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Acousto Optic Imaging In Diffuse Media Using Pulsed Ultrasound And The Photorefractive Effect
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Book Synopsis Acousto-optic Imaging in Diffuse Media Using Pulsed Ultrasound and the Photorefractive Effect by : Lei Sui
Download or read book Acousto-optic Imaging in Diffuse Media Using Pulsed Ultrasound and the Photorefractive Effect written by Lei Sui and published by . This book was released on 2006 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: Abstract: Acousto-optic imaging (AOI) in optically diffuse media is a hybrid imaging modality in which a focused ultrasound beam is used to locally phase modulate light inside of turbid media. The modulated optical field carries with it information about the optical properties in the region where the light and sound interact. The motivation for the development of AOI systems is to measure optical properties at large depths within biological tissue with high spatial resolution.
Book Synopsis Photorefractive Crystal-based Acousto-optic Imaging in the Near-infrared and Its Applications by : Puxiang Lai
Download or read book Photorefractive Crystal-based Acousto-optic Imaging in the Near-infrared and Its Applications written by Puxiang Lai and published by . This book was released on 2011 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: Abstract:Acousto-optic (AO) sensing and imaging (AOI) is a dual-wave modality that combines ultrasound with diffusive light to measure and/or image the optical properties of optically diffusive media, including biological tissues such as breast and brain. The light passing through a focused ultrasound beam undergoes a phase modulation at the ultrasound frequency that is detected using an adaptive interferometer scheme employing a GaAs photorefractive crystal (PAC). The PRC-based AO system operating at 1064 nm is described, along with the underlying theory, validating experiments, characterization, and optimization of this sensing and imaging apparatus. The spatial resolution of AO sensing, which is determined by spatial dimensions of the ultrasound beam or pulse, can be sub-millimeter for megahertz-frequency sound waves. A modified approach for quantifying the optical properties of diffuse media with AO sensing employs the ratio of AO signals generated at two different ultrasound focal pressures. The resulting "pressure contrast signal" (POE), once calibrated for a particular set of pressure pulses, yields a direct measure of the spatially averaged optical transport attenuation coefficient within the interaction volume between light and sound. This is a significant improvement over current AO sensing methods since it produces a quantitative measure of the optical properties of optically diffuse media without a priori knowledge of the background illumination. It can also be used to generate images based on spatial variations in both optical scattering and absorption. Finally, the AO sensing system is modified to monitor the irreversible optical changes associated with the tissue heating from high intensity focused ultrasound (HIFU) therapy, providing a powerful method for noninvasively sensing the onset and growth of thermal lesions in soft tissues. A single HIFU transducer is used to simultaneously generate tissue damage and pump the AO interaction. Experimental results performed in excised chicken breast demonstrate that AO sensing can identify the onset and growth of lesion formation in real time and, when used as feedback to guide exposure parameters, results in more predictable lesion formation.
Book Synopsis Biomedical Photonics Handbook, Second Edition by : Tuan Vo-Dinh
Download or read book Biomedical Photonics Handbook, Second Edition written by Tuan Vo-Dinh and published by CRC Press. This book was released on 2014-07-29 with total page 894 pages. Available in PDF, EPUB and Kindle. Book excerpt: Shaped by Quantum Theory, Technology, and the Genomics Revolution The integration of photonics, electronics, biomaterials, and nanotechnology holds great promise for the future of medicine. This topic has recently experienced an explosive growth due to the noninvasive or minimally invasive nature and the cost-effectiveness of photonic modalities in medical diagnostics and therapy. The second edition of the Biomedical Photonics Handbook presents fundamental developments as well as important applications of biomedical photonics of interest to scientists, engineers, manufacturers, teachers, students, and clinical providers. The second volume, Biomedical Diagnostics, focuses on biomedical diagnostic technologies and their applications from the bench to the bedside. Represents the Collective Work of over 150 Scientists, Engineers, and Clinicians Designed to display the most recent advances in instrumentation and methods, as well as clinical applications in important areas of biomedical photonics to a broad audience, this three-volume handbook provides an inclusive forum that serves as an authoritative reference source for a broad audience involved in the research, teaching, learning, and practice of medical technologies. What’s New in This Edition: A wide variety of photonic biochemical sensing technologies have already been developed for clinical monitoring