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A Theoretical Analysis Of Singularity Induced Micro Electroporation And Its Applications
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Book Synopsis A Theoretical Analysis of Singularity-induced Micro-electroporation and Its Applications by : Gregory David Troszak
Download or read book A Theoretical Analysis of Singularity-induced Micro-electroporation and Its Applications written by Gregory David Troszak and published by . This book was released on 2011 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: Electroporation - the permeabilization of the cell membrane lipid bilayer due to a pulsed electric field - has important implications in the biotechnology, medicine, and food industries. Although the physical mechanism that causes electroporation is not entirely understood, it is believed that pulsed electric fields significantly increase the potential difference across the cell membrane, resulting in the formation of pores. Depending on the magnitude and duration of a pulsed electric field, membrane permeabilization is either reversible or irreversible. Reversible electroporation is commonly used to transfer macromolecules such as proteins, DNA, or drugs into cells, and the destructive nature of irreversible electroporation makes it suitable for cell ablation and sterilization. Most electroporation devices have facing electrodes that generate uniform electric fields. Consequently, the magnitudes of these electric fields are inversely proportional to the distance between the electrodes. Since reversible and irreversible electroporation require electric field magnitudes on the order of 1 and 10 kV/cm, respectively, large potential differences are required to induce electroporation. Reducing the potential difference required to perform electroporation eliminates the need for a power supply, making electroporation cheaper and more accessible. Singularity-induced micro-electroporation - an electroporation configuration composed of two adjacent electrodes separated by a nanoscale insulator - aims to reduce the potential difference required to perform electroporation. Application of a small potential difference between the electrodes creates a radially varying electric field emanating from the insulator. Secondary current distribution models of singularity-induced micro-electroporation show that applying a potential difference as low as 2.9 V creates an electric field that is capable of inducing reversible and irreversible electroporation. To date, the lowest potential difference used to perform irreversible electroporation is 2̃0 V. More impressively, these models demonstrate that the ohmic drops in galvanic electrochemical cells can generate electroporation-inducing electric fields, enabling the creation of a self-powered micro-electroporation device.
Book Synopsis Disorder and Strain-Induced Complexity in Functional Materials by : Tomoyuki Kakeshita
Download or read book Disorder and Strain-Induced Complexity in Functional Materials written by Tomoyuki Kakeshita and published by Springer Science & Business Media. This book was released on 2011-10-27 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book brings together an emerging consensus on our understanding of the complex functional materials including ferroics, perovskites, multiferroics, CMR and high-temperature superconductors. The common theme is the existence of many competing ground states and frustration as a collusion of spin, charge, orbital and lattice degrees of freedom in the presence of disorder and (both dipolar and elastic) long-range forces. An important consequence of the complex unit cell and the competing interactions is that the emergent materials properties are very sensitive to external fields thus rendering these materials with highly desirable, technologically important applications enabled by cross-response.
Book Synopsis Integrative Biophysics by : Fritz-Albert Popp
Download or read book Integrative Biophysics written by Fritz-Albert Popp and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 499 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most of the specialists working in this interdisciplinary field of physics, biology, biophysics and medicine are associated with "The International Institute of Biophysics" (IIB), in Neuss, Germany, where basic research and possibilities for applications are coordinated. The growth in this field is indicated by the increase in financial support, interest from the scientific community and frequency of publications. Audience: The scientists of IIB have presented the most essential background and applications of biophotonics in these lecture notes in biophysics, based on the summer school lectures by this group. This book is devoted to questions of elementary biophysics, as well as current developments and applications. It will be of interest to graduate and postgraduate students, life scientists, and the responsible officials of industries and governments looking for non-invasive methods of investigating biological tissues.
Book Synopsis Molecular- and Nano-Tubes by : Oliver Hayden
Download or read book Molecular- and Nano-Tubes written by Oliver Hayden and published by Springer Science & Business Media. This book was released on 2011-08-04 with total page 477 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular- and Nano-Tubes summarizes recent advancements in the synthesis, fabrication and applications of tubular structures. An interdisciplinary overview of innovative science focused on tubular structures is provided. The reader is offered an overview of the different fields that molecular and nano tubes appear in, in order to learn the fundamental basics as well as the applications of these materials. This book also: Shows how nanotechnology creates novel materials by crossing the barriers between biology and material science, electronics and optics, medicine and more Demonstrates that tubes are a fundamental element in nature and used in disparate applications such as ion channels and carbon nanotubes Molecular- and Nano-Tubes is an ideal volume for researchers and engineers working in materials science and nanotechnology.
