Access to Experimental Drugs in Terminal Illness

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Author :
Publisher : CRC Press
ISBN 13 :
Total Pages : 254 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Access to Experimental Drugs in Terminal Illness by : Udo Schüklenk

Download or read book Access to Experimental Drugs in Terminal Illness written by Udo Schüklenk and published by CRC Press. This book was released on 1998-08-21 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this extension of his doctoral research, Schuklenk (U. of Central Lancashire Centre for Professional Ethics; Preston, UK) addresses concerns shared with AIDS activists. He weighs the relevance of Kantian moral philosophy, weak and strong paternalistic arguments regarding access to experimental drugs by the terminally ill, whether access should be restricted to promote clinical trials, the role of the US Food and Drug Administration, costs, and other practical problems; and advocates for global improvement in the drug approval process. Annotation copyrighted by Book News, Inc., Portland, OR

Her-2

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Publisher : Random House
ISBN 13 : 0307764982
Total Pages : 241 pages
Book Rating : 4.3/5 (77 download)

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Book Synopsis Her-2 by : Robert Bazell

Download or read book Her-2 written by Robert Bazell and published by Random House. This book was released on 2011-04-27 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: Two years after she underwent a mastectomy and chemotherapy, Barbara Bradfield's aggressive breast cancer had recurred and spread to her lungs. The outlook was grim. Then she took part in Genentech's clinical trials for a new drug. Five years later she remains cancer-free. Her-2 is the biography of Herceptin, the drug that provoked dramatic responses in Barbara Bradfield and other women in the trials and that offers promise for hundreds of thousands of breast cancer patients. Unlike chemotherapy or radiation, Herceptin has no disabling side effects. It works by inactivating Her-2/neu--a protein that makes cancer cells grow especially quickly-- produced by a gene found in 25 to 30 percent of all breast tumors. Herceptin caused some patients' cancers to disappear completely; in others, it slowed the progression of the disease and gave the women months or years they wouldn't otherwise have had. Herceptin is the first treatment targeted at a gene defect that gives rise to cancer. It marks the beginning of a new era of treatment for all kinds of cancers. Robert Bazell presents a riveting account of how Herceptin was born. Her-2 is a story of dramatic discoveries and strong personalities, showing the combination of scientific investigation, money, politics, ego, corporate decisions, patient activism, and luck involved in moving this groundbreaking drug from the lab to a patient's bedside. Bazell's deft portraits introduce us to the remarkable people instrumental in Herceptin's history, including Dr. Dennis Slamon, the driven UCLA oncologist who played the primary role in developing the treatment; Lily Tartikoff, wife of television executive Brandon Tartikoff, who tapped into Hollywood money and glamour to help fund Slamon's research; and Marti Nelson, who inspired the activists who lobbied for a "compassionate use" program that would allow women outside the clinical trials to have access to the limited supplies of Herceptin prior to FDA approval of the drug. And throughout there are the stories of the heroic women with advanced breast cancer who volunteered for the trials, risking what time they had left on an unproven treatment. Meticulously researched, written with clarity and compassion, Her-2 is masterly reporting on cutting-edge science.

Compassionate Use of Investigational New Drugs

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Publisher :
ISBN 13 :
Total Pages : 168 pages
Book Rating : 4.0/5 (9 download)

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Book Synopsis Compassionate Use of Investigational New Drugs by : United States. Congress. House. Committee on Government Reform

Download or read book Compassionate Use of Investigational New Drugs written by United States. Congress. House. Committee on Government Reform and published by . This book was released on 2001 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt:

A National Cancer Clinical Trials System for the 21st Century

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Author :
Publisher : National Academies Press
ISBN 13 : 0309157870
Total Pages : 317 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis A National Cancer Clinical Trials System for the 21st Century by : Institute of Medicine

Download or read book A National Cancer Clinical Trials System for the 21st Century written by Institute of Medicine and published by National Academies Press. This book was released on 2010-07-08 with total page 317 pages. Available in PDF, EPUB and Kindle. Book excerpt: The National Cancer Institute's (NCI) Clinical Trials Cooperative Group Program has played a key role in developing new and improved cancer therapies. However, the program is falling short of its potential, and the IOM recommends changes that aim to transform the Cooperative Group Program into a dynamic system that efficiently responds to emerging scientific knowledge; involves broad cooperation of stakeholders; and leverages evolving technologies to provide high-quality, practice-changing research.

Physician-Assisted Death

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Publisher : Springer Science & Business Media
ISBN 13 : 1592594484
Total Pages : 159 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Physician-Assisted Death by : James M. Humber

Download or read book Physician-Assisted Death written by James M. Humber and published by Springer Science & Business Media. This book was released on 1994-02-04 with total page 159 pages. Available in PDF, EPUB and Kindle. Book excerpt: Physician-Assisted Death is the eleventh volume of Biomedical Ethics Reviews. We, the editors, are pleased with the response to the series over the years and, as a result, are happy to continue into a second decade with the same general purpose and zeal. As in the past, contributors to projected volumes have been asked to summarize the nature of the literature, the prevailing attitudes and arguments, and then to advance the discussion in some way by staking out and arguing forcefully for some basic position on the topic targeted for discussion. For the present volume on Physician-Assisted Death, we felt it wise to enlist the services of a guest editor, Dr. Gregg A. Kasting, a practicing physician with extensive clinical knowledge of the various problems and issues encountered in discussing physician assisted death. Dr. Kasting is also our student and just completing a graduate degree in philosophy with a specialty in biomedical ethics here at Georgia State University. Apart from a keen interest in the topic, Dr. Kasting has published good work in the area and has, in our opinion, done an excellent job in taking on the lion's share of editing this well-balanced and probing set of essays. We hope you will agree that this volume significantly advances the level of discussion on physician-assisted euthanasia. Incidentally, we wish to note that the essays in this volume were all finished and committed to press by January 1993.

Approaching Death

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Publisher : National Academies Press
ISBN 13 : 0309518253
Total Pages : 457 pages
Book Rating : 4.3/5 (95 download)

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Book Synopsis Approaching Death by : Committee on Care at the End of Life

Download or read book Approaching Death written by Committee on Care at the End of Life and published by National Academies Press. This book was released on 1997-10-30 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: When the end of life makes its inevitable appearance, people should be able to expect reliable, humane, and effective caregiving. Yet too many dying people suffer unnecessarily. While an "overtreated" dying is feared, untreated pain or emotional abandonment are equally frightening. Approaching Death reflects a wide-ranging effort to understand what we know about care at the end of life, what we have yet to learn, and what we know but do not adequately apply. It seeks to build understanding of what constitutes good care for the dying and offers recommendations to decisionmakers that address specific barriers to achieving good care. This volume offers a profile of when, where, and how Americans die. It examines the dimensions of caring at the end of life: Determining diagnosis and prognosis and communicating these to patient and family. Establishing clinical and personal goals. Matching physical, psychological, spiritual, and practical care strategies to the patient's values and circumstances. Approaching Death considers the dying experience in hospitals, nursing homes, and other settings and the role of interdisciplinary teams and managed care. It offers perspectives on quality measurement and improvement, the role of practice guidelines, cost concerns, and legal issues such as assisted suicide. The book proposes how health professionals can become better prepared to care well for those who are dying and to understand that these are not patients for whom "nothing can be done."

Modern Methods of Clinical Investigation

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Publisher : National Academies Press
ISBN 13 : 0309042860
Total Pages : 241 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Modern Methods of Clinical Investigation by : Institute of Medicine

Download or read book Modern Methods of Clinical Investigation written by Institute of Medicine and published by National Academies Press. This book was released on 1990-02-01 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: The very rapid pace of advances in biomedical research promises us a wide range of new drugs, medical devices, and clinical procedures. The extent to which these discoveries will benefit the public, however, depends in large part on the methods we choose for developing and testing them. Modern Methods of Clinical Investigation focuses on strategies for clinical evaluation and their role in uncovering the actual benefits and risks of medical innovation. Essays explore differences in our current systems for evaluating drugs, medical devices, and clinical procedures; health insurance databases as a tool for assessing treatment outcomes; the role of the medical profession, the Food and Drug Administration, and industry in stimulating the use of evaluative methods; and more. This book will be of special interest to policymakers, regulators, executives in the medical industry, clinical researchers, and physicians.

Oxford Guide to CBT for People with Cancer

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Publisher : Oxford University Press
ISBN 13 : 0199605807
Total Pages : 299 pages
Book Rating : 4.1/5 (996 download)

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Book Synopsis Oxford Guide to CBT for People with Cancer by : Stirling Moorey

Download or read book Oxford Guide to CBT for People with Cancer written by Stirling Moorey and published by Oxford University Press. This book was released on 2011-11-24 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rev. ed. of: Cognitive behaviour therapy for people with cancer / Stirling Moorey and Steven Greer. 2002.

Dying in America

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Publisher : National Academies Press
ISBN 13 : 0309303133
Total Pages : 470 pages
Book Rating : 4.3/5 (93 download)

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Book Synopsis Dying in America by : Institute of Medicine

Download or read book Dying in America written by Institute of Medicine and published by National Academies Press. This book was released on 2015-03-19 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt: For patients and their loved ones, no care decisions are more profound than those made near the end of life. Unfortunately, the experience of dying in the United States is often characterized by fragmented care, inadequate treatment of distressing symptoms, frequent transitions among care settings, and enormous care responsibilities for families. According to this report, the current health care system of rendering more intensive services than are necessary and desired by patients, and the lack of coordination among programs increases risks to patients and creates avoidable burdens on them and their families. Dying in America is a study of the current state of health care for persons of all ages who are nearing the end of life. Death is not a strictly medical event. Ideally, health care for those nearing the end of life harmonizes with social, psychological, and spiritual support. All people with advanced illnesses who may be approaching the end of life are entitled to access to high-quality, compassionate, evidence-based care, consistent with their wishes. Dying in America evaluates strategies to integrate care into a person- and family-centered, team-based framework, and makes recommendations to create a system that coordinates care and supports and respects the choices of patients and their families. The findings and recommendations of this report will address the needs of patients and their families and assist policy makers, clinicians and their educational and credentialing bodies, leaders of health care delivery and financing organizations, researchers, public and private funders, religious and community leaders, advocates of better care, journalists, and the public to provide the best care possible for people nearing the end of life.

International Ethical Guidelines for Health-Related Research Involving Humans

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Author :
Publisher : World Health Organization
ISBN 13 : 9789290360889
Total Pages : 0 pages
Book Rating : 4.3/5 (68 download)

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Book Synopsis International Ethical Guidelines for Health-Related Research Involving Humans by : Council for International Organizations of Medical Sciences (CIOMS)

Download or read book International Ethical Guidelines for Health-Related Research Involving Humans written by Council for International Organizations of Medical Sciences (CIOMS) and published by World Health Organization. This book was released on 2017-01-31 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "In the new 2016 version of the ethical guidelines, CIOMS provides answers to a number of pressing issues in research ethics. The Council does so by stressing the need for research having scientific and social value, by providing special guidelines for health-related research in low-resource settings, by detailing the provisions for involving vulnerable groups in research and for describing under what conditions biological samples and health-related data can be used for research."--Page 4 de la couverture.

The Right to Try

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Publisher : HarperCollins
ISBN 13 : 0062407546
Total Pages : 178 pages
Book Rating : 4.0/5 (624 download)

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Book Synopsis The Right to Try by : Darcy Olsen

Download or read book The Right to Try written by Darcy Olsen and published by HarperCollins. This book was released on 2015-11-10 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt: Why should you need the government’s permission to save your own life? Jenn McNary’s two sons, Max and Austin, were diagnosed with Duchenne muscular dystrophy—a fatal disorder that leads to muscle degeneration and eventually death. In a cruel and unnecessary twist, Max received access to a clinical trial; Austin didn’t. As a result, Max was able to get out of his wheelchair and play on his school soccer team while Austin continued to deteriorate until he could not even feed himself. The FDA takes as long as fifteen years to approve a new drug, demanding near-absolute proof of effectiveness before allowing commercial distribution. But this ignores the urgent plight of millions of terminally ill Americans who have run out of approved options—and are running out of time. These patients are not looking for a 100 percent guarantee that a treatment will work for them. They are looking for a fighting chance. Why can’t they have that chance? Why don’t they have the right to try . . . the right to save their own lives? Author and activist Darcy Olsen, president of the Goldwater Institute, tells the remarkable story behind the Right to Try movement, the national campaign to give dying Americans access to cutting-edge treatments that are under study but still years away from receiving the FDA’s green light. The men, women, and children featured in these pages are our own family members, friends, and neighbors. Their heartbreaking, triumphant, and inspirational stories prove the necessity for Right to Try laws. Because everyone deserves the Right to Try.

The History of Oncology

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Publisher : Bohn Stafleu van Loghum
ISBN 13 : 9789031361434
Total Pages : 318 pages
Book Rating : 4.3/5 (614 download)

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Book Synopsis The History of Oncology by : D. J. Th. Wagener

Download or read book The History of Oncology written by D. J. Th. Wagener and published by Bohn Stafleu van Loghum. This book was released on 2009-07-13 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: ‘The story of oncology is not only fascinating but also contains many accounts of dead ends, chance discoveries, illusions, mistakes and disappointments alongside the few successes.’These words are taken from the introduction to this book. The author, professor emeritus of Medical Oncology, reviews all aspects of the problem of cancer from a historical perspective, from the oldest existing records to the latest scientific and medical advances. It will interest the many people engaged in the treatment of cancer to read how the current therapeutic methods came about, and the book may also provide inspiration for cancer researchers, and for all those directly or indirectly involved with cancer. The layman looking for background information on a particular treatment may find it useful too. The various chapters can be read independently. A glossary and a few explanatory diagrams augment the text.This book grew out of an invitation the author received to lecture on the history of oncology. During his background reading, he discovered that there was no single volume dealing with the entire history of the subject. Fortunately, however, a great deal of information could be found here and there in the literature. As he read, he was struck by the fascinating stories behind many discoveries, and felt impelled to put them together in a single comprehensive account. The results of his labors are presented in this remarkable volume.The author, Prof. D.J.Th. (Theo) Wagener, was head of the department of Medical Oncology at the Radboud University Nijmegen Medical Centre in the Netherlands from 1982 to 2001, chairman of the Educational Committee of the European Society of Medical Oncology (ESMO), a member of the Educational Committee of the American Society of Clinical Oncology (ASCO) and a member of various international scientific working groups, mainly of the European Organization for Research and Treatment of Cancer (EORTC).

How to Change Your Mind

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Author :
Publisher : Penguin
ISBN 13 : 0525558942
Total Pages : 481 pages
Book Rating : 4.5/5 (255 download)

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Book Synopsis How to Change Your Mind by : Michael Pollan

Download or read book How to Change Your Mind written by Michael Pollan and published by Penguin. This book was released on 2018-05-15 with total page 481 pages. Available in PDF, EPUB and Kindle. Book excerpt: “Pollan keeps you turning the pages . . . cleareyed and assured.” —New York Times A #1 New York Times Bestseller, New York Times Book Review 10 Best Books of 2018, and New York Times Notable Book A brilliant and brave investigation into the medical and scientific revolution taking place around psychedelic drugs--and the spellbinding story of his own life-changing psychedelic experiences When Michael Pollan set out to research how LSD and psilocybin (the active ingredient in magic mushrooms) are being used to provide relief to people suffering from difficult-to-treat conditions such as depression, addiction and anxiety, he did not intend to write what is undoubtedly his most personal book. But upon discovering how these remarkable substances are improving the lives not only of the mentally ill but also of healthy people coming to grips with the challenges of everyday life, he decided to explore the landscape of the mind in the first person as well as the third. Thus began a singular adventure into various altered states of consciousness, along with a dive deep into both the latest brain science and the thriving underground community of psychedelic therapists. Pollan sifts the historical record to separate the truth about these mysterious drugs from the myths that have surrounded them since the 1960s, when a handful of psychedelic evangelists inadvertently catalyzed a powerful backlash against what was then a promising field of research. A unique and elegant blend of science, memoir, travel writing, history, and medicine, How to Change Your Mind is a triumph of participatory journalism. By turns dazzling and edifying, it is the gripping account of a journey to an exciting and unexpected new frontier in our understanding of the mind, the self, and our place in the world. The true subject of Pollan's "mental travelogue" is not just psychedelic drugs but also the eternal puzzle of human consciousness and how, in a world that offers us both suffering and joy, we can do our best to be fully present and find meaning in our lives.

Let the Record Show

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Author :
Publisher : Farrar, Straus and Giroux
ISBN 13 : 0374719950
Total Pages : 505 pages
Book Rating : 4.3/5 (747 download)

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Book Synopsis Let the Record Show by : Sarah Schulman

Download or read book Let the Record Show written by Sarah Schulman and published by Farrar, Straus and Giroux. This book was released on 2021-05-18 with total page 505 pages. Available in PDF, EPUB and Kindle. Book excerpt: Winner of the 2022 Lambda Literary LGBTQ Nonfiction Award and the 2022 NLGJA Excellence in Book Writing Award. Finalist for the PEN/John Kenneth Galbriath Award for Nonfiction, the Gotham Book Prize, and the ALA Stonewall Israel Fishman Nonfiction Award. A 2021 New York Times Book Review Notable Book and a New York Times Book Review Editors' Choice. Longlisted for the 2021 Brooklyn Public Library Literary Prize. One of NPR, New York, and The Guardian's Best Books of 2021, one of Buzzfeed's Best LGBTQ+ Books of 2021, one of Electric Literature's Favorite Nonfiction Books of 2021, one of NBC's 10 Most Notable LGBTQ Books of 2021, and one of Gay Times' Best LGBTQ Books of 2021. "This is not reverent, definitive history. This is a tactician’s bible." --Parul Sehgal, The New York Times Twenty years in the making, Sarah Schulman's Let the Record Show is the most comprehensive political history ever assembled of ACT UP and American AIDS activism In just six years, ACT UP, New York, a broad and unlikely coalition of activists from all races, genders, sexualities, and backgrounds, changed the world. Armed with rancor, desperation, intelligence, and creativity, it took on the AIDS crisis with an indefatigable, ingenious, and multifaceted attack on the corporations, institutions, governments, and individuals who stood in the way of AIDS treatment for all. They stormed the FDA and NIH in Washington, DC, and started needle exchange programs in New York; they took over Grand Central Terminal and fought to change the legal definition of AIDS to include women; they transformed the American insurance industry, weaponized art and advertising to push their agenda, and battled—and beat—The New York Times, the Catholic Church, and the pharmaceutical industry. Their activism, in its complex and intersectional power, transformed the lives of people with AIDS and the bigoted society that had abandoned them. Based on more than two hundred interviews with ACT UP members and rich with lessons for today’s activists, Let the Record Show is a revelatory exploration—and long-overdue reassessment—of the coalition’s inner workings, conflicts, achievements, and ultimate fracture. Schulman, one of the most revered queer writers and thinkers of her generation, explores the how and the why, examining, with her characteristic rigor and bite, how a group of desperate outcasts changed America forever, and in the process created a livable future for generations of people across the world.

CDC Yellow Book 2018: Health Information for International Travel

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Author :
Publisher : Oxford University Press
ISBN 13 : 0190628634
Total Pages : 705 pages
Book Rating : 4.1/5 (96 download)

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Book Synopsis CDC Yellow Book 2018: Health Information for International Travel by : Centers for Disease Control and Prevention CDC

Download or read book CDC Yellow Book 2018: Health Information for International Travel written by Centers for Disease Control and Prevention CDC and published by Oxford University Press. This book was released on 2017-04-17 with total page 705 pages. Available in PDF, EPUB and Kindle. Book excerpt: THE ESSENTIAL WORK IN TRAVEL MEDICINE -- NOW COMPLETELY UPDATED FOR 2018 As unprecedented numbers of travelers cross international borders each day, the need for up-to-date, practical information about the health challenges posed by travel has never been greater. For both international travelers and the health professionals who care for them, the CDC Yellow Book 2018: Health Information for International Travel is the definitive guide to staying safe and healthy anywhere in the world. The fully revised and updated 2018 edition codifies the U.S. government's most current health guidelines and information for international travelers, including pretravel vaccine recommendations, destination-specific health advice, and easy-to-reference maps, tables, and charts. The 2018 Yellow Book also addresses the needs of specific types of travelers, with dedicated sections on: · Precautions for pregnant travelers, immunocompromised travelers, and travelers with disabilities · Special considerations for newly arrived adoptees, immigrants, and refugees · Practical tips for last-minute or resource-limited travelers · Advice for air crews, humanitarian workers, missionaries, and others who provide care and support overseas Authored by a team of the world's most esteemed travel medicine experts, the Yellow Book is an essential resource for travelers -- and the clinicians overseeing their care -- at home and abroad.

Medicare Hospice Benefits

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Author :
Publisher :
ISBN 13 :
Total Pages : 6 pages
Book Rating : 4.:/5 (285 download)

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Book Synopsis Medicare Hospice Benefits by :

Download or read book Medicare Hospice Benefits written by and published by . This book was released on 1993 with total page 6 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Taking Your Medicine

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Author :
Publisher :
ISBN 13 : 9780674592759
Total Pages : 288 pages
Book Rating : 4.5/5 (927 download)

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Book Synopsis Taking Your Medicine by : Elisha Gray II Professor of Economics Emeritus Peter Temin

Download or read book Taking Your Medicine written by Elisha Gray II Professor of Economics Emeritus Peter Temin and published by . This book was released on 2013-10-01 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: