ADP-Ribosylation Reactions

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Publisher : Springer Science & Business Media
ISBN 13 : 1441987185
Total Pages : 438 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis ADP-Ribosylation Reactions by : Guy G. Poirier

Download or read book ADP-Ribosylation Reactions written by Guy G. Poirier and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph is dedicated to one of the discoverers of poly(ADP ribose), Professor Paul Mandel, from the Centre de Neurochimie in Strasbourg. We would like to congratulate him for his distinguished contributions to the field of poly(ADP-ribosyl)ation and express our gratitude for his support in the last years and particularly for his encouragement for the organization of this meeting. Poly(ADP-ribose) was discovered more than 25 years ago. Since then, excellent progress has been made on the study of the mechanisms of poly(ADP ribose) reaction. The last five years have been particularly exciting since the development of various molecular biology techniques has revealed the complex nature of this multifunctional enzyme. Looking at the contributions presented at this meeting, it becomes obvious that more work at the molecular level is needed. Most likely, these experiments will shed some light on the functions of poly(ADP-ribose), but further ~iophysical studies will still be required to fully understand this complex enzymatic system.

ADP-Ribosylation Reactions

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Author :
Publisher : Elsevier
ISBN 13 : 0323142990
Total Pages : 725 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis ADP-Ribosylation Reactions by : Osamu Hayaishi

Download or read book ADP-Ribosylation Reactions written by Osamu Hayaishi and published by Elsevier. This book was released on 2012-12-02 with total page 725 pages. Available in PDF, EPUB and Kindle. Book excerpt: ADP-Ribosylation Reactions: Biology and Medicine deals with the biochemical and physiological aspects of poly(ADP-ribose) and ADP-ribosylation of proteins. Topics covered range from pyridine nucleotide metabolism and ADP-ribosylation to the structure and properties of poly(ADP-ribose), along with acceptor proteins of poly(ADP-ribose). ADP-ribosyl protein linkages and poly(ADP-ribose) synthetase are also discussed. Comprised of 39 chapters, this book begins with a historical background on the discovery of poly(ADP-ribose) and the significance of poly- and mono(ADP-ribosyl)ation reactions in molecular biology. The next section explores the role of ADP-ribosylation in NAD metabolism, paying particular attention to poly(ADP-ribose) synthetase-DNA interaction and the link between chromatin structure and poly(ADP-ribosyl)ation. Subsequent chapters focus on subfractions and subcellular distribution of mono(ADP-ribosyl) proteins in eukaryotic cells; polyadenylylation and ADP-ribosylation of reovirus proteins; poly(ADP-ribose) synthesis in plants; and immunohistochemistry of poly(ADP-ribose). The final chapter analyzes the ADP-ribosylation activity of toxin A and exoenzyme S in Pseudomonas aeruginosa. This monograph is written for students, practitioners, and researchers in fields such as molecular biology, medical chemistry, and biochemistry.

ADP-Ribosylation Reactions

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Publisher : Springer Science & Business Media
ISBN 13 : 1441987401
Total Pages : 156 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis ADP-Ribosylation Reactions by : R. Alvarez-Gonzalez

Download or read book ADP-Ribosylation Reactions written by R. Alvarez-Gonzalez and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: This special issue of Molecular and Cellular Biochemistry contains twenty-two selected research papers and reviews from a total of one hundred and ten presentations given at the 12th International Symposium on ADP-ribosylation Reactions: From Bacterial Pathogenesis to Cancer, held in Cancun, Mexico, May 10-14, 1997. The Symposium was hosted by the Sociedad Mexicana de Bioquimica and was sponsored by the University of North Texas Health Science Center, Fort Worth, TX, USA. This volume provides a state-of-the-art source of information for basic scientists and clinicians who are interested in the molecular, biochemical, and cellular aspects of protein-(ADP-ribose) transfer reactions in human health and disease.

