Amélioration des rendements de production pharmaceutique de formes séches, de la fabrication au conditionnement

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ISBN 13 :
Total Pages : 114 pages
Book Rating : 4.:/5 (973 download)

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Book Synopsis Amélioration des rendements de production pharmaceutique de formes séches, de la fabrication au conditionnement by : Bérénice Cadène

Download or read book Amélioration des rendements de production pharmaceutique de formes séches, de la fabrication au conditionnement written by Bérénice Cadène and published by . This book was released on 2016 with total page 114 pages. Available in PDF, EPUB and Kindle. Book excerpt: C’est dans un contexte dynamique et concurrentiel que le site de production Sanofi Lisieux évolue depuis près de 50 ans. Le maintien de son leadership dans la production du Doliprane®, formes sèches et suppositoires, est le garant d’une image forte du groupe Sanofi, 2e producteur pharmaceutique européen et 5e mondial. Afin de satisfaire la constante augmentation de la demande du marché, tout en maintenant un coût de production compétitif, le site de Lisieux s’est donné pour objectif un gain de un point de rendement pour l’année 2016. Ce gain de performance pourra financer de nouvelles capacités de production et ainsi optimiser sa réactivité face à la demande. Cette étude a pour objectif de diminuer le volume de pertes de produits finis et semi-ouvrés. Pour ce faire il s’agit de mettre en place un procédé de recyclage des rejets en routine, tout en respectant la qualité et la sécurité des médicaments produits. L’introduction de valeurs seuils d’alerte doit permettre d’augmenter la réactivité des équipes de production et de maintenance. Enfin, le suivi des indicateurs clés de performance doit garantir la maîtrise de l’efficience du procédé.

Amélioration des calculs de rendement et des pratiques de reconciliation au conditionnement de formes sèches

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ISBN 13 :
Total Pages : 160 pages
Book Rating : 4.:/5 (81 download)

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Book Synopsis Amélioration des calculs de rendement et des pratiques de reconciliation au conditionnement de formes sèches by : Lina Kandil

Download or read book Amélioration des calculs de rendement et des pratiques de reconciliation au conditionnement de formes sèches written by Lina Kandil and published by . This book was released on 2012 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dans le cadre d’une fiabilisation des pratiques au sein d’un site de production pharmaceutique de formes sèches, un projet a été mené afin d’améliorer l’utilisation d’indicateurs quantitatifs que sont les rendements et la réconciliation. Cette thèse décrit les pratiques existantes, leur analyse, les méthodes suivies pour améliorer ces pratiques et leur mise en place.

TENTATIVE D'OPTIMISATION DES RENDEMENTS DE FABRICATION DANS L'INDUSTRIE PHARMACEUTIQUE

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ISBN 13 :
Total Pages : 220 pages
Book Rating : 4.:/5 (49 download)

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Book Synopsis TENTATIVE D'OPTIMISATION DES RENDEMENTS DE FABRICATION DANS L'INDUSTRIE PHARMACEUTIQUE by : PIERRE-OLIVIER.. KALFON

Download or read book TENTATIVE D'OPTIMISATION DES RENDEMENTS DE FABRICATION DANS L'INDUSTRIE PHARMACEUTIQUE written by PIERRE-OLIVIER.. KALFON and published by . This book was released on 1984 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Amélioration de la performance des lignes de conditionnement dans un atelier de formes semi-solides

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Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (138 download)

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Book Synopsis Amélioration de la performance des lignes de conditionnement dans un atelier de formes semi-solides by : Marc Melin

Download or read book Amélioration de la performance des lignes de conditionnement dans un atelier de formes semi-solides written by Marc Melin and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: L'industrie pharmaceutique, longtemps riche et prospère grâce aux blockbusters qui ont soutenu ses résultats, voit ses bénéfices commencer à diminuer. Les coûts de R&D et de production augmentent en raison des progrès de la biotechnologie, des processus de commercialisation difficiles et chronophages, de la concurrence des génériques, des réglementations strictes et de l'émergence de produits contrefaits. Dans ce contexte, le lean management, jusqu'alors cousin faible de l'industrie, devient une arme stratégique de maintien des profits.