of physiological parameters, such as blood pressure, blood chemistry, pH, temperature, and the presence of pathological organisms or biochemical species of clinical importance. Advanced photonic detection technologies integrating the latest knowledge of genomics, proteomics and metabolomics allow sensing of early disease state biomarkers, thus revolutionizing the medicine of the future. Nanobiotechnology has opened new possibilities for detection of biomarkers of disease, imaging single molecules and in situ diagnostics at the single cell level. In addition to these state-of-the art advancements, the second edition contains new topics and chapters including: • Fiber Optic Probe Design • Laser and Optical Radiation Safety • Photothermal Detection • Multidimensional Fluorescence Imaging • Surface Plasmon Resonance Imaging • Molecular Contrast Optical Coherence Tomography • Multiscale Photoacoustics • Polarized Light for Medical Diagnostics • Quantitative Diffuse Reflectance Imaging • Interferometric Light Scattering • Nonlinear Interferometric Vibrational Imaging • Multimodality Theranostics Nanoplatforms • Nanoscintillator-Based Therapy • SERS Molecular Sentinel Nanoprobes • Plasmonic Coupling Interference Nanoprobes Comprised of three books: Volume I: Fundamentals, Devices, and Techniques; Volume II: Biomedical Diagnostics; and Volume III: Therapeutics and Advanced Biophotonics, this second edition contains eight sections, and provides introductory material in each chapter. It also includes an overview of the topic, an extensive collection of spectroscopic data, and lists of references for further reading.
Book Synopsis Biomedical Optics by : Lihong V. Wang
Download or read book Biomedical Optics written by Lihong V. Wang and published by John Wiley & Sons. This book was released on 2012-09-26 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: This entry-level textbook, covering the area of tissue optics, is based on the lecture notes for a graduate course (Bio-optical Imaging) that has been taught six times by the authors at Texas A&M University. After the fundamentals of photon transport in biological tissues are established, various optical imaging techniques for biological tissues are covered. The imaging modalities include ballistic imaging, quasi-ballistic imaging (optical coherence tomography), diffusion imaging, and ultrasound-aided hybrid imaging. The basic physics and engineering of each imaging technique are emphasized. A solutions manual is available for instructors; to obtain a copy please email the editorial department at [email protected].
Book Synopsis Optical Techniques in Regenerative Medicine by : Stephen P. Morgan
Download or read book Optical Techniques in Regenerative Medicine written by Stephen P. Morgan and published by Taylor & Francis. This book was released on 2016-04-19 with total page 445 pages. Available in PDF, EPUB and Kindle. Book excerpt: In regenerative medicine, tissue engineers largely rely on destructive and time-consuming techniques that do not allow in situ and spatial monitoring of tissue growth. Furthermore, once the therapy is implanted in the patient, clinicians are often unable to monitor what is happening in the body. To tackle these barriers, optical techniques have bee
Download or read book Photons Plus Ultrasound written by and published by . This book was released on 2005 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Dissertation Abstracts International by :
Download or read book Dissertation Abstracts International written by and published by . This book was released on 2006 with total page 780 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Modelling and Control in Biomedical Systems 2006 by : David Dagan Feng
Download or read book Modelling and Control in Biomedical Systems 2006 written by David Dagan Feng and published by Elsevier. This book was released on 2006-09-19 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modelling and Control in Biomedical Systems (including Biological Systems) was held in Reims, France, 20-22 August 2006. This Symposium was organised by the University of Reims Champagne Ardenne and the Société de l’Electricité, de l’Electronique et des TIC (SEE). The Symposium attracted practitioners in engineering, information technology, mathematics, medicine and biology, and other related disciplines, with authors from 24 countries. Besides the abstracts of the four plenary lectures, this volume contains the 92 papers that were presented by their authors at the Symposium. The papers included two invited keynote presentations given by internationally prominent and well-recognised research leaders: Claudio Cobelli, whose talk is titled "Dynamic modelling in diabetes: from whole body to genes"; and Irving J. Bigio, whose talk is titled "Elastic scattering spectroscopy for non-invasive detection of cancer". Two prestigious industrial speakers were also invited to give keynote presentations: Terry O'Brien from LIDCO, whose talk is titled "LIDCO: From the laboratory to protocolized goal directed therapy"; and Lorenzo Quinzio of Philips, whose talk is titled "Clinical decision support in monitoring and information systems". A valuable source of information on the state-of- the-art in Modelling and Control in Biomedical Systems Including abstracts of four plenary lectures, and 92 papers presented by their authors