Book Synopsis Cardiac Mapping by : Mohammad Shenasa
Download or read book Cardiac Mapping written by Mohammad Shenasa and published by John Wiley & Sons. This book was released on 2019-04-04 with total page 1304 pages. Available in PDF, EPUB and Kindle. Book excerpt: The expanded guide to cardiac mapping The effective diagnosis and treatment of heart disease may vitally depend upon accurate and detailed cardiac mapping. However, in an era of rapid technological advancement, medical professionals can encounter difficulties maintaining an up-to-date knowledge of current methods. This fifth edition of the much-admired Cardiac Mapping is, therefore, essential, offering a level of cutting-edge insight that is unmatched in its scope and depth. Featuring contributions from a global team of electrophysiologists, the book builds upon previous editions' comprehensive explanations of the mapping, imaging, and ablation of the heart. Nearly 100 chapters provide fascinating accounts of topics ranging from the mapping of supraventricular and ventriculararrhythmias, to compelling extrapolations of how the field might develop in the years to come. In this text, readers will find: Full coverage of all aspects of cardiac mapping, and imaging Explorations of mapping in experimental models of arrhythmias Examples of new catheter-based techniques Access to a companion website featuring additional content and illustrative video clips Cardiac Mapping is an indispensable resource for scientists, clinical electrophysiologists, cardiologists, and all physicians who care for patients with cardiac arrhythmias.
Book Synopsis Women in Biotechnology by : Francesca Molfino
Download or read book Women in Biotechnology written by Francesca Molfino and published by Springer Science & Business Media. This book was released on 2008-08-05 with total page 359 pages. Available in PDF, EPUB and Kindle. Book excerpt: Johannes Klumpers Biotechnologies, such as genetic engineering, cloning and biodiversity, raise many legal and ethical concerns, so it is important that people understand these issues and feel able to express their opinions. This is why the European Commission has been, for a number of years, supporting actions to improve communication among scientists in these diverse areas. The project ‘Women in Biotechnology’ (WONBIT), financed under the 6th Framework programme of the European Commission, is an excellent example of what can be done to target opinion-formers such as scientists, economists and lawyers in bottom-up activities, and to encourage a debate on gender issues triggered by developments in the life sciences. WONBIT gave rise to a successful international conference highlighting the importance of adopting good practices and ethical considerations in parallel with the rapid pace of progress in biotechnology – from a woman’s point of view. In particular, the conference addressed women in decision-making positions in b- technology with specific reference to scientific excellence, social competencies and management qualities as well as issues relating to environment, society and the younger generation. But it did not stop there: a key part of the conference was dedicated to stimulating public debate among non-specialists, which has led to a number of recommen- tions to policy-makers on better communication in biotechnology, on taking better account of the gender aspects of research, and on involving more women in the decision-making process that surrounds developments in biotechnology.
Book Synopsis E. coli Plasmid Vectors by : Nicola Casali
Download or read book E. coli Plasmid Vectors written by Nicola Casali and published by Humana Press. This book was released on 2010-11-10 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive collection of readily reproducible techniques for the manipulation of recombinant plasmids using the bacterial host E. coli. The authors describe proven methods for cloning DNA into plasmid vectors, transforming plasmids into E. coli, and analyzing recombinant clones. They also include protocols for the construction and screening of libraries, as well as specific techniques for specialized cloning vehicles, such as cosmids, bacterial artificial chromosomes, l vectors, and phagemids. Common downstream applications such as mutagenesis of plasmids, recombinant protein expression, and the use of reporter genes, are also described.
Book Synopsis Integration of Insect-Resistant Genetically Modified Crops within IPM Programs by : Jörg Romeis
Download or read book Integration of Insect-Resistant Genetically Modified Crops within IPM Programs written by Jörg Romeis and published by Springer Science & Business Media. This book was released on 2008-07-01 with total page 451 pages. Available in PDF, EPUB and Kindle. Book excerpt: Insect pests remain one of the main constraints to food and fiber production worldwide despite farmers deploying a range of techniques to protect their crops. Modern pest control is guided by the principles of integrated pest management (IPM) with pest resistant germplasm being an important part of the foundation. Since 1996, when the first genetically modified (GM) insect-resistant maize variety was commercialized in the USA, the area planted to insect-resistant GM varieties has grown dramatically, representing the fastest adoption rate of any agricultural technology in human history. The goal of our book is to provide an overview on the role insect-resistant GM plants play in different crop systems worldwide. We hope that the book will contribute to a more rational debate about the role GM crops can play in IPM for food and fiber production.
Book Synopsis Plant Electrophysiology by : Alexander G. Volkov
Download or read book Plant Electrophysiology written by Alexander G. Volkov and published by Springer Science & Business Media. This book was released on 2007-04-19 with total page 513 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book compiles new findings in plant electrophysiology from the work of internationally renowned experts in the fields of electrophysiology, bio-electrochemistry, biophysics, signal transduction, phloem transport, tropisms, ion channels, plant electrochemistry, and membrane transport. Opening with a historical introduction, the book reviews methods in plant electrophysiology, introducing such topics as measuring membrane potentials and ion fluxes, path-clamp technique, and electrochemical sensors. The coverage includes experimental results and their theoretical interpretation.
Book Synopsis 5th European Conference of the International Federation for Medical and Biological Engineering 14 - 18 September 2011, Budapest, Hungary by : Ákos Jobbágy
Download or read book 5th European Conference of the International Federation for Medical and Biological Engineering 14 - 18 September 2011, Budapest, Hungary written by Ákos Jobbágy and published by Springer Science & Business Media. This book was released on 2012-02-02 with total page 1477 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume presents the 5th European Conference of the International Federation for Medical and Biological Engineering (EMBEC), held in Budapest, 14-18 September, 2011. The scientific discussion on the conference and in this conference proceedings include the following issues: - Signal & Image Processing - ICT - Clinical Engineering and Applications - Biomechanics and Fluid Biomechanics - Biomaterials and Tissue Repair - Innovations and Nanotechnology - Modeling and Simulation - Education and Professional
Book Synopsis Design and Implementation of Portable Impedance Analyzers by : Abdulwadood A. Al-Ali
Download or read book Design and Implementation of Portable Impedance Analyzers written by Abdulwadood A. Al-Ali and published by Springer. This book was released on 2019-02-23 with total page 90 pages. Available in PDF, EPUB and Kindle. Book excerpt: The increasing interest in the bio-impedance analysis in various fields has increased the demand for portable and low-cost impedance analyzers that can be used in the field. Simplifying the hardware is crucial to maintaining low-cost and portability, but this is not an easy task due to the need for accurate phase and magnitude measurements. This book discusses different portable impedance analyzers design techniques. Additionally, complete designs using two different approaches are reported. The first approach utilizes a commercially available single chip solution while the second one is based on a new measurement technique that eliminates the need to measure the phase by using a software algorithm to extract it from the magnitude information. Applications to the measurement of fruit bio-impedance are emphasized and compared with measurements from professional stand-alone impedance analyzers.
Book Synopsis Dorland's Dictionary of Medical Acronyms and Abbreviations E-Book by : Dorland
Download or read book Dorland's Dictionary of Medical Acronyms and Abbreviations E-Book written by Dorland and published by Elsevier Health Sciences. This book was released on 2015-07-24 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medical acronyms and abbreviations offer convenience, but those countless shortcuts can often be confusing. Now a part of the popular Dorland’s suite of products, this reference features thousands of terms from across various medical specialties. Its alphabetical arrangement makes for quick reference, and expanded coverage of symbols ensures they are easier to find. Effective communication plays an important role in all medical settings, so turn to this trusted volume for nearly any medical abbreviation you might encounter. Symbols section makes it easier to locate unusual or seldom-used symbols. Convenient alphabetical format allows you to find the entry you need more intuitively. More than 90,000 entries and definitions. Many new and updated entries including terminology in expanding specialties, such as Nursing; Physical, Occupational, and Speech Therapies; Transcription and Coding; Computer and Technical Fields. New section on abbreviations to avoid, including Joint Commission abbreviations that are not to be used. Incorporates updates suggested by the Institute for Safe Medication Practices (ISMP).
Download or read book Consilience written by E. O. Wilson and published by Vintage. This book was released on 2014-11-26 with total page 485 pages. Available in PDF, EPUB and Kindle. Book excerpt: NATIONAL BESTSELLER • "A dazzling journey across the sciences and humanities in search of deep laws to unite them." —The Wall Street Journal One of our greatest scientists—and the winner of two Pulitzer Prizes for On Human Nature and The Ants—gives us a work of visionary importance that may be the crowning achievement of his career. In Consilience (a word that originally meant "jumping together"), Edward O. Wilson renews the Enlightenment's search for a unified theory of knowledge in disciplines that range from physics to biology, the social sciences and the humanities. Using the natural sciences as his model, Wilson forges dramatic links between fields. He explores the chemistry of the mind and the genetic bases of culture. He postulates the biological principles underlying works of art from cave-drawings to Lolita. Presenting the latest findings in prose of wonderful clarity and oratorical eloquence, and synthesizing it into a dazzling whole, Consilience is science in the path-clearing traditions of Newton, Einstein, and Richard Feynman.
Book Synopsis Stochastic Dynamics by : Lutz Schimansky-Geier
Download or read book Stochastic Dynamics written by Lutz Schimansky-Geier and published by Springer. This book was released on 2014-03-12 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stochastic Dynamics, born almost 100 years ago with the early explanations of Brownian motion by physicists, is nowadays a quickly expanding field of research within nonequilibrium statistical physics. The present volume provides a survey on the influence of fluctuations in nonlinear dynamics. It addresses specialists, although the intention of this book is to provide teachers and students with a reliable resource for seminar work. In particular, the reader will find many examples illustrating the theory as well as a host of recent findings.
Book Synopsis 7th International Conference on the Development of Biomedical Engineering in Vietnam (BME7) by : Vo Van Toi
Download or read book 7th International Conference on the Development of Biomedical Engineering in Vietnam (BME7) written by Vo Van Toi and published by Springer. This book was released on 2019-06-05 with total page 730 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume presents the proceedings of the 7th International Conference on the Development of Biomedical Engineering in Vietnam which was held from June 27-29, 2018 in Ho Chi Minh City. The volume reflects the progress of Biomedical Engineering and discusses problems and solutions. It aims to identify new challenges, and shaping future directions for research in biomedical engineering fields including medical instrumentation, bioinformatics, biomechanics, medical imaging, drug delivery therapy, regenerative medicine and entrepreneurship in medical devices.
Book Synopsis Singularity Hypotheses by : Amnon H. Eden
Download or read book Singularity Hypotheses written by Amnon H. Eden and published by Springer Science & Business Media. This book was released on 2013-04-03 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: Singularity Hypotheses: A Scientific and Philosophical Assessment offers authoritative, jargon-free essays and critical commentaries on accelerating technological progress and the notion of technological singularity. It focuses on conjectures about the intelligence explosion, transhumanism, and whole brain emulation. Recent years have seen a plethora of forecasts about the profound, disruptive impact that is likely to result from further progress in these areas. Many commentators however doubt the scientific rigor of these forecasts, rejecting them as speculative and unfounded. We therefore invited prominent computer scientists, physicists, philosophers, biologists, economists and other thinkers to assess the singularity hypotheses. Their contributions go beyond speculation, providing deep insights into the main issues and a balanced picture of the debate.
Book Synopsis Ahead of the Curve by : Michael Levin
Download or read book Ahead of the Curve written by Michael Levin and published by Iph001. This book was released on 2019-01-31 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: The popular conception of science is of a steady, upward climb of progress. The reality is not that simple. Highly significant discoveries often stay unrecognized for decades, particularly if they conflict with the current paradigm or extend it in ways hard to imagine at the time. Ahead of the Curve: Hidden breakthroughs in the biosciences is a fascinating collection of lost research that the editors believe are important scientific contributions.