Suivi des rejets séchés sur ligne de conditionnement

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Publisher :
ISBN 13 :
Total Pages : 188 pages
Book Rating : 4.:/5 (14 download)

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Book Synopsis Suivi des rejets séchés sur ligne de conditionnement by : Thoscany Lekeumo

Download or read book Suivi des rejets séchés sur ligne de conditionnement written by Thoscany Lekeumo and published by . This book was released on 2018 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: C'est dans un contexte concurrentiel et dynamique que le groupe pharmaceutique SANOFI évolue depuis plusieurs années. Son site de production de Lisieux lui permet de maintenir sa place de leader dans la production du Doliprane@ formes sèches et suppositoires. Pour avoir relevé un taux de rejet anormalement élevé au niveau de ses lignes de conditionnement, et dans l'optique d'améliorer la gestion des réconciliations de matières en fin de lot, le site de Lisieux a proposé de mener un projet visant à améliorer les rendements de production et les procédures de réconciliations faites au cours de l'étape du conditionnement. Ce travail a eu pour but de concevoir une méthode permettant de mesurer la quantité de rejets sur les lignes de conditionnement, de déterminer les points majeurs à modifier et les actions à mettre en place afin de diminuer le volume de ces pertes de matières. Toute cette étude a été faite dans le respect de la qualité des médicaments produits, et donc de la sécurité des patients, en s'appuyant sur la démarche DMAIC de résolution de problèmes. La mission a été menée à travers plusieurs phases : La description du projet, la mise en place d'une méthodologie précise de mesures du taux de rejet, l'analyse des causes de défaillances et proposition des solutions d'améliorations au niveau des lignes de conditionnement. La mise en place du projet a permis de mettre en avant les manquements de la méthode actuelle de quantification des rejets, puis, par une approche de mesure différente, de présenter des résultats beaucoup plus précis permettant de déterminer la quantité de rejets. Une analyse des causes de rejets a ensuite permis de mettre en place des mesures d'améliorations afin de faire évoluer le rendement au conditionnement.

Ethnopharmacologie, sources, méthodes, objectifs

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Publisher : IRD Editions
ISBN 13 : 9782709910385
Total Pages : 502 pages
Book Rating : 4.9/5 (13 download)

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Book Synopsis Ethnopharmacologie, sources, méthodes, objectifs by : Jacques Fleurentin

Download or read book Ethnopharmacologie, sources, méthodes, objectifs written by Jacques Fleurentin and published by IRD Editions. This book was released on 1991 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Doing Business 2020

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Publisher : World Bank Publications
ISBN 13 : 1464814414
Total Pages : 241 pages
Book Rating : 4.4/5 (648 download)

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Book Synopsis Doing Business 2020 by : World Bank

Download or read book Doing Business 2020 written by World Bank and published by World Bank Publications. This book was released on 2019-11-21 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: Seventeen in a series of annual reports comparing business regulation in 190 economies, Doing Business 2020 measures aspects of regulation affecting 10 areas of everyday business activity.

Faecal Sludge Management

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Publisher : IWA Publishing
ISBN 13 : 1780404735
Total Pages : 428 pages
Book Rating : 4.7/5 (84 download)

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Book Synopsis Faecal Sludge Management by : Linda Strande

Download or read book Faecal Sludge Management written by Linda Strande and published by IWA Publishing. This book was released on 2014-08-15 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is estimated that literally billions of residents in urban and peri-urban areas of Africa, Asia, and Latin America are served by onsite sanitation systems (e.g. various types of latrines and septic tanks). Until recently, the management of faecal sludge from these onsite systems has been grossly neglected, partially as a result of them being considered temporary solutions until sewer-based systems could be implemented. However, the perception of onsite or decentralized sanitation technologies for urban areas is gradually changing, and is increasingly being considered as long-term, sustainable options in urban areas, especially in low- and middle-income countries that lack sewer infrastructures. This is the first book dedicated to faecal sludge management. It compiles the current state of knowledge of the rapidly evolving field of faecal sludge management, and presents an integrated approach that includes technology, management, and planning based on Sandecs 20 years of experience in the field. Faecal Sludge Management: Systems Approach for Implementation and Operation addresses the organization of the entire faecal sludge management service chain, from the collection and transport of sludge, and the current state of knowledge of treatment options, to the final end use or disposal of treated sludge. The book also presents important factors to consider when evaluating and upscaling new treatment technology options. The book is designed for undergraduate and graduate students, and engineers and practitioners in the field who have some basic knowledge of environmental and/or wastewater engineering.

