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Advances In Esophageal Cancer Surgery With Neoadjuvant Therapies
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Download or read book The Esophagus written by Joel E. Richter and published by John Wiley & Sons. This book was released on 2021-07-13 with total page 73 pages. Available in PDF, EPUB and Kindle. Book excerpt: THE ESOPHAGUS The Esophagus investigates the anatomy, physiology, and pathology of the esophagus. This sixth edition, revised and updated throughout, also explores the diagnosis and treatment of various esophageal conditions. It includes treatment guidelines approved by the two largest gastroenterology societies, the ACG and AGA, as befits a work co-edited by two former presidents of those organizations. Advancements in diagnostics are presented, as are developments in the surgical and drug therapies. Presented in full colour, and boasting an unrivalled team of editors and contributing authors, The Esophagus Sixth Edition will find a home wherever the anatomy, physiology, and pathology of the esophagus are studied and taught. This book is accompanied by a website containing all the figures from the book in PowerPoint format. www.wiley.com/go/richter/esophagus6e Praise for the Fifth Edition: “There is absolutely no doubt that this edition of the textbook will maintain its status as the go-to reference for esophageal conditions, and will remain a highly utilized and clinically useful resource for novice and experienced physicians and surgeons alike.” (Gastroenterology, 1 July 2013)
Book Synopsis Advances in Esophageal Cancer Surgery with Neoadjuvant Therapies by : Mingqiang Kang
Download or read book Advances in Esophageal Cancer Surgery with Neoadjuvant Therapies written by Mingqiang Kang and published by Frontiers Media SA. This book was released on 2023-12-01 with total page 137 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Esophageal Squamous Cell Carcinoma by : Nobutoshi Ando
Download or read book Esophageal Squamous Cell Carcinoma written by Nobutoshi Ando and published by Springer. This book was released on 2014-10-22 with total page 313 pages. Available in PDF, EPUB and Kindle. Book excerpt: Esophageal cancer causes an estimated 386,000 deaths worldwide and is the sixth most common cause of death for men. The background characteristics of esophageal cancer treatment are markedly different between Asian and Western countries, however. In tumor histology, squamous cell carcinoma associated with smoking and alcohol consumption is overwhelmingly prevalent in Asia, whereas adenocarcinoma associated with Barrett’s metaplasia is markedly prevalent in the West. In Asia, especially in Japan, the key persons who play important roles in the management of esophageal cancer patients are surgeons; in the West those roles are filled by medical and radiation oncologists as well as surgeons. The philosophy of surgeons regarding cancer surgery varies from locoregional to local tumor control, particularly in focusing on lymph node dissection. Physicians’ approach to surgical adjuvant therapy differs, therefore, between Asia and the West. Considering these East–West differences in esophageal cancer treatment, the currently available results of Western evidence should not be considered directly applicable to esophageal cancer in Asia. In this book, the authors discuss the knowledge base in Japan in terms of treatment of esophageal squamous cell carcinoma. Since this volume contains a wide spectrum of current information and addresses topics surrounding the treatment of patients with esophageal squamous cell carcinoma, it is highly relevant to Asian physicians and researchers as well as to their counterparts in the West.
Book Synopsis ESOPEC: Prospective Randomized Controlled Multicenter Phase III Trial Comparing Perioperative Chemotherapy (FLOT Protocol) to Neoadjuvant Chemoradiation (CROSS Protocol) in Patients with Adenocarcinoma of the Esophagus (NCT02509286) by : Changzhi Changzhi Press
Download or read book ESOPEC: Prospective Randomized Controlled Multicenter Phase III Trial Comparing Perioperative Chemotherapy (FLOT Protocol) to Neoadjuvant Chemoradiation (CROSS Protocol) in Patients with Adenocarcinoma of the Esophagus (NCT02509286) written by Changzhi Changzhi Press and published by . This book was released on 2017-01-03 with total page 38 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent randomized controlled trials comparing neoadjuvant chemoradiation plus surgery or perioperative chemotherapy plus surgery with surgery alone showed significant survival benefits for combined modality treatment of patients with localized esophageal adenocarcinoma. However, head-to-head comparisons of neoadjuvant chemoradiation and perioperative chemotherapy applying contemporary treatment protocols are lacking. The present trial was initiated to obtain valid information whether neoadjuvant chemoradiation or perioperative chemotherapy yields better survival in the treatment of localized esophageal adenocarcinoma. Proceeds from the sale of this book go to support an elderly disabled person.
