Advances in Endogenous and Exogenous Opioids

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Author :
Publisher : Elsevier
ISBN 13 : 1483161595
Total Pages : 520 pages
Book Rating : 4.4/5 (831 download)

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Book Synopsis Advances in Endogenous and Exogenous Opioids by : Hiroshi Takagi

Download or read book Advances in Endogenous and Exogenous Opioids written by Hiroshi Takagi and published by Elsevier. This book was released on 2013-10-22 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Endogenous and Exogenous Opioids contains the proceedings of the International Narcotic Research Conference (Satellite Symposium of the 8th International Congress of Pharmacology) held in Kyoto, Japan on July 26-30, 1981. The conference provided a forum for discussing advances that have been made in the understanding of endogenous and exogenous opioids and tackled a wide array of topics ranging from novel opiate binding sites selective for benzomorphan drugs to the purification of opioid receptors and sequellae of receptor binding. Comprised of 156 chapters, this book begins with an analysis of the interaction of opioid peptides and alkaloid opiates with mu-, delta-, and kappa-binding sites. The reader is then systematically introduced to biochemical evidence for kappa and sigma opiate receptors; the action of morphine and oxymorphone as partial agonists on the field-stimulated rat vas deferens; mechanisms of supersensitivity in the enkephalinergic system; and properties of the solubilized opiate receptor from human placenta. Subsequent chapters explore the biosynthesis of opioid peptides as well as their localization, release, and degradation; physiological and pharmacological actions of opioids; and the use of analgesia in acupuncture. Results of behavioral and clinical studies of endogenous and exogenous opioids are also presented, and the structure-activity relationships of opioids are examined. This monograph will be of interest to students, practitioners, and researchers in the fields of psychiatry and pharmacology.

Pain Management and the Opioid Epidemic

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Publisher : National Academies Press
ISBN 13 : 0309459575
Total Pages : 483 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Pain Management and the Opioid Epidemic by : National Academies of Sciences, Engineering, and Medicine

Download or read book Pain Management and the Opioid Epidemic written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-09-28 with total page 483 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.

Progress in Opioid Research

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Publisher :
ISBN 13 :
Total Pages : 754 pages
Book Rating : 4.:/5 (327 download)

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Book Synopsis Progress in Opioid Research by : John W. Holaday

Download or read book Progress in Opioid Research written by John W. Holaday and published by . This book was released on 1986 with total page 754 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Opioids in Non-Cancer Pain

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Author :
Publisher : Oxford University Press
ISBN 13 : 0199678073
Total Pages : 121 pages
Book Rating : 4.1/5 (996 download)

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Book Synopsis Opioids in Non-Cancer Pain by : Cathy Stannard

Download or read book Opioids in Non-Cancer Pain written by Cathy Stannard and published by Oxford University Press. This book was released on 2013-03-21 with total page 121 pages. Available in PDF, EPUB and Kindle. Book excerpt: This pocketbook summarizes the recent developments in this important and controversial aspect of pain management, looking at the benefits and adverse effects of opioids in non-cancer pain.

Opioids I

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Publisher : Springer Science & Business Media
ISBN 13 : 3642774601
Total Pages : 832 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis Opioids I by :

Download or read book Opioids I written by and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 832 pages. Available in PDF, EPUB and Kindle. Book excerpt: This two-volume book provides the first comprehensive survey of opioid research, a field which has accumulated a tremendous amount of literature since the identification of opioid receptors and their endogenous ligands. In more than 60 chapters experts present state-of-the-art reviews of this fascinating field, the topics ranging from molecular biology to clinical applications. Part I covers the multiplicity of opioid receptors, the chemistry of opiates and opioid peptides as well as the neurophysiology of opioids. Part II reviews a broad spectrum of physiological and behavioral functions and pharmacological actions of opioids, together with their neuroendocrinology, opioid tolerance and dependence, concluding with pathophysiological aspects and clinical use.

Medications for Opioid Use Disorder Save Lives

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Publisher : National Academies Press
ISBN 13 : 0309486483
Total Pages : 175 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Medications for Opioid Use Disorder Save Lives by : National Academies of Sciences, Engineering, and Medicine

Download or read book Medications for Opioid Use Disorder Save Lives written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2019-06-16 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt: The opioid crisis in the United States has come about because of excessive use of these drugs for both legal and illicit purposes and unprecedented levels of consequent opioid use disorder (OUD). More than 2 million people in the United States are estimated to have OUD, which is caused by prolonged use of prescription opioids, heroin, or other illicit opioids. OUD is a life-threatening condition associated with a 20-fold greater risk of early death due to overdose, infectious diseases, trauma, and suicide. Mortality related to OUD continues to escalate as this public health crisis gathers momentum across the country, with opioid overdoses killing more than 47,000 people in 2017 in the United States. Efforts to date have made no real headway in stemming this crisis, in large part because tools that already existâ€"like evidence-based medicationsâ€"are not being deployed to maximum impact. To support the dissemination of accurate patient-focused information about treatments for addiction, and to help provide scientific solutions to the current opioid crisis, this report studies the evidence base on medication assisted treatment (MAT) for OUD. It examines available evidence on the range of parameters and circumstances in which MAT can be effectively delivered and identifies additional research needed.

国立国会図書館所蔵科学技術関係欧文会議錄目錄

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Author :
Publisher :
ISBN 13 :
Total Pages : 672 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis 国立国会図書館所蔵科学技術関係欧文会議錄目錄 by : 国立国会図書館 (Japan)

Download or read book 国立国会図書館所蔵科学技術関係欧文会議錄目錄 written by 国立国会図書館 (Japan) and published by . This book was released on 1972 with total page 672 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Neurobiology of Cocaine Addiction

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Author :
Publisher : Routledge
ISBN 13 : 1317826787
Total Pages : 156 pages
Book Rating : 4.3/5 (178 download)

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Book Synopsis The Neurobiology of Cocaine Addiction by : Herman Joseph

Download or read book The Neurobiology of Cocaine Addiction written by Herman Joseph and published by Routledge. This book was released on 2014-03-18 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the use of crack on the rise in American cities, there is more need than ever to understand the biological, environmental, and social factors behind cocaine addiction, as well as the pharmacological properties of cocaine that make it such an addictive drug. The Neurobiology of Cocaine Addiction helps clinicians and researchers analyze research findings and their relevance to the clinical treatment of cocaine dependency. To do this, it looks at the whole spectrum of cocaine use, from trends in cocaine-involved deaths, hospital emergencies, arrests, and treatment admissions to the specific impact the drug has on brain function. The book reports on important findings from positron emission tomography (PET) and a “binge” pattern cocaine administration mode. This will enable you to improve your understanding of how cocaine alters the pleasure/reward system of the brain and creates new instinctual needs that displace the inherent instinctual needs of hunger and sex. By reading The Neurobiology of Cocaine Addiction, you will sharpen your knowledge of the basic actions of cocaine, the factors related to daily cocaine use, the neurobiological basis of addictive diseases, and drug-induced alterations in normal physiology. You will also learn about: the coexistence of cocaine and heroin addiction cocaine’s disruption of the endogenous opioid system QEEG and how it can play a potentially useful role in drug development and planning hypotheses of sensitization in the pathophysiology of cocaine dependence factors that predict daily cocaine use among patients in a methadone maintenance program abnormalities in brain function that persist for up to six months after last cocaine use patterns of cocaine use the importance of prospective data analysis and the limitations of a self-selective study group Clinicians, researchers, psychiatrists, and other professionals in chemical dependency and narcotics rehabilitation will turn the last page of The Neurobiology of Cocaine Addiction with a better understanding of cocaine’s addictive qualities and the characteristics of the individuals who become addicted to it. You will see what headway has been made in research at some of the nation’s top laboratories, but you will also see what remains to be done. Hopefully, you will find where you can make a contribution either at the practical level, the research level, or both.

Neurobiology of Opioids

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3642466605
Total Pages : 453 pages
Book Rating : 4.6/5 (424 download)

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Book Synopsis Neurobiology of Opioids by : Osborne F.X. Almeida

Download or read book Neurobiology of Opioids written by Osborne F.X. Almeida and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 453 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dedicated to Professor Albert Herz, a leading investigator in opioid research, this book provides comprehensive information on the biology of exogenous and endogenous opioids. Contributions by experts in the field discuss recent advances and provide systematic, up-to-date reviews of the physiology and pharmacology of opioids, as well as on the cellular and molecular mechanisms underlying opioid actions. In recognition of the diverse methodologies now available to researchers, each chapter details the approaches used to address a specific issue and provides an in-depth analysis of the data obtained by these various experimental approaches. The clinical relevance of recent findings, as well as future directions, in opioid research are also discussed. This volume thus represents a timely and invaluable sourcebook for researchers, clinicians, and students interested in opioids and peptidergic systems.

Annual Progress Report

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Author :
Publisher :
ISBN 13 :
Total Pages : 608 pages
Book Rating : 4.3/5 (129 download)

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Book Synopsis Annual Progress Report by :

Download or read book Annual Progress Report written by and published by . This book was released on 1982 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt:

NIDA Research Monograph

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Publisher :
ISBN 13 :
Total Pages : 724 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis NIDA Research Monograph by :

Download or read book NIDA Research Monograph written by and published by . This book was released on 1976 with total page 724 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Problems of Drug Dependence

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Publisher :
ISBN 13 :
Total Pages : 726 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Problems of Drug Dependence by :

Download or read book Problems of Drug Dependence written by and published by . This book was released on 1991 with total page 726 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Problems of Drug Dependence

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Author :
Publisher :
ISBN 13 :
Total Pages : 810 pages
Book Rating : 4.:/5 (4 download)

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Book Synopsis Problems of Drug Dependence by : Committee on Problems of Drug Dependence (U.S.). Scientific Meeting

Download or read book Problems of Drug Dependence written by Committee on Problems of Drug Dependence (U.S.). Scientific Meeting and published by . This book was released on 1990 with total page 810 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Problems of Drug Dependence

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Author :
Publisher :
ISBN 13 :
Total Pages : 584 pages
Book Rating : 4.3/5 ( download)

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Book Synopsis Problems of Drug Dependence by : College on Problems of Drug Dependence (U.S.). Scientific Meeting

Download or read book Problems of Drug Dependence written by College on Problems of Drug Dependence (U.S.). Scientific Meeting and published by . This book was released on 1988 with total page 584 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Opioid Analgesics

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Publisher : Springer Science & Business Media
ISBN 13 : 1489905855
Total Pages : 526 pages
Book Rating : 4.4/5 (899 download)

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Book Synopsis Opioid Analgesics by : A.F. Casy

Download or read book Opioid Analgesics written by A.F. Casy and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 526 pages. Available in PDF, EPUB and Kindle. Book excerpt: The rapidly burgeoning research of the past two decades on agonist-antagonist analgesics and opioid receptors makes this exhaustive review of opioid anal gesics particularly relevant and timely. After an introductory chapter the additional 12 chapters begin logically with morphine and congeners (4- epoxymorphinans) and end with opioid receptors. All principal chemical types of centrally acting analgesics (including endogenous opioid-like substances) and their antagonists as well as the mixed agonist-antagonists are treated thoroughly, although not always (and for good reason) in historical (chrono logical) order. A chapter on miscellaneous types (atypical structures for the most part) includes the benzimidazoles (etonitazene), aminotetralins (dezocine), tetrahydroisoquinolines (methopholine), and so on. Important aspects and correlations of chemistry, pharmacology, and biochemistry are discussed in depth. Literature citations are numerous. For educators, practicing laboratory scientists, and physicians, this scholarly review by two authors well of opioid analgesics versed in the chemistry, pharmacology, and biochemistry will be informative, stimulating, and thought-provoking. Everette L. May Medical College of Virginia Richmond, VA 23298 v Preface The history of opium predates the written word, although knowledge of its constituents dates back less than 200 years. Over the centuries its popularity for the relief of pain has waxed and waned, until today the opiates are widely recognized as excellent analgesics but with disadvantages that have impaired their use seriously. There is a clear need for a potent analgesic with minimal effects on the respiratory centers and gastrointestinal tract and preferably devoid of dependence liability.

Opioid Peptides

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Publisher :
ISBN 13 :
Total Pages : 426 pages
Book Rating : 4.:/5 (327 download)

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Book Synopsis Opioid Peptides by : Rao S. Rapaka

Download or read book Opioid Peptides written by Rao S. Rapaka and published by . This book was released on 1986 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This monograph is based upon papers and discussion from the technical review on the medicinal chemistry and molecular pharmacology of opioid peptides and the opiates which took place on September 4-6, 1984, at Bethesda, Maryland. The meeting was sponsored by the Office of Science and the Division of Preclinical Research, National Institute on Drug Abuse. The papers on molecular pharmacology, biosynthesis, and analysis of opioid peptides are presented in this volume. Those on the medical chemistry of opioid peptides appear in NIDA Research Monograph 69" [entitled Opioid peptides : medicinal chemistry] -- page iv.

Drug Addiction Research and the Health of Women

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Publisher :
ISBN 13 :
Total Pages : 600 pages
Book Rating : 4.3/5 (243 download)

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Book Synopsis Drug Addiction Research and the Health of Women by : Cora Lee Wetherington

Download or read book Drug Addiction Research and the Health of Women written by Cora Lee Wetherington and published by . This book was released on 1998 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt: