Accessing Uncultivated Microorganisms

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Publisher :
ISBN 13 : 9781555814069
Total Pages : 332 pages
Book Rating : 4.8/5 (14 download)

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Book Synopsis Accessing Uncultivated Microorganisms by : Karsten Zengler

Download or read book Accessing Uncultivated Microorganisms written by Karsten Zengler and published by . This book was released on 2008 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing a comprehensive overview and discussing developments in the field, this book details various innovative methods used in microbial ecology and environmental microbiology. It also includes all aspects of microbial diversity from bacteria and fungi to protists.

Uncharted Microbial World

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ISBN 13 :
Total Pages : 41 pages
Book Rating : 4.:/5 (727 download)

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Book Synopsis Uncharted Microbial World by :

Download or read book Uncharted Microbial World written by and published by . This book was released on 2007 with total page 41 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbes are the foundation for all of life. From the air we breathe to the soil we rely on for farming to the water we drink, everything humans need to survive is intimately coupled with the activities of microbes. Major advances have been made in the understanding of disease and the use of microorganisms in the industrial production of drugs, food products and wastewater treatment. However, our understanding of many complicated microbial environments (the gut and teeth), soil fertility, and biogeochemical cycles of the elements is lagging behind due to their enormous complexity. Inadequate technology and limited resources have stymied many lines of investigation. Today, most environmental microorganisms have yet to be isolated and identified, let alone rigorously studied. The American Academy of Microbiology convened a colloquium in Seattle, Washington, in February 2007, to deliberate the way forward in the study of microorganisms and microbial activities in the environment. Researchers in microbiology, marine science, pathobiology, evolutionary biology, medicine, engineering, and other fields discussed ways to build on and extend recent successes in microbiology. The participants made specific recommendations for targeting future research, improving methodologies and techniques, and enhancing training and collaboration in the field. Microbiology has made a great deal of progress in the past 100 years, and the useful applications for these new discoveries are numerous. Microorganisms and microbial products are now used in industrial capacities ranging from bioremediation of toxic chemicals to probiotic therapies for humans and livestock. On the medical front, studies of microbial communities have revealed, among other things, new ways for controlling human pathogens. The immediate future for research in this field is extremely promising. In order to optimize the effectiveness of community research efforts in the future, scientists should include manageable systems with features like clear physical boundaries, limited microbial diversity, and manipulability with the goal of understanding fundamental principles that may apply to more complex systems. A great deal of microbial genetic and phenotypic diversity remains to be explored, and the commercial and medical potential locked up in these unknowns should compel the field to move forward. Future microbiology research will build on the successes of the past using new techniques and approaches. Uncultivated microbes hold great promise for industry, medicine, and the recycling of precious resources, and research and technology must make inroads in overcoming the barriers that prevent their study. In many cases, we will no longer be able to rely on isolated, pure cultures of microorganisms, but must use communities of microorganisms, which presently are poorly understood. Indeed, community-level studies can benefit from deconstructing microbial communities and analyzing the component members separately, but this is not feasible in every system. The effects of perturbation on microbial communities also require study. Humans rely on the services of microbes in innumerable ways, but we have little or no predictive understanding of how microbial communities respond to disturbance. Research must address current limitations in detecting microscale interactions among microbes by enhancing current technologies and fostering new microscopic tools, biosensors, and gas sensors for appropriate small scales. Genomics, which has enabled great progress in microbiology research of individual species, must be applied to communities of microorganisms. This will require improved methods of DNA extraction and amplification from environmental samples and improved strategies for DNA sequence assembly. In the future, genome sequencing efforts should continue the exploration of evolutionarily diverse microbes, as well as help reveal the mechanisms by which closely related microbes evolve. Technological advances have spurred every great leap in microbial biology, and in order to move forward, new methods for revealing the activities of microorganisms must be continually developed. Today, researchers need access to better techniques for enriching and isolating novel microorganisms, particularly approaches that enable them to mimic the low nutrient conditions to which many environmental microbes are adapted. Other outstanding needs include methods for performing in situ work and bioinformatics tools. Finally, there are several ways that training and education in microbiology are failing to adequately prepare the next generation of scientists for the challenges ahead. Training in some of the long-established disciplines, including enrichment and isolation, physiology, enzymology, and biochemistry, needs to be revitalized.

Uncultivated Microorganisms

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Publisher : Springer Science & Business Media
ISBN 13 : 3540854657
Total Pages : 215 pages
Book Rating : 4.5/5 (48 download)

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Book Synopsis Uncultivated Microorganisms by : Slava S. Epstein

Download or read book Uncultivated Microorganisms written by Slava S. Epstein and published by Springer Science & Business Media. This book was released on 2009-09-01 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1898, an Austrian microbiologist Heinrich Winterberg made a curious observation: the number of microbial cells in his samples did not match the number of colonies formed on nutrient media (Winterberg 1898). About a decade later, J. Amann qu- tified this mismatch, which turned out to be surprisingly large, with non-growing cells outnumbering the cultivable ones almost 150 times (Amann 1911). These papers signify some of the earliest steps towards the discovery of an important phenomenon known today as the Great Plate Count Anomaly (Staley and Konopka 1985). Note how early in the history of microbiology these steps were taken. Detecting the Anomaly almost certainly required the Plate. If so, then the period from 1881 to 1887, the years when Robert Koch and Petri introduced their key inventions (Koch 1881; Petri 1887), sets the earliest boundary for the discovery, which is remarkably close to the 1898 observations by H. Winterberg. Celebrating its 111th anniversary, the Great Plate Count Anomaly today is arguably the oldest unresolved microbiological phenomenon. In the years to follow, the Anomaly was repeatedly confirmed by all microb- logists who cared to compare the cell count in the inoculum to the colony count in the Petri dish (cf., Cholodny 1929; Butkevich 1932; Butkevich and Butkevich 1936). By mid-century, the remarkable difference between the two counts became a universally recognized phenomenon, acknowledged by several classics of the time (Waksman and Hotchkiss 1937; ZoBell 1946; Jannasch and Jones 1959).

Microbes in Land Use Change Management

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Publisher : Elsevier
ISBN 13 : 0323858945
Total Pages : 611 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis Microbes in Land Use Change Management by : Jay Shankar Singh

Download or read book Microbes in Land Use Change Management written by Jay Shankar Singh and published by Elsevier. This book was released on 2021-08-20 with total page 611 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbes in Land Use Change Management details the various roles of microbial resources in management of land uses and how the microbes can be used for the source of income due to their cultivation for the purpose of biomass and bioenergy production. Using various techniques, the disturbed and marginal lands may also be restored eco-friendly in present era to fulfil the feeding needs of mankind around the globe. Microbes in Land Use Change Management provides standard and up to date information towards the land use change management using various microbial technologies to enhance the productivity of agriculture. Needless to say that Microbes in Land Use Change Management also considers the areas including generation of alternative energy sources, restoration of degraded and marginal lands, mitigation of global warming gases and next generation -omics technique etc. Land use change affects environment conditions and soil microbial community. Microbial population and its species diversity have influence in maintaining ecosystem balance. The study of changes of microbial population provides an idea about the variation occurring in a specific area and possibilities of restoration. Meant for a multidisciplinary audience Microbes in Land Use Change Management shows the need of next-generation omics technologies to explore microbial diversity. Describes the role of microbes in generation of alternative source of energy Gives recent information related to various microbial technology and their diversified applications Provides thorough insight in the problems related to landscape dynamics, restoration of soil, reclamation of lands mitigation of global warming gases etc. eco-friendly way using versatility of microbes Includes microbial tools and technology in reclamation of degraded, disturbed and marginal lands, mitigation of global warming gases

Psychrophiles: From Biodiversity to Biotechnology

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Publisher : Springer
ISBN 13 : 3319570579
Total Pages : 685 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Psychrophiles: From Biodiversity to Biotechnology by : Rosa Margesin

Download or read book Psychrophiles: From Biodiversity to Biotechnology written by Rosa Margesin and published by Springer. This book was released on 2017-06-22 with total page 685 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cold adaptation includes a complex range of structural and functional adaptations at the level of all cellular constituents, and these adaptations render cold-adapted organisms particularly useful for biotechnological applications. This book presents the most recent knowledge of (i) boundary conditions for microbial life in the cold, (ii) microbial diversity in various cold ecosystems, (iii) molecular cold adaptation mechanisms and (iv) the resulting biotechnological perspectives.

Microbial Evolution and Co-Adaptation

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Publisher : National Academies Press
ISBN 13 : 0309131219
Total Pages : 330 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Microbial Evolution and Co-Adaptation by : Institute of Medicine

Download or read book Microbial Evolution and Co-Adaptation written by Institute of Medicine and published by National Academies Press. This book was released on 2009-05-10 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr. Joshua Lederberg - scientist, Nobel laureate, visionary thinker, and friend of the Forum on Microbial Threats - died on February 2, 2008. It was in his honor that the Institute of Medicine's Forum on Microbial Threats convened a public workshop on May 20-21, 2008, to examine Dr. Lederberg's scientific and policy contributions to the marketplace of ideas in the life sciences, medicine, and public policy. The resulting workshop summary, Microbial Evolution and Co-Adaptation, demonstrates the extent to which conceptual and technological developments have, within a few short years, advanced our collective understanding of the microbiome, microbial genetics, microbial communities, and microbe-host-environment interactions.

The Social Biology of Microbial Communities

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Publisher : National Academies Press
ISBN 13 : 0309264324
Total Pages : 633 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis The Social Biology of Microbial Communities by : Institute of Medicine

Download or read book The Social Biology of Microbial Communities written by Institute of Medicine and published by National Academies Press. This book was released on 2013-01-10 with total page 633 pages. Available in PDF, EPUB and Kindle. Book excerpt: Beginning with the germ theory of disease in the 19th century and extending through most of the 20th century, microbes were believed to live their lives as solitary, unicellular, disease-causing organisms . This perception stemmed from the focus of most investigators on organisms that could be grown in the laboratory as cellular monocultures, often dispersed in liquid, and under ambient conditions of temperature, lighting, and humidity. Most such inquiries were designed to identify microbial pathogens by satisfying Koch's postulates.3 This pathogen-centric approach to the study of microorganisms produced a metaphorical "war" against these microbial invaders waged with antibiotic therapies, while simultaneously obscuring the dynamic relationships that exist among and between host organisms and their associated microorganisms-only a tiny fraction of which act as pathogens. Despite their obvious importance, very little is actually known about the processes and factors that influence the assembly, function, and stability of microbial communities. Gaining this knowledge will require a seismic shift away from the study of individual microbes in isolation to inquiries into the nature of diverse and often complex microbial communities, the forces that shape them, and their relationships with other communities and organisms, including their multicellular hosts. On March 6 and 7, 2012, the Institute of Medicine's (IOM's) Forum on Microbial Threats hosted a public workshop to explore the emerging science of the "social biology" of microbial communities. Workshop presentations and discussions embraced a wide spectrum of topics, experimental systems, and theoretical perspectives representative of the current, multifaceted exploration of the microbial frontier. Participants discussed ecological, evolutionary, and genetic factors contributing to the assembly, function, and stability of microbial communities; how microbial communities adapt and respond to environmental stimuli; theoretical and experimental approaches to advance this nascent field; and potential applications of knowledge gained from the study of microbial communities for the improvement of human, animal, plant, and ecosystem health and toward a deeper understanding of microbial diversity and evolution. The Social Biology of Microbial Communities: Workshop Summary further explains the happenings of the workshop.

Science Needs for Microbial Forensics

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ISBN 13 : 9780309302456
Total Pages : 0 pages
Book Rating : 4.3/5 (24 download)

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Book Synopsis Science Needs for Microbial Forensics by : National Research Council (U.S.). Committee on Science Needs for Microbial Forensics: Developing an Initial International Roadmap

Download or read book Science Needs for Microbial Forensics written by National Research Council (U.S.). Committee on Science Needs for Microbial Forensics: Developing an Initial International Roadmap and published by . This book was released on 2014 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: For these reasons, building awareness of and capacity in microbial forensics can assist in our understanding of what may have occurred during a biothreat event, and international collaborations that engage the broader scientific and policy-making communities are likely to strengthen our microbial forensics capabilities. One goal would be to create a shared technical understanding of the possibilities--and limitations--of the scientific bases for microbial forensics analysis. Science Needs for Microbial Forensics: Developing Initial International Research Priorities, based partly on a workshop held in Zabgreb, Croatia in 2013, identifies scientific needs that must be addressed to improve the capabilities of microbial forensics to investigate infectious disease outbreaks and provide evidence of sufficient quality to support legal proceedings and the development of government policies.

Nonculturable Microorganisms in the Environment

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Publisher : Springer Science & Business Media
ISBN 13 : 147570271X
Total Pages : 355 pages
Book Rating : 4.4/5 (757 download)

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Book Synopsis Nonculturable Microorganisms in the Environment by : Colwell

Download or read book Nonculturable Microorganisms in the Environment written by Colwell and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text on viable but non-culturable organisms provides information on topics including: morphological changes; the role of membranes; genetics and genetic regulation; molecular methods for detection; as well as survival dominancy and related phenomena. The main purpose of the text is to elucidate the phenomenon and to distinguish it from other seemingly related but different phenomena such as spore formation, dormancy, starvation, and injury. It covers a cross section of morphology, metabolism, genetics, ecology and epidemiology.

Using the Biological Literature

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Publisher : CRC Press
ISBN 13 : 146655858X
Total Pages : 362 pages
Book Rating : 4.4/5 (665 download)

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Book Synopsis Using the Biological Literature by : Diane Schmidt

Download or read book Using the Biological Literature written by Diane Schmidt and published by CRC Press. This book was released on 2014-04-14 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: The biological sciences cover a broad array of literature types, from younger fields like molecular biology with its reliance on recent journal articles, genomic databases, and protocol manuals to classic fields such as taxonomy with its scattered literature found in monographs and journals from the past three centuries. Using the Biological Litera

Biogeography of Microscopic Organisms

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Publisher : Cambridge University Press
ISBN 13 : 1139496581
Total Pages : 387 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis Biogeography of Microscopic Organisms by : Diego Fontaneto

Download or read book Biogeography of Microscopic Organisms written by Diego Fontaneto and published by Cambridge University Press. This book was released on 2011-05-19 with total page 387 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bringing together the viewpoints of leading experts in taxonomy, ecology and biogeography of different taxa, this book synthesises discussion surrounding the so-called 'everything is everywhere' hypothesis. It addresses the processes that generate spatial patterns of diversity and biogeography in organisms that can potentially be cosmopolitan. The contributors discuss questions such as: are microorganisms (e.g. prokaryotes, protists, algae, yeast and microscopic fungi, plants and animals) really cosmopolitan in their distribution? What are the biological properties that allow such potential distribution? Are there processes that would limit their distribution? Are microorganisms intrinsically different from macroscopic ones? What can microorganisms tell us about the generalities of biogeography? Can they be used for experimental biogeography? Written for graduate students and academic researchers, the book promotes a more complete understanding of the spatial patterns and the general processes in biogeography.

Handbook of Aquatic Microbiology

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Publisher : CRC Press
ISBN 13 : 104010195X
Total Pages : 375 pages
Book Rating : 4.0/5 (41 download)

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Book Synopsis Handbook of Aquatic Microbiology by : Pramod Kumar Pandey

Download or read book Handbook of Aquatic Microbiology written by Pramod Kumar Pandey and published by CRC Press. This book was released on 2024-09-26 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: Short Blurb This handbook covers the different aspects of the aquatic environment, microbiology, and microbial applications. It highlights the role of microorganisms as pollution indicators and as bio-control agents. The book covers the impact of pollution on microorganisms, biofilms, cyanobacterial blooms, and the metagenomics approach to isolate microbes. Standard Blurb This comprehensive handbook covers the different aspects of the aquatic environment, microbiology, and microbial applications. The world’s aquatic environment is facing a serious threat due to inappropriate planning, implementation, and management. This book compiles effective strategies for managing the aquatic environment. It highlights the role of microorganisms as pollution indicators, in bioremediation, and as bio-control agents. The book also covers the impact of pollution on microorganisms, biofilms, cyanobacterial blooms, and the metagenomics approach to isolate microbes. This book is essential for students and researchers of microbiology, environmental sciences, and biotechnology Seasonal Blurb This comprehensive handbook covers the different aspects of the aquatic environment, microbiology, and microbial applications. The world’s aquatic environment is facing a serious threat due to inappropriate planning, implementation, and management. This book compiles effective strategies for managing the aquatic environment. It highlights the role of microorganisms as pollution indicators, in bioremediation, and as bio-control agents. The book also covers the impact of pollution on microorganisms, biofilms, cyanobacterial blooms, and the metagenomics approach to isolate microbes. This book is essential for students and researchers of Microbiology, Environmental Sciences, and Biotechnology. 1 Includes key themes like environmental DNA application, metagenomes, extremophiles, microbial population genetics and statistical aspects of aquatic microbiology 2 Discusses the beneficial microbes of the aquatic environment 3 Covers applications of microbes in bioremediation, as pollution indicators and as algicidal agents 4 Reviews freshwater biogeochemical cycles and sediment microbiology 5 Explores microbial communities of biofloc and microbiomes in aquaponics

Microbial Ecology of Wastewater Treatment Plants

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Publisher : Elsevier
ISBN 13 : 0128225041
Total Pages : 572 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Microbial Ecology of Wastewater Treatment Plants by : Maulin P Shah

Download or read book Microbial Ecology of Wastewater Treatment Plants written by Maulin P Shah and published by Elsevier. This book was released on 2021-05-15 with total page 572 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbial Ecology of Wastewater Treatment Plants presents different methods and techniques used in microbial ecology to study the interactions and evolution of microbial populations in WWTPs, particularly the new molecular tools developed in the last decades. These molecular biology-based methods (e.g. studies of DNA, RNA and proteins) provide a high resolution of information compared to traditional ways of studying microbial wastewater populations, such as microscopic examination and culture-based methods. In addition, this book addresses the ability of microorganisms to degrade environmental pollutants. Describes application of different Omics tools in Wastewater treatment plants (WWTPs) Demonstrates the role of microorganisms in WWTPs Includes discussions on the microbial ecology of WWTPs Covers the microbial diversity of activated sludge Emphasizes cutting-edge molecular tools

Encyclopedia of Microbiology

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Publisher : Academic Press
ISBN 13 : 0128117370
Total Pages : 3248 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Encyclopedia of Microbiology by : Thomas M. Schmidt

Download or read book Encyclopedia of Microbiology written by Thomas M. Schmidt and published by Academic Press. This book was released on 2019-09-11 with total page 3248 pages. Available in PDF, EPUB and Kindle. Book excerpt: Encyclopedia of Microbiology, Fourth Edition, Five Volume Set gathers both basic and applied dimensions in this dynamic field that includes virtually all environments on Earth. This range attracts a growing number of cross-disciplinary studies, which the encyclopedia makes available to readers from diverse educational backgrounds. The new edition builds on the solid foundation established in earlier versions, adding new material that reflects recent advances in the field. New focus areas include `Animal and Plant Microbiomes’ and ‘Global Impact of Microbes`. The thematic organization of the work allows users to focus on specific areas, e.g., for didactical purposes, while also browsing for topics in different areas. Offers an up-to-date and authoritative resource that covers the entire field of microbiology, from basic principles, to applied technologies Provides an organic overview that is useful to academic teachers and scientists from different backgrounds Includes chapters that are enriched with figures and graphs, and that can be easily consulted in isolation to find fundamental definitions and concepts

The New Microbiology

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Publisher : John Wiley & Sons
ISBN 13 : 1683670116
Total Pages : 200 pages
Book Rating : 4.6/5 (836 download)

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Book Synopsis The New Microbiology by : Pascale Cossart

Download or read book The New Microbiology written by Pascale Cossart and published by John Wiley & Sons. This book was released on 2020-07-10 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbiology has undergone radical changes over the past few decades, ushering in an exciting new era in science. In The New Microbiology, Pascale Cossart tells a splendid story about the revolution in microbiology, especially in bacteriology. This story has wide-ranging implications for human health and medicine, agriculture, environmental science, and our understanding of evolution. The revolution results from the powerful tools of molecular and cellular biology, genomics, and bioinformatics, which have yielded amazing discoveries, from entire genome sequences to video of bacteria invading host cells. This book is for both scientists and especially nonscientists who would like to learn more about the extraordinary world of bacteria. Dr. Cossart's overview of the field of microbiology research, from infectious disease history to the ongoing scientific revolution resulting from CRISPR technologies, is presented in four parts. New concepts in microbiology introduces the world of bacteria and some recent discoveries about how they live, such as the role of regulatory RNAs including riboswitches, the CRISPR defense system, and resistance to antibiotics. Sociomicrobiology: the social lives of bacteria helps us see the new paradigm by which scientists view bacteria as highly social creatures that communicate in many ways, for example in the assemblies that reside in our intestine or in the environment. The biology of infections reviews some of history's worst epidemics and describes current and emerging infectious diseases, the organisms that cause them, and how they produce an infection. Bacteria as tools introduces us to molecules derived from microbes that scientists have harnessed in the service of research and medicine, including the CRISPR/Cas9 genome-editing technology. The New Microbiology takes us on a journey through a remarkable revolution in science that is occurring here and now.

Metagenomics for Microbiology

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Publisher : Academic Press
ISBN 13 : 0124105084
Total Pages : 188 pages
Book Rating : 4.1/5 (241 download)

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Book Synopsis Metagenomics for Microbiology by : Jacques Izard

Download or read book Metagenomics for Microbiology written by Jacques Izard and published by Academic Press. This book was released on 2014-11-07 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: Concisely discussing the application of high throughput analysis to move forward our understanding of microbial principles, Metagenomics for Microbiology provides a solid base for the design and analysis of omics studies for the characterization of microbial consortia. The intended audience includes clinical and environmental microbiologists, molecular biologists, infectious disease experts, statisticians, biostatisticians, and public health scientists. This book focuses on the technological underpinnings of metagenomic approaches and their conceptual and practical applications. With the next-generation genomic sequencing revolution increasingly permitting researchers to decipher the coding information of the microbes living with us, we now have a unique capacity to compare multiple sites within individuals and at higher resolution and greater throughput than hitherto possible. The recent articulation of this paradigm points to unique possibilities for investigation of our dynamic relationship with these cellular communities, and excitingly the probing of their therapeutic potential in disease prevention or treatment of the future. Expertly describes the latest metagenomic methodologies and best-practices, from sample collection to data analysis for taxonomic, whole shotgun metagenomic, and metatranscriptomic studies Includes clear-headed pointers and quick starts to direct research efforts and increase study efficacy, eschewing ponderous prose Presented topics include sample collection and preparation, data generation and quality control, third generation sequencing, advances in computational analyses of shotgun metagenomic sequence data, taxonomic profiling of shotgun data, hypothesis testing, and mathematical and computational analysis of longitudinal data and time series. Past-examples and prospects are provided to contextualize the applications.

Extremophilic Microbes and Metabolites

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Publisher : BoD – Books on Demand
ISBN 13 : 1839690380
Total Pages : 154 pages
Book Rating : 4.8/5 (396 download)

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Book Synopsis Extremophilic Microbes and Metabolites by : Afef Najjari

Download or read book Extremophilic Microbes and Metabolites written by Afef Najjari and published by BoD – Books on Demand. This book was released on 2021-02-24 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on the diversity and biotechnological applications of metabolites produced by extremophilic microbes thriving in different ecological niches citing the low troposphere, the gastrointestinal tract of ruminants, tropical dry forest, and saline ecosystems. These studies were based on metabolomics and molecular approaches like metagenomics and single-cell genomic analyses. Various implications of Electro-Rheological Fluid are also discussed. The editor embarked on this writing project entitled “Extremophilic Microbes and Metabolites - Diversity, Bioprospecting, and Biotechnological Applications” to make pertinent contributions accessible to the scientific community. Hopefully, a large audience will benefit from the chapters of this book.