Read Books Online and Download eBooks, EPub, PDF, Mobi, Kindle, Text Full Free.
Download A Role For Reactive Oxygen Species In Apoptotic Cell Death full books in PDF, epub, and Kindle. Read online A Role For Reactive Oxygen Species In Apoptotic Cell Death ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Author : James T. Wolfe
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (54 download)
Download or read book A Role for Reactive Oxygen Species in Apoptotic Cell Death written by James T. Wolfe and published by . This book was released on 1996 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Denis Martinvalet
Publisher : Frontiers Media SA
ISBN 13 : 2889745287
Total Pages : 176 pages
Book Rating : 4.8/5 (897 download)
Download or read book The Role of Reactive Oxygen Species in Protective Immunity written by Denis Martinvalet and published by Frontiers Media SA. This book was released on 2022-02-25 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Loutfy H. Madkour
Publisher : Academic Press
ISBN 13 : 0128224967
Total Pages : 782 pages
Book Rating : 4.1/5 (282 download)
Download or read book Reactive Oxygen Species (ROS), Nanoparticles, and Endoplasmic Reticulum (ER) Stress-Induced Cell Death Mechanisms written by Loutfy H. Madkour and published by Academic Press. This book was released on 2020-06-27 with total page 782 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reactive Oxygen Species (ROS), Nanoparticles, and Endoplasmic Reticulum (ER) Stress-Induced Cell Death Mechanisms presents the role of ROS?mediated pathways cellular signaling stress, endoplasmic reticulum (ER) stress, oxidative stress, oxidative damage, nanomaterials, and the mechanisms by which metalloids and nanoparticles induce their toxic effects. The book covers the ecotoxicology of environmental heavy metal ions and free radicals on macromolecules cells organisms, heavy metals?induced cell responses, oxidative stress, the source of oxidants, and the roles of ROS, oxidative stress and oxidative damage mechanisms. It also examines the nanotoxicity, cytotoxicity and genotoxicity mechanisms of nanomaterials and the effects of nanoparticle interactions. Antioxidant defense therapy and strategies for treatment round out the book, making it an ideal resource for researchers and professional scientists in toxicology, environmental chemistry, environmental science, nanomaterials and the pharmaceutical sciences. Covers the ecotoxicology of environmental heavy metal ions and the interactions between specific heavy metals?induced cell responses and oxidative stress Provides a better understanding of the mechanism of nanomaterial-induced toxicity as a first defense for hazard prevention Covers recent advances in new nanomedication technologies for the effects of NPs on oxidative stress, ROS and ER stress Discusses the effects of interactions between antioxidant defense therapy, ROS and strategies for treatment
Author : Ismail Laher
Publisher : Springer
ISBN 13 : 9783642300172
Total Pages : 0 pages
Book Rating : 4.3/5 (1 download)
Download or read book Systems Biology of Free Radicals and Antioxidants written by Ismail Laher and published by Springer. This book was released on 2014-06-16 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The focus of this collection of illustrated reviews is to discuss the systems biology of free radicals and anti-oxidants. Free radical induced cellular damage in a variety of tissues and organs is reviewed, with detailed discussion of molecular and cellular mechanisms. The collection is aimed at those new to the field, as well as clinicians and scientists with long standing interests in free radical biology. A feature of this collection is that the material also brings insights into various diseases where free radicals are thought to play a role. There is extensive discussion of the success and limitations of the use of antioxidants in several clinical settings.
Author : Ghada Mahmoud Abou-Lteif
Publisher :
ISBN 13 :
Total Pages : 176 pages
Book Rating : 4.:/5 (787 download)
Download or read book Role of Reactive Oxygen Species in N-(4-hydroxyphenyl)retinamide-induced Cell Death in HTLV-I-transformed Cells and Malignant T Cell Lines written by Ghada Mahmoud Abou-Lteif and published by . This book was released on 2008 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt: N-(4-hydroxyphenyl)retinamide (HPR) is a synthetic retinoid that inhibits growth and induces apoptosis in many human cell lines including those that are resista nt to natural retinoids. Adult T-cell leukemia-lymphoma (ATL) is an aggressive peripheral T-cell malignancy caused by human T-cell lymphotropic virus type I (H TLV-I). ATL carries a poor prognosis with a mean survival time of less than eig ht months, in the acute form, mainly due to acquired resistance to chemotherapy. The viral transactivator protein Tax plays a critical role in HTLV-I-induced t ransformation and apoptosis resistance. We have previously shown that HPR inhibits proliferation and induces apoptosis i n all tested ATL and HTLV-I-negative malignant T cell lines, while no effect is observed on normal lymphocytes (Darwiche 2004). The mechanisms of HPR-induced c ell death are complex and involve signaling pathways mediated by free radicals o r reactive oxygen species (ROS). Using ATL as a model, we aim at deciphering th e mechanisms generating ROS and apoptosis of malignant T cells in response to HP R. We will explore the involvement of ROS in HPR-induced apoptosis, the contrib ution of the different biochemical pathways of ROS generation in relation to HPR -induced cell death; and Tax modulation of HPR induced ROS accumulation and ROS- induced cell death. We identified HPR-induced ROS generation as the key mediator of cell cycle arres t and apoptosis of malignant T cells. Pre-treatment with antioxidants inhibited ROS generation, prevented HPR-induced ceramide accumulation, cell cycle arrest, cytochrome c release, caspase-activation and apoptosis. The expression of the HTLV-I oncoprotein Tax abrogated HPR-induced ROS accumulation in HTLV-I-infected cells, which explains their lower sensitivity to HPR. Of the enzyme systems fr equently implicated in ROS generation, only phospholipase A2 (PLA2) and lipooxyg enase (LOX) were shown to be involved in ROS generation and growth suppression i n response to HPR in HTLV-I-negative malignant T cells Defining the mechanism of free radical induction by HPR may support a potential therapeutic role for this synthetic retinoid in ATL and HTLV-I-negative T-cell l ymphomas.
Author : Gines Maria Salido
Publisher : Springer Science & Business Media
ISBN 13 : 1402098731
Total Pages : 239 pages
Book Rating : 4.4/5 (2 download)
Download or read book Apoptosis: Involvement of Oxidative Stress and Intracellular Ca2+ Homeostasis written by Gines Maria Salido and published by Springer Science & Business Media. This book was released on 2009-03-08 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: Apoptosis: Involvement of Oxidative Stress and Intracellular Ca2+ Homeostasis, presents a concise synthesis of the current knowledge and recent advances in the mechanisms of apoptosis in different cells and the role of oxidative stress and Ca2+ signalling. Particular attention is given to the different features of apoptosis in distinct cell types, ranging from hepatocytes to cardiovascular and blood cells, nervous cells or spermatozoa. Cutting-edge and user-friendly, this volume serves as a comprehensive resource for those interested in the fascinating biological processes associated to programmed cell death or apoptosis. The book is divided in two major chapter sections: general mechanisms of the apoptotic pathways and the role of oxidative stress and intracellular Ca2+ homeostasis and a more specific section dedicated to the specificities of apoptosis in a number of excitable and non-excitable cells. All of the contributions are from specialists in the field and the reviews presented, systemically examine the most exciting and innovative aspects of the apoptotic pathways in their particular areas of expertise.
Author : Kuladip Jana
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.8/5 (911 download)
Download or read book The Role of Reactive Oxygen Species in Health and Disease written by Kuladip Jana and published by . This book was released on 2024 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Reactive oxygen species (ROS) play an essential role in different biological functions, including physiological regulatory mechanisms to damaging alterations involved in the pathogenesis of an increasing number of human diseases. ROS are metabolic products from numerous cells, but two vital cellular organelles are intimately involved in their production and metabolism, i.e. the endoplasmic reticulum and the mitochondria. Excess cellular levels of ROS may cause damage to proteins, nucleic acids, lipids, membranes, and organelles, which may lead to the activation of cell death processes such as apoptosis. Apoptosis is a highly regulated process that is essential for the development and survival of multicellular organisms. These organisms often need to discard superfluous or potentially harmful cells, have accumulated mutations, or become infected by pathogens. Apoptosis features a characteristic set of morphological and biochemical features whereby cells undergo a cascade of self-destruction. Thus, proper regulation of apoptosis is essential for maintaining normal cellular homeostasis. Mitochondrial ROS (mtROS) play a central role in cell signaling and regulating the main pathways of apoptosis, mediated by mitochondria, death receptors, and the endoplasmic reticulum (ER) stress. This book focuses on the current understanding of the role of ROS in each of these three main pathways of apoptosis related to different human diseases, with particular emphasis on Metabolic, Inflammatory, Neurodegenerative, and Neoplastic diseases. It's promise and limitations are also discussed by targeting ROS with different antioxidants in preventing non-communicable diseases. The role of mtROS in the complex interplay and crosstalk between these different signaling pathways of apoptosis related to different human diseases remains to be unraveled further in future research"--
Author : Irene Ceballos-Picot
Publisher : Springer Science & Business Media
ISBN 13 : 3662225166
Total Pages : 391 pages
Book Rating : 4.6/5 (622 download)
Download or read book The Role of Oxidative Stress in Neuronal Death written by Irene Ceballos-Picot and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines current knowledge and recent advances in the study of fundamental processes involved in neuronal death, particularly oxidative stress as a causal agent or risk factor. The author presents discussion of oxidative stress in neuronal apoptosis and its role in the neuropathogenesis of age-related neurodegenerative diseases exemplified by Alzheimer's disease, Parkinson's disease and Amyotrophic Lateral Sclerosis.
Author : John Donegan
Publisher : CRC Press
ISBN 13 : 9814316059
Total Pages : 250 pages
Book Rating : 4.8/5 (143 download)
Download or read book Cadmium Telluride Quantum Dots written by John Donegan and published by CRC Press. This book was released on 2013-12-03 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the last two decades, semiconductor quantum dots—small colloidal nanoparticles—have garnered a great deal of scientific interest because of their unique properties. Among nanomaterials, CdTe holds special technological importance as the only known II–VI material that can form conventional p–n junctions. This makes CdTe very important for the development of novel optoelectronic devices such as light-emitting diodes, solar cells, and lasers. Moreover, the demand for water-compatible light emitters and the most common biological buffers give CdTe quantum dots fields a veritable edge in biolabeling and bioimaging. Cadmium Telluride Quantum Dots: Advances and Applications focuses on CdTe quantum dots and addresses their synthesis, assembly, optical properties, and applications in biology and medicine. It makes for a very informative reading for anyone involved in nanotechnology and will also benefit those scientists who are looking for a comprehensive account on the current state of quantum dot–related research.
Author : Dirk Inze
Publisher : CRC Press
ISBN 13 : 0203303148
Total Pages : 417 pages
Book Rating : 4.2/5 (33 download)
Download or read book Oxidative Stress in Plants written by Dirk Inze and published by CRC Press. This book was released on 2001-10-18 with total page 417 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plants depend on physiological mechanisms to combat adverse environmental conditions, such as pathogen attack, wounding, drought, cold, freezing, salt, UV, intense light, heavy metals and SO2. Many of these cause excess production of active oxygen species in plant cells. Plants have evolved complex defense systems against such oxidative stress. The
Author : H.J. Forman
Publisher : Springer Science & Business
ISBN 13 : 0306484129
Total Pages : 432 pages
Book Rating : 4.3/5 (64 download)
Download or read book Signal Transduction by Reactive Oxygen and Nitrogen Species: Pathways and Chemical Principles written by H.J. Forman and published by Springer Science & Business. This book was released on 2006-02-17 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Henry Jay Forman, Jon Fukuto and Martine Torres "Research is to see what everybody else has seen and to think what nobody else has thought. " -- Albert Szent-Gyorgyi Several years ago, one of us put together a book that dealt with various aspects of oxidative stress and introduced the concept of signal transduction by oxidants. Since then, the interest in the mechanisms by which reactive oxygen and nitrogen species (ROS/RNS) can modulate the cell’s response has tremendously grown, paralleling the intense efforts towards identifying new signaling pathways in which phosphorylation/dephosphorylation events take center stage. Evidence is now mounting that production of these species by the cells is required for their function from growth to apoptosis and numerous signaling pathways have been identified where the participation of ROS and RNS is apparent (see Chapters 11-14, 16 and 18). Thus, the field is no more limited to the group of free radical aficionados who have pioneered this area of research but has now gone mainstream. While it is satisfactory for those of us who have been working on this topic for a long time, it has the risk of becoming the “fashionable” motto where those molecules, still mysterious to some, become responsible for everything and anything.