ADP-ribosylation Reactions

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Publisher :
ISBN 13 :
Total Pages : 744 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis ADP-ribosylation Reactions by : Osamu Hayaishi

Download or read book ADP-ribosylation Reactions written by Osamu Hayaishi and published by . This book was released on 1982 with total page 744 pages. Available in PDF, EPUB and Kindle. Book excerpt:

ADP-Ribose Transfer Reactions

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1461585074
Total Pages : 543 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis ADP-Ribose Transfer Reactions by : Myron K. Jacobson

Download or read book ADP-Ribose Transfer Reactions written by Myron K. Jacobson and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 543 pages. Available in PDF, EPUB and Kindle. Book excerpt: Current interest in NAD (Nicotinamide adenine dinucleotide) in biological systems focuses on its role in ADP-ribose transfer reactions. These appear to be fundamentally involved in the regulation of many physiological processes. The contributions in this monograph thus represent the range of research in the very active investigation of niacin metabolism. The major topics covered are: ??? - Enzymology of ADP-Ribosylation - ADP-Ribosylation and Chromatin Function - Carcinogenesis and Differentiation - NAD Metabolism and Chemotherapy - ADP-Ribosylation and Signal Transduction - Molecular Genetic Approaches to ADP-Ribosylation

ADP-Ribosylation of Proteins

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Publisher : Springer Science & Business Media
ISBN 13 : 3642705898
Total Pages : 594 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis ADP-Ribosylation of Proteins by : Felix R. Althaus

Download or read book ADP-Ribosylation of Proteins written by Felix R. Althaus and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 594 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an update on recent advances in the field of ADP ribosylation reactions. The individual chapters represent the synopses of contributions which were presented at the Seventh International Symposium on ADP-Ribosylation Reactions, held in Vitznau, Switzer land, from September 23 to 27, 1984. This volume covers new devel opments in the field since the last meeting was held on this topic in 1982, in Tokyo. Therefore, the present text is not meant to form a comprehensive account of a specialized research area, but encompasses a collection of state-of-the-art reports from the vast majority of laboratories currently involved in ADP-ribosylation work. For the sake of rapid publication, the editorial policy was to ensure easy accessibility of information contained in individual articles rather than to provide elaborate cross references or reference to work published prior to 1982. However, a detailed subject index will help the reader find complementary information. The enzymes of ADP-ribose metabolism have not yet acquired universally acceptable trivial names and the Enzyme Commission has not yet defmitely decided on formal appellations. Consequently, a variety of names for the nuclear enzyme appear in this book, including nuc1ear(ADP-ribosyl)transferase, poly(ADP-ribose) polymerase, or synthetase or synthase. Hopefully, a common convention will soon be established. The Seventh International Symposium on ADP-Ribosylation Reac tions was only possible because of the generous support which we have been given by our sponsors, listed below.

ADP-Ribosylation: Metabolic Effects and Regulatory Functions

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Publisher : Springer Science & Business Media
ISBN 13 : 1461526140
Total Pages : 243 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis ADP-Ribosylation: Metabolic Effects and Regulatory Functions by : Joel Moss

Download or read book ADP-Ribosylation: Metabolic Effects and Regulatory Functions written by Joel Moss and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt: Considering the current interest in cellular regulation and intracellular signalling systems, it is surprising that the contribution of ADP-ribosylation reactions to the modulation of a variety of specific cell processes, in parallel with other post-translational modifications such as phosphorylation, has not been generally recognized. While it is not feasible to cover all aspects of ADP-ribosylation, the thirty-one articles contained in this volume provide a valuable overview of recent progress in the field within the context of cell control mechanisms. For the convenience of the reader, the various topics have been grouped into several sections: (a) poly(ADP-ribosyl)ation; (b) mono-ADP-ribosylation; (c) toxin mono-ADP-ribosylation; (d) inhibitors and activators; (e) protein modification with ADP-ribose and its analogues; and (f) non-modification forms of ADP-ribose. The contents of the individual chapters reflect the ideas of the contributors, many of whom have spent their careers attempting to resolve the biological functions of ADP-ribosylation. We hope that this publication will serve as a useful reference for those investigators that are new to the area as well as those who are actively studying ADP-ribosylation.

