Advances In Molecular Genetics Of Brain Tumors

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Advances in Molecular Genetics of Brain Tumors

Author : Nives Pecina-Slaus
Publisher : Mdpi AG
ISBN 13 : 9783036566443
Total Pages : 0 pages
Book Rating : 4.5/5 (664 download)

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Book Synopsis Advances in Molecular Genetics of Brain Tumors by : Nives Pecina-Slaus

Download or read book Advances in Molecular Genetics of Brain Tumors written by Nives Pecina-Slaus and published by Mdpi AG. This book was released on 2023-02-23 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book encompasses a number of articles that focus on the molecular blueprint of brain tumors. A collection of relevant papers in the rapidly expanding field of brain tumor molecular genetics broadens our knowledge about the biology of brain tumors, and inspires further studies that will improve the diagnosis and clinical management of brain tumors. Due to the great heterogeneity of brain tumors it is important to research and understand every aspect of their initiation, progression and metastasis in order to design better diagnostic and therapeutic approaches for their clinical management and patient benefit.

Brain Tumor Invasion

Author : Tom Mikkelsen
Publisher : Wiley-Liss
ISBN 13 :
Total Pages : 494 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Brain Tumor Invasion by : Tom Mikkelsen

Download or read book Brain Tumor Invasion written by Tom Mikkelsen and published by Wiley-Liss. This book was released on 1998-05-05 with total page 494 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain Tumor Invasion Biological, Clinical, and Therapeutic Considerations Edited by Tom Mikkelsen Rolf Bjerkvig Ole Didrik Laerum Mark L. Rosenblum Recent advances in molecular biology have given us profound new insights into the behavior of primary brain tumors. Not only are such tumors more diffuse in their infiltration of brain tissue and therefore less amenable to surgery than brain tumors originating elsewhere in the body—it now appears that the central nervous system and the normal brain itself constitute a biological environment conducive to the uncontrolled spread of primary tumors. Brain Tumor Invasion is the first comprehensive reference devoted to the invasive behavior of primary brain tumors. It examines the biological mechanisms responsible for the increased ability of gliomas to metastasize in the central nervous system, and discusses the role of chemical carcinogens, growth factors, oncogenes, and tumor suppressors in the progression of such metastases. This book surveys the latest research in the field, reviews present and future prospects of anti-invasive brain tumor therapy, and even translates preclinical trials and other research results into potential new therapies. The material is divided into five main categories: Developmental biology and molecular neuro-oncology Pathological and clinical features of malignant brain tumors Models for the study of brain tumor invasion in vivo and in vitro Mechanisms of invasion New therapeutic strategies Brain Tumor Invasion offers dozens of maps and photographs that illustrate topics under discussion. This in-depth introduction to one of the most difficult problems in the management of brain tumors is indispensable to neuro-oncologists involved in brain tumor research and therapy. It is also useful to researchers in cancer biology, neuroscience, cell biology, and molecular genetics.

Evolution of the Molecular Biology of Brain Tumors and the Therapeutic Implications

Author : Terry Lichtor
Publisher : BoD – Books on Demand
ISBN 13 : 9535109898
Total Pages : 652 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Evolution of the Molecular Biology of Brain Tumors and the Therapeutic Implications by : Terry Lichtor

Download or read book Evolution of the Molecular Biology of Brain Tumors and the Therapeutic Implications written by Terry Lichtor and published by BoD – Books on Demand. This book was released on 2013-02-27 with total page 652 pages. Available in PDF, EPUB and Kindle. Book excerpt: A dramatic increase in knowledge regarding the molecular biology of brain tumors has been established over the past few years. In particular recent new avenues regarding the role of stem cells and microRNAs along with further understanding of the importance of angiogenesis, immunotherapy and explanations for the resistance of the tumors to chemotherapeutic agents and radiation therapy has been developed. It is hopeful that this new information will lead to efficacious treatment strategies for these tumors which remain a challenge. In this book a review of the latest information on these topics along with a variety of new therapeutic treatment strategies with an emphasis on molecular targeted therapies is provided.

Molecular Advances in Diagnosis and Treatment of CNS Tumors

Author : Liam Chen
Publisher : Frontiers Media SA
ISBN 13 : 2889661644
Total Pages : 283 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Molecular Advances in Diagnosis and Treatment of CNS Tumors by : Liam Chen

Download or read book Molecular Advances in Diagnosis and Treatment of CNS Tumors written by Liam Chen and published by Frontiers Media SA. This book was released on 2020-12-09 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Clinical Management and Evolving Novel Therapeutic Strategies for Patients with Brain Tumors

Author : Terry Lichtor
Publisher : BoD – Books on Demand
ISBN 13 : 9535110586
Total Pages : 656 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Clinical Management and Evolving Novel Therapeutic Strategies for Patients with Brain Tumors by : Terry Lichtor

Download or read book Clinical Management and Evolving Novel Therapeutic Strategies for Patients with Brain Tumors written by Terry Lichtor and published by BoD – Books on Demand. This book was released on 2013-04-10 with total page 656 pages. Available in PDF, EPUB and Kindle. Book excerpt: A dramatic increase in knowledge regarding the molecular biology of brain tumors has been established over the past few years, and this has lead to the development of novel therapeutic strategies for these patients. In this book a review of the options available for the clinical management of patients with these tumors are outlined. In addition advances in radiology both for pre-operative diagnostic purposes along with surgical planning are described. Furthermore a review of newer developments in chemotherapy along with the evolving field of photodynamic therapy both for intra-operative management and subsequent therapy is provided. A discussion of certain surgical management issues along with tumor induced epilepsy is included. Finally a discussion of the management of certain unique problems including brain metastases, brainstem glioma, central nervous system lymphoma along with issues involving patients with a brain tumor and pregnancy is provided.

Brain Tumors

Author : Francis Ali-Osman
Publisher : Springer Science & Business Media
ISBN 13 : 1592598439
Total Pages : 392 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Brain Tumors by : Francis Ali-Osman

Download or read book Brain Tumors written by Francis Ali-Osman and published by Springer Science & Business Media. This book was released on 2007-10-28 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Exciting new developments and discoveries of the last two decades are beginning to shed light on the complex biology of brain tumors and are advancing our understa- ing of the cellular and molecular processes involved in their initiation, progression, and clinical and biological behavior. The disease process in brain tumors is quite complex and the resulting tumors are characterized by a high degree of biological and clinical diversity. Thus, despite the advances of the last two decades, prognosis for patients with malignant brain tumors remains abysmal. Significant progress in the diagnosis, treatment and, ultimately, prevention of these tumors will require both the timely h- nessing of the advances in basic and clinical brain tumor research, and a continuing concerted effort at increasing our understanding of brain tumor biology, in particular, the molecular genetic changes and perturbations of cellular pathways involved in brain oncogenesis and which drive the biological and clinical behavior of the tumors. Brain tumor diagnosis and prognosis, which is still largely based on histopathology and other clinical criteria, will, in the future, acquire a significant molecular component, with the incorporation of knowledge of genes that are mutated, over-expressed, deleted, silenced, or functionally altered in the tumors. Treatment strategies for brain tumors, rather than being empirical, will be rationally developed based on an understanding of the cellular and molecular mechanisms and targets that have been activated, suppressed, or otherwise altered.

Central Nervous System Tumours

Author : Thomas James Deeley
Publisher :
ISBN 13 :
Total Pages : 346 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Central Nervous System Tumours by : Thomas James Deeley

Download or read book Central Nervous System Tumours written by Thomas James Deeley and published by . This book was released on 1974 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Manuale dell'esercitatore

Author :
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (633 download)

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Book Synopsis Manuale dell'esercitatore by :

Download or read book Manuale dell'esercitatore written by and published by . This book was released on 1840 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Heterogeneity of Cancer Metabolism

Author : Anne Le
Publisher : Springer
ISBN 13 : 331977736X
Total Pages : 186 pages
Book Rating : 4.3/5 (197 download)

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Book Synopsis The Heterogeneity of Cancer Metabolism by : Anne Le

Download or read book The Heterogeneity of Cancer Metabolism written by Anne Le and published by Springer. This book was released on 2018-06-26 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, we delve into the complexity and diversity of cancer metabolism, and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer therapeutic strategies.

Report of the Brain Tumor Progress Review Group

Author : Brain Tumor Progress Review Group
Publisher :
ISBN 13 :
Total Pages : 114 pages
Book Rating : 4.:/5 (327 download)

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Book Synopsis Report of the Brain Tumor Progress Review Group by : Brain Tumor Progress Review Group

Download or read book Report of the Brain Tumor Progress Review Group written by Brain Tumor Progress Review Group and published by . This book was released on 2000 with total page 114 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Molecular Neuro-oncology and Its Impact on the Clinical Management of Brain Tumors

Author : O.D. Wiestler
Publisher : Springer Science & Business Media
ISBN 13 : 3642850391
Total Pages : 311 pages
Book Rating : 4.6/5 (428 download)

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Book Synopsis Molecular Neuro-oncology and Its Impact on the Clinical Management of Brain Tumors by : O.D. Wiestler

Download or read book Molecular Neuro-oncology and Its Impact on the Clinical Management of Brain Tumors written by O.D. Wiestler and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tumors of the nervous system represent a difficult therapeutic challenge. During recent years, substantial progress has been made in characterizing genetic mechnisms involved in the formation of brain tumors. There is a lot of hope that an understanding of the molecular basis of transformation will eventually lead to specific therapeutic approaches. In this volume, leading authorities in both molecular and clinical neuro-oncology summarize recent developments in their respective fields. The first part of the book will focus on specific molecular genetic defects in neural tumors and their potential clinical significance. Part two gives an update on established and novel treatment regimens for patients with brain tumors. Several contributions will demonstrate that molecular and clinical neuro-oncology are already entangled. With its unique combination of molecular biological and clinical data, this volume provides basic researchers and clinical neuroscientists with a comprehensive update in both disciplines.

Neurooncology

Author : Amit Agrawal
Publisher : BoD – Books on Demand
ISBN 13 : 9535124250
Total Pages : 490 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Neurooncology by : Amit Agrawal

Download or read book Neurooncology written by Amit Agrawal and published by BoD – Books on Demand. This book was released on 2016-07-13 with total page 490 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book contains the information of various aspects of newer developments and recent advances in the field of central nervous system (CNS) tumor molecular biology, tumor progression, clinical presentation, imaging and management. The authors from different reputed institutions shared their knowledge on this open access platform to disseminate their knowledge at global level. As it is obvious in the current text, the field of neurooncology is heterogeneous and under continuous development with addition of new knowledge and information on regular basis. The collective contributions from experts attempt to provide updates regarding ongoing research and developments pertaining to CNS tumor genetics and molecular aspects and their applied aspect in reference to patient management.

The Genetics and Molecular Biology of Neural Tumors

Author : Avery A. Sandberg
Publisher : Springer Science & Business Media
ISBN 13 : 1597455105
Total Pages : 453 pages
Book Rating : 4.5/5 (974 download)

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Book Synopsis The Genetics and Molecular Biology of Neural Tumors by : Avery A. Sandberg

Download or read book The Genetics and Molecular Biology of Neural Tumors written by Avery A. Sandberg and published by Springer Science & Business Media. This book was released on 2008-05-06 with total page 453 pages. Available in PDF, EPUB and Kindle. Book excerpt: Collecting an extensive amount of information from thousands of publications by leading investigators in this rapidly developing field, this book provides a convenient and up-to-date one volume source for research in neural tumors of various cellular origins. With over 3,500 references, 110 figures and 120 tables, this volume gathers an astonishing body of knowledge regarding human neural tumors. This book is the first of its kind, encyclopedic and wide-ranging.

Molecular Considerations and Evolving Surgical Management Issues in the Treatment of Patients with a Brain Tumor

Author : Terry Lichtor
Publisher : BoD – Books on Demand
ISBN 13 : 953512031X
Total Pages : 436 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Molecular Considerations and Evolving Surgical Management Issues in the Treatment of Patients with a Brain Tumor by : Terry Lichtor

Download or read book Molecular Considerations and Evolving Surgical Management Issues in the Treatment of Patients with a Brain Tumor written by Terry Lichtor and published by BoD – Books on Demand. This book was released on 2015-03-25 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: A dramatic increase in knowledge regarding the molecular biology of brain tumors has been established over the past few years. In particular, recent new avenues regarding the role of microRNAs along with further understanding of the importance of angiogenesis, immunotherapy and explanations for the resistance of the tumors to radiation therapy have been developed. A discussion of certain surgical management issues including improvements in imaging along with issues concerning tumor induced epilepsy is included. It is hopeful that this new information will lead to efficacious treatment strategies for these tumors which remain a challenge. In this book, a review of the latest information on these topics along with a variety of new therapeutic treatment strategies with an emphasis on molecular targeted therapies is provided.

Molecular Genetics of Brain Tumors

Author : Michelle Alonso
Publisher :
ISBN 13 :
Total Pages : 370 pages
Book Rating : 4.:/5 (587 download)

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Book Synopsis Molecular Genetics of Brain Tumors by : Michelle Alonso

Download or read book Molecular Genetics of Brain Tumors written by Michelle Alonso and published by . This book was released on 2001 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Molecular Genetics of Nervous System Tumors

Author : Arnold J. Levine
Publisher : Wiley-Liss
ISBN 13 :
Total Pages : 454 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Molecular Genetics of Nervous System Tumors by : Arnold J. Levine

Download or read book Molecular Genetics of Nervous System Tumors written by Arnold J. Levine and published by Wiley-Liss. This book was released on 1993-05-14 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: A host of renowned multinational scientists and clinicians present the latest advances that will impact diagnosis, pathological classification and treatment of nervous system tumors. These findings allow for anatomic delineation and subsequent removal of tumors for almost anywhere within the human nervous sytem at an acceptable risk level. Includes recent results on studies of cell proliferation regulation.

Handbook of Brain Tumor Chemotherapy

Author : Herbert B. Newton
Publisher : Elsevier
ISBN 13 : 008045593X
Total Pages : 554 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Handbook of Brain Tumor Chemotherapy by : Herbert B. Newton

Download or read book Handbook of Brain Tumor Chemotherapy written by Herbert B. Newton and published by Elsevier. This book was released on 2005-12-19 with total page 554 pages. Available in PDF, EPUB and Kindle. Book excerpt: Treatment of patients with a brain tumor remains one of the most challenging and difficult areas of modern oncology. Recent advances in the molecular biology of these neoplasms have improved our understanding of the malignant phenotype and have lead to the development of novel forms of chemotherapy, including “targeted agents. The Handbook of Brain Tumor Chemotherapy reviews the state-of-the-art of chemotherapy development and clinical treatment of patients with this devastating disease. Handbook of Brain Tumor Chemotherapy offers a unique cutting-edge compendium of basic science and clinical information on the subject of brain tumor chemotherapy, reviewing what has been accomplished thus far and how the field will continue to evolve with the development of more specific and efficacious chemotherapeutic agents. This book represents the most complete single-volume resource available for information on the subject of brain tumor chemotherapy. Provides the most up to date information regarding conventional forms of cytotoxic chemotherapy, as well as the basic science and clinical application of molecular therapeutics, for the treatment of brain tumors Broadly appeals to anyone interested in the field of Neuro-Oncology and in the treatment of patients with brain tumors Useful to clinicians interested in a thorough overview of the use of chemotherapy in patients with a broad range of brain tumors as well as serving as a source of background information to basic scientists and pharmaceutical researchers with an interest in the molecular therapeutics of brain tumors