Author : Guy C. Brown
Publisher :
ISBN 13 :
Total Pages : 248 pages
Book Rating : 4.4/5 (91 download)
Download or read book Mitochondria and Cell Death written by Guy C. Brown and published by . This book was released on 1999 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Filip Cristiana
Publisher : BoD – Books on Demand
ISBN 13 : 1789231345
Total Pages : 218 pages
Book Rating : 4.7/5 (892 download)
Download or read book Reactive Oxygen Species (ROS) in Living Cells written by Filip Cristiana and published by BoD – Books on Demand. This book was released on 2018-05-23 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oxygen represents only 20% of the Earth's atmosphere, yet it is vital for the survival of aerobic organisms. There is a dark part of the use of oxygen that consists in generating reactive species that are potentially harmful to living organisms. Moreover, reactive oxygen species can combine with nitrogen derivatives and generate many other reactive species. Thus, living organisms are continuously assaulted by reactive species from external or internal sources. However, the real danger comes in the case of high concentrations and prolonged exposure to these species. This book presents an image of the mechanisms of action of reactive species and emphasizes their involvement in diseases. Inflammation and cancer are examined to determine when and how reactive species turn the evolution of a benign process to a malignant one. Some answers may come from recent studies indicating that reactive species are responsible for epigenetic changes.
Author : Mohinder Bansal
Publisher : Springer
ISBN 13 : 8132220323
Total Pages : 183 pages
Book Rating : 4.1/5 (322 download)
Download or read book Oxidative Stress Mechanisms and their Modulation written by Mohinder Bansal and published by Springer. This book was released on 2014-10-17 with total page 183 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research over the years has demonstrated that free radicals mediated oxidative stress lies at the helm of almost all patho-physiological phenomena. These findings emphasize on the need to understand the underlying molecular mechanism(s) and their critical role in the pathogenesis. This book aims to focus on these areas to provide readers a comprehensive outlook about the major redox sensitive pathways and networks involved in various disease conditions. In the first chapter of the book, basic information about the oxidative stress, its generation, its biomarkers and its role in body are discussed. In the next three chapters, the role of oxidative stress in various pathologies ranging from neurological disorders, to cardiovascular diseases, cancers, metabolic diseases and ageing have been described. Chapter 5 cumulatively describes the most important molecular signaling pathways that are affected by reactive oxygen species (ROS). These are the mechanisms which are common denominators in various pathological states. In the next part of the book, various antioxidant strategies to target and mitigate ROS have been discussed with details on the mechanisms. Selenium, being the research focus and interest of the authors for years, the role of selenium as an antioxidant as part of selenoproteins has been included in the book. Finally, the book culminates with authors’ perspective on the future of the redox biology field. Throughout the book, efforts have been made to use simplified language and suitable figures for ease to understand the contents. Although the authors have tried to touch on all the different aspects of oxidative stress in detail, the fact that it is a continuously growing field with updates coming every day, there might be some areas which might not be described in depth. This book is designed for students, young scientists to get acquainted with the redox biology. Overall, this book is a reference to understand the redox regulation of cellular signaling pathways involved in pathogenesis.
Author : Nežka Kavčič
Publisher :
ISBN 13 :
Total Pages : 95 pages
Book Rating : 4.:/5 (19 download)
Download or read book Different types of cell death and the role of reactive oxygen species in cell death signalling written by Nežka Kavčič and published by . This book was released on 2018 with total page 95 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Scott R. Erlich
Publisher : Nova Publishers
ISBN 13 : 9781600214509
Total Pages : 246 pages
Book Rating : 4.2/5 (145 download)
Download or read book Frontiers in Cell Apoptosis Research written by Scott R. Erlich and published by Nova Publishers. This book was released on 2007 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: Apoptosis is the regulated form of cell death. It is a complex process defined by a set of characteristic morphological and biochemical features that involves the active participation of affected cells in a self-destruction cascade. This book provides studies in the field of apoptosis research.
Author : Rajendra Prasad
Publisher : Springer Science & Business Media
ISBN 13 : 3642752535
Total Pages : 273 pages
Book Rating : 4.6/5 (427 download)
Download or read book Candida Albicans written by Rajendra Prasad and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: Candida, which was discovered more than a century ago as a causative organism of oral thrush, is now thought to potentially infect almost every tissue of the human body. Although we still do not have a safe anti-candida drug, the growing pace of progess of research on Candida albicans holds promise that a breakthrough is imminent. Though many monographs and articles on candida and candidoses have appeared in recent years, they mostly cover the clinical aspects. This particular text, however, explains the more basic features of candida including the molecular genetics, molecular biology and immunology of the cell wall, the molecular basis of morphogenesis and the structure and function of the plasma membrane. The role of anti-candida drugs and their mechanism of action are also discussed.