Book Synopsis 8th International Symposium on Therapeutic Ultrasound by : Emad S. Ebbini
Download or read book 8th International Symposium on Therapeutic Ultrasound written by Emad S. Ebbini and published by American Inst. of Physics. This book was released on 2009-05-13 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: The proceedings offer a comprehensive view of the state-of-the-art of Therapeutic Ultrasound from the basic science to device technology to clinical practice. Papers describing new therapies of cancer and other tissue abnormalities using innovative device concepts are included. In particular, advanced transducer technologies for noninvasive or minimally invasive delivery of therapeutic ultrasound under image guidance are described by a significant number of papers within the proceedings. The proceedings also include papers on the use of ultrasound in enhancing drug delivery with and without the use of ultrasound contrast agents. In addition, standards and quality assurance issues are addressed by a number of papers. Finally, clinical and pre-clinical in vivo studies are also described.
Book Synopsis Handbook of Biomedical Optics by : David A. Boas
Download or read book Handbook of Biomedical Optics written by David A. Boas and published by CRC Press. This book was released on 2016-04-19 with total page 816 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomedical optics holds tremendous promise to deliver effective, safe, non- or minimally invasive diagnostics and targeted, customizable therapeutics. Handbook of Biomedical Optics provides an in-depth treatment of the field, including coverage of applications for biomedical research, diagnosis, and therapy. It introduces the theory and fundamental
Book Synopsis Ultrasound-mediated Optical Imaging and Focusing in Scattering Media by : Yuta Suzuki
Download or read book Ultrasound-mediated Optical Imaging and Focusing in Scattering Media written by Yuta Suzuki and published by . This book was released on 2014 with total page 82 pages. Available in PDF, EPUB and Kindle. Book excerpt: Because of its non-ionizing and molecular sensing nature, light has been an attractive tool in biomedicine. Scanning an optical focus allows not only high-resolution imaging but also manipulation and therapy. However, due to multiple photon scattering events, conventional optical focusing using an ordinary lens is limited to shallow depths of one transport mean free path (lt'), which corresponds to approximately 1 mm in human tissue. To overcome this limitation, ultrasonic modulation (or encoding) of diffuse light inside scattering media has enabled us to develop both deep-tissue optical imaging and focusing techniques, namely, ultrasound-modulated optical tomography (UOT) and time-reversed ultrasonically encoded (TRUE) optical focusing. While UOT measures the power of the encoded light to obtain an image, TRUE focusing generates a time-reversed (or phase-conjugated) copy of the encoded light, using a phase-conjugate mirror to focus light inside scattering media beyond 1 lt'. However, despite extensive progress in both UOT and TRUE focusing, the low signal-to-noise ratio in encoded-light detection remains a challenge to meeting both the speed and depth requirements for in vivo applications. This dissertation describes technological advancements of both UOT and TRUE focusing, in terms of their signal detection sensitivities, operational depths, and operational speeds. The first part of this dissertation describes sensitivity improvements of encoded-light detection in UOT, achieved by using a large area (~5 cm x 5 cm) photorefractive polymer. The photorefractive polymer allowed us to improve the detection etendue by more than 10 times that of previous detection schemes. It has enabled us to resolve absorbing objects embedded inside diffused media thicker than 80 lt', using moderate light power and short ultrasound pulses. The second part of this dissertation describes energy enhancement and fluorescent excitation using TRUE focusing in turbid media, using photorefractive materials as the phase-conjugate mirrors. By using a large-area photorefractive polymer as the phase-conjugate mirror, we boosted the focused optical energy by ~40 times over the output of a previously used photorefractive Bi12SiO20 crystal. Furthermore, using both a photorefractive polymer and a Bi12SiO20 crystal as the phase-conjugate mirrors, we show direct visualization and dynamic control of TRUE focus, and demonstrate fluorescence imaging in a thick turbid medium. The last part of this dissertation describes improvements in the scanning speed of a TRUE focus, using digital phase-conjugate mirrors in both transmission and reflection modes. By employing a multiplex recording of ultrasonically encoded wavefronts in transmission mode, we have accelerated the generation of multiple TRUE foci, using frequency sweeping of both ultrasound and light. With this technique, we obtained a 2-D image of a fluorescent target centered inside a turbid sample having a thickness of 2.4 lt'. Also, by gradually moving the focal position in reflection mode, we show that the TRUE focal intensity is improved, and can be continuously scanned to image fluorescent targets in a shorter time.
Download or read book Optics Letters written by and published by . This book was released on 2005 with total page 584 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Acoustics Today written by and published by . This book was released on 2007 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Ultrasound-modulated Optical Imaging Using a Photorefractive Interferometer and a Powerful Long Pulse Laser by : Guy Rousseau
Download or read book Ultrasound-modulated Optical Imaging Using a Photorefractive Interferometer and a Powerful Long Pulse Laser written by Guy Rousseau and published by . This book was released on 2008 with total page 24 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Evaluation of Harmonic Motion Elastography and Acousto-optic Imaging for Monitoring Lesion Formation by High Intensity Focused Ultrasound by : Andrew Bruce Draudt
Download or read book Evaluation of Harmonic Motion Elastography and Acousto-optic Imaging for Monitoring Lesion Formation by High Intensity Focused Ultrasound written by Andrew Bruce Draudt and published by . This book was released on 2012 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: Abstract: Malignant or benign tumors may be ablated with high-intensity focused ultrasound (HIFU). This technique, known as focused ultrasound surgery (FUS), has been actively investigated for decades, but slow to be implemented and difficult to control due to lack of real-time feedback during ablation. Two methods of imaging and monitoring HIFU lesions during formation were implemented simultaneously, in order to investigate the efficacy of each and to increase confidence in the detection of the lesion. The first, Acousto-Optic Imaging (AOI) detects the increasing optical absorption and scattering in the lesion. The intensity of a diffuse optical field in illuminated tissue is mapped at the spatial resolution of an ultrasound focal spot, using the acousto-optic effect. The second, Harmonic Motion Imaging (HMI), detects the changing stiffness in the lesion. The HIFU beam is modulated to force oscillatory motion in the tissue, and the amplitude of this motion, measured by ultrasound pulse-echo techniques, is influenced by the stiffness. Experiments were performed on store-bought chicken breast and freshly slaughtered bovine liver. The AOI results correlated with the onset and relative size of forming lesions much better than prior knowledge of the HIFU power and duration. For HMI, a significant artifact was discovered due to acoustic nonlinearity. The artifact was mitigated by adjusting the phase of the HIFU and imaging pulses. A more detailed model of the HMI process than previously published was made using finite element analysis. The model showed that the amplitude of harmonic motion was primarily affected by increases in acoustic attenuation and stiffness as the lesion formed and the interaction of these effects was complex and often counteracted each other. Further biological variability in tissue properties meant that changes in motion were masked by sample-to-sample variation. The HMI experiments predicted lesion formation in only about a quarter of the lesions made. In simultaneous AOI/HMI experiments it appeared that AOI was a more robust method for lesion detection.
Book Synopsis Ultrasound Modulated Optical Tomography in Optical Diffuse Medium Using Acoustic Radiation Force by : Rui Li
Download or read book Ultrasound Modulated Optical Tomography in Optical Diffuse Medium Using Acoustic Radiation Force written by Rui Li and published by . This book was released on 2011 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Physical Basis of Acousto-optical Imaging by : Christopher W. Jarrett
Download or read book Physical Basis of Acousto-optical Imaging written by Christopher W. Jarrett and published by . This book was released on 2014 with total page 165 pages. Available in PDF, EPUB and Kindle. Book excerpt:
