Alternative Splicing In The Postgenomic Era

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Alternative Splicing in the Postgenomic Era

Author : Benjamin J. Blencowe
Publisher : Springer Science & Business Media
ISBN 13 : 9780387773735
Total Pages : 260 pages
Book Rating : 4.7/5 (737 download)

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Book Synopsis Alternative Splicing in the Postgenomic Era by : Benjamin J. Blencowe

Download or read book Alternative Splicing in the Postgenomic Era written by Benjamin J. Blencowe and published by Springer Science & Business Media. This book was released on 2008-01-23 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: Yet again Springer has reached the market before everyone. This is the first book that is solely dedicated to the topic of alternative splicing. The book contains chapters by experts in the field that cover nearly all aspects of this hugely important subject. The purpose of the text is to provide a single, authoritative source of information on alternative splicing that is accessible to researchers in diverse fields. It is suitable for beginners and experts alike.

Surgical Thoracoscopy

Author : Rolf Inderbitzi
Publisher : Springer Verlag
ISBN 13 : 9780387568942
Total Pages : 159 pages
Book Rating : 4.5/5 (689 download)

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Book Synopsis Surgical Thoracoscopy by : Rolf Inderbitzi

Download or read book Surgical Thoracoscopy written by Rolf Inderbitzi and published by Springer Verlag. This book was released on 1994-01-01 with total page 159 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Alternative Splicing and Evolution in the Post-genomic Era

Author : Barmak Modrek
Publisher :
ISBN 13 :
Total Pages : 150 pages
Book Rating : 4.:/5 ( download)

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Book Synopsis Alternative Splicing and Evolution in the Post-genomic Era by : Barmak Modrek

Download or read book Alternative Splicing and Evolution in the Post-genomic Era written by Barmak Modrek and published by . This book was released on 2004 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Post-Transcriptional Gene Regulation

Author : Jane Wu
Publisher : John Wiley & Sons
ISBN 13 : 3527665412
Total Pages : 400 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Post-Transcriptional Gene Regulation by : Jane Wu

Download or read book Post-Transcriptional Gene Regulation written by Jane Wu and published by John Wiley & Sons. This book was released on 2013-04-24 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reflecting the rapid progress in the field, the book presents the current understanding of molecular mechanisms of post-transcriptional gene regulation thereby focusing on RNA processing mechanisms in eucaryotic cells. With chapters on mechanisms as RNA splicing, RNA interference, MicroRNAs, RNA editing and others, the book also discusses the critical role of RNA processing for the pathogenesis of a wide range of human diseases. The interdisciplinary importance of the topic makes the title a useful resource for a wide reader group in science, clinics as well as pharmaceutical industry.

RNA Splicing and Backsplicing: Disease and Therapy

Author : Rosanna Asselta
Publisher : Frontiers Media SA
ISBN 13 : 2889662357
Total Pages : 197 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis RNA Splicing and Backsplicing: Disease and Therapy by : Rosanna Asselta

Download or read book RNA Splicing and Backsplicing: Disease and Therapy written by Rosanna Asselta and published by Frontiers Media SA. This book was released on 2020-12-24 with total page 197 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Postgenomics

Author : Sarah S. Richardson
Publisher : Duke University Press
ISBN 13 : 0822375443
Total Pages : 286 pages
Book Rating : 4.8/5 (223 download)

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Book Synopsis Postgenomics by : Sarah S. Richardson

Download or read book Postgenomics written by Sarah S. Richardson and published by Duke University Press. This book was released on 2015-05-29 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ten years after the Human Genome Project’s completion the life sciences stand in a moment of uncertainty, transition, and contestation. The postgenomic era has seen rapid shifts in research methodology, funding, scientific labor, and disciplinary structures. Postgenomics is transforming our understanding of disease and health, our environment, and the categories of race, class, and gender. At the same time, the gene retains its centrality and power in biological and popular discourse. The contributors to Postgenomics analyze these ruptures and continuities and place them in historical, social, and political context. Postgenomics, they argue, forces a rethinking of the genome itself, and opens new territory for conversations between the social sciences, humanities, and life sciences. Contributors. Russ Altman, Rachel A. Ankeny, Catherine Bliss, John Dupré, Michael Fortun, Evelyn Fox Keller, Sabina Leonelli, Adrian Mackenzie, Margot Moinester, Aaron Panofsky, Sarah S. Richardson, Sara Shostak, Hallam Stevens