What is the Code of Conduct for Responsible Fisheries?

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Publisher : Food & Agriculture Org.
ISBN 13 : 9789251045411
Total Pages : 20 pages
Book Rating : 4.0/5 (454 download)

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Book Synopsis What is the Code of Conduct for Responsible Fisheries? by : Food and Agriculture Organization of the United Nations

Download or read book What is the Code of Conduct for Responsible Fisheries? written by Food and Agriculture Organization of the United Nations and published by Food & Agriculture Org.. This book was released on 2001 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt: The actual Code of conduct is also available (1996) (ISBN 9251038341).

2nd Pan-African Symposium on the Sustainable Use of Natural Resources in Africa

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Publisher : IUCN
ISBN 13 : 2831706904
Total Pages : 344 pages
Book Rating : 4.8/5 (317 download)

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Book Synopsis 2nd Pan-African Symposium on the Sustainable Use of Natural Resources in Africa by : Bihini won wa Musiti

Download or read book 2nd Pan-African Symposium on the Sustainable Use of Natural Resources in Africa written by Bihini won wa Musiti and published by IUCN. This book was released on 2003 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: This bilingual publication results from a four-day symposium aimed at capturing the general directions and analytical issues that characterize approaches to sustainable use in Africa. The papers included in this work are organized under four major headings: modes of use, devolution, scale issues and external issues. Authors explore these themes through the use of case studies and the description of specific regional experiences. External issues are further explored in a series of commissioned policy papers which have also been included.

A German-English Dictionary for Chemists

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Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (33 download)

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Book Synopsis A German-English Dictionary for Chemists by : Austin McDowell Patterson

Download or read book A German-English Dictionary for Chemists written by Austin McDowell Patterson and published by . This book was released on 1935 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Aquaculture Development

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Publisher : Food & Agriculture Org.
ISBN 13 : 9789251039717
Total Pages : 52 pages
Book Rating : 4.0/5 (397 download)

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Book Synopsis Aquaculture Development by : Food and Agriculture Organization of the United Nations

Download or read book Aquaculture Development written by Food and Agriculture Organization of the United Nations and published by Food & Agriculture Org.. This book was released on 1997 with total page 52 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides annotations to the Principles of Article 9 of the Code of Conduct for Responsible Fisheries. These annotations are meant to serve as general guidance, and should be taken as suggestions or observations intended to assist those interested in identifying their own criteria and options for actions, as well as partners for collaboration, in support of sustainable aquaculture development.

Guide to the International Registration of Marks under the Madrid Agreement and the Madrid Protocol

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Publisher : WIPO
ISBN 13 : 9280530542
Total Pages : 191 pages
Book Rating : 4.2/5 (85 download)

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Book Synopsis Guide to the International Registration of Marks under the Madrid Agreement and the Madrid Protocol by : World Intellectual Property Organization

Download or read book Guide to the International Registration of Marks under the Madrid Agreement and the Madrid Protocol written by World Intellectual Property Organization and published by WIPO. This book was released on 2019-09-11 with total page 191 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Guide is primarily intended for applicants and holders of international registrations of marks, as well as officials of the competent administrations of the Member States of the Madrid Union. It leads them through the various steps of the international registration procedure and explains the essential provisions of the Madrid Agreement, the Madrid Protocol and the Common Regulations.

