Adrenal in Toxicology

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Publisher : CRC Press
ISBN 13 : 0748403302
Total Pages : 331 pages
Book Rating : 4.7/5 (484 download)

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Book Synopsis Adrenal in Toxicology by : Philip W. Harvey

Download or read book Adrenal in Toxicology written by Philip W. Harvey and published by CRC Press. This book was released on 1996-03-28 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: The adrenal gland is vitally important to health and secretes hormones that control many bodily processes ranging from normal metabolism to the response to stressful circumstances. The corticosteroid hormones are the basis for anti-inflammatory medicines and are very widely prescribed. Changes in the function of the adrenal gland, either naturally through stress or disease, or through the action of drugs and chemicals, can have a major impact on the body.; This text focuses on adrenal toxicity, examining how drugs and chemicals can directly and indirectly affect this gland. Coverage includes: classification of the types of adrenal and endocrine toxicity; the mechanistic and molecular basis of toxicity; reasons why the adrenal is the most common target organ in the endocrine system; drug toxicity specific to patients with adrenal disorders; drug- corticosteroid interactions; adverse drug reactions; and how the adrenal gland is vital in tolerance to toxic insult.

Adrenal Toxicology

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Publisher :
ISBN 13 : 9780429148781
Total Pages : 310 pages
Book Rating : 4.1/5 (487 download)

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Book Synopsis Adrenal Toxicology by : Philip W. Harvey

Download or read book Adrenal Toxicology written by Philip W. Harvey and published by . This book was released on 2009 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Adrenal Toxicology

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Publisher :
ISBN 13 : 9780333631690
Total Pages : pages
Book Rating : 4.6/5 (316 download)

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Book Synopsis Adrenal Toxicology by : Harvey

Download or read book Adrenal Toxicology written by Harvey and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Endocrine Toxicology

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Author :
Publisher : CRC Press
ISBN 13 : 1439810486
Total Pages : 339 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Endocrine Toxicology by : John A. Thomas

Download or read book Endocrine Toxicology written by John A. Thomas and published by CRC Press. This book was released on 1997-01-29 with total page 339 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text presents a range of topics from the molecular events surrounding hormone actions to epidemiologic studies of the effects of environmental and occupational chemicals on reproductive organs. The endocrine systems covered include the adrenal cortex, thyroid and parathyroid, gonads, and the endocrine pancreas. Of particular importance are the

Food Additives

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Publisher : CRC Press
ISBN 13 : 9780849385803
Total Pages : 36 pages
Book Rating : 4.3/5 (858 download)

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Book Synopsis Food Additives by : Fergus M. Clydesdale

Download or read book Food Additives written by Fergus M. Clydesdale and published by CRC Press. This book was released on 1996-12-23 with total page 36 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the U.S., before any additive is added to a food product the manufacturer must submit it to the FDA for approval and prove that its use has a reasonable certainty of not causing harm. The Priority-Based Assessment of Food Additives (PAFA) Database, compiled and maintained by the U.S. FDA/CFSAN (Center for Food Safety and Applied Nutrition), is a team resource for evaluating the status of all food additives. Food Additives: Toxicology, Regulation, and Properties contains a wealth of facts regarding the chemical and toxicological effects of direct food additives. It consists of identifying/administrative information for nearly 2,000 compounds that are, could be, or have been added to the U.S. food supply. Limited information is also provided for an additional 1,000 compounds. Part 1, Administrative and Chemical Information, includes data such as the CAS registry number, name of the compound, other identifying numbers, exposure to the population, and much more. The toxicological data fields are divided into three main sections: Genetic Toxicity and Cytotoxicity Information, Acute Toxicology Information, and Oral Toxicology Information. These sections contain data from toxicological studies.

The Saint-Chopra Guide to Inpatient Medicine

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Author :
Publisher : Oxford University Press, USA
ISBN 13 : 0190862807
Total Pages : 609 pages
Book Rating : 4.1/5 (98 download)

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Book Synopsis The Saint-Chopra Guide to Inpatient Medicine by : Sanjay Saint

Download or read book The Saint-Chopra Guide to Inpatient Medicine written by Sanjay Saint and published by Oxford University Press, USA. This book was released on 2018 with total page 609 pages. Available in PDF, EPUB and Kindle. Book excerpt: Preceded by: Clinical clerkship in inpatient medicine / Sanjay Saint. 3rd ed. c2010.

