Amyotrophic Lateral Sclerosis In Veterans

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Amyotrophic Lateral Sclerosis in Veterans

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309102545
Total Pages : 62 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Amyotrophic Lateral Sclerosis in Veterans by : Institute of Medicine

Download or read book Amyotrophic Lateral Sclerosis in Veterans written by Institute of Medicine and published by National Academies Press. This book was released on 2006-11-27 with total page 62 pages. Available in PDF, EPUB and Kindle. Book excerpt: Amyotrophic lateral sclerosis (ALS) our Lou Gehrig's disease is a fatal, mostly non-familial disease that affects the nervous system of humans by causing the degeneration of nerve cells in the brain and spinal cord. The degeneration halts communication between the nervous system and voluntary muscles in the body. This leads to muscle paralysis and eventually the muscles that aid in breathing are affect; causing respiration to fail. The disease, which affects 20,000-30,000 men and women in the United States at any given time, has no effective treatment; most people with ALS die from respiratory failure within 5 years of the onset of symptoms. Recent epidemiologic studies report an association between the development of ALS and prior service in the U.S. military. The studies evaluated either veterans of the 1991 Persian Gulf War or veterans who served in the military in the period 1910-1982. Due to these findings, the Department of Veterans Affairs (VA) asked the National Academies to conduct an assessment of the potential relationship between military service and the later development of ALS. The project was assigned to the Institute of Medicine (IOM), which appointed a committee and gave it the task of evaluating the scientific literature on ALS in veterans. The committee began its work by identifying medical and scientific literature on ALS. PubMed, a database created and managed by the National Library of Medicine. Amyotrophic Lateral Sclerosis in Veterans; Review of the Scientific Literature presents the findings of this committee. The committee reviewed, evaluated, and summarized the scientific literature on ALS in veterans, composed primarily of peer-reviewed, published literature. This report includes the recommendations of the committee.

Occurrence of Amyotropic Lateral Sclerosis Among Gulf War Veterans

Author :
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (946 download)

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Book Synopsis Occurrence of Amyotropic Lateral Sclerosis Among Gulf War Veterans by :

Download or read book Occurrence of Amyotropic Lateral Sclerosis Among Gulf War Veterans written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Context. A nation wide epidemiological investigation was undertaken in response to Gulf War Veterans' concerns of high rates of amyotrophic lateral sclerosis (ALS). To determine if Gulf War veterans have an elevated rate of ALS.

Secondary Analysis of Amyotrophic Lateral Sclerosis Data from U.S. Veterans on Guam

Author : Scott Jordan Hall
Publisher :
ISBN 13 :
Total Pages : 138 pages
Book Rating : 4.:/5 (672 download)

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Book Synopsis Secondary Analysis of Amyotrophic Lateral Sclerosis Data from U.S. Veterans on Guam by : Scott Jordan Hall

Download or read book Secondary Analysis of Amyotrophic Lateral Sclerosis Data from U.S. Veterans on Guam written by Scott Jordan Hall and published by . This book was released on 2003 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Neurological and Neuropsychiatric Disorders Affecting Military Personnel and Veterans

Author : Mary Jo Pugh
Publisher : Frontiers Media SA
ISBN 13 : 2832546560
Total Pages : 188 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Neurological and Neuropsychiatric Disorders Affecting Military Personnel and Veterans by : Mary Jo Pugh

Download or read book Neurological and Neuropsychiatric Disorders Affecting Military Personnel and Veterans written by Mary Jo Pugh and published by Frontiers Media SA. This book was released on 2024-03-20 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: Active military personnel and Veterans of the military face unique neurologic and neuropsychiatric challenges unique to this population compared to the public. The military and Veteran population have faced traumatic experiences that lead to both physical and mental consequences. Amongst the important challenges unique to this population include traumatic brain injury, increased risk of neurological disorders such as dementia and stroke, and comorbid neuropsychiatric conditions. Unfortunately, many of these challenges also have a negative feedback loop such as brain injuries leading to post-traumatic stress order, which can increase risk of Alzheimer’s Dementia. Unfortunately, there are many gaps in knowledge to understand the unique challenges this population faces.There are many opportunities to improve our understanding of these challenges that military personnel and Veterans face. The goal of this Research Topic is to shine a light and improve understanding of these challenges. We aim to collect knowledge from the global network of researchers working on topics related to “Neurological and Neuropsychiatric disorders affecting military personnel and Veterans.” There are currently many gaps in the diagnosis, prevention, and treatment of conditions that affect this population disproportionately. This collection of work in the Frontiers in Neurology will give authors the opportunity to share with the global scientific community important research findings that address these gaps.For this collection, we are looking for submissions with topics that specifically address the unique challenges affecting military personnel and Veterans with Neurologic and Neuropsychiatric disorders.

Morbidity of Vietnam Veterans

Author :
Publisher :
ISBN 13 : 9781740241113
Total Pages : 40 pages
Book Rating : 4.2/5 (411 download)

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Book Synopsis Morbidity of Vietnam Veterans by :

Download or read book Morbidity of Vietnam Veterans written by and published by . This book was released on 2001 with total page 40 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Commonwealth Department of Veterans' Affairs" -- Cover

Prospective Study of ALS Mortality Among World War II, Korea, and Vietnam Veterans

Author :
Publisher :
ISBN 13 :
Total Pages : 7 pages
Book Rating : 4.:/5 (227 download)

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Book Synopsis Prospective Study of ALS Mortality Among World War II, Korea, and Vietnam Veterans by :

Download or read book Prospective Study of ALS Mortality Among World War II, Korea, and Vietnam Veterans written by and published by . This book was released on 2006 with total page 7 pages. Available in PDF, EPUB and Kindle. Book excerpt: The authors prospectively assessed the association between Amyotrophic Lateral Sclerosis (ALS) mortality and self-reported military service in the American Cancer Society's Cancer Prevention Study II (CPS II) cohort, a cohort that includes over 500,000 men who were surveyed by questionnaire in 1982. ALS mortality was assessed via linkage with the National Death Index. Their original analyses included ALS deaths (n = 280) up to 1998. They have now extended the follow-up to 2002 (ALS deaths = 513). Mantel-Haenszel relative risks (RR) adjusted for age and smoking were calculated and Cox proportional hazards models stratified on single year of age were used when adjusting for additional variables. Men who served in the military (69% of their population) had a significantly increased ALS mortality (RR = 1.5) compared to those who did not serve. The increase in ALS mortality was similar among men who served in the Army or National Guard (RR = 1.5), Navy (RR = 1.7), or Air Force (RR = 1.5). This increased risk of ALS appeared largely independent of branch of service, years of service, number of major conflicts during service, and war periods during service (i.e., World War II, the Korean War, and the Vietnam War). The project will continue as planned. The authors will extend the follow-up and examine the possible role of vitamin E supplements in prevention.

Gulf War Exposures

Author : United States. Congress. House. Committee on Veterans' Affairs. Subcommittee on Health
Publisher :
ISBN 13 :
Total Pages : 148 pages
Book Rating : 4.0/5 ( download)

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Book Synopsis Gulf War Exposures by : United States. Congress. House. Committee on Veterans' Affairs. Subcommittee on Health

Download or read book Gulf War Exposures written by United States. Congress. House. Committee on Veterans' Affairs. Subcommittee on Health and published by . This book was released on 2008 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Veterans and Agent Orange

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309477166
Total Pages : 739 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Veterans and Agent Orange by : National Academies of Sciences, Engineering, and Medicine

Download or read book Veterans and Agent Orange written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2019-01-20 with total page 739 pages. Available in PDF, EPUB and Kindle. Book excerpt: From 1962 to 1971, the U.S. military sprayed herbicides over Vietnam to strip the thick jungle canopy that could conceal opposition forces, to destroy crops that those forces might depend on, and to clear tall grasses and bushes from the perimeters of US base camps and outlying fire-support bases. Mixtures of 2,4-dichlorophenoxyacetic acid (2,4-D), 2,4,5-trichlorophenoxyacetic acid (2,4,5-T), picloram, and cacodylic acid made up the bulk of the herbicides sprayed. The main chemical mixture sprayed was Agent Orange, a 50:50 mixture of 2,4-D and 2,4,5-T. At the time of the spraying, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), the most toxic form of dioxin, was an unintended contaminant generated during the production of 2,4,5-T and so was present in Agent Orange and some other formulations sprayed in Vietnam. Because of complaints from returning Vietnam veterans about their own health and that of their children combined with emerging toxicologic evidence of adverse effects of phenoxy herbicides and TCDD, the National Academies of Sciences, Engineering, and Medicine was asked to perform a comprehensive evaluation of scientific and medical information regarding the health effects of exposure to Agent Orange, other herbicides used in Vietnam, and the various components of those herbicides, including TCDD. Updated evaluations were conducted every two years to review newly available literature and draw conclusions from the overall evidence. Veterans and Agent Orange: Update 11 (2018) examines peer-reviewed scientific reports concerning associations between various health outcomes and exposure to TCDD and other chemicals in the herbicides used in Vietnam that were published between September 30, 2014, and December 31, 2017, and integrates this information with the previously established evidence database.

The Current Population Survey

Author : United States. Bureau of the Census
Publisher :
ISBN 13 :
Total Pages : 190 pages
Book Rating : 4.3/5 (121 download)

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Book Synopsis The Current Population Survey by : United States. Bureau of the Census

Download or read book The Current Population Survey written by United States. Bureau of the Census and published by . This book was released on 1978 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Biomarkers for Amyotrophic Lateral Sclerosis in Active Duty Military (BALSAM).

Author :
Publisher :
ISBN 13 :
Total Pages : 56 pages
Book Rating : 4.:/5 (495 download)

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Book Synopsis Biomarkers for Amyotrophic Lateral Sclerosis in Active Duty Military (BALSAM). by :

Download or read book Biomarkers for Amyotrophic Lateral Sclerosis in Active Duty Military (BALSAM). written by and published by . This book was released on 2009 with total page 56 pages. Available in PDF, EPUB and Kindle. Book excerpt: To compare serum samples from individuals diagnosed with amyotrophic lateral sclerosis (ALS) to serum samples from matched individuals who did not develop ALS. In this study we aim to identify candidate serum biomarkers that are unique for ALS and identify a subset of diagnostic serum biomarkers for early detection of ALS prior to the appearance of overt symptoms. Scope: The significance of a positive identification of protein biomarkers for ALS is indisputably great. However, to date no validated clinically relevant biomarkers have been found to allow a more specific diagnosis of ALS at an earlier stage. Previous efforts to identify ALS associated biomarkers have often focused on the identification of genes and proteins characteristic for familial ALS, yet validated biomarkers for sporadic ALS, which accounts for as much as 90-95% of all ALS cases, have yet to be identified. Major Findings: None at this time. Progress: This study received USAMRMC HSSRB approval on 15 Jan 2007. The Durham VA and Univ. of Cincinnati IRB protocols have also been approved. Durham VA IRB began consenting the VA ALS registry members for this study. Model system 2-D gel and mass spectrometry studies have been conducted to develop improved techniques for biomarker identification.

Gulf War Review

Author :
Publisher :
ISBN 13 :
Total Pages : 80 pages
Book Rating : 4.:/5 (8 download)

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Book Synopsis Gulf War Review by :

Download or read book Gulf War Review written by and published by . This book was released on 2000-10 with total page 80 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Veterans at Risk

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 030904832X
Total Pages : 448 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Veterans at Risk by : Institute of Medicine

Download or read book Veterans at Risk written by Institute of Medicine and published by National Academies Press. This book was released on 1993-02-01 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recently, World War II veterans have come forward to claim compensation for health effects they say were caused by their participation in chemical warfare experiments. In response, the Veterans Administration asked the Institute of Medicine to study the issue. Based on a literature review and personal testimony from more than 250 affected veterans, this new volume discusses in detail the development and chemistry of mustard agents and Lewisite followed by interesting and informative discussions about these substances and their possible connection to a range of health problems, from cancer to reproductive disorders. The volume also offers an often chilling historical examination of the use of volunteers in chemical warfare experiments by the U.S. militaryâ€"what the then-young soldiers were told prior to the experiments, how they were "encouraged" to remain in the program, and how they were treated afterward. This comprehensive and controversial book will be of importance to policymakers and legislators, military and civilian planners, officials at the Department of Veterans Affairs, military historians, and researchers.

Bills Providing Benefits for Service-connected Disabled Veterans and Their Dependents

Author : United States. Congress. House. Committee on Veterans' Affairs. Subcommittee on Compensation and Pensions
Publisher :
ISBN 13 :
Total Pages : 116 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Bills Providing Benefits for Service-connected Disabled Veterans and Their Dependents by : United States. Congress. House. Committee on Veterans' Affairs. Subcommittee on Compensation and Pensions

Download or read book Bills Providing Benefits for Service-connected Disabled Veterans and Their Dependents written by United States. Congress. House. Committee on Veterans' Affairs. Subcommittee on Compensation and Pensions and published by . This book was released on 1953 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Veterans and Agent Orange

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309380669
Total Pages : 1115 pages
Book Rating : 4.3/5 (93 download)

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Book Synopsis Veterans and Agent Orange by : National Academies of Sciences, Engineering, and Medicine

Download or read book Veterans and Agent Orange written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2016-04-29 with total page 1115 pages. Available in PDF, EPUB and Kindle. Book excerpt: From 1962 to 1971, the US military sprayed herbicides over Vietnam to strip the thick jungle canopy that could conceal opposition forces, to destroy crops that those forces might depend on, and to clear tall grasses and bushes from the perimeters of US base camps and outlying fire-support bases. Mixtures of 2,4-dichlorophenoxyacetic acid (2,4-D), 2,4,5-trichlorophenoxyacetic acid (2,4,5-T), picloram, and cacodylic acid made up the bulk of the herbicides sprayed. The main chemical mixture sprayed was Agent Orange, a 50:50 mixture of 2,4-D and 2,4,5-T. At the time of the spraying, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), the most toxic form of dioxin, was an unintended contaminant generated during the production of 2,4,5-T and so was present in Agent Orange and some other formulations sprayed in Vietnam. Because of complaints from returning Vietnam veterans about their own health and that of their children combined with emerging toxicologic evidence of adverse effects of phenoxy herbicides and TCDD, the National Academy of Sciences was asked to perform a comprehensive evaluation of scientific and medical information regarding the health effects of exposure to Agent Orange, other herbicides used in Vietnam, and the various components of those herbicides, including TCDD. Updated evaluations were conducted every two years to review newly available literature and draw conclusions from the overall evidence. Veterans and Agent Orange: Update 2014 is a cumulative report of the series thus far.

Palliative Care in Amyotrophic Lateral Sclerosis

Author : David Oliver
Publisher : OUP Oxford
ISBN 13 : 0191509507
Total Pages : 353 pages
Book Rating : 4.1/5 (915 download)

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Book Synopsis Palliative Care in Amyotrophic Lateral Sclerosis by : David Oliver

Download or read book Palliative Care in Amyotrophic Lateral Sclerosis written by David Oliver and published by OUP Oxford. This book was released on 2014-03-20 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: Amytrophic Lateral Sclerosis (ALS or motor neurone disease) is a progressive neurodegenerative disease that can cause profound suffering for both the patient and their family. Whilst new treatments for ALS are being developed, these are not curative and offer only the potential to slow its progression. Palliative care must therefore be integral to the clinical approach to the disease. Palliative Care in Amyotrophic Lateral Sclerosis: From diagnosis to bereavement reflects the wide scope of this care; it must cover not just the terminal phase, but support the patient and their family from the onset of the disease. Both the multidisciplinary palliative care team and the neurology team are essential in providing a high standard of care and allowing quality of life (both patient and carer) to be maintained. Clear guidelines are provided to address care throughout the disease process. Control of symptoms is covered alongside the psychosocial care of patients and their families. Case studies are used to emphasise the complexity of the care needs and involvement of the patient and family, culminating in discussion of bereavement. Different models of care are explored, and this new edition utilizes the increase in both the evidence-base and available literature on the subject. New topics discussed include complementary therapies, personal and family experiences of ALS, new genetics research, and updated guidelines for patient care, to ensure this new edition remains the essential guide to palliative care in ALS.

Long-Term Health Consequences of Exposure to Burn Pits in Iraq and Afghanistan

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 030921758X
Total Pages : 192 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis Long-Term Health Consequences of Exposure to Burn Pits in Iraq and Afghanistan by : Institute of Medicine

Download or read book Long-Term Health Consequences of Exposure to Burn Pits in Iraq and Afghanistan written by Institute of Medicine and published by National Academies Press. This book was released on 2011-10-31 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many veterans returning from the conflicts in Iraq and Afghanistan have health problems they believe are related to their exposure to the smoke from the burning of waste in open-air "burn pits" on military bases. Particular controversy surrounds the burn pit used to dispose of solid waste at Joint Base Balad in Iraq, which burned up to 200 tons of waste per day in 2007. The Department of Veterans Affairs asked the IOM to form a committee to determine the long-term health effects from exposure to these burn pits. Insufficient evidence prevented the IOM committee from developing firm conclusions. This report, therefore, recommends that, along with more efficient data-gathering methods, a study be conducted that would evaluate the health status of service members from their time of deployment over many years to determine their incidence of chronic diseases.

Multiple Sclerosis

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309072859
Total Pages : 457 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Multiple Sclerosis by : Institute of Medicine

Download or read book Multiple Sclerosis written by Institute of Medicine and published by National Academies Press. This book was released on 2001-08-10 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multiple sclerosis is a chronic and often disabling disease of the nervous system, affecting about 1 million people worldwide. Even though it has been known for over a hundred years, no cause or cure has yet been discovered-but now there is hope. New therapies have been shown to slow the disease progress in some patients, and the pace of discoveries about the cellular machinery of the brain and spinal cord has accelerated. This book presents a comprehensive overview of multiple sclerosis today, as researchers seek to understand its processes, develop therapies that will slow or halt the disease and perhaps repair damage, offer relief for specific symptoms, and improve the abilities of MS patients to function in their daily lives. The panel reviews existing knowledge and identifies key research questions, focusing on: Research strategies that have the greatest potential to understand the biological mechanisms of recovery and to translate findings into specific strategies for therapy. How people adapt to MS and the research needed to improve the lives of people with MS. Management of disease symptoms (cognitive impairment, depression, spasticity, vision problems, and others). The committee also discusses ways to build and financially support the MS research enterprise, including a look at challenges inherent in designing clinical trials. This book will be important to MS researchers, research funders, health care advocates for MS research and treatment, and interested patients and their families.