Exportateur Americain

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Publisher :
ISBN 13 :
Total Pages : 172 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Exportateur Americain by :

Download or read book Exportateur Americain written by and published by . This book was released on 1912 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Gautier de Coinci

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Publisher : Brepols Publishers
ISBN 13 :
Total Pages : 520 pages
Book Rating : 4.:/5 (321 download)

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Book Synopsis Gautier de Coinci by : Kathy M. Krause

Download or read book Gautier de Coinci written by Kathy M. Krause and published by Brepols Publishers. This book was released on 2006 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gautier de Coinci (c. 1177-1236) was a Benedictine prior, a poet and composer, and the author of several very popular religious works, including a large collection of Miracles of the Virgin in French, which enjoyed a wide circulation during the Middle Ages. Gautier drew on multiple Latin sources for his work, embellishing and personalizing them as he adapted them to his poetic design. Conceiving of his collection of miracles as a complete work, Gautier carefully organized the tales into two books, framing each with authorial exordia and lyrics praising the Virgin. In addition to its obvious literary interest, the subsequent manuscript tradition offers a remarkable panorama of medieval manuscript production, in particular due to the fascinating combination of text, music and illustration. Bringing together a select group of scholars from multiple disciplines (including art history, musicology, and literary studies), this collection of essays explores complementary aspects of Gautier, his works, and his manuscripts. The volume offers both breadth and depth in its examination of Gautier de Coinci and his Miracles de Nostre Dame It promises to redefine Gautier studies through its interdisciplinary consideration of the varied facets of his work as it makes available to scholars and students the first interdisciplinary examination of this key figure in medieval vernacular religious culture.

Protected Area Management

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Publisher : BoD – Books on Demand
ISBN 13 : 953510697X
Total Pages : 242 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Protected Area Management by : Barbara Sladonja

Download or read book Protected Area Management written by Barbara Sladonja and published by BoD – Books on Demand. This book was released on 2012-08-08 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: Protected areas are at the base of the most national and international conservation strategies. Due to the many unpredictable elements in ecology matters, each protected area requires a case-specific set of guidelines but a common issue is how to cope with human interaction. The management of protected areas is replete with challenges and the only way to gain understanding and achieve greater management possibilities is to exchange experiences and knowledge. Environmental managers are aware of that and together with scientists are looking for more modern and better solutions, both with respect to natural resources and human interactions in many issues regarding nature protection. This publication presents reviews and research results on protected areas management, as well as 12 case studies derived from around the world with the aim of improving management effectiveness of the protected areas.

Insects as Sustainable Food Ingredients

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Publisher : Academic Press
ISBN 13 : 0128028920
Total Pages : 404 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Insects as Sustainable Food Ingredients by : Aaron T. Dossey

Download or read book Insects as Sustainable Food Ingredients written by Aaron T. Dossey and published by Academic Press. This book was released on 2016-06-23 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: Insects as Sustainable Food Ingredients: Production, Processing and Food Applications describes how insects can be mass produced and incorporated into our food supply at an industrial and cost-effective scale, providing valuable guidance on how to build the insect-based agriculture and the food and biomaterial industry. Editor Aaron Dossey, a pioneer in the processing of insects for human consumption, brings together a team of international experts who effectively summarize the current state-of-the-art, providing helpful recommendations on which readers can build companies, products, and research programs. Researchers, entrepreneurs, farmers, policymakers, and anyone interested in insect mass production and the industrial use of insects will benefit from the content in this comprehensive reference. The book contains all the information a basic practitioner in the field needs, making this a useful resource for those writing a grant, a research or review article, a press article, or news clip, or for those deciding how to enter the world of insect based food ingredients. Details the current state and future direction of insects as a sustainable source of protein, food, feed, medicine, and other useful biomaterials Provides valuable guidance that is useful to anyone interested in utilizing insects as food ingredients Presents insects as an alternative protein/nutrient source that is ideal for food companies, nutritionists, entomologists, food entrepreneurs, and athletes, etc. Summarizes the current state-of-the-art, providing helpful recommendations on building companies, products, and research programs Ideal reference for researchers, entrepreneurs, farmers, policymakers, and anyone interested in insect mass production and the industrial use of insects Outlines the challenges and opportunities within this emerging industry