Book Synopsis Perioperative Chemotherapy by : U. Metzger
Download or read book Perioperative Chemotherapy written by U. Metzger and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: One reason for failure to cure solid tumors by surgery appears to be the impossibility of controlling metastases that are present but latent at the time of operation. This failure is a common clinical experience with aggressive neoplasms. but it is not always appreciated in tumors with longer survival times. e. g .• breast and colon cancer. In addition. recent evidence indicates that after resection of a primary tumor micrometas tases from it might be enhanced by suppression of immune and reticu loendothelial functions of the host. Other factors, such as increase of coagulability and stress in the perioperative period, can also promote tumor growth. The development of new metastases might be facilitated by cells forced into the circulation during operative manipulations. Such events could be important for the outcome of treatment and it is suggested that preventive measures should be directed to this systemic component of solid tumors. Radical surgery can reduce the number of tumor cells to a subclinical 3 6 stage (10 to 10 cells) in which chemotherapy might be more effective than in advanced stages. Chemotherapy, on the other hand, might aggravate the surgical morbidity by influencing the wound healing pro cess, by decreasing the immune response, and/or by toxicity to the bone marrow and to the gastrointestinal tract, for example.
Author :Ronnie Ann Rosenthal Publisher :Springer Science & Business Media ISBN 13 :1441969993 Total Pages :1364 pages Book Rating :4.4/5 (419 download)
Book Synopsis Principles and Practice of Geriatric Surgery by : Ronnie Ann Rosenthal
Download or read book Principles and Practice of Geriatric Surgery written by Ronnie Ann Rosenthal and published by Springer Science & Business Media. This book was released on 2011-07-12 with total page 1364 pages. Available in PDF, EPUB and Kindle. Book excerpt: "In the preface to this impressive and well-produced book, the editors state that their aim is not to describe a new surgical specialty, since most surgeons will soon need to be "geriatric surgeons," but to assemble a comprehensive account that will allow "all providers of healthcare to the elderly to understand the issues involved in choosing surgery as a treatment option for their patients." This is a useful book that deserves to do well. I hope that the editors and their publisher will have the stamina to make this the first of several editions, as it is clear that updated information about surgery in the elderly will be required to keep pace with this important field." NEJM Book Review
Book Synopsis Atlas of Minimally Invasive Surgery for Lung and Esophageal Cancer by : Jun Wang
Download or read book Atlas of Minimally Invasive Surgery for Lung and Esophageal Cancer written by Jun Wang and published by Springer. This book was released on 2017-05-15 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Atlas presents a state-of-the-art review of VATS and robotic approaches to managing lung and esophageal cancers. It discusses cancer staging, physiological evaluation of patients, and patient selection for minimally invasive surgery. The atlas offers detailed descriptions of individual operations accompanied by anatomic drawings, intraoperative images, and 3-dimensional anatomic reconstructions. Written by recognized experts in the field, it provides readers with an unparalleled resource for advancing their skills in managing these cancers. It is a valuable reference work for thoracic surgeons in training as well as in practice who want to pursue minimally invasive surgery. It is unique in offering fully illustrated, step-by-step descriptions of the operative procedures.
Book Synopsis Esophageal Cancer and Barrett's Esophagus by : Prateek Sharma
Download or read book Esophageal Cancer and Barrett's Esophagus written by Prateek Sharma and published by John Wiley & Sons. This book was released on 2015-08-25 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: Esophageal Cancer and Barrett’s Esophagus, 3E, focuses on these two common and key conditions that affect the esophagus, providing expert guidance to their pathogenesis, cause, prevention, diagnosis and clinical management. Top international names in the field examine each of the many issues involved, using the very latest evidence-based research, and clear, didactic advice allows the reader to understand the best methods of diagnosis and clinical management of each condition – whether early or late stage. Well-illustrated and fully revised to include the latest in ACG/ASG/UEGW guidelines, it is the perfect consultation tool for gastroenterologists and oncologists managing patients with cancer of the esophagus. It is also ideal for teaching residents and fellows optimum patient management, and for identifying areas requiring future research.
Book Synopsis Frontiers in Radiation Oncology by : Tejinder Kataria
Download or read book Frontiers in Radiation Oncology written by Tejinder Kataria and published by BoD – Books on Demand. This book was released on 2013-07-03 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: The mode of action by radiation is postulated to be the production of double strand breaks of DNA. The repair of double strand breaks occurs through non homologous end joining through acetylation of histone proteins by histone acetyltransferases (HATs). The fixation of double strand breaks through HAT inhibitors is a promising application for radiation sensitization in the clinic. P53 is a tumour suppressor gene and its mutation has been implicated in 60% of human cancers. As one of the pivotal anticancer genes, P53 controls the transcription and translation of a series of genes. The kinetics of DNA double strand break generation and their co relation to P53 status, ATM and ARF activation are computed and modelled for understanding the potential of such research.
Book Synopsis Surgical Treatment by : René Holzheimer
Download or read book Surgical Treatment written by René Holzheimer and published by . This book was released on 2001 with total page 880 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Carbon-Ion Radiotherapy by : Hirohiko Tsujii
Download or read book Carbon-Ion Radiotherapy written by Hirohiko Tsujii and published by Springer Science & Business Media. This book was released on 2013-12-25 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book serves as a practical guide for the use of carbon ions in cancer radiotherapy. On the basis of clinical experience with more than 7,000 patients with various types of tumors treated over a period of nearly 20 years at the National Institute of Radiological Sciences, step-by-step procedures and technological development of this modality are highlighted. The book is divided into two sections, the first covering the underlying principles of physics and biology, and the second section is a systematic review by tumor site, concentrating on the role of therapeutic techniques and the pitfalls in treatment planning. Readers will learn of the superior outcomes obtained with carbon-ion therapy for various types of tumors in terms of local control and toxicities. It is essential to understand that the carbon-ion beam is like a two-edged sword: unless it is used properly, it can increase the risk of severe injury to critical organs. In early series of dose-escalation studies, some patients experienced serious adverse effects such as skin ulcers, pneumonitis, intestinal ulcers, and bone necrosis, for which salvage surgery or hospitalization was required. To preclude such detrimental results, the adequacy of therapeutic techniques and dose fractionations was carefully examined in each case. In this way, significant improvements in treatment results have been achieved and major toxicities are no longer observed. With that knowledge, experts in relevant fields expand upon techniques for treatment delivery at each anatomical site, covering indications and optimal treatment planning. With its practical focus, this book will benefit radiation oncologists, medical physicists, medical dosimetrists, radiation therapists, and senior nurses whose work involves radiation therapy, as well as medical oncologists and others who are interested in radiation therapy.
Book Synopsis Stem Cells, Pre-neoplasia, and Early Cancer of the Upper Gastrointestinal Tract by : Marnix Jansen
Download or read book Stem Cells, Pre-neoplasia, and Early Cancer of the Upper Gastrointestinal Tract written by Marnix Jansen and published by Springer. This book was released on 2016-08-29 with total page 487 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a comprehensive understanding of the evolution of pre-malignant disease, emphasizing common themes in the field, including stem cell biology and histologic modes of cancer progression between the distal esophagus and stomach. Its sixteen chapters discuss metaplastic tissue change in the upper GI, clonalexpansion of early neoplasia, stem cell dynamics in experimental models, pathology of early esophageal squamous cell carcinoma, therapeutic modalities for esophageal squamous cell carcinoma, pathology of Barrett’s esophagus, screening, early detection and novel diagnostic tools for Barrett's esophagus, clonal evolution of Barrett’s esophagus, endoscopic therapeutic modalities of early esophageal cancer, pathology of early gastric cancer, and experimental models for gastric cancer. Stem Cells, Pre-neoplasia and Early Cancer of the Upper Gastrointestinal Tract is an integrative text on both the current state of translational research on every cancer development of the upper gastrointestinal tract as well as on novel clinical diagnostic and therapeutic modalities. It highlights a rapidly growing field within cancer research and is essential reading for oncologists, biochemists and advanced graduate students alike. Springer’s Advances in Experimental Medicine and Biology series presents multidisciplinary and dynamic findings in the broad fields of experimental medicine and biology. The wide variety in topics it presents offers readers multiple perspectives on a variety of disciplines including neuroscience, microbiology, immunology, biochemistry, biomedical engineering and cancer research.
Book Synopsis Esophageal Abnormalities by : Jianyuan Chai
Download or read book Esophageal Abnormalities written by Jianyuan Chai and published by BoD – Books on Demand. This book was released on 2017-12-06 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human life relies on two basic supplies, oxygen and food. Oxygen can be utilized directly, but food has to go through a long process of digestion to become usable nutrients. The esophagus is the beginning part of this long journey. Because of its critical location, any abnormalities in this part of the body can be devastating and life-threatening and difficult to treat. This book covers many aspects of esophageal disorders, from congenital diseases to cancer. It includes 11 chapters written by highly experienced scholars from all over the world. It is our intention to provide readers an update in esophageal study and to raise the awareness how important this organ to our entire body system.
Book Synopsis Preoperative (Neoadjuvant) Chemotherapy by : Joseph Ragaz
Download or read book Preoperative (Neoadjuvant) Chemotherapy written by Joseph Ragaz and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite recent advances in adjuvant therapies of cancer, the regi mens of postoperative adjuvant chemotherapy treatment which are presently available fail to cure the majority of cancer patients. Pre operative (neoadjuvant) chemotherapy represents a new approach in drug scheduling, based on sound theoretical, pharmacokinetic, and experimental principles. The preoperative timing of chemotherapy before definitive sur gery is not a minor change in the therapy of cancer. To be successful, large numbers of practitioners and their patients must participate. Substantial alterations of many aspects of the present management of cancer will have to follow. Therefore, before such therapy can be fully and routinely implemented, results of the novel treatment and its rationale have to be carefully evaluated. In preoperative treatment, other features will likely gain impor tance. For the first time, clinicians have a chance to follow the in vivo response of the tumor exposed to preoperative chemotherapy. The subsequent histological assessment of the tumor sample may likely become an important prognostic guide, permitting more re fined individual approaches to the planning of postoperative adju vant treatment. The value of such a treatment strategy can already be appreciated in the clinical setting, as seen from the therapy of osteosarcoma. Furthermore, preoperative chemotherapy might render previously inoperable tumors operable and hence resectable with a curative intention. The preoperative reduction of tumor bulk may also effectively decrease the need for more radical operations, permitting a more uniform adoption of conservative surgery.
Book Synopsis Concise Handbook of Familial Cancer Susceptibility Syndromes by :
Download or read book Concise Handbook of Familial Cancer Susceptibility Syndromes written by and published by . This book was released on 2008 with total page 93 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Esophageal Adenocarcinoma by : Alfred K. Lam
Download or read book Esophageal Adenocarcinoma written by Alfred K. Lam and published by Humana Press. This book was released on 2018-03-30 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: This vital collection provides a unique set of techniques to explore the clinical, pathological, and research aspects of the management of patients with esophageal adenocarcinoma. Beginning with an introduction to the basic features of esophageal adenocarcinoma, the book continues with clinical protocols for the management of the cancer, pathological methods for management of the patients and research, as well as protocols for molecular research, which could aid researchers in furthering our understanding of pathogenesis as well as in identifying new targets for the treatment and prevention of adenocarcinoma. Written for the highly successful Methods in Molecular Biology series, chapters include introductions on their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and authoritative, Esophageal Adenocarcinoma: Methods and Protocols is a valuable guide to stimulate specialists from various disciplines in their continuing research into esophageal adenocarcinoma and translating that research into improving the management of this cancer of rising importance.
Book Synopsis Diagnosing and Treating Adult Cancers and Associated Impairments by : National Academies Of Sciences Engineeri
Download or read book Diagnosing and Treating Adult Cancers and Associated Impairments written by National Academies Of Sciences Engineeri and published by National Academies Press. This book was released on 2021-11-10 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer is the second leading cause of death among adults in the United States after heart disease. However, improvements in cancer treatment and earlier detection are leading to growing numbers of cancer survivors. As the number of cancer survivors grows, there is increased interest in how cancer and its treatments may affect a person's ability to work, whether the person has maintained employment throughout the treatment or is returning to work at a previous, current, or new place of employment. Cancer-related impairments and resulting functional limitations may or may not lead to disability as defined by the U.S. Social Security Administration (SSA), however, adults surviving cancer who are unable to work because of cancer-related impairments and functional limitations may apply for disability benefits from SSA. At the request of SSA, Diagnosing and Treating Adult Cancers and Associated Impairments provides background information on breast cancer, lung cancer, and selected other cancers to assist SSA in its review of the listing of impairments for disability assessments. This report addresses several specific topics, including determining the latest standards of care as well as new technologies for understanding disease processes, treatment modalities, and the effect of cancer on a person's health and functioning, in order to inform SSA's evaluation of disability claims for adults with cancer.