Hyaluronic Acid for Biomedical and Pharmaceutical Applications

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Author :
Publisher : Smithers Rapra
ISBN 13 : 1909030783
Total Pages : 238 pages
Book Rating : 4.9/5 (9 download)

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Book Synopsis Hyaluronic Acid for Biomedical and Pharmaceutical Applications by : Maurice N Collins

Download or read book Hyaluronic Acid for Biomedical and Pharmaceutical Applications written by Maurice N Collins and published by Smithers Rapra. This book was released on 2014-10-09 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hyaluronic acid (HA) is found in extracellular tissue in many parts of the body. It is a material of increasing importance to biomaterials science and is finding applications in diverse areas ranging from tissue culture scaffolds to cosmetic materials. Its properties, both physical and biochemical, in solution or hydrogel form, are extremely attractive for various technologies concerned with body repair. This book considers the materials science behind some of the important biomedical and therapeutic applications that are emerging for HA. Key characteristics such as its mechanical properties, biological function and degradation are discussed. The latest technologies in chemical modification and crosslinking strategies are analysed and emerging applications in soft and hard tissue repair are highlighted. The first objective of the book, which consists of a collection of chapters from leading researchers across the globe, is to highlight the role of HA based hydrogels as scaffolds in sustaining stem cells for transplantation and regrowth. The second objective is to detail the significant influence of HA derived materials in the latest advances in cancer therapy, general therapeutics and cosmetics. The third objective is to link the structure-property relationships of HA to medical function and application while reflecting on current clinical and market trends. The book will be of interest to those involved in HA research for medical device and therapeutic applications. Graduate and undergraduate students engaged in the fields of biomedical engineering, materials science, chemistry, medical science, pharmaceutical science and polymer science will find this book of particular interest.

Hyaluronic Acid

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 111869595X
Total Pages : 228 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Hyaluronic Acid by : V. N. Khabarov

Download or read book Hyaluronic Acid written by V. N. Khabarov and published by John Wiley & Sons. This book was released on 2014-12-22 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hyaluronic acid is an essential part of connective, epithelial and neural tissues, and contributes to cell proliferation and migration. It is used as a stimulating agent for collagen synthesis and is a common ingredient in skin-care products, a multi-billion dollar industry, as it is believed to be a key factor in fighting the aging process. Hyaluronic Acid: Production, Properties, Application in Biology and Medicine consists of six chapters discussing the various issues of hyaluronic acid research. In Chapter 1, a historical analysis recounts the discovery and milestones of the research leading to the practical applications of hyaluronan. Chapter 2 is dedicated to biological role of the hyaluronic acid in nature, in particular in the human body. The chapter starts from the phylogenesis of hyaluronic acid, then describes hyaluronan functions in human ontogenesis and especially the role which hyaluronan plays in extracellular matrix of the different tissues. Chapter 3 describes the methods to manufacture and purify hyaluronic acid, including the analytical means for assessing quality of the finished product. Chapter 4 discusses the structure and rheological properties of hyaluronic acid considering effects on conformation and biological properties related to molecular weight. In Chapter 5, the physical and chemical methods for modifying the structure of hyaluronan are discussed including cross-linking using bi-functional reagents, solid-phase modification and effects of the combined action of high pressures and shift deformation. The final chapter focuses on the products derived from hyaluronic acid, including therapeutics composed of modified hyaluronan conjugated to vitamins, amino acids and oligo-peptides. The biological roles and medical applications of this polysaccharide have been extensively studied and this book provides a wealth of scientific data demonstrating the critical role of hyaluronic acid and its promise as a multifaceted bio-macromolecule. Approaching hyaluronic acid from multiple angles, this book links relationships between its biological functions, structure and physical–chemical properties. It will be an invaluable resource to researchers, both industrial and academic, involved in all aspects of hyaluronan-based technologies.