Poly(ADP-Ribosyl)ation

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Publisher : Springer Science & Business Media
ISBN 13 : 0387360050
Total Pages : 260 pages
Book Rating : 4.3/5 (873 download)

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Book Synopsis Poly(ADP-Ribosyl)ation by : Alexander Bürkle

Download or read book Poly(ADP-Ribosyl)ation written by Alexander Bürkle and published by Springer Science & Business Media. This book was released on 2008-01-11 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the most comprehensive, up-to-date reference on this post-translational modification of proteins, which is intimately linked with DNA repair, maintenance of genomic stability, transcriptional regulation, cell death and a variety of other cellular phenomena as well as with a variety of pathophysiological conditions, including ischemia-reperfusion damage, Parkinson’s disease, Type I diabetes mellitus, hemorrhagic and septic shock and other inflammatory conditions. Richly illustrated, it offers 19 chapters written by international experts.

Poly Adp-Ribosylation Reactions

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Publisher : International Thomson Publishing Services
ISBN 13 : 9780412133916
Total Pages : 250 pages
Book Rating : 4.1/5 (339 download)

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Book Synopsis Poly Adp-Ribosylation Reactions by : Gilbert De Murcia

Download or read book Poly Adp-Ribosylation Reactions written by Gilbert De Murcia and published by International Thomson Publishing Services. This book was released on 1997-01-01 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt:

ADP-ribosylation of Proteins

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Publisher : Springer
ISBN 13 : 9783540177340
Total Pages : 237 pages
Book Rating : 4.1/5 (773 download)

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Book Synopsis ADP-ribosylation of Proteins by : Felix R. Althaus

Download or read book ADP-ribosylation of Proteins written by Felix R. Althaus and published by Springer. This book was released on 1987-01-01 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1966, a paper entitled "On the formation of a novel adenylylic compound by enzymatic extracts of liver nuclei" from Paul Mandel's laboratory in Strasbourg, France, planted the seed for a rapidly growing new field of biological research focusing on ADP-ribosylation reactions. The development of this field over the past 2 decades reflects very much a modern trend of biological research. As more detailed knowledge accumulates, enigmatic phenomena turn into concepts which create their own enigmata. This process tends to favor the development of multiple, seemingly disconnected, research lines until simplicity emerges from chaos and unifying concepts substitute for controversy. It appears that the field of ADP-ribosylation reactions has not yet attained this latter stage. For example, with the identification of two different classes of ADP-ribosylation reactions, i.e., mono-ADP-ribosyla­ tion and poly-ADP-ribosylation reactions, the field split very early into two separate branches of research. With the present volume, we have divided the task of reviewing these two classes of ADP­ ribosylation accordingly, although their coexistence in eukaryotes may involve a closer functional linkage than hitherto recognized.

ADP-ribosylation reactions: mechanisms and biological significance

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (17 download)

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Book Synopsis ADP-ribosylation reactions: mechanisms and biological significance by :

Download or read book ADP-ribosylation reactions: mechanisms and biological significance written by and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

From DNA Damage and Stress Signalling to Cell Death

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Publisher : Oxford University Press, USA
ISBN 13 :
Total Pages : 282 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis From DNA Damage and Stress Signalling to Cell Death by : Gilbert de Murcia

Download or read book From DNA Damage and Stress Signalling to Cell Death written by Gilbert de Murcia and published by Oxford University Press, USA. This book was released on 2000 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: This study provides an overview of the physiological role of poly ADP-ribose polymerase in the cell. Its major function is to protect the genome from damage and it therefore has pharmaceutical potential.

Mass Spectrometry-Based Chemical Proteomics

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Publisher : John Wiley & Sons
ISBN 13 : 1118970217
Total Pages : 448 pages
Book Rating : 4.1/5 (189 download)

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Book Synopsis Mass Spectrometry-Based Chemical Proteomics by : W. Andy Tao

Download or read book Mass Spectrometry-Based Chemical Proteomics written by W. Andy Tao and published by John Wiley & Sons. This book was released on 2019-07-10 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: PROVIDES STRATEGIES AND CONCEPTS FOR UNDERSTANDING CHEMICAL PROTEOMICS, AND ANALYZING PROTEIN FUNCTIONS, MODIFICATIONS, AND INTERACTIONS—EMPHASIZING MASS SPECTROMETRY THROUGHOUT Covering mass spectrometry for chemical proteomics, this book helps readers understand analytical strategies behind protein functions, their modifications and interactions, and applications in drug discovery. It provides a basic overview and presents concepts in chemical proteomics through three angles: Strategies, Technical Advances, and Applications. Chapters cover those many technical advances and applications in drug discovery, from target identification to validation and potential treatments. The first section of Mass Spectrometry-Based Chemical Proteomics starts by reviewing basic methods and recent advances in mass spectrometry for proteomics, including shotgun proteomics, quantitative proteomics, and data analyses. The next section covers a variety of techniques and strategies coupling chemical probes to MS-based proteomics to provide functional insights into the proteome. In the last section, it focuses on using chemical strategies to study protein post-translational modifications and high-order structures. Summarizes chemical proteomics, up-to-date concepts, analysis, and target validation Covers fundamentals and strategies, including the profiling of enzyme activities and protein-drug interactions Explains technical advances in the field and describes on shotgun proteomics, quantitative proteomics, and corresponding methods of software and database usage for proteomics Includes a wide variety of applications in drug discovery, from kinase inhibitors and intracellular drug targets to the chemoproteomics analysis of natural products Addresses an important tool in small molecule drug discovery, appealing to both academia and the pharmaceutical industry Mass Spectrometry-Based Chemical Proteomics is an excellent source of information for readers in both academia and industry in a variety of fields, including pharmaceutical sciences, drug discovery, molecular biology, bioinformatics, and analytical sciences.

Study of ADP-ribosylation Reactions Catalyzed by Bacterial Toxins Using Substituted Guanylhydrazones as Substrates

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Publisher :
ISBN 13 :
Total Pages : 216 pages
Book Rating : 4.:/5 (23 download)

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Book Synopsis Study of ADP-ribosylation Reactions Catalyzed by Bacterial Toxins Using Substituted Guanylhydrazones as Substrates by : Jayashree Narayanan

Download or read book Study of ADP-ribosylation Reactions Catalyzed by Bacterial Toxins Using Substituted Guanylhydrazones as Substrates written by Jayashree Narayanan and published by . This book was released on 1989 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt:

B Vitamins and Folate

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Publisher : Royal Society of Chemistry
ISBN 13 : 1849733694
Total Pages : 890 pages
Book Rating : 4.8/5 (497 download)

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Book Synopsis B Vitamins and Folate by : Victor R. Preedy

Download or read book B Vitamins and Folate written by Victor R. Preedy and published by Royal Society of Chemistry. This book was released on 2013 with total page 890 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by an expert team, this research compilation provides a fascinating insight into the scientific knowledge around these compounds for health and nutritional scientists.

ADP-ribosylation in Animal Tissues

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Publisher : Springer Science & Business Media
ISBN 13 : 9780306455100
Total Pages : 0 pages
Book Rating : 4.4/5 (551 download)

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Book Synopsis ADP-ribosylation in Animal Tissues by : Friedrich Haag

Download or read book ADP-ribosylation in Animal Tissues written by Friedrich Haag and published by Springer Science & Business Media. This book was released on 1997 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Documents the first conference on the topic, called in response to opportunities opened by the molecular characterization of the first mammalian mono(ADP-ribosyl)transferase enzyme from rabbit skeletal muscles, and the subsequent realization that one had already been to hand in a well-studied surfac

Covalent Modification of Proteins by ADP-ribosylation

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (596 download)

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Book Synopsis Covalent Modification of Proteins by ADP-ribosylation by : Jozsef C. Gaal

Download or read book Covalent Modification of Proteins by ADP-ribosylation written by Jozsef C. Gaal and published by . This book was released on 1986 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: