Advances in Time-of-flight Secondary Ion Mass Spectrometry for the Analysis of Single Cells on Sub-cellular Scale

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ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (711 download)

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Book Synopsis Advances in Time-of-flight Secondary Ion Mass Spectrometry for the Analysis of Single Cells on Sub-cellular Scale by : Sadia Rabbani

Download or read book Advances in Time-of-flight Secondary Ion Mass Spectrometry for the Analysis of Single Cells on Sub-cellular Scale written by Sadia Rabbani and published by . This book was released on 2010 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Advances in Time-of-flight Secondary Ion Mass Spectrometry for the Analysis of Single Cells on Sub-cellular Scale

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ISBN 13 :
Total Pages : 225 pages
Book Rating : 4.:/5 (711 download)

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Book Synopsis Advances in Time-of-flight Secondary Ion Mass Spectrometry for the Analysis of Single Cells on Sub-cellular Scale by : Sadia Rabbani

Download or read book Advances in Time-of-flight Secondary Ion Mass Spectrometry for the Analysis of Single Cells on Sub-cellular Scale written by Sadia Rabbani and published by . This book was released on 2010 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt:

An Introduction to Time-of-Flight Secondary Ion Mass Spectrometry (ToF-SIMS) and its Application to Materials Science

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Publisher : Morgan & Claypool Publishers
ISBN 13 : 1681740885
Total Pages : 67 pages
Book Rating : 4.6/5 (817 download)

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Book Synopsis An Introduction to Time-of-Flight Secondary Ion Mass Spectrometry (ToF-SIMS) and its Application to Materials Science by : Sarah Fearn

Download or read book An Introduction to Time-of-Flight Secondary Ion Mass Spectrometry (ToF-SIMS) and its Application to Materials Science written by Sarah Fearn and published by Morgan & Claypool Publishers. This book was released on 2015-10-16 with total page 67 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights the application of Time-of-Flight Secondary Ion Mass Spectrometry (ToF-SIMS) for high-resolution surface analysis and characterization of materials. While providing a brief overview of the principles of SIMS, it also provides examples of how dual-beam ToF-SIMS is used to investigate a range of materials systems and properties. Over the years, SIMS instrumentation has dramatically changed since the earliest secondary ion mass spectrometers were first developed. Instruments were once dedicated to either the depth profiling of materials using high-ion-beam currents to analyse near surface to bulk regions of materials (dynamic SIMS), or time-of-flight instruments that produced complex mass spectra of the very outer-most surface of samples, using very low-beam currents (static SIMS). Now, with the development of dual-beam instruments these two very distinct fields now overlap.

Secondary Ion Mass Spectrometry

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Publisher : Oxford University Press, USA
ISBN 13 :
Total Pages : 368 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Secondary Ion Mass Spectrometry by : J. C. Vickerman

Download or read book Secondary Ion Mass Spectrometry written by J. C. Vickerman and published by Oxford University Press, USA. This book was released on 1989 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an overview of the phenomenology, technology and application of secondary ion mass spectrometry as a technique for materials analysis. This approach is developing into one of the most effective methods of characterizing the composition and chemical state of the surface and sub-surface layers of solid materials. The first three chapters introduce the basic physical and chemical principles involved and the theories which have been proposed to explain the process. Subsequent chapters describe the instrumental components of the SIMS apparatus, the use of SIMS as an analytical tool, and the development of the techniques of sputtered neutral mass spectrometry and laser microprobe and plasma desorption mass spectrometry. Many practical examples are featured to illustrate the application of SIMS to real problems, possible pitfalls are pointed out, and data of use to analysts are collected in appendices. The book is a practical guide suitable for scientists in all fields who wish to use this valuable analytical technique.

The Practice of TOF-SIMS

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Publisher : Momentum Press
ISBN 13 : 1606507745
Total Pages : 267 pages
Book Rating : 4.6/5 (65 download)

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Book Synopsis The Practice of TOF-SIMS by : Alan M. Spool

Download or read book The Practice of TOF-SIMS written by Alan M. Spool and published by Momentum Press. This book was released on 2016-03-24 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: Time of flight secondary ion mass spectrometry, TOF-SIMS, is a highly surface sensitive analytical technique that provides information about composition with submicron lateral resolution. For select materials, TOF-SIMS provides unparalleled sensitivity along with excellent reproducibility, and as a mass spectrometric technique, it also provides excellent specificity. Of the analytical methods available, it is among the most surface sensitive, but the physical principles that underlie it are also the least understood. This volume describes the instrumentation, the physical principles behind the technique to the extent they are understood, and provides a practical approach for the interpretation of TOF-SIMS data. The use of advanced data processing methods such as multivariate statistics are described in a readily approachable manner. Given a basic background in undergraduate chemistry and physics, the book will be of use to any student with an interest in the technique.

Visualisation and Profiling of Lipids in Single Biological Cells Using Time-of-Flight Secondary Ion Mass Spectrometry

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Publisher :
ISBN 13 :
Total Pages : 155 pages
Book Rating : 4.:/5 (827 download)

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Book Synopsis Visualisation and Profiling of Lipids in Single Biological Cells Using Time-of-Flight Secondary Ion Mass Spectrometry by : Hua Tian

Download or read book Visualisation and Profiling of Lipids in Single Biological Cells Using Time-of-Flight Secondary Ion Mass Spectrometry written by Hua Tian and published by . This book was released on 2011 with total page 155 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Secondary Ion Mass Spectrometry

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Publisher : Momentum Press
ISBN 13 : 1606505890
Total Pages : 233 pages
Book Rating : 4.6/5 (65 download)

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Book Synopsis Secondary Ion Mass Spectrometry by : Fred Stevie

Download or read book Secondary Ion Mass Spectrometry written by Fred Stevie and published by Momentum Press. This book was released on 2015-09-15 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book was written to explain a technique that requires an understanding of many details in order to properly obtain and interpret the data obtained. It also will serve as a reference for those who need to provide SIMS data. The book has over 200 figures and the references allow one to trace development of SIMS and understand the many details of the technique.

The Practice of TOF-SIMS

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Publisher :
ISBN 13 : 9781606507735
Total Pages : 0 pages
Book Rating : 4.5/5 (77 download)

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Book Synopsis The Practice of TOF-SIMS by : Alan M. Spool

Download or read book The Practice of TOF-SIMS written by Alan M. Spool and published by . This book was released on 2016 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Time of flight secondary ion mass spectrometry, TOF-SIMS, is a highly surface sensitive analytical technique that can provide information about composition with submicron lateral resolution for a wide variety of materials. In conjunction with the latest cluster ion sources, organic depth profiling is also commonly performed now. For select materials, TOF-SIMS provides unparalleled sensitivity along with excellent reproducibility, and as a mass spectrometric technique, it also provides excellent specificity in the identification of many organic materials. Of the analytical methods available, it is among the most surface sensitive, but the physical principles that underlie it are also the least understood. This volume describes the instrumentation, the physical principles behind the technique to the extent they are understood, and provides a practical approach for the interpretation of TOF-SIMS data. The use of advanced data processing methods such as multivariate statistics are described in a readily approachable manner along with guidelines to help the reader understand where they are or are not really helpful. Given a basic background in undergraduate chemistry and physics, the book will be of use to any student with an interest in the technique. While the analyses are in fact performed in a vacuum, they are conducted in the context of a wider laboratory environment where many other analytical methods are available. The place of TOF-SIMS amongst them, when it is appropriate to use this method or another, or when multiple methods should be used in conjunction with TOF-SIMS is discussed in some depth. Examples of the wide range of applications of TOF-SIMS for research and problem solving in Academic Laboratories, National Laboratories, and Industrial laboratories, as it is applied to polymeric, biological, semiconductor, metallic, insulating, homogeneous, and inhomogeneous surfaces are described.

Secondary Ion Mass Spectrometry

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Publisher : John Wiley & Sons
ISBN 13 : 1118916778
Total Pages : 412 pages
Book Rating : 4.1/5 (189 download)

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Book Synopsis Secondary Ion Mass Spectrometry by : Paul van der Heide

Download or read book Secondary Ion Mass Spectrometry written by Paul van der Heide and published by John Wiley & Sons. This book was released on 2014-08-19 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: Serves as a practical reference for those involved in Secondary Ion Mass Spectrometry (SIMS) • Introduces SIMS along with the highly diverse fields (Chemistry, Physics, Geology and Biology) to it is applied using up to date illustrations • Introduces the accepted fundamentals and pertinent models associated with elemental and molecular sputtering and ion emission • Covers the theory and modes of operation of the instrumentation used in the various forms of SIMS (Static vs Dynamic vs Cluster ion SIMS) • Details how data collection/processing can be carried out, with an emphasis placed on how to recognize and avoid commonly occurring analysis induced distortions • Presented as concisely as believed possible with All sections prepared such that they can be read independently of each other

Secondary Ion Mass Spectrometry

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Publisher : Wiley-Interscience
ISBN 13 :
Total Pages : 392 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Secondary Ion Mass Spectrometry by : Robert G. Wilson

Download or read book Secondary Ion Mass Spectrometry written by Robert G. Wilson and published by Wiley-Interscience. This book was released on 1989-11-16 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Seco ndary Ion Mass Spectrometry Basic Concepts, Instrumental Aspects, Applications and Trends (Volume 86 in Chemical Analysis: A Series of Monographs on Analytical Chemistry and Its Applications) A. Benninghoven, F. G. Rüdenauer, and H. W. Werner "[This book] is (and probably will be for a long time ahead) the standard book on secondary ion mass spectrometry." —Trends in Analytical Chemistry "This is a monumental work, and contains nearly 600 illustrations and over 2,000 references covering nearly all the essential published information up to 1985. The book will certainly find its place as a reference work in most laboratories using this methodology" —Analytica Chimica Acta 1987 (0 471-01056-1) 1,227 pp. Secondary Ion Mass Spectrometry Proceedings of the Sixth International Conference on Secondary Ion Mass Spectrometry (SIMS VI) Edited by A. Benninghoven, A.M. Huber, and H. W. Werner "The international SIMS conferences have been held every two years since 1977. They are recognized as one of the major forums for scientists, instrument manufacturers, and other researchers actively engaged in this rapidly expanding field…this volume is a valuable account of the latest advances in the field of SIMS, and of the research trends of some of the most respected experts in the field.…it is recommended for the libraries of all academic and industrial institutions where SIMS research is ongoing.…it should prove a valuable reference source for years to come." —Applied Spectroscopy 1988 (0 471-91832-6) 1,078 pp.

Secondary Ion Mass Spectrometry

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Publisher : Elsevier Science & Technology
ISBN 13 :
Total Pages : 1092 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Secondary Ion Mass Spectrometry by : A. Benninghoven

Download or read book Secondary Ion Mass Spectrometry written by A. Benninghoven and published by Elsevier Science & Technology. This book was released on 2000 with total page 1092 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hardbound. This biennial conference series is the first international forum covering developments in Secondary Ion Mass Spectrometry. All aspects of the most recent developments in SIMS were covered by the scientific program: fundamentals, instrumentation, methodology, and analytical applications in different fields (semiconductors, polymer and organic materials, life sciences, environmental sciences, earth sciences, materials science). Related techniques and topics were also included.

Application of Time-of-flight Secondary Ion Mass Spectrometry to Cellular Analysis

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Publisher :
ISBN 13 :
Total Pages : 220 pages
Book Rating : 4.:/5 (643 download)

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Book Synopsis Application of Time-of-flight Secondary Ion Mass Spectrometry to Cellular Analysis by : Matthew J. Baker

Download or read book Application of Time-of-flight Secondary Ion Mass Spectrometry to Cellular Analysis written by Matthew J. Baker and published by . This book was released on 2007 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Accounting for the Dead Time in Analysis of Time of Flight Secondary Ion Mass Spectrometry Data

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (19 download)

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Book Synopsis Accounting for the Dead Time in Analysis of Time of Flight Secondary Ion Mass Spectrometry Data by : Negar Shahrokhesfahani

Download or read book Accounting for the Dead Time in Analysis of Time of Flight Secondary Ion Mass Spectrometry Data written by Negar Shahrokhesfahani and published by . This book was released on 2018 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Time of Flight Secondary Ion Mass Spectrometry (ToF SIMS) is a powerful tool for advanced surface analysis. It produces large data sets, which consist of mass spectra at each pixel at an imaged area. Many ToF SIMS instruments use a type of detector that suffers from two problems that lead to non-linearity in the measured sample properties: detector saturation and dead time. Linearity in this type of system is defined as the proportionality of the measured and true ion counts. Non-linearity can influence the interpretation of the data with methods such as multivariate analysis. "Detector saturation" happens when more than one ion arrives at the detector in the time interval related to one specific channel but the detector records only a single count. "Dead time" is when one event happens at a certain channel and the detector become insensitive to subsequent ions arriving within the dead time window. These problems both lead to under-counting of ions. In this thesis, we mainly focus on correcting for the dead time effects. Using extensive simulations, we first characterize the adverse effects of dead time on the output and evaluate quality of existing ways to "correct" for dead time effects. Then, we propose a novel method using the Maximum Likelihood Estimation (MLE) to estimate the true spectrum for the measured data. Specifically, we incorporate the statistical distribution of the dead time affected data in MLE, which leads to a new method for dead time correction.

Advances in Time-of-flight Mass Spectrometry for Atomic and Molecular Analysis

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Publisher :
ISBN 13 :
Total Pages : 670 pages
Book Rating : 4.3/5 ( download)

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Book Synopsis Advances in Time-of-flight Mass Spectrometry for Atomic and Molecular Analysis by : John P. Guzowski

Download or read book Advances in Time-of-flight Mass Spectrometry for Atomic and Molecular Analysis written by John P. Guzowski and published by . This book was released on 2000 with total page 670 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Tracked Changes. Surface Chemical Analysis. Secondary Ion Mass Spectrometry. Linearity of Intensity Scale in Single Ion Counting Time-of-flight Mass Analysers

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ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (14 download)

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Book Synopsis Tracked Changes. Surface Chemical Analysis. Secondary Ion Mass Spectrometry. Linearity of Intensity Scale in Single Ion Counting Time-of-flight Mass Analysers by : British Standards Institution

Download or read book Tracked Changes. Surface Chemical Analysis. Secondary Ion Mass Spectrometry. Linearity of Intensity Scale in Single Ion Counting Time-of-flight Mass Analysers written by British Standards Institution and published by . This book was released on 2023 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Surface Chemical Analysis. Secondary Ion Mass Spectrometry. Linearity of Intensity Scale in Single Ion Counting Time-of-Flight Mass Analysers

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Publisher :
ISBN 13 : 9780580786846
Total Pages : 36 pages
Book Rating : 4.7/5 (868 download)

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Book Synopsis Surface Chemical Analysis. Secondary Ion Mass Spectrometry. Linearity of Intensity Scale in Single Ion Counting Time-of-Flight Mass Analysers by : British Standards Institute Staff

Download or read book Surface Chemical Analysis. Secondary Ion Mass Spectrometry. Linearity of Intensity Scale in Single Ion Counting Time-of-Flight Mass Analysers written by British Standards Institute Staff and published by . This book was released on 1913-12-31 with total page 36 pages. Available in PDF, EPUB and Kindle. Book excerpt: Surface chemistry, Chemical analysis and testing, Surfaces, Mass spectrometry, Mass spectrometers, Secondary, Ions, Calibration, Control samples

Secondary Ion Mass Spectrometry SIMS V

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Publisher : Springer Science & Business Media
ISBN 13 : 3642827241
Total Pages : 578 pages
Book Rating : 4.6/5 (428 download)

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Book Synopsis Secondary Ion Mass Spectrometry SIMS V by : Alfred Benninghoven

Download or read book Secondary Ion Mass Spectrometry SIMS V written by Alfred Benninghoven and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 578 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains the proceedings of the Fifth International Confer ence on Secondary Ion Mass Spectrometry (SIMS V), held at the Capitol Holiday Inn, Washington, DC, USA, from September 30 to October 4, 1985. The conference was the fifth in a series of conferences held bienni ally. Previous conferences were held in Miinster (1977), Stanford (1979), Budapest (1981), and Osaka (1983). SIMS V was organized by Dr. R.J. Colton of the Nayal Research Lab oratory and Dr. D.S. Simons of the National Bureau of Standards un der the auspices of the International Organizing Committee chaired by Prof. A. Benninghoven of the Universitat Miinster. Dr. Richard F.K. Herzog served as the honorary chairman of SIMS V. While Dr. Herzog is best known to the mass spectrometry community for his theoretical development of a mass spectrometer design, known as the Mattauch-Herzog geometry, he also made several early and impor tant contributions to SIMS. In 1949, Herzog and Viehbock published a description of the first instrument designed to study secondary ions pro duced by bombardment from a beam of ions generated in a source that was separated from the sample by a narrow tube. Later at the GCA Cor poration, he brought together a team of researchers including H.J. Liebl, F.G. Riidenauer, W.P. Poschenrieder and F.G. Satkiewicz, who designed and built, and carried out applied research with the first commercial ion microprobe.