Advanced Research On Animal Venoms In China

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Advanced Research on Animal Venoms in China

Author : Ren Lai
Publisher : Mdpi AG
ISBN 13 : 9783036574349
Total Pages : 0 pages
Book Rating : 4.5/5 (743 download)

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Book Synopsis Advanced Research on Animal Venoms in China by : Ren Lai

Download or read book Advanced Research on Animal Venoms in China written by Ren Lai and published by Mdpi AG. This book was released on 2023-05-11 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recently, Chinese researchers have made significant progress in animal venom research in comprehending the diversity and complexity of these molecules and their potential applications in medicine, biotechnology, and as research tools. Advancements in 'omics' technologies such as proteomics, genomics, and transcriptomics have empowered Chinese researchers to identify and analyze venom-coded genes and proteins, revealing a kaleidoscope of novel peptide toxins with diverse functions and activities. The reprint focus on the perspective on some of the most recent and dynamic contributions of animal toxins research by Chinese researchers. The purpose of this reprint is to provide the latest work by Chinese researchers on the discovery of animal toxins, the mechanism underlining their actions, the mining of drug leads from peptide toxins, and the diagnosis and treatment of bites or stings by venomous animals.

Healing with Poisons

Author : Yan Liu
Publisher : University of Washington Press
ISBN 13 : 0295749016
Total Pages : 278 pages
Book Rating : 4.2/5 (957 download)

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Book Synopsis Healing with Poisons by : Yan Liu

Download or read book Healing with Poisons written by Yan Liu and published by University of Washington Press. This book was released on 2021-06-22 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: Open access edition: DOI 10.6069/9780295749013 At first glance, medicine and poison might seem to be opposites. But in China’s formative era of pharmacy (200–800 CE), poisons were strategically employed as healing agents to cure everything from abdominal pain to epidemic disease. Healing with Poisons explores the ways physicians, religious figures, court officials, and laypersons used toxic substances to both relieve acute illnesses and enhance life. It illustrates how the Chinese concept of du—a word carrying a core meaning of “potency”—led practitioners to devise a variety of methods to transform dangerous poisons into effective medicines. Recounting scandals and controversies involving poisons from the Era of Division to the Tang, historian Yan Liu considers how the concept of du was central to how the people of medieval China perceived both their bodies and the body politic. He also examines the wide range of toxic minerals, plants, and animal products used in classical Chinese pharmacy, including everything from the herb aconite to the popular recreational drug Five-Stone Powder. By recovering alternative modes of understanding wellness and the body’s interaction with foreign substances, this study cautions against arbitrary classifications and exemplifies the importance of paying attention to the technical, political, and cultural conditions in which substances become truly meaningful. Healing with Poisons is freely available in an open access edition thanks to TOME (Toward an Open Monograph Ecosystem) and the generous support of the University of Buffalo.

Snake Venom Metalloproteinases

Author : Jay Fox
Publisher : MDPI
ISBN 13 : 3038424269
Total Pages : 277 pages
Book Rating : 4.0/5 (384 download)

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Book Synopsis Snake Venom Metalloproteinases by : Jay Fox

Download or read book Snake Venom Metalloproteinases written by Jay Fox and published by MDPI. This book was released on 2018-07-10 with total page 277 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a printed edition of the Special Issue "Snake Venom Metalloproteinases" that was published in Toxins

Venomous Animals and Their Venoms: Venomous vertebrates

Author : Wolfgang Bücherl
Publisher :
ISBN 13 :
Total Pages : 720 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Venomous Animals and Their Venoms: Venomous vertebrates by : Wolfgang Bücherl

Download or read book Venomous Animals and Their Venoms: Venomous vertebrates written by Wolfgang Bücherl and published by . This book was released on 1968 with total page 720 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Venom and Toxin as Targeted Therapy

Author : Hang Fai (Henry) Kwok
Publisher : MDPI
ISBN 13 : 3039211897
Total Pages : 178 pages
Book Rating : 4.0/5 (392 download)

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Book Synopsis Venom and Toxin as Targeted Therapy by : Hang Fai (Henry) Kwok

Download or read book Venom and Toxin as Targeted Therapy written by Hang Fai (Henry) Kwok and published by MDPI. This book was released on 2019-10-01 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt: Targeted therapy has developed significantly in the last one and half decades, prescribing specific medications for treatment of particular diseases, such as cancer, diabetes, and heart disease. One of the most exciting recent developments in targeted therapies was the isolation of disease-specific molecules from natural resources, such as animal venoms and plant metabolites/toxins, for use as templates for new drug motif designs. In addition, the study of venom proteins/peptides and toxins naturally targeted mammalian receptors and demonstrated high specificity and selectivity towards defined ion channels of cell membranes. Research has also focsed intensely on receptors. The focus of this Special Issue of Toxins addressed the most recent advances using animal venoms, such as frog secretions, bee/ant venoms and plant/fungi toxins, as medicinal therapy. Recent advances in venom/toxin/immunotoxins for targeted cancer therapy and immunotherapy, along with using novel disease-specific venom-based protein/peptide/toxin and currently available FDA-approved drugs for combinationtreatments will be discussed. Finally, we included an overview of select promising toad/snake venom-based peptides/toxins potentially able to address the forthcoming challenges in this field. Both research and review articles proposing novelties or overviews, respectively, were published in this Special Issue after rigorous evaluation and revision by expert peer reviewers.

Cultural Forests of the Amazon

Author : William Balée
Publisher : University of Alabama Press
ISBN 13 : 0817317864
Total Pages : 289 pages
Book Rating : 4.8/5 (173 download)

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Book Synopsis Cultural Forests of the Amazon by : William Balée

Download or read book Cultural Forests of the Amazon written by William Balée and published by University of Alabama Press. This book was released on 2013-08-20 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: Winner of the Society for Economic Botany's Mary W. Klinger Book Award. Cultural Forests of the Amazon is a comprehensive and diverse account of how indigenous people transformed landscapes and managed resources in the most extensive region of tropical forests in the world. Until recently, most scholars and scientists, as well as the general public, thought indigenous people had a minimal impact on Amazon forests, once considered to be total wildernesses. William Balée’s research, conducted over a span of three decades, shows a more complicated truth. In Cultural Forests of the Amazon, he argues that indigenous people, past and present, have time and time again profoundly transformed nature into culture. Moreover, they have done so using their traditional knowledge and technology developed over thousands of years. Balée demonstrates the inestimable value of indigenous knowledge in providing guideposts for a potentially less destructive future for environments and biota in the Amazon. He shows that we can no longer think about species and landscape diversity in any tropical forest without taking into account the intricacies of human history and the impact of all forms of knowledge and technology. Balée describes the development of his historical ecology approach in Amazonia, along with important material on little-known forest dwellers and their habitats, current thinking in Amazonian historical ecology, and a narrative of his own dialogue with the Amazon and its people.

Snake Venoms

Author : P. Gopalakrishnakone
Publisher : Springer
ISBN 13 : 9789400764095
Total Pages : 0 pages
Book Rating : 4.7/5 (64 download)

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Book Synopsis Snake Venoms by : P. Gopalakrishnakone

Download or read book Snake Venoms written by P. Gopalakrishnakone and published by Springer. This book was released on 2017-02-14 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, the field of Toxinology has expanded substantially. On the one hand it studies venomous animals, plants and micro organisms in detail to understand their mode of action on targets. While on the other, it explores the biochemical composition, genomics and proteomics of toxins and venoms to understand their three interaction with life forms (especially humans), development of antidotes and exploring their pharmacological potential. Therefore, Toxinology has deep linkages with biochemistry, molecular biology, anatomy and pharmacology. In addition, there is a fast developing applied subfield, clinical toxinology, which deals with understanding and managing medical effects of toxins on human body. Given the huge impact of toxin-based deaths globally, and the potential of venom in generation of drugs for so-far incurable diseases (for example, Diabetes, Chronic Pain), the continued research and growth of the field is imminent. This has led to the growth of research in the area and the consequent scholarly output by way of publications in journals and books. Despite this ever growing body of literature within biomedical sciences, there is still no all-inclusive reference work available that collects all of the important biochemical, biomedical and clinical insights relating to Toxinology. The Handbook of Toxinology aims to address this gap and cover the field of Toxinology comprehensively.

Arthropod Venom Components and Their Potential Usage

Author : Katsuhiro Konno
Publisher : MDPI
ISBN 13 : 3039285408
Total Pages : 404 pages
Book Rating : 4.0/5 (392 download)

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Book Synopsis Arthropod Venom Components and Their Potential Usage by : Katsuhiro Konno

Download or read book Arthropod Venom Components and Their Potential Usage written by Katsuhiro Konno and published by MDPI. This book was released on 2020-03-25 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thousands of arthropod species, ranging from arachnids (spiders and scorpions) to hymenopterans (ants, bees, and wasps) and myriapods (centipedes), are venomous and use their venoms for both defense and predation. These venoms are invariably harmful to humans, and some may cause serious injuries, e.g., those from scorpions, spiders, and wasps. Arthropods’ venoms are also known as rich sources of biologically active compounds and have attracted the attention of toxin researchers for years. In this century, venom component analysis has progressed considerable due to the advances in analytical techniques, in particular, mass spectrometry and next-generation deep (DNA and RNA) sequencing. As such, proteomic and peptidomic analyses using LC–MS have enabled the full analysis of venom components, revealing a variety of novel peptide and protein toxins sequences and scaffolds, potentially useful as pharmacological research tools and for the development of highly selective peptide ligands and therapeutic leads, like chlorotoxin. Due to their specificity for numerous ion-channel subtypes, including voltage- and ligand-gated ion channels, arthropod neurotoxins have been investigated to dissect and treat neurodegenerative diseases and control epileptic syndromes. This Special Issue collects information on such progress, encouraging contributions on the chemical and biological characterization of venom components, not only peptides and proteins, but also small molecules, their mechanisms of action, and the development of venom-derived peptide leads.

Experimental and computational aspects of bioactive proteins from animal venoms: An insight into pharmacological properties and drug discovery

Download Experimental and computational aspects of bioactive proteins from animal venoms: An insight into pharmacological properties and drug discovery PDF Online Free

Author : Michelle Yap
Publisher : Frontiers Media SA
ISBN 13 : 2832545238
Total Pages : 165 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Experimental and computational aspects of bioactive proteins from animal venoms: An insight into pharmacological properties and drug discovery by : Michelle Yap

Download or read book Experimental and computational aspects of bioactive proteins from animal venoms: An insight into pharmacological properties and drug discovery written by Michelle Yap and published by Frontiers Media SA. This book was released on 2024-02-23 with total page 165 pages. Available in PDF, EPUB and Kindle. Book excerpt: Animal venoms are complex mixtures of bioactive peptides and proteins with diverse pharmacological effects. These active molecules make up the components of venom toxins responsible for many pathological outcomes in snake envenomation. Although venom toxins can be deadly, they can potentially be lifesaving once their respective pharmacological targets and mechanistic actions are better understood. For example, the discovery of captopril from Brazilian viper, Bothrops jararaca venom which has been shown to antagonise angiotensin-converting enzyme (ACE) for the treatment of hypertension.

Animal Toxins

Author : Findlay E. Russell
Publisher :
ISBN 13 :
Total Pages : 462 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Animal Toxins by : Findlay E. Russell

Download or read book Animal Toxins written by Findlay E. Russell and published by . This book was released on 1967 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Spider Venoms

Author : P. Gopalakrishnakone
Publisher : Springer
ISBN 13 : 9789400763883
Total Pages : 0 pages
Book Rating : 4.7/5 (638 download)

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Book Synopsis Spider Venoms by : P. Gopalakrishnakone

Download or read book Spider Venoms written by P. Gopalakrishnakone and published by Springer. This book was released on 2016-05-10 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, the field of Toxinology has expanded substantially. On the one hand it studies venomous animals, plants and micro organisms in detail to understand their mode of action on targets. While on the other, it explores the biochemical composition, genomics and proteomics of toxins and venoms to understand their three interaction with life forms (especially humans), development of antidotes and exploring their pharmacological potential. Therefore, Toxinology has deep linkages with biochemistry, molecular biology, anatomy and pharmacology. In addition, there is a fast developing applied subfield, clinical toxinology, which deals with understanding and managing medical effects of toxins on human body. Given the huge impact of toxin-based deaths globally, and the potential of venom in generation of drugs for so-far incurable diseases (for example, Diabetes, Chronic Pain), the continued research and growth of the field is imminent. This has led to the growth of research in the area and the consequent scholarly output by way of publications in journals and books. Despite this ever growing body of literature within biomedical sciences, there is still no all-inclusive reference work available that collects all of the important biochemical, biomedical and clinical insights relating to Toxinology. The Handbook of Toxinology aims to address this gap and cover the field of Toxinology comprehensively.

Venoms, Animal and Microbial Toxins

Author : Jean-Marc Sabatier
Publisher : Frontiers Media SA
ISBN 13 : 2889669912
Total Pages : 252 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Venoms, Animal and Microbial Toxins by : Jean-Marc Sabatier

Download or read book Venoms, Animal and Microbial Toxins written by Jean-Marc Sabatier and published by Frontiers Media SA. This book was released on 2021-07-09 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Venomous Reptiles and Their Toxins

Author : Bryan Fry
Publisher : Oxford University Press
ISBN 13 : 0190297581
Total Pages : 576 pages
Book Rating : 4.1/5 (92 download)

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Book Synopsis Venomous Reptiles and Their Toxins by : Bryan Fry

Download or read book Venomous Reptiles and Their Toxins written by Bryan Fry and published by Oxford University Press. This book was released on 2015-05-13 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: Venom research and technology has advanced greatly, rapidly transforming our knowledge of reptile venoms. Research advances, like the development of molecular systematics, provide the framework necessary to reconstruct the evolutionary history of glands and fangs. Such research developments have expanded our understanding of venom's evolution and its usefulness in therapeutic development. The results of this punctuated toxin molecular evolutionary expansion include protein neofunctionalization. While these changes may impact antivenom efficacy, this molecular diversity also facilitates their usefulness in the development of novel drug therapies. Venomous Reptiles And Their Toxins brings together the world's leading toxinologists in this comprehensive study of the entire scope of reptile venoms, from clinical effects to evolution to drug design and development. The book contains detailed applied chapters on clinical care of the envenomed patient, ineffective traditional or modern remedies, occupational considerations involved in the maintenance of institutional venomous reptile collections, veterinary care for venomous reptiles and research methods used in venom research. This book also devotes a chapter to each toxin class found in reptile venoms, detailing the full trajectory of research on the peptide or protein in question. These chapters discuss each toxin's respective role in the envenomation process through to how each has been explored for their biomedical potential. This book is a unique resource for anyone working with venomous reptiles.

Animals Through Chinese History

Author : Roel Sterckx
Publisher : Cambridge University Press
ISBN 13 : 1108428150
Total Pages : 293 pages
Book Rating : 4.1/5 (84 download)

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Book Synopsis Animals Through Chinese History by : Roel Sterckx

Download or read book Animals Through Chinese History written by Roel Sterckx and published by Cambridge University Press. This book was released on 2019 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt: This innovative collection opens a door into the rich history of animals in China. This title is also available as Open Access.

Venoms to Drugs

Author : Glenn King
Publisher : Royal Society of Chemistry
ISBN 13 : 1849736634
Total Pages : 338 pages
Book Rating : 4.8/5 (497 download)

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Book Synopsis Venoms to Drugs by : Glenn King

Download or read book Venoms to Drugs written by Glenn King and published by Royal Society of Chemistry. This book was released on 2015-02-11 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique book will provide an up to date and comprehensive account of the potential of peptides and proteins from animal venoms as possible therapeutics. The pharmaceutical industry has become increasingly interested in biologics from animal venoms as a potential source for therapeutic agents in recent years, with a particularly emphasis on peptides. To date six drugs derived from venom peptides or proteins have been approved by the FDA, with nine further agents currently being investigated in clinical trials. In addition to these drugs in approved or advanced stages of development, many more peptides and proteins are being studied in varying stages of preclinical development. Topics covered include chemistry and structural biology of animal venoms, proteomic and transcriptomic approaches to drug discovery, bioassays, high-throughput screens and target identification, and reptile, scorpion, spider and cone snail venoms as a platform for drug development. Case studies are used to illustrate methods and successes and highlight issues surrounding administration and other important lessons that have been learnt from the development of approved therapeutics based on venoms. The first text to focus on this fascinating area and bridging an important gap, this book will provide the reader with essential and current knowledge on this fast-developing area. Venoms to Drugs will find wide readership with researchers working in academia and industry working in all medicinal and pharmaceutical areas.

Venoms and Toxins: At the Crossroads of Basic, Applied and Clinical Immunology

Author : Manuela Berto Pucca
Publisher : Frontiers Media SA
ISBN 13 : 2889712362
Total Pages : 264 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Venoms and Toxins: At the Crossroads of Basic, Applied and Clinical Immunology by : Manuela Berto Pucca

Download or read book Venoms and Toxins: At the Crossroads of Basic, Applied and Clinical Immunology written by Manuela Berto Pucca and published by Frontiers Media SA. This book was released on 2021-08-26 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Handbook of Research on Advanced Phytochemicals and Plant-Based Drug Discovery

Author : Singh, Ajeet
Publisher : IGI Global
ISBN 13 : 1668451301
Total Pages : 754 pages
Book Rating : 4.6/5 (684 download)

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Book Synopsis Handbook of Research on Advanced Phytochemicals and Plant-Based Drug Discovery by : Singh, Ajeet

Download or read book Handbook of Research on Advanced Phytochemicals and Plant-Based Drug Discovery written by Singh, Ajeet and published by IGI Global. This book was released on 2022-06-24 with total page 754 pages. Available in PDF, EPUB and Kindle. Book excerpt: A great deal of interest has been generated recently in the isolation, characterization, and biological activity of phytochemicals. Phytochemicals have the potential to enhance pharmaceuticals and drug discovery. As such, there is an urgent need for current research in the global scope of phytochemicals including the chemical and physical characteristics, analytical procedures, biological activity, safety, and industrial applications. The Handbook of Research on Advanced Phytochemicals and Plant-Based Drug Discovery examines the applications of bioactive molecules from a health perspective, examining the pharmacological aspects of medicinal plants, the phytochemical and biological activities of different natural products, and ethnobotany and medicinal properties. Moreover, it presents a novel dietary approach for human disease management. Covering topics such as computer-aided drug design, government regulation, and medicinal plant taxonomy, this major reference work is beneficial to pharmacists, medical practitioners, phytologists, hospital administrators, government officials, faculty and students of higher education, librarians, researchers, and academicians.