Recognition and Alleviation of Distress in Laboratory Animals

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Publisher : National Academies Press
ISBN 13 : 0309108179
Total Pages : 137 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Recognition and Alleviation of Distress in Laboratory Animals by : National Research Council

Download or read book Recognition and Alleviation of Distress in Laboratory Animals written by National Research Council and published by National Academies Press. This book was released on 2008-04-10 with total page 137 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientific advances in our understanding of animal physiology and behavior often require theories to be revised and standards of practice to be updated to improve laboratory animal welfare. This new book from the Institute for Laboratory Animal Research (ILAR) at the National Research Council, Recognition and Alleviation of Distress in Laboratory Animals, focuses on the stress and distress which is experienced by animals when used in laboratory research. This book aims to educate laboratory animal veterinarians; students, researchers, and investigators; animal care staff, as well as animal welfare officers on the current scientific and ethical issues associated with stress and distress in laboratory animals. It evaluates pertinent scientific literature to generate practical and pragmatic guidelines. Recognition and Alleviation of Distress in Laboratory Animals focuses specifically on the scientific understanding of the causes and the functions of stress and distress, the transformation of stress to distress, and the identification of principles for the recognition and alleviation of distress. This book discusses the role of humane endpoints in situations of distress and principles for the minimization of distress in laboratory animals. It also identifies areas in which further scientific investigation is needed to improve laboratory animal welfare in order to adhere to scientific and ethical principles that promote humane care and practice.

Endocrine and Hormonal Toxicology

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Publisher : John Wiley & Sons
ISBN 13 : 9780471970866
Total Pages : 618 pages
Book Rating : 4.9/5 (78 download)

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Book Synopsis Endocrine and Hormonal Toxicology by : Philip W. Harvey

Download or read book Endocrine and Hormonal Toxicology written by Philip W. Harvey and published by John Wiley & Sons. This book was released on 1999-06-18 with total page 618 pages. Available in PDF, EPUB and Kindle. Book excerpt: Endocrine and Hormonal Toxicology Edited by Philip W. Harvey, Kevin C. Rush and Andrew Cockburn AgrEvo UK Ltd, Saffron Walden, UK This is the first book to consider the integrated role of the classical endocrine system and hormones (including those from tissues outside the classical endocrine system) in toxicological responses. Although focusing on the latest knowledge on endocrine glands as target organs and the mechanistic and molecular basis for toxicity in these organs, Endocrine and Hormonal Toxicology has been written to cover toxicological responses at the whole body level mediated by endocrine or hormonal mechanisms. This whole body, multi-organ approach significantly broadens the relevance of this volume to toxicologists. Following an introductory section on the types of endocrine toxicity including primary, secondary and indirect mechanisms, the next section deals with endocrine organs as toxicological targets. International contributions focus on the pituitary, thyroid and parathyroids, adrenals, testes, ovaries and the pancreas, and comparative endocrine carcinogenesis. A third section of the book develops the whole body approach, in which chapters are devoted to hormonal mechanisms of toxicity to the immune, nervous, cardiovascular, gastrointestinal and reproductive systems, as well as to the liver, kidney and skin. The final section covers human and environmental health perspectives discussing endocrine disrupting chemicals, hormonal mechanisms in breast cancer and current regulatory trends in endocrine and hormonal toxicology. The comprehensive nature of Endocrine and Hormonal Toxicology makes it accessible to both specialist and general toxicologists, and to those within the fields of endocrinology, pharmacology and pathology.

Comprehensive Toxicology

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Author :
Publisher : Elsevier
ISBN 13 : 0081006128
Total Pages : 8639 pages
Book Rating : 4.0/5 (81 download)

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Book Synopsis Comprehensive Toxicology by :