Biological and Medical Data Analysis

Author : Nicos Maglaveras
Publisher : Springer
ISBN 13 : 3540680659
Total Pages : 507 pages
Book Rating : 4.5/5 (46 download)

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Book Synopsis Biological and Medical Data Analysis by : Nicos Maglaveras

Download or read book Biological and Medical Data Analysis written by Nicos Maglaveras and published by Springer. This book was released on 2006-11-23 with total page 507 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the 7th International Symposium on Biological and Medical Data Analysis, ISBMDA 2006, held in Thessaloniki, Greece, December 2006. Coverage in this volume includes functional genomics, sequence analysis, biomedical models, information modeling, biomedical signal processing, biomedical image analysis, biomedical data analysis, as well as decision support systems and diagnostic tools.

Human T cell leukemia virus-1 (HTLV-1) infection, associated pathology and response of the host

Author : Roberto S. Accolla
Publisher : Frontiers Media SA
ISBN 13 : 2832527728
Total Pages : 248 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Human T cell leukemia virus-1 (HTLV-1) infection, associated pathology and response of the host by : Roberto S. Accolla

Download or read book Human T cell leukemia virus-1 (HTLV-1) infection, associated pathology and response of the host written by Roberto S. Accolla and published by Frontiers Media SA. This book was released on 2023-06-30 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Linkage in Evolutionary Computation

Author : Ying-ping Chen
Publisher : Springer Science & Business Media
ISBN 13 : 3540850678
Total Pages : 487 pages
Book Rating : 4.5/5 (48 download)

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Book Synopsis Linkage in Evolutionary Computation by : Ying-ping Chen

Download or read book Linkage in Evolutionary Computation written by Ying-ping Chen and published by Springer Science & Business Media. This book was released on 2008-09-26 with total page 487 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, the issue of linkage in GEAs has garnered greater attention and recognition from researchers. Conventional approaches that rely much on ad hoc tweaking of parameters to control the search by balancing the level of exploitation and exploration are grossly inadequate. As shown in the work reported here, such parameters tweaking based approaches have their limits; they can be easily ”fooled” by cases of triviality or peculiarity of the class of problems that the algorithms are designed to handle. Furthermore, these approaches are usually blind to the interactions between the decision variables, thereby disrupting the partial solutions that are being built up along the way.

Bioinformatics Research and Applications

Author : Ion Mandoiu
Publisher : Springer
ISBN 13 : 3642015514
Total Pages : 350 pages
Book Rating : 4.6/5 (42 download)

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Book Synopsis Bioinformatics Research and Applications by : Ion Mandoiu

Download or read book Bioinformatics Research and Applications written by Ion Mandoiu and published by Springer. This book was released on 2009-04-29 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the 5th International Symposium on Bioinformatics Research and Applications, ISBRA 2009, held in Fort Lauderdale, FL, USA, in May 2009. The 26 revised full papers presented together four invited papers were carefully reviewed and selected from a total of 55 submissions. The papers cover a wide range of topics, including clustering and classification, gene expression analysis, gene networks, genome analysis, motif finding, pathways, protein structure prediction, protein domain interactions, phylogenetics, and software tools.

Handbook of Neurotoxicity

Author : Richard M. Kostrzewa
Publisher : Springer Nature
ISBN 13 : 3031150805
Total Pages : 2551 pages
Book Rating : 4.0/5 (311 download)

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Book Synopsis Handbook of Neurotoxicity by : Richard M. Kostrzewa

Download or read book Handbook of Neurotoxicity written by Richard M. Kostrzewa and published by Springer Nature. This book was released on 2023-01-02 with total page 2551 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook is a reference source for identifying, characterizing, instructing on use, and describing outcomes of neurotoxin treatments – to understand mechanisms associated with toxin use; to project outcomes of neurotoxin treatments; to gauge neurotoxins as predictors of events leading to neurodegenerative disorders and as aids to rational use of neurotoxins to model disease entities. Neuroprotection is approached in different manners including those 1) afforded by therapeutic agents – clinical and preclinical; or 2) by non-drug means, such as exercise. The amorphous term ‘neurotoxin’ is discussed in terms of the possible eventuality of a neuroprotectant producing an outcome of excess neuronal survival and a behavioral spectrum that might produce a dysfunction – akin to a neurotoxin’s effect. This new edition significantly expands on the information provided in the first edition, providing the latest research in neurotoxicity and highlighting the relationship between specific neurotoxins and the neurodegenerative disorders they can cause. It also includes new sections on the neurotoxicity of heavy metals, fungi, and snake venom. The Handbook of Neurotoxicity is thus an instructive and valuable guide towards understanding the role of neurotoxins/neurotoxicity in the expansive field of Neuroscience, and is an indispensable tool for laboratory investigators, neuroscientists, and clinical researchers.

Biological Information

Author : Robert J Marks II
Publisher : World Scientific Publishing Company
ISBN 13 : 9814508721
Total Pages : 584 pages
Book Rating : 4.8/5 (145 download)

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Book Synopsis Biological Information by : Robert J Marks II

Download or read book Biological Information written by Robert J Marks II and published by World Scientific Publishing Company. This book was released on 2013-06-03 with total page 584 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the spring of 2011, a diverse group of scientists gathered at Cornell University to discuss their research into the nature and origin of biological information. This symposium brought together experts in information theory, computer science, numerical simulation, thermodynamics, evolutionary theory, whole organism biology, developmental biology, molecular biology, genetics, physics, biophysics, mathematics, and linguistics. This volume presents new research by those invited to speak at the conference. The contributors to this volume use their wide-ranging expertise in the area of biological information to bring fresh insights into the many explanatory difficulties associated with biological information. These authors raise major challenges to the conventional scientific wisdom, which attempts to explain all biological information exclusively in terms of the standard mutation/selection paradigm. Several clear themes emerged from these research papers: 1) Information is indispensable to our understanding of what life is; 2) Biological information is more than the material structures that embody it; 3) Conventional chemical and evolutionary mechanisms seem insufficient to fully explain the labyrinth of information that is life. By exploring new perspectives on biological information, this volume seeks to expand, encourage, and enrich research into the nature and origin of biological information.

Biological Information: New Perspectives - Proceedings Of The Symposium

Author : John C Sanford
Publisher : World Scientific
ISBN 13 : 981450873X
Total Pages : 584 pages
Book Rating : 4.8/5 (145 download)

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Book Synopsis Biological Information: New Perspectives - Proceedings Of The Symposium by : John C Sanford

Download or read book Biological Information: New Perspectives - Proceedings Of The Symposium written by John C Sanford and published by World Scientific. This book was released on 2013-06-03 with total page 584 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the spring of 2011, a diverse group of scientists gathered at Cornell University to discuss their research into the nature and origin of biological information. This symposium brought together experts in information theory, computer science, numerical simulation, thermodynamics, evolutionary theory, whole organism biology, developmental biology, molecular biology, genetics, physics, biophysics, mathematics, and linguistics. This volume presents new research by those invited to speak at the conference.The contributors to this volume use their wide-ranging expertise in the area of biological information to bring fresh insights into the many explanatory difficulties associated with biological information. These authors raise major challenges to the conventional scientific wisdom, which attempts to explain all biological information exclusively in terms of the standard mutation/selection paradigm.Several clear themes emerged from these research papers: 1) Information is indispensable to our understanding of what life is; 2) Biological information is more than the material structures that embody it; 3) Conventional chemical and evolutionary mechanisms seem insufficient to fully explain the labyrinth of information that is life. By exploring new perspectives on biological information, this volume seeks to expand, encourage, and enrich research into the nature and origin of biological information.

Binding Protein

Author : Kotb Abdelmohsen
Publisher : BoD – Books on Demand
ISBN 13 : 9535107585
Total Pages : 217 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Binding Protein by : Kotb Abdelmohsen

Download or read book Binding Protein written by Kotb Abdelmohsen and published by BoD – Books on Demand. This book was released on 2012-09-19 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proteins are essential for all cellular events. They bind or interact with additional players such as other proteins, peptides, DNA, and RNA to exert their functions. Revealing protein binding partners is important in understanding the mechanisms through which they function in the cells and the organism. These interactions are essential in the regulation of cell fates and could be important in drugs development. For example proteins can bind mRNA to regulate stability and translation. They also bind other proteins for degradation or proteolysis. These mRNAs and proteins could be involved in cellular processes such as cell survival or apoptosis. This book contains review articles dealing with protein interactions with the above mentioned factors. The enclosed articles could be informative and stimulating for readers interested in protein binding partners and the consequences of such interactions.

Progress in Nucleic Acid Research and Molecular Biology

Author : Kivie Moldave
Publisher : Elsevier
ISBN 13 : 9780125400787
Total Pages : 374 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Progress in Nucleic Acid Research and Molecular Biology by : Kivie Moldave

Download or read book Progress in Nucleic Acid Research and Molecular Biology written by Kivie Moldave and published by Elsevier. This book was released on 2004-08-02 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nucleic acids are the fundamental building blocks of DNA and RNA and are found in virtually every living cell. Molecular biology is a branch of science that studies the physicochemical properties of molecules in a cell, including nucleic acids, proteins, and enzymes. Increased understanding of nucleic acids and their role in molecular biology will further many of the biological sciences including genetics, biochemistry, and cell biology. Progress in Nucleic Acid Research and Molecular Biology is intended to bring to light the most recent advances in these overlapping disciplines with a timely compilation of reviews comprising each volume.

Gene Expression and Regulation in Mammalian Cells

Author : Fumiaki Uchiumi
Publisher : BoD – Books on Demand
ISBN 13 : 9535138553
Total Pages : 336 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Gene Expression and Regulation in Mammalian Cells by : Fumiaki Uchiumi

Download or read book Gene Expression and Regulation in Mammalian Cells written by Fumiaki Uchiumi and published by BoD – Books on Demand. This book was released on 2018-02-21 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Central dogma" was presented by Dr. Francis Crick 60 years ago. The information of nucleotide sequences on DNAs is transcribed into RNAs by RNA polymerases. We learned the mechanisms of how transcription determines function of proteins and behaviour of cells and even how it brings appearances of organisms. This book is intended for scientists and medical researchers especially who are interested in the relationships between transcription and human diseases. This volume consists of an introductory chapter and 14 chapters, divided into 4 parts. Each chapter is written by experts in the basic scientific field. A collection of articles presented by active and laboratory-based investigators provides recent advances and progresses in the field of transcriptional regulation in mammalian cells.

Metabolic Engineering in the Post Genomic Era

Author : Boris N. Kholodenko
Publisher : Garland Science
ISBN 13 : 9780954523220
Total Pages : 472 pages
Book Rating : 4.5/5 (232 download)

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Book Synopsis Metabolic Engineering in the Post Genomic Era by : Boris N. Kholodenko

Download or read book Metabolic Engineering in the Post Genomic Era written by Boris N. Kholodenko and published by Garland Science. This book was released on 2004 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Horizon Scientific Press titles focus on high-level microbiology and molecular biology topics. Written by internationally renowned and highly respected leaders in the field, titles in this series comprise of review manuals, practical manuals, and reference texts for research scientists, bioscience professionals and graduate students. Engineering living cells continues to pose immense challenges to the researcher. In fact many bioengineers have only just started to appreciate the full extent of the hierarchical control used by living systems: upon attempts to increase the activity of a "rate-limiting" step, the multiple feedbacks at the metabolic, signaling and genetic levels result in the rate limiting step shifting to elsewhere in that pathway or even to elsewhere in the whole organism. The advent of full-force genomics should enable preventing this response, however, it has been difficult for researchers to know where to turn for guidance. This book aims to help the reader understand and deal with the plasticity of living cell factories and to turn the plasticity into the desired rather than the adverse direction. The book brings together all the recent, most important breakthroughs in this exciting field: Internationally renowned key scientists have reviewed each topic in detail. In the Introduction, the editors give an overview of new approaches and spell out what the engineer and the industry may now really begin to aim for; they even adapt the definition of metabolic engineering to befit the post-genomics era. Other topics included are: the experimental approaches necessary to understand cellular regulation at all of its hierarchical levels, including proteomics [Chapter 2], metabolomics [Chapter 3] and fluxomics [Chapter 4]; new tools that help metabolic engineering [Chapters 5-7]; modeling of living cells, e.g. finding metabolic pathways [Chapter 8] and comparing the actual and predicted use of these in living organisms such as E. coli and Corynebacteria [Chapters 9, 10]; the optimization of cell factories as production organisms (e.g., use of whole cell models, silicon cells, and coordinate manipulation of multiple genes [Chapters 12-15]). A chapter on future perspectives directs further developments of the field in the near future. Metabolic Engineering in the Post Genomic Erais an essential reading for everyone with an interest in engineering living cells including: Metabolic egnineers, bioengineers, biotechnologists, molecular biologists, and pharmaceutical and biotechnology companies.