Studies in the Hyaluronidase - Hyaluronic Acid System

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Author :
Publisher :
ISBN 13 :
Total Pages : 20 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Studies in the Hyaluronidase - Hyaluronic Acid System by : Alice L. Mathis

Download or read book Studies in the Hyaluronidase - Hyaluronic Acid System written by Alice L. Mathis and published by . This book was released on 1949 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Practical Aspects of Hyaluronan Based Medical Products

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Author :
Publisher : CRC Press
ISBN 13 : 1420037641
Total Pages : 238 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Practical Aspects of Hyaluronan Based Medical Products by : J.W. Kuo

Download or read book Practical Aspects of Hyaluronan Based Medical Products written by J.W. Kuo and published by CRC Press. This book was released on 2005-09-23 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ballooning body of research devoted to hyaluronan (HA) reflects its enormous potential for various medical applications. There have been many successes of varying degrees in the development of medical products based on HA, but also some setbacks. While there is obviously ample information available on the chemistry and various properties of thi

Studies in the Hyaluronidase - Hyaluronic Acid System

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Author :
Publisher :
ISBN 13 :
Total Pages : 20 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Studies in the Hyaluronidase - Hyaluronic Acid System by : Robert E. Brooks

Download or read book Studies in the Hyaluronidase - Hyaluronic Acid System written by Robert E. Brooks and published by . This book was released on 1949 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Hyaluronan

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Author :
Publisher : Springer Nature
ISBN 13 : 3031303008
Total Pages : 220 pages
Book Rating : 4.0/5 (313 download)

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Book Synopsis Hyaluronan by : Alberto Passi

Download or read book Hyaluronan written by Alberto Passi and published by Springer Nature. This book was released on 2023-06-22 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses the structural and biological properties of the extracellular matrix component and glycosaminoglycan polymer hyaluronan (or hyaluronic acid, HA). The book discusses various aspects of HA biology, e.g., HA synthesis and degradation, as well as the role of HA in embryogenesis, development, and cell maintenance. The reader will learn about the role of HA in different tissues as well as its biological activities triggered by the interaction with different HA receptors. A closer look is had at the involvement of HA in human pathologies such as cancer, kidney fibrosis and wound healing. Biotechnological and biomedical applications for HA such as scaffold generation and drug delivery, including the novel synthetic sulphated HA are explored. This work will appeal to a wide readership within the extracellular matrix and hyaluronan field. It can serve as an introduction to the field for junior scientists but can also help senior scientists to gain a broader view of the field beyond their area of specialization. The series Biology of Extracellular Matrix is published in collaboration with the American Society for Matrix Biology and the International Society for Matrix Biology.

Hyaluronic Acid

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Publisher :
ISBN 13 : 9781536170603
Total Pages : 152 pages
Book Rating : 4.1/5 (76 download)

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Book Synopsis Hyaluronic Acid by : Riia Rautiola

Download or read book Hyaluronic Acid written by Riia Rautiola and published by . This book was released on 2020-02-19 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Hyaluronic acid, or hyaluronan, is a water soluble, anionic extracellular matrix glycosaminoglycan polymer with variable molecular weight that determines its physiological role, rheological properties and applications. Since its discovery in the early 1930s, there has been an increased awareness concerning the biology of hyaluronic acid, its signaling pathways and its role in the biomedical and cosmeceutical industry. Being an endogenous molecule, hyaluronic acid is biocompatible, biodegradable, and has strong mucoadhesive, viscoelastic properties. The authors provide chemical modification approaches to hyaluronic acid, as well as address the magnitude of applications of hyaluronic acid-based targeted drug vectors and patents. The closing study discusses glycosaminoglycans, a specialized group of unbranched, anionic disaccharide polymers attached by a covalent linkage to the membrane proteins via sulphate groups in their sugar moieties"--

The Biology of Hyaluronan

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 0470513780
Total Pages : 308 pages
Book Rating : 4.4/5 (75 download)

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Book Synopsis The Biology of Hyaluronan by : David Evered

Download or read book The Biology of Hyaluronan written by David Evered and published by John Wiley & Sons. This book was released on 2008-04-30 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents state-of-the-art applications in hyaluronan research, from hyaluronan's physicochemical properties to its clinical role as a connective tissue marker and its surgical implications, particularly in ear, eye and orthopaedic surgery. Covers hyaluronan's synthesis and catabolism, its role in cells, its interactions with specific binding proteins, and its role in the embryonic nervous system.

Effect of X-irradiation on the Hyaluronidase-hyaluronic Acid System

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Author :
Publisher :
ISBN 13 :
Total Pages : 20 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Effect of X-irradiation on the Hyaluronidase-hyaluronic Acid System by : Melvin D. Schoenberg

Download or read book Effect of X-irradiation on the Hyaluronidase-hyaluronic Acid System written by Melvin D. Schoenberg and published by . This book was released on 1950 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Chemistry and Biology of Hyaluronan

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Author :
Publisher : Elsevier
ISBN 13 : 0080472222
Total Pages : 625 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Chemistry and Biology of Hyaluronan by : Hari G. Garg

Download or read book Chemistry and Biology of Hyaluronan written by Hari G. Garg and published by Elsevier. This book was released on 2004-07-14 with total page 625 pages. Available in PDF, EPUB and Kindle. Book excerpt: It was probably the French chemist Portes, who first reported in 1880 that the mucin in the vitreous body, which he named hyalomucine, behaved differently from other mucoids in cornea and cartilage. Fifty four years later Karl Meyer isolated a new polysaccharide from the vitreous, which he named hyaluronic acid. Today its official name is hyaluronan, and modern-day research on this polysaccharide continues to grow. Expertly written by leading scientists in the field, this book provides readers with a broad, yet detailed review of the chemistry of hyaluronan, and the role it plays in human biology and pathology. Twenty-seven chapters present a sequence leading from the chemistry and biochemistry of hyaluronan, followed by its role in various pathological conditions, to modified hylauronans as potential therapeutic agents and finally to the functional, structural and biological properties of hyaluronidases. Chemistry and Biology of Hyaluronan covers the many interesting facets of this fascinating molecule, and all chapters are intended to reach the wider research community. Comprehensive look at the chemistry and biology of hyaluronans Essential to Chemists, Biochemists and Medical researchers Broad yet detailed review of this rapidly growing research area

The Hyaluronic Acid Miracle

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Publisher :
ISBN 13 : 9781893910690
Total Pages : 0 pages
Book Rating : 4.9/5 (16 download)

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Book Synopsis The Hyaluronic Acid Miracle by : Chris D. Meletis

Download or read book The Hyaluronic Acid Miracle written by Chris D. Meletis and published by . This book was released on 2010-09 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: A complete guide to the world's most exciting anti-aging compound for flexible joints, vibrant skin and a healthy heart. Now, for the first time, the anti-aging secrets of hyaluronic acid are revealed by two of the leading experts. Learn how hyaluronic acid can: *Give anyone an instant facelift *Replace a Botox injection *Offer full, plump lips and skin *Thicken your hair *Improve your vision and eliminate floaters *Provide the cushioning fluid your joints need to move freely *Improve your heart and circulatory health

Hyaluronan Signaling and Turnover

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Publisher : Academic Press
ISBN 13 : 0128003936
Total Pages : 418 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Hyaluronan Signaling and Turnover by : Melanie Simpson

Download or read book Hyaluronan Signaling and Turnover written by Melanie Simpson and published by Academic Press. This book was released on 2014-07-26 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. Here, once again, outstanding and original reviews are presented on a variety of topics. This volume covers hyaluronan signaling and turnover. Provides information on cancer research Outstanding and original reviews Suitable for researchers and students

Hyaluronan in Cancer Biology

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Publisher : Academic Press
ISBN 13 : 0080921086
Total Pages : 467 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Hyaluronan in Cancer Biology by : Robert Stern

Download or read book Hyaluronan in Cancer Biology written by Robert Stern and published by Academic Press. This book was released on 2009-03-07 with total page 467 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hyaluronan biology is being recognized as an important regulator of cancer progression. Paradoxically, both hyaluronan (HA) and hyaluronidases, the enzymes that eliminate HA, have also been correlated with cancer progression. Hyaluronan, a long-chain polymer of the extracellular matrix, opens up tissue spaces through which cancer cells move and metastasize. It also confers motility upon cells through interactions of cell-surface HA with the cytoskeleton. Embryonic cells in the process of movement and proliferation use the same strategy. It is an example of how cancer cells have commandeered normal cellular processes for their own survival and spread. There are also parallels between cancer and wound healing, cancer occasionally being defined as a wound that does not heal. The growing body of literature regarding this topic has recently progressed from describing the association of hyaluronan and hyaluronidase expression associated with different cancers, to understanding the mechanisms that drive tumor cell activation, proliferation, drug resistance, etc. No one source, however, discusses hyaluronan synthesis and catabolism, as well as the factors that regulate the balance. This book will offer a comprehensive summary and cutting-edge insight into Hyaluronan biology, the role of the HA receptors, the hyaluronidase enzymes that degrade HA, as well as HA synthesis enzymes and their relationship to cancer. Offers a comprehensive summary and cutting-edge insight into Hyaluronan biology, the role of the HA receptors, the hyaluronidase enzymes that degrade HA, as well as HA synthesis enzymes and their relationship to cancer Chapters are written by the leading international authorities on this subject, from laboratories that focus on the investigation of hyaluronan in cancer initiation, progression, and dissemination Focuses on understanding the mechanisms that drive tumor cell activation, proliferation, and drug resistance

Hyaluronic Acid in Ophthalmology

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Publisher :
ISBN 13 : 9783940667137
Total Pages : 48 pages
Book Rating : 4.6/5 (671 download)

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Book Synopsis Hyaluronic Acid in Ophthalmology by : Helmut Rudolf Höh

Download or read book Hyaluronic Acid in Ophthalmology written by Helmut Rudolf Höh and published by . This book was released on 2005 with total page 48 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Chemistry, Biology and Medical Applications of Hyaluronan and Its Derivatives

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Author :
Publisher : Portland Press, London
ISBN 13 :
Total Pages : 368 pages
Book Rating : 4.E/5 ( download)

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Book Synopsis The Chemistry, Biology and Medical Applications of Hyaluronan and Its Derivatives by : T. C. Laurent

Download or read book The Chemistry, Biology and Medical Applications of Hyaluronan and Its Derivatives written by T. C. Laurent and published by Portland Press, London. This book was released on 1998 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of this book is to collect within one volume information on hyaluronan. This polysaccharide has received rapid attention for two reasons: it has important regulative functions within cell biology; and it has become a commercially important product because of its use in ophthalmic surgery and treatment of joint diease. A number of other practical applications are also discussed. The book covers various aspects of hyaluronan from the structure and chemistry of the polymer to its metabolism, cell biological interactions, behaviour in pathological processes, and potentially new medical applications.

Safe Filler Injection Techniques

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Publisher : Springer Nature
ISBN 13 : 9811668558
Total Pages : 80 pages
Book Rating : 4.8/5 (116 download)

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Book Synopsis Safe Filler Injection Techniques by : Won Lee

Download or read book Safe Filler Injection Techniques written by Won Lee and published by Springer Nature. This book was released on 2021-11-18 with total page 80 pages. Available in PDF, EPUB and Kindle. Book excerpt: Filler injection is one of the most common aesthetic procedure. There are a lot of guidelines but there are no illustrated step by step instructions on safe filler injection procedures. The book will offer guidance to clinicians who wish to expand their practice to minimally invasive cosmetic procedures. Injection techniques for hyaluronic acid filler is highlighted to help practitioners perform the procedures more effectively and safely with evidence based approach. The most safe procedure including vascular anatomical illustration and ultrasound findings, rheological data is presented.

Hyaluronan

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Publisher :
ISBN 13 : 9781631178122
Total Pages : 178 pages
Book Rating : 4.1/5 (781 download)

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Book Synopsis Hyaluronan by : Vitor H. Pomin

Download or read book Hyaluronan written by Vitor H. Pomin and published by . This book was released on 2014-05-21 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hyaluronan or hyaluronic acid (HA), the only non-sulfated glycosaminoglycan (GAG) of the body, is structurally composed of disaccharide repeating units of alternating 3-linked N-acetyl ?-D-glucosamine and 4-linked ?-D-glucuronic acid. Despite the lack of sulfation and the lowest structural heterogeneity among all GAGs, HA still retains efficient capability in interacting with many molecules, especially functional proteins like growth factors, cytokines, and adhesive proteins involved in angiogenesis, tumor proliferation, migration and invasion. However, the main biological role of HA is to assemble the extracellular matrices of certain soft tissues, such as vitreous humor, synovial fluid, umbilical cord and the intercellular space of the epidermis. HA is the major structure-forming component in the globe of the eye and cornea. For this reason, this GAG can be used to compose ophthalmic solutions. The most famous physicochemical property of HA is its capacity to make gels in solution. This property can be pharmaceutically and industrially useful as either a vehicle to make specific media or biologically active sera. This book, heavily based on recent scientific results from research groups of several countries, will cover many of these aspects of HA, the related enzymes and metabolism in health and disease. The seven chapters are basically centered in 1) the covalent modifications of HA by serum protein and the biological consequences; 2) the aspects of HA as a function of age; 3) carcinogenesis as a function of HA metabolism; 4) therapeutic applications of HA-related enzymes; 5) characterization and analyses of HA-based ophthalmic solutions; 6) the role of HA in reproductive medicine; and 7) the role of HA in bone medicine. The contributing authors are renowned scientists in the HA field and this collaborates to the high-quality of this publication.