Download or read book Comprehensive Toxicology written by and published by Elsevier. This book was released on 2017-12-01 with total page 8639 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Toxicology, Third Edition, Fifteen Volume Set discusses chemical effects on biological systems, with a focus on understanding the mechanisms by which chemicals induce adverse health effects. Organized by organ system, this comprehensive reference work addresses the toxicological effects of chemicals on the immune system, the hematopoietic system, cardiovascular system, respiratory system, hepatic toxicology, renal toxicology, gastrointestinal toxicology, reproductive and endocrine toxicology, neuro and behavioral toxicology, developmental toxicology and carcinogenesis, also including critical sections that cover the general principles of toxicology, cellular and molecular toxicology, biotransformation and toxicology testing and evaluation. Each section is examined in state-of-the-art chapters written by domain experts, providing key information to support the investigations of researchers across the medical, veterinary, food, environment and chemical research industries, and national and international regulatory agencies. Thoroughly revised and expanded to 15 volumes that include the latest advances in research, and uniquely organized by organ system for ease of reference and diagnosis, this new edition is an essential reference for researchers of toxicology. Organized to cover both the fundamental principles of toxicology and unique aspects of major organ systems Thoroughly revised to include the latest advances in the toxicological effects of chemicals on the immune system Features additional coverage throughout and a new volume on toxicology of the hematopoietic system Presents in-depth, comprehensive coverage from an international author base of domain experts

Veterans and Agent Orange

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Publisher : National Academies Press
ISBN 13 : 9780309075299
Total Pages : 791 pages
Book Rating : 4.0/5 (752 download)

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Book Synopsis Veterans and Agent Orange by : Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides

Download or read book Veterans and Agent Orange written by Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides and published by National Academies Press. This book was released on 1994-01-15 with total page 791 pages. Available in PDF, EPUB and Kindle. Book excerpt: Have U.S. military personnel experienced health problems from being exposed to Agent Orange, its dioxin contaminants, and other herbicides used in Vietnam? This definitive volume summarizes the strength of the evidence associating exposure during Vietnam service with cancer and other health effects and presents conclusions from an expert panel. Veterans and Agent Orange provides a historical review of the issue, examines studies of populations, in addition to Vietnam veterans, environmentally and occupationally exposed to herbicides and dioxin, and discusses problems in study methodology. The core of the book presents What is known about the toxicology of the herbicides used in greatest quantities in Vietnam. What is known about assessing exposure to herbicides and dioxin. What can be determined from the wide range of epidemiological studies conducted by different authorities. What is known about the relationship between exposure to herbicides and dioxin, and cancer, reproductive effects, neurobehavioral disorders, and other health effects. The book describes research areas of continuing concern and offers recommendations for further research on the health effects of Agent Orange exposure among Vietnam veterans. This volume will be critically important to both policymakers and physicians in the federal government, Vietnam veterans and their families, veterans organizations, researchers, and health professionals.

Endocrine Toxicology

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Publisher : Cambridge University Press
ISBN 13 : 9780521402255
Total Pages : 504 pages
Book Rating : 4.4/5 (22 download)

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Book Synopsis Endocrine Toxicology by : C. K. Atterwill

Download or read book Endocrine Toxicology written by C. K. Atterwill and published by Cambridge University Press. This book was released on 1992-04-09 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first book to deal comprehensively with endocrine toxicology. It covers the whole spectrum of known toxicant effects on the endocrine system ranging from small disturbances in hormonal secretion to full endocrine neoplasia. In each chapter, internationally recognised authorities have addressed basic endocrine physiology, current techniques for studying endocrine toxicity in vivo and in vitro, known xenobiotic-induced toxicity phenomena and the latest scientific advances in understanding the underlying molecular and cellular events. Consideration is given to important issues such as dietary factors which influence endocrine toxicity, species differences in sensitivity to toxicants, and the toxicity of hormones and drugs. The volume provides a sound basis for understanding the scientific aspects of this complex and important area of toxicology and will be a useful source of information for all those working in this field.

Endocrine System

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Publisher : Springer Science & Business Media
ISBN 13 : 3642967205
Total Pages : 373 pages
Book Rating : 4.6/5 (429 download)

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Book Synopsis Endocrine System by : T.C. Jones

Download or read book Endocrine System written by T.C. Jones and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 373 pages. Available in PDF, EPUB and Kindle. Book excerpt: The International Life Sciences Institute (ILSI) was creat ed to promote cooperative efforts toward solving critical health and safety questions involving foods, drugs, cosmet ics, chemicals, and other aspects of the environment. The officers and trustees believe that questions regarding health and safety are best resolved when government and industry rely on scientific investigations, analyses, and reviews by independent experts. Further, the scientific aspects of an issue should be examined and discussed on an international basis, separate from the political concerns of individual companies. The Institute is pleased to sponsor this set of monographs on pathology of laboratory animals. This project will help to improve the scientific application of the techniques of pathology to the evaluation of substances in our environ ment. The worldwide distribution of the authors, editors, and editorial board encourages the expectation that inter national communication and cooperation will also be strengthened. Alex Malaspina President International Life Sciences Institute Preface This book on the endocrine system is Volume I of a set of reference books on pathology of laboratory animals, prepared by the Interna tional Life Sciences Institute in response to recommendations from its Committee on Pathology and Toxicology. One aim is to provide infor mation which will be useful to pathologists, especially those involved in studies on the safety of foods, drugs, chemicals, and other sub stances in the environment.

The Adrenal Cortex

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Publisher :
ISBN 13 :
Total Pages : 344 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Adrenal Cortex by : Gavin P. Vinson

Download or read book The Adrenal Cortex written by Gavin P. Vinson and published by . This book was released on 1992 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Reproductive and Developmental Toxicology

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Publisher : Academic Press
ISBN 13 : 9780123820334
Total Pages : 1220 pages
Book Rating : 4.8/5 (23 download)

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Book Synopsis Reproductive and Developmental Toxicology by : Ramesh C. Gupta

Download or read book Reproductive and Developmental Toxicology written by Ramesh C. Gupta and published by Academic Press. This book was released on 2011-04-04 with total page 1220 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reproductive toxicology is a complex subject dealing with three components—parent, placenta, and fetus—and the continuous changes that occur in each. Reproductive and Developmental Toxicology is a comprehensive and authoritative resource providing the latest literature enriched with relevant references describing every aspect of this area of science. It addresses a broad range of topics including nanoparticles and radiation, gases and solvents, smoking, alcohol and drugs of abuse, food additives, nutraceuticals and pharmaceuticals, and metals, among others. With a special focus on placental toxicity, this book is the only available reference to connect the three key risk stages, and is the only resource to include reproductive and developmental toxicity in domestic animals, fish, and wildlife. Provides a complete, integrated source of information on the key risk stages during reproduction and development Includes coverage of emerging science such as stem cell application, toxicoproteomics, metabolomics, phthalates, infertility, teratogenicity, endocrine disruption, surveillance and regulatory considerations, and risk assessment Offers diverse and unique in vitro and in vivo toxicity models for reproductive and developmental toxicity testing in a user-friendly format that assists in comparative analysis

Toxicology

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Publisher : Academic Press
ISBN 13 : 0080543111
Total Pages : 1355 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Toxicology by : Hans Marquardt

Download or read book Toxicology written by Hans Marquardt and published by Academic Press. This book was released on 1999-10-05 with total page 1355 pages. Available in PDF, EPUB and Kindle. Book excerpt: Toxicology is a comprehensive text for researchers and graduate students in toxicology and public health. It addresses every aspect of the field, starting with the fundamentals and incorporating such areas as organ toxicology, applications, and environmental toxicology. In addition to covering the traditional subject matter of toxicology, special emphasis has been placed on recent areas of interest, such as risk assessment, apoptosis, and methodical developments. Key Features * Comprehensive text, covering all aspects of the field of toxicology * Analyzes the importance of toxicokinetics and metabolism as well as cellular targets for the mechanisms of toxic effects * Identifies the various classes of chemical compounds responsible for the toxic effects * Describes the approaches and methods used by various disciplines which investigate toxic effects and their prevention * Adapted from a very successful German text, this edition is completely revised and expanded * The text is well illustrated with diagrams, charts, and tables

How Tobacco Smoke Causes Disease

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Publisher :
ISBN 13 :
Total Pages : 728 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis How Tobacco Smoke Causes Disease by :

Download or read book How Tobacco Smoke Causes Disease written by and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.

Dictionary of Toxicology

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Author :
Publisher : Springer Nature
ISBN 13 : 9819992834
Total Pages : 1094 pages
Book Rating : 4.8/5 (199 download)

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Book Synopsis Dictionary of Toxicology by : AB Pant

Download or read book Dictionary of Toxicology written by AB Pant and published by Springer Nature. This book was released on with total page 1094 pages. Available in PDF, EPUB and Kindle. Book excerpt: