dynamical models. After introducing the general theory of medicine and exploring how mathematics can be essential in its understanding, the text describes well-known, practical, and insightful mathematical models of avascular tumor growth and mathematically tractable treatment models based on ordinary differential equations. It continues the topic of avascular tumor growth in the context of partial differential equation models by incorporating the spatial structure and physiological structure, such as cell size. The book then focuses on the recent active multi-scale modeling efforts on prostate cancer growth and treatment dynamics. It also examines more mechanistically formulated models, including cell quota-based population growth models, with applications to real tumors and validation using clinical data. The remainder of the text presents abundant additional historical, biological, and medical background materials for advanced and specific treatment modeling efforts. Extensively classroom-tested in undergraduate and graduate courses, this self-contained book allows instructors to emphasize specific topics relevant to clinical cancer biology and treatment. It can be used in a variety of ways, including a single-semester undergraduate course, a more ambitious graduate course, or a full-year sequence on mathematical oncology.

An Introduction to Systems Biology

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Publisher : CRC Press
ISBN 13 : 1584886420
Total Pages : 324 pages
Book Rating : 4.5/5 (848 download)

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Book Synopsis An Introduction to Systems Biology by : Uri Alon

Download or read book An Introduction to Systems Biology written by Uri Alon and published by CRC Press. This book was released on 2006-07-07 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thorough and accessible, this book presents the design principles of biological systems, and highlights the recurring circuit elements that make up biological networks. It provides a simple mathematical framework which can be used to understand and even design biological circuits. The textavoids specialist terms, focusing instead on several well-studied biological systems that concisely demonstrate key principles. An Introduction to Systems Biology: Design Principles of Biological Circuits builds a solid foundation for the intuitive understanding of general principles. It encourages the reader to ask why a system is designed in a particular way and then proceeds to answer with simplified models.

An Introduction to Mathematics of Emerging Biomedical Imaging

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Publisher : Springer Science & Business Media
ISBN 13 : 3540795537
Total Pages : 198 pages
Book Rating : 4.5/5 (47 download)

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Book Synopsis An Introduction to Mathematics of Emerging Biomedical Imaging by : Habib Ammari

Download or read book An Introduction to Mathematics of Emerging Biomedical Imaging written by Habib Ammari and published by Springer Science & Business Media. This book was released on 2008-05-21 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomedical imaging is a fascinating research area to applied mathematicians. Challenging imaging problems arise and they often trigger the investigation of fundamental problems in various branches of mathematics. This is the first book to highlight the most recent mathematical developments in emerging biomedical imaging techniques. The main focus is on emerging multi-physics and multi-scales imaging approaches. For such promising techniques, it provides the basic mathematical concepts and tools for image reconstruction. Further improvements in these exciting imaging techniques require continued research in the mathematical sciences, a field that has contributed greatly to biomedical imaging and will continue to do so. The volume is suitable for a graduate-level course in applied mathematics and helps prepare the reader for a deeper understanding of research areas in biomedical imaging.

A Course in Mathematical Biology

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Publisher : SIAM
ISBN 13 : 0898718252
Total Pages : 307 pages
Book Rating : 4.8/5 (987 download)

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Book Synopsis A Course in Mathematical Biology by : Gerda de Vries

Download or read book A Course in Mathematical Biology written by Gerda de Vries and published by SIAM. This book was released on 2006-07-01 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the only book that teaches all aspects of modern mathematical modeling and that is specifically designed to introduce undergraduate students to problem solving in the context of biology. Included is an integrated package of theoretical modeling and analysis tools, computational modeling techniques, and parameter estimation and model validation methods, with a focus on integrating analytical and computational tools in the modeling of biological processes. Divided into three parts, it covers basic analytical modeling techniques; introduces computational tools used in the modeling of biological problems; and includes various problems from epidemiology, ecology, and physiology. All chapters include realistic biological examples, including many exercises related to biological questions. In addition, 25 open-ended research projects are provided, suitable for students. An accompanying Web site contains solutions and a tutorial for the implementation of the computational modeling techniques. Calculations can be done in modern computing languages such as Maple, Mathematica, and MATLAB?.

Introduction to Mathematics for Life Scientists

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Publisher : Springer Science & Business Media
ISBN 13 : 364296270X
Total Pages : 657 pages
Book Rating : 4.6/5 (429 download)

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Book Synopsis Introduction to Mathematics for Life Scientists by : E. Batschelet

Download or read book Introduction to Mathematics for Life Scientists written by E. Batschelet and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 657 pages. Available in PDF, EPUB and Kindle. Book excerpt: A few decades ago mathematics played a modest role in life sciences. Today, however, a great variety of mathematical methods is applied in biology and medicine. Practically every mathematical procedure that is useful in physics, chemistry, engineering, and economics has also found an important application in the life sciences. The past and present training of life scientists does by no means reflect this development. However, the impact ofthe fast growing number of applications of mathematical methods makes it indispensable that students in the life sciences are offered a basic training in mathematics, both on the undergraduate and the graduate level. This book is primarily designed as a textbook for an introductory course. Life scientists may also use it as a reference to find mathematical methods suitable to their research problems. Moreover, the book should be appropriate for self-teaching. It will also be a guide for teachers. Numerous references are included to assist the reader in his search for the pertinent literature.

Modeling and Simulation in Medicine and the Life Sciences

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Publisher : Springer Science & Business Media
ISBN 13 : 0387215719
Total Pages : 362 pages
Book Rating : 4.3/5 (872 download)

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Book Synopsis Modeling and Simulation in Medicine and the Life Sciences by : Frank C. Hoppensteadt

Download or read book Modeling and Simulation in Medicine and the Life Sciences written by Frank C. Hoppensteadt and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: The result of lectures given by the authors at New York University, the University of Utah, and Michigan State University, the material is written for students who have had only one term of calculus, but it contains material that can be used in modeling courses in applied mathematics at all levels through early graduate courses. Numerous exercises are given as well as solutions to selected exercises, so as to lead readers to discover interesting extensions of that material. Throughout, illustrations depict physiological processes, population biology phenomena, corresponding models, and the results of computer simulations. Topics covered range from population phenomena to demographics, genetics, epidemics and dispersal; in physiological processes, including the circulation, gas exchange in the lungs, control of cell volume, the renal counter-current multiplier mechanism, and muscle mechanics; to mechanisms of neural control. Each chapter is graded in difficulty, so a reading of the first parts of each provides an elementary introduction to the processes and their models.

Calculations for Molecular Biology and Biotechnology

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Publisher : Academic Press
ISBN 13 : 012375691X
Total Pages : 520 pages
Book Rating : 4.1/5 (237 download)

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Book Synopsis Calculations for Molecular Biology and Biotechnology by : Frank H. Stephenson

Download or read book Calculations for Molecular Biology and Biotechnology written by Frank H. Stephenson and published by Academic Press. This book was released on 2010-07-30 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: Calculations for Molecular Biology and Biotechnology: A Guide to Mathematics in the Laboratory, Second Edition, provides an introduction to the myriad of laboratory calculations used in molecular biology and biotechnology. The book begins by discussing the use of scientific notation and metric prefixes, which require the use of exponents and an understanding of significant digits. It explains the mathematics involved in making solutions; the characteristics of cell growth; the multiplicity of infection; and the quantification of nucleic acids. It includes chapters that deal with the mathematics involved in the use of radioisotopes in nucleic acid research; the synthesis of oligonucleotides; the polymerase chain reaction (PCR) method; and the development of recombinant DNA technology. Protein quantification and the assessment of protein activity are also discussed, along with the centrifugation method and applications of PCR in forensics and paternity testing. - Topics range from basic scientific notations to complex subjects like nucleic acid chemistry and recombinant DNA technology - Each chapter includes a brief explanation of the concept and covers necessary definitions, theory and rationale for each type of calculation - Recent applications of the procedures and computations in clinical, academic, industrial and basic research laboratories are cited throughout the text New to this Edition: - Updated and increased coverage of real time PCR and the mathematics used to measure gene expression - More sample problems in every chapter for readers to practice concepts

Mathematical Biology II

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Publisher : Springer Science & Business Media
ISBN 13 : 0387952284
Total Pages : 834 pages
Book Rating : 4.3/5 (879 download)

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Book Synopsis Mathematical Biology II by : James D. Murray

Download or read book Mathematical Biology II written by James D. Murray and published by Springer Science & Business Media. This book was released on 2011-02-15 with total page 834 pages. Available in PDF, EPUB and Kindle. Book excerpt: This richly illustrated third edition provides a thorough training in practical mathematical biology and shows how exciting mathematical challenges can arise from a genuinely interdisciplinary involvement with the biosciences. It has been extensively updated and extended to cover much of the growth of mathematical biology. From the reviews: ""This book, a classical text in mathematical biology, cleverly combines mathematical tools with subject area sciences."--SHORT BOOK REVIEWS

Mathematical Models in Biology

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Publisher : Cambridge University Press
ISBN 13 : 9780521525862
Total Pages : 388 pages
Book Rating : 4.5/5 (258 download)

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Book Synopsis Mathematical Models in Biology by : Elizabeth Spencer Allman

Download or read book Mathematical Models in Biology written by Elizabeth Spencer Allman and published by Cambridge University Press. This book was released on 2004 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: This introductory textbook on mathematical biology focuses on discrete models across a variety of biological subdisciplines. Biological topics treated include linear and non-linear models of populations, Markov models of molecular evolution, phylogenetic tree construction, genetics, and infectious disease models. The coverage of models of molecular evolution and phylogenetic tree construction from DNA sequence data is unique among books at this level. Computer investigations with MATLAB are incorporated throughout, in both exercises and more extensive projects, to give readers hands-on experience with the mathematical models developed. MATLAB programs accompany the text. Mathematical tools, such as matrix algebra, eigenvector analysis, and basic probability, are motivated by biological models and given self-contained developments, so that mathematical prerequisites are minimal.

Mathematical Biology

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Publisher : Springer Science & Business Media
ISBN 13 : 0387224378
Total Pages : 551 pages
Book Rating : 4.3/5 (872 download)

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Book Synopsis Mathematical Biology by : James D. Murray

Download or read book Mathematical Biology written by James D. Murray and published by Springer Science & Business Media. This book was released on 2007-06-12 with total page 551 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mathematical Biology is a richly illustrated textbook in an exciting and fast growing field. Providing an in-depth look at the practical use of math modeling, it features exercises throughout that are drawn from a variety of bioscientific disciplines - population biology, developmental biology, physiology, epidemiology, and evolution, among others. It maintains a consistent level throughout so that graduate students can use it to gain a foothold into this dynamic research area.

Mathematics for the Life Sciences

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Publisher : Princeton University Press
ISBN 13 : 0691150729
Total Pages : 630 pages
Book Rating : 4.6/5 (911 download)

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Book Synopsis Mathematics for the Life Sciences by : Erin N. Bodine

Download or read book Mathematics for the Life Sciences written by Erin N. Bodine and published by Princeton University Press. This book was released on 2014-08-17 with total page 630 pages. Available in PDF, EPUB and Kindle. Book excerpt: An accessible undergraduate textbook on the essential math concepts used in the life sciences The life sciences deal with a vast array of problems at different spatial, temporal, and organizational scales. The mathematics necessary to describe, model, and analyze these problems is similarly diverse, incorporating quantitative techniques that are rarely taught in standard undergraduate courses. This textbook provides an accessible introduction to these critical mathematical concepts, linking them to biological observation and theory while also presenting the computational tools needed to address problems not readily investigated using mathematics alone. Proven in the classroom and requiring only a background in high school math, Mathematics for the Life Sciences doesn't just focus on calculus as do most other textbooks on the subject. It covers deterministic methods and those that incorporate uncertainty, problems in discrete and continuous time, probability, graphing and data analysis, matrix modeling, difference equations, differential equations, and much more. The book uses MATLAB throughout, explaining how to use it, write code, and connect models to data in examples chosen from across the life sciences. Provides undergraduate life science students with a succinct overview of major mathematical concepts that are essential for modern biology Covers all the major quantitative concepts that national reports have identified as the ideal components of an entry-level course for life science students Provides good background for the MCAT, which now includes data-based and statistical reasoning Explicitly links data and math modeling Includes end-of-chapter homework problems, end-of-unit student projects, and select answers to homework problems Uses MATLAB throughout, and MATLAB m-files with an R supplement are available online Prepares students to read with comprehension the growing quantitative literature across the life sciences A solutions manual for professors and an illustration package is available

Introduction to Physics in Modern Medicine

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Publisher : CRC Press
ISBN 13 : 9780415301718
Total Pages : 358 pages
Book Rating : 4.3/5 (17 download)

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Book Synopsis Introduction to Physics in Modern Medicine by : Suzanne Amador Kane

Download or read book Introduction to Physics in Modern Medicine written by Suzanne Amador Kane and published by CRC Press. This book was released on 2002-11-28 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: The medical applications of physics are not typically covered in introductory physics courses. Introduction to Physics in Modern Medicine fills that gap by explaining the physical principles behind technologies such as surgical lasers or computed tomography (CT or CAT) scanners. Each chapter includes a short explanation of the scientific background, making this book highly accessible to those without an advanced knowledge of physics. It is intended for medicine and health studies students who need an elementary background in physics, but it also serves well as a non-mathematical introduction to applied physics for undergraduate students in physics, engineering, and other disciplines.

Modeling Life

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Publisher : Springer
ISBN 13 : 3319597310
Total Pages : 456 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Modeling Life by : Alan Garfinkel

Download or read book Modeling Life written by Alan Garfinkel and published by Springer. This book was released on 2017-09-06 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book develops the mathematical tools essential for students in the life sciences to describe interacting systems and predict their behavior. From predator-prey populations in an ecosystem, to hormone regulation within the body, the natural world abounds in dynamical systems that affect us profoundly. Complex feedback relations and counter-intuitive responses are common in nature; this book develops the quantitative skills needed to explore these interactions. Differential equations are the natural mathematical tool for quantifying change, and are the driving force throughout this book. The use of Euler’s method makes nonlinear examples tractable and accessible to a broad spectrum of early-stage undergraduates, thus providing a practical alternative to the procedural approach of a traditional Calculus curriculum. Tools are developed within numerous, relevant examples, with an emphasis on the construction, evaluation, and interpretation of mathematical models throughout. Encountering these concepts in context, students learn not only quantitative techniques, but how to bridge between biological and mathematical ways of thinking. Examples range broadly, exploring the dynamics of neurons and the immune system, through to population dynamics and the Google PageRank algorithm. Each scenario relies only on an interest in the natural world; no biological expertise is assumed of student or instructor. Building on a single prerequisite of Precalculus, the book suits a two-quarter sequence for first or second year undergraduates, and meets the mathematical requirements of medical school entry. The later material provides opportunities for more advanced students in both mathematics and life sciences to revisit theoretical knowledge in a rich, real-world framework. In all cases, the focus is clear: how does the math help us understand the science?

Introduction to Mathematical Biology

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Publisher : Springer
ISBN 13 : 3319296388
Total Pages : 174 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Introduction to Mathematical Biology by : Ching Shan Chou

Download or read book Introduction to Mathematical Biology written by Ching Shan Chou and published by Springer. This book was released on 2016-04-27 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is based on a one semester course that the authors have been teaching for several years, and includes two sets of case studies. The first includes chemostat models, predator-prey interaction, competition among species, the spread of infectious diseases, and oscillations arising from bifurcations. In developing these topics, readers will also be introduced to the basic theory of ordinary differential equations, and how to work with MATLAB without having any prior programming experience. The second set of case studies were adapted from recent and current research papers to the level of the students. Topics have been selected based on public health interest. This includes the risk of atherosclerosis associated with high cholesterol levels, cancer and immune interactions, cancer therapy, and tuberculosis. Readers will experience how mathematical models and their numerical simulations can provide explanations that guide biological and biomedical research. Considered to be the undergraduate companion to the more advanced book "Mathematical Modeling of Biological Processes" (A. Friedman, C.-Y. Kao, Springer – 2014), this book is geared towards undergraduate students with little background in mathematics